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    • 7. 发明申请
    • METHOD OF SPRAY DRYING
    • 喷雾干燥方法
    • WO02006538A1
    • 2002-01-24
    • PCT/GB2001/003120
    • 2001-07-11
    • C13B30/02C13F1/02
    • C13B30/028
    • This invention relates to a spray drying process which is particularly suitable for spray-drying sugars such as sucrose. The process comprises providing a dispersion of a first material in a liquid solvent at a concentrating of form 10 to 50 % w/v; providing finely divided solid particles of a second material; spray drying the dispersion while continuously introducing the finely divided solid particles into the spray drier in an amount of from 10 to 99 % by weight, based on the weight of the final product; whereby the process produces composite particles consisting of spray-dried matrix of the first material bonded to particles of the second material.
    • 本发明涉及一种特别适用于喷雾干燥糖如蔗糖的喷雾干燥方法。 该方法包括以10至50%w / v的浓度提供第一种材料在液体溶剂中的分散体; 提供细分散的第二材料的固体颗粒; 喷雾干燥分散体,同时以最终产品的重量计,以10至99重量%的量将细碎的固体颗粒连续地引入喷雾干燥器中; 由此该方法产生由与第二材料的颗粒结合的第一材料的喷雾干燥基质组成的复合颗粒。
    • 8. 发明申请
    • METHOD FOR PRODUCING A CRYSTALLINE TABLETING ADDITIVE, ADDITIVE THUS OBTAINED AND USE THEREOF
    • 生产结晶添加剂的方法,获得的添加剂及其用途
    • WO02008470A1
    • 2002-01-31
    • PCT/EP2001/008394
    • 2001-07-19
    • A23L1/00A61K9/20A61K47/26C13B30/02C13K5/00
    • C13B30/028A61K9/2018A61K47/26C13K5/00
    • The present invention relates to a method for producing a tableting additive, which method comprises providing a spray dried tableting additive in particulate form which particles at least partially consist of amorphous additive material and at least partially of crystalline additive material; and crystallising the amorphous additive material by subjecting the particles for a short time and under agitation to a temperature between 30 and 100 DEG C at a relative humidity between 60 and 25 %. More in particular, the relationship between relative humidity and temperature is defined by the formula: % relative humidity = 218-47*Ln(T( DEG C)), wherein T( DEG C) is the temperature to which the particles are subjected.
    • 本发明涉及一种压片添加剂的制造方法,该方法包括提供颗粒形式的喷雾干燥的压片添加剂,该颗粒至少部分地由无定形添加剂材料组成并且至少部分地由结晶添加剂材料组成; 并通过在短时间和搅拌下将颗粒在相对湿度为60至25%之间的温度下在30至100℃之间进行结晶而使无定形添加剂材料结晶。 更特别地,相对湿度和温度之间的关系由下式定义:%相对湿度= 218-47 * Ln(T(℃)),其中T(℃)是颗粒经受的温度。
    • 9. 发明申请
    • PROCESS FOR DRYING HIGH-LACTOSE AQUEOUS FLUIDS
    • 用于干燥高乳糖水溶液的方法
    • WO2003075643A2
    • 2003-09-18
    • PCT/US2003/006588
    • 2003-03-03
    • KELLER TECHNOLOGIES, INC.KELLER, A. Kent
    • KELLER, A. Kent
    • A01J
    • C13B30/028C13K5/00
    • Systems and methods for processing a high-lactose aqueous fluid (HLAF), such as permeate from ultrafiltration of whey fluid, are described. The preferred process includes concentrating HLAF containing from about 1 to about 35% solids, wherein at least 50% of the solids are lactose, to form a concentrated HLAF containing from about 45 to about 65% solids; further concentrating the HLAF to form a highly concentrated HLAF containing from about 70 to about 80% solids; cooling the highly concentrated HLAF with a gaseous fluid to create a cooling, concentrating, crystallizing cascade to further concentrate the HLAF to form a partially monohydrate. An air-lift dryer having diverging sidewalls and methods of using same are also
    • 描述了用于处理高乳糖含水流体(HLAF)(3)的系统和方法,例如来自乳清液超滤的渗透物。 优选的方法包括浓缩含有约1至约35%固体的HLAF(3),其中至少50%的固体为乳糖,以形成含有约45至约65%固体的浓缩HLAF(3) 进一步浓缩HLAF(3)以形成含有约70至约80%固体的高度浓缩的HLAF(3) 用气态流体冷却高度浓缩的HLAF(3)以产生冷却,浓缩,结晶级联以进一步浓缩HLAF(3)以形成含约78至约88%固体的部分结晶的HLAF(3); 并在空气提升干燥器(24)中干燥部分结晶的HLAF(3)以形成富含结晶的α-乳糖一水合物的产物。 还公开了具有发散侧壁(32)的空气提升干燥器(24)及其使用方法。