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    • 9. 发明申请
    • TOPICAL COMPOSITIONS HAVING IMPROVED SKIN FEEL
    • 具有改善皮肤感觉的主题组合物
    • WO1997003647A1
    • 1997-02-06
    • PCT/US1996011788
    • 1996-07-17
    • THE PROCTER & GAMBLE COMPANY
    • THE PROCTER & GAMBLE COMPANYMcATEE, David, MichaelALBACARYS, Lourdes, DessusHASENOEHRL, Eric, JohnLISTRO, Joseph, Anthony
    • A61K07/50
    • A61K8/442A61K8/416A61K8/463A61K8/466A61K2800/596Y10S514/844Y10S516/04Y10S516/05Y10S516/07
    • The compositions of the present invention are useful for topical application to human skin. These compositions provide improved skin feel. These compositions can be in the form of leave-on products or products that are rinsed or wiped from the skin after use. These compositions are also useful for conditioning, desquamating, and cleansing the skin and for relieving dry skin. A topical personal care composition comprising: (a) from 0.1 % to 20 % by weight of an amphoteric surfactant having the structure (I) wherein R is unsubstituted, saturated or unsaturated, straight or branched chain alkyl having from 9 to 22 carbon atoms; m is an integer from 1 to 3; n is 0 or 1; R and R are independently selected from alkyl having from 1 to 3 carbon atoms and monohydroxyalkyl having from 1 to 3 carbon atoms; R is selected from saturated or unsaturated alkyl having from 1 to 5 carbon atoms and saturated or unsaturated monohydroxyalkyl having from 1 to 5 carbon atoms; X is selected from the group consisting of CO2, SO3, and SO4; and pharmaceutically acceptable salts of the foregoing compounds; (b) from 0.1 % to 20 % by weight of an anionic surfactant; (c) from 0.1 % to 15 % by weight of a cationic surfactant; and (d) from 0.1 % to 99.7 % by weight water.
    • 本发明的组合物可用于局部施用于人皮肤。 这些组合物提供改善的皮肤感觉。 这些组合物可以是在使用后从皮肤上漂洗或擦拭的产品或产品的形式。 这些组合物也可用于调理,脱皮和清洁皮肤和缓解皮肤干燥。 一种局部个人护理组合物,其包含:(a)0.1重量%至20重量%的具有结构(I)的两性表面活性剂,其中R 1为未取代的饱和或不饱和的直链或支链烷基,其具有9至22 碳原子 m为1〜3的整数; n为0或1; R 2和R 3独立地选自具有1至3个碳原子的烷基和具有1至3个碳原子的单羟基烷基; R 4选自具有1至5个碳原子的饱和或不饱和烷基和具有1至5个碳原子的饱和或不饱和单羟基烷基; X选自CO 2,SO 3和SO 4; 和上述化合物的药学上可接受的盐; (b)0.1〜20重量%的阴离子表面活性剂; (c)0.1〜15重量%的阳离子表面活性剂; 和(d)0.1重量%至99.7重量%的水。