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1. 发明授权

US06669196B1 Public health oriented board game system 失效
标题翻译：公共卫生导向的棋盘游戏系统
公开(公告)号：US06669196B1
公开(公告)日：2003-12-30
申请号：US10162820
申请日：2002-06-06
申请人： Rita Washko
发明人： Rita Washko
IPC分类号： A13F300
CPC分类号： A63F3/0478 , A63F2003/00018 , A63F2003/0492 , A63F2009/0484
摘要： A board game system comprising: (i) a game board having a plurality of squares to define a path of travel; (ii) a plurality of tokens representing each player's position on the path of travel around the game board; (iii) a plurality of playing cards, having questions, and a plurality of potential answers, one of which is correct, the playing cards adapted to be selected randomly by the players whereby a player answers a question correctly to move the token accordingly; (iv) a plurality of “Anti-Hazard” cards, awarded to a player who lands on a single designated game board square, which can be used by a player to avoid getting pulled into a plurality of Hazard Traps; (v) two dice, including a first die with a plurality of spots controlling the number of squares which can be advanced by a player when a player answers a question correctly, the second die having a plurality of drawings, controlling whether a player escapes from a plurality of Hazard Traps; and (vi) an Information Booklet having a plurality of board game rules and instructions, background information on health-related topics, and references for each individual question on a playing card.
摘要翻译：一种棋盘游戏系统，包括：（i）具有多个方块以定义旅行路线的游戏板; （ii）表示每个玩家在游戏板周围的行进路径上的位置的多个令牌; （iii）具有问题的多个扑克牌和多个潜在的答案，其中一个是正确的，适合于由玩家随机选择的玩家牌，由此玩家可以正确地回答问题以相应地移动令牌; （iv）授予在单个指定游戏棋盘平台上的玩家的多个“防危险”牌，玩家可以使用该牌，以避免被拉入多个危险陷阱; （v）两个骰子，包括具有多个点的第一模具，当玩家正确地回答问题时，控制玩家可以提前的方格数，第二模具具有多个附图，控制玩家是否从多个危险陷阱; 和（vi）具有多个板游戏规则和指令的信息手册，关于健康相关主题的背景信息以及扑克牌上的每个单独问题的参考。

2. 发明授权

US07335158B2 Surgical devices for imposing a negative pressure to stabilize the cardiac tissue during surgery 失效
标题翻译：用于在手术期间施加负压以稳定心脏组织的手术装置
公开(公告)号：US07335158B2
公开(公告)日：2008-02-26
申请号：US10216616
申请日：2002-08-08
申请人： Charles S. Taylor
发明人： Charles S. Taylor
IPC分类号： A61F2/00 , A13F13/00 , A61B17/00 , A61B19/00
CPC分类号： A61B17/0218 , A61B17/00 , A61B90/40 , A61B2017/00243 , A61B2017/00703 , A61B2017/0243 , A61B2017/306 , A61B2017/3488
摘要： The invention is devices and techniques which use a negative (suction) pressure or vacuum, applied through a surgical instrument, to fix the position of a portion of the surface of a beating heart so that a surgical procedure can be more easily performed. The devices apply a negative pressure at several points on the outer surface of the heart such that a portion of the heart is fixed in place by the suction imposed through the surgical instrument. Because the instrument fixes the position of the tissue, and because the instruments remain at a constant distance from the particular portion of the heart where the surgery is being performed, the device may also serve as a support or platform so that other surgical instruments or devices can be advantageously used at the site. In certain preferred embodiments, the devices described herein have structures to facilitate the use of additional surgical instruments such that the placement of negative pressure device permit the surgeon to advantageously manipulate the other instruments during surgery. The negative pressure is preferably imposed through a plurality of ports which may be disposed in a substantially planar surface of the instrument which contacts the cardiac tissue.
摘要翻译：本发明是使用通过外科器械施加的负（吸力）压力或真空来固定跳动心脏表面的一部分的位置使得外科手术可以更容易地进行的装置和技术。这些装置在心脏的外表面上的几个点处施加负压，使得心脏的一部分通过通过手术器械施加的抽吸被固定就位。因为仪器固定组织的位置，并且因为仪器保持与正在执行手术的心脏的特定部分恒定的距离，所以该装置还可以用作支撑或平台，使得其它手术器械或装置可以有利地在现场使用。在某些优选实施例中，本文所述的装置具有便于使用额外外科器械的结构，使得负压装置的放置允许外科医生在手术期间有利地操纵其他器械。负压优选通过多个端口施加，所述多个端口可以设置在与心脏组织接触的仪器的基本平坦的表面中。

3. 发明授权

US6151807A Health care shoe 失效
标题翻译：保健鞋
公开(公告)号：US6151807A
公开(公告)日：2000-11-28
申请号：US240791
申请日：1999-01-30
申请人： Yi-Ming Qui , David Liu , Joanne Yang
发明人： Yi-Ming Qui , David Liu , Joanne Yang
IPC分类号： A43B7/00 , A61F5/14 , A13B7/06
CPC分类号： A43B7/146 , A43B1/0054 , A43B7/00
摘要： A health care shoe, which can continuously provide adequate magnetic field arranged to penetrate through the wearer's foot for improving the wearer's blood circulation and metabolism, includes a sole having a plurality of magnet cavities specifically indented and distributed on an inner surface thereof, a shoe body which includes a vamp and sides rigidly attached on top of the sole to define a foot chamber between the shoe body and the sole; an insole placed on the sole inside the foot chamber; a plurality of base magnet elements fittingly received in the magnet cavities respectively; and a plurality of upper magnet elements embedded inside the shoe body with respect to the positions of the base magnet elements, wherein the upper magnet elements are arranged to enable magnetic fields flowing between the base magnet elements and the upper magnet elements. Moreover, the sole further has at least a medicine receiving cavity to receive a medicine unit which contains a medicine tablet made of painkiller or Chinese medical herb being incased therein. The medicine unit further includes a bottom magnet element positioned thereunder so as to produce magnetic filed around the medicine unit.
摘要翻译：一种能够连续地提供足够的磁场以穿透穿戴者的脚部以改善佩戴者的血液循环和新陈代谢的保健鞋，包括具有多个在其内表面上凹进并分布的磁体空腔的鞋底，鞋体其包括鞋面和刚性地附接在鞋底顶部上的侧边，以在鞋身和鞋底之间限定脚室; 放置在脚室内的鞋底上的鞋垫; 多个基本磁体元件分别适配地容纳在磁体腔中; 以及相对于所述基体磁体元件的位置嵌入到所述鞋体内的多个上部磁体，其中，所述上部磁体元件被布置成使得能够在所述基础磁体元件和所述上部磁体元件之间流动的磁场。此外，鞋底还具有至少一个药物容纳腔，以容纳药物单元，该药物单元含有由止痛药制成的药片或其中含有的中草药。药物单元还包括位于其下方的底部磁体元件，以便产生药物单元周围的磁场。

4. 发明授权

US07101544B1 Cholesterol-lowering agents, secondary bile acid production inhibitors, and foods and drinks 失效
标题翻译：胆固醇降低剂，二级胆汁酸生产抑制剂，食品和饮料
公开(公告)号：US07101544B1
公开(公告)日：2006-09-05
申请号：US10031569
申请日：2000-07-19
申请人： Haruji Sawada , Yasuto Yoshida , Yasue Wada , Kenji Ohishi , Masahiko Itoh , Wakae Yokoi , Tunekazu Watanabe
发明人： Haruji Sawada , Yasuto Yoshida , Yasue Wada , Kenji Ohishi , Masahiko Itoh , Wakae Yokoi , Tunekazu Watanabe
IPC分类号： A13C9/12 , A23L1/28
CPC分类号： A23L2/52 , A23L5/00 , A23L31/00 , A23L31/10 , A23L33/10 , A23L33/14 , A23V2002/00 , A61K36/064 , A23V2250/218
摘要： Secondary bile acid production inhibitors and cholesterol-lowering agents containing a yeast as the active ingredient.
摘要翻译：二级胆汁酸生成抑制剂和含有酵母作为活性成分的降胆固醇剂。

5. 发明授权

US06168496A Fabric-covered spring toy and method for producing 失效
标题翻译：织物覆盖的弹簧玩具和生产方法
公开(公告)号：US06168496A
公开(公告)日：2001-01-02
申请号：US09318977
申请日：1999-05-26
申请人： Yip Wing Kay Thomas
发明人： Yip Wing Kay Thomas
IPC分类号： A13H3300
CPC分类号： A63H3/02 , A63H3/04
摘要： A method is provided for producing a fabric-covered spring toy having a helical body which is decorated both on its outside and on its confronting helical surfaces. In the method, a fabric tube is everted using a lanyard to pull one end of the tube through the tube center to produce the fabric tube. Everting produces a tube with a decorative surface on the outer face. The resulting fabric covered spring body can be sewn to other fabric structures such as simulated animal body parts, for incorporation into an animal-like product having a semi-soft, flexible body.
摘要翻译：提供了一种用于生产织物覆盖的弹簧玩具的方法，其具有在其外部和相对的螺旋表面上装饰的螺旋体。在该方法中，使用系索将织物管旋转以将管的一端拉过管中心以产生织物管。 Everting在外表面上生产带有装饰表面的管。所形成的织物覆盖的弹簧体可以缝合到其他织物结构，例如模拟动物体部分，以便结合到具有半柔性，柔性体的动物样产品中。

6. 发明申请

WO2020198301A1 INHIBITOR OF MIGRATION OF CANCER CELLS AND METHODS OF TREATING CANCER CELLS METASTASIS 审中-公开
公开(公告)号：WO2020198301A1
公开(公告)日：2020-10-01
申请号：PCT/US2020/024610
申请日：2020-03-25
申请人： HOWARD UNIVERSITY , GEORGETOWN UNIVERSITY , ULLAH, Heyamet , DAKSHANAMURTHY, Sivanesan
发明人： ULLAH, Heyamet , DAKSHANAMURTHY, Sivanesan
IPC分类号： A13 , A61K31/4196 , A61P35/04
摘要： A method for treating against, or at least inhibiting or suppressing, the proliferation of a cancer involves administering a compound, a tautomer, or a pharmaceutically acceptable salt thereof, in an amount effective for inhibiting metastasis of cancer cells, wherein the compound is represented by the formula (1): wherein each R 1 is independent of the other and represents a halogen atom selected from the group consisting of bromo, chloro, fluoro and iodo.

7. 发明申请

WO2020198832A1 PEPTÍDEOS SINTÉTICOS COM AFINIDADE AO RECEPTOR DE TGF-Β, COMPOSIÇÃO FARMACÊUTICA E USO DOS MESMOS COMO IMUNOMUDULADORES NO TRATAMENTO DE DOENÇAS AUTOIMUNES, INFLAMATÓRIAS OU ALÉRGICAS 审中-公开
公开(公告)号：WO2020198832A1
公开(公告)日：2020-10-08
申请号：PCT/BR2020/050117
申请日：2020-04-06
申请人： UNIVERSIDADE FEDERAL DE UBERLÂNDIA , CIRINO ALBERTO GOULART EIRELI EPP (BIOGENETICS)
发明人： FILHO, Luiz Ricardo Goulart , FERREIRA-BRIZA, Fatima D. , VAZ, Emília Rezende , ARAUJO, Galber Rodrigues , VIEIRA, Carlos Ueira , AGLAS, Lorenz
IPC分类号： C07K7/08 , A13K38/10 , A61P29/00 , A61P37/02 , A61P37/08
摘要： A presente invenção refere-se à seleção e caracterização de peptídeos sintéticos, que possuem afinidade por receptores presentes em células do sistema imunológico, mais particularmente com afinidade ao receptor de TGF-β, bem como composições farmacêuticas e uso destes peptídeos para preparar medicamentos ou composições imunogências. Estes peptídeos sintéticos podem se ligar a receptores celulares e promover um perfil regulatório importante para o tratamento e/ou profilaxia de doenças aonde haja uma desordem imunológica, mais particularmente em que as doenças relacionadas a desordem imunológica são: doenças inflamatórias crônicas ou agudas, alérgicas e/ou auto-imunes.

8. 发明申请

WO2016149775A1 SHOE SOLE PROVIDED WITH REMOVABLE DECORATIVE COMPONENTS 审中-公开
标题翻译： SHOE SOLE提供可拆卸的装饰组件
公开(公告)号：WO2016149775A1
公开(公告)日：2016-09-29
申请号：PCT/BG2016/000007
申请日：2016-02-22
申请人： SLOKOSKI, Georgi, Vasilev
发明人： SLOKOSKI, Georgi, Vasilev
IPC分类号： A13B13/14
CPC分类号： A43B23/24 , A43B3/0078
摘要： A shoe sole provided with removable decorative components, which sole comprises a base member, having an external sidewall with an appropriate thickness and perimeter, wherein at least one groove is formed in the sidewall, the said groove is disposed around the perimeter of the said sidewall, in which groove an additional member, being a removable flexible element is attached by a protrusion formed on the removable flexible element.
摘要翻译：鞋底设置有可拆卸的装饰部件，鞋底包括基部构件，其具有适当厚度和周长的外侧壁，其中至少一个凹槽形成在侧壁中，所述凹槽围绕所述侧壁的周边设置，其中作为可移除的柔性元件的附加构件通过形成在可移除的柔性元件上的突起附接在该凹槽中。

9. 实用新型

KR200014498Y1 덧보습 失效
公开(公告)号：KR200014498Y1
公开(公告)日：1978-02-03
申请号：KR2019760000261
申请日：1976-01-16
申请人： 함명회사신흥기업사
发明人： 김호수
IPC分类号： A13

10. 实用新型

KR2019770000394Y1 덧보습 失效
公开(公告)号：KR2019770000394Y1
公开(公告)日：1977-10-20
申请号：KR2019760000261
申请日：1976-01-16
申请人： 함명회사신흥기업사
发明人： 김호수
IPC分类号： A13

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