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1. 发明授权

US09399614B2 Conjugated diene acids and derivatives thereof 有权
标题翻译：共轭二烯酸及其衍生物
公开(公告)号：US09399614B2
公开(公告)日：2016-07-26
申请号：US14799218
申请日：2015-07-14
申请人： Elevance Renewable Sciences, Inc.
发明人： Ryan Littich , Charles Coburn
IPC分类号： A61K47/00 , B01F17/00 , A23D7/00 , C08F220/12 , A23D9/00 , C07C69/587 , C08F236/14 , C08F236/10 , C09F5/02 , A01N25/04 , C11C3/00 , C11C3/14 , C09J4/00
CPC分类号： C07C69/587 , A01N25/04 , A23K20/158 , C08F236/10 , C08F236/14 , C08L9/00 , C08L9/06 , C09F5/02 , C09J4/00 , C11C3/003 , C11C3/14 , C08L47/00
摘要： Conjugated diene acids and derivatives thereof, are disclosed herein. In some embodiments, the conjugated diene acids and derivatives thereof are derived from the metathesis of a natural oil followed by isomerization. Uses of conjugated diene acids and derivatives thereof in various compositions are also disclosed herein.
摘要翻译：共轭二烯酸及其衍生物在此公开。在一些实施方案中，共轭二烯酸及其衍生物衍生自天然油的复分解，随后异构化。共轭二烯酸及其衍生物在各种组合物中的用途也在本文中公开。

2. 发明公开

EP0347509A1 A process of extraction and purification of polyunsaturated fatty acids from natural sources 失效
标题翻译： Verfahren zur Extraktion und Reinigung vonpolyungesättigtenFettsäurenaus Naturquellen。
公开(公告)号：EP0347509A1
公开(公告)日：1989-12-27
申请号：EP88401555.3
申请日：1988-06-21
申请人： CENTURY LABORATORIES INC.
发明人： Rubin David , Rubin Elyiahu J
IPC分类号： C07C57/03 , C07C51/42 , C11C1/00
CPC分类号： C09F5/02 , C09F5/10
摘要： To extract and purify polyunsaturated fatty acids, particularly EPA and DHA, without cis-trans conversion, from naturally occurring oils, such as marine animal oil and various vegetable oils, a mixture of free fatty acids is first extracted from the oil. The resulting mixture of pure fatty acids is then subjected to separation by means of urea complexing to remove saturated fatty acids and most mono-unsaturated fatty acids. Remaining solvent and urea are then removed from the filtrate which is then subjected to low temperature fractional crystallization in the presence of an organic solvent such as acetone. Substantially pure polyunsaturated fatty acids, especially EPA and DHA, can be separately precipitated by reducing the temperature of the filtrate in two steps. Alternatively, the volume of the filtrate is is reduced in two steps and cooled to form precipitates, which are removed. The final product is a mixture of substantially pure DHA and EPA.
摘要翻译：从天然存在的油（例如海洋动物油和各种植物油）提取和纯化多不饱和脂肪酸，特别是EPA和DHA，无顺反式转化，首先从油中提取游离脂肪酸的混合物。然后将所得的纯脂肪酸混合物通过尿素络合进行分离以除去饱和脂肪酸和大多数单不饱和脂肪酸。然后从滤液中除去剩余溶剂和尿素，然后在有机溶剂如丙酮存在下进行低温分级结晶。基本上纯的多不饱和脂肪酸，特别是EPA和DHA，可以通过两步降低滤液的温度来分别沉淀。或者，将滤液的体积分两步进行还原，并冷却以形成析出物，将其除去。最终产品是基本上纯的DHA和EPA的混合物。

3. 发明申请

US20160016882A1 Conjugated Diene Acids and Derivatives Thereof 有权
标题翻译：共轭二烯酸及其衍生物
公开(公告)号：US20160016882A1
公开(公告)日：2016-01-21
申请号：US14799218
申请日：2015-07-14
申请人： Elevance Renewable Sciences, Inc.
发明人： Ryan Littich , Charles Coburn
IPC分类号： C07C69/587 , C08F212/08 , A23K1/16 , C09F5/02 , A01N25/04 , C09J4/00 , C08F236/14 , C08F236/10
CPC分类号： C07C69/587 , A01N25/04 , A23K20/158 , C08F236/10 , C08F236/14 , C08L9/00 , C08L9/06 , C09F5/02 , C09J4/00 , C11C3/003 , C11C3/14 , C08L47/00
摘要： Conjugated diene acids and derivatives thereof, are disclosed herein. In some embodiments, the conjugated diene acids and derivatives thereof are derived from the metathesis of a natural oil followed by isomerization. Uses of conjugated diene acids and derivatives thereof in various compositions are also disclosed herein.
摘要翻译：共轭二烯酸及其衍生物在此公开。在一些实施方案中，共轭二烯酸及其衍生物衍生自天然油的复分解，随后异构化。共轭二烯酸及其衍生物在各种组合物中的用途也在本文中公开。

4. 发明授权

US4792418A Method of extraction and purification of polyunsaturated fatty acids from natural sources 失效
标题翻译：从天然来源提取和纯化多不饱和脂肪酸的方法
公开(公告)号：US4792418A
公开(公告)日：1988-12-20
申请号：US810550
申请日：1985-12-19
申请人： David Rubin , Elyiahu J. Rubin
发明人： David Rubin , Elyiahu J. Rubin
IPC分类号： C09F5/02 , C09F5/10 , C09F5/00
CPC分类号： C09F5/10 , C09F5/02
摘要： To extract and purify of polyunsaturated fatty acids, particularly EPA and DHA, without cis-trans conversion, from naturally occurring oils, such as marine animal oil and various vegetable oils a mixture of free fatty acids is first extracted from the oil. The resulting mixture of pure fatty acids is then subjected to separation by means of urea complexing to remove saturated fatty acids and most mono-unsaturated fatty acids. Remaining solvent and urea are then removed from the filtrate which is then subjected to low temperature fractional crystallization in the presence of an organic solvent such as acetone. Substantially pure polyunsaturated fatty acids, especially EPA and DHA, can be separately precipitated by reducing the temperature of the filtrate in two steps. Alternatively, the volume of the filtrate is reduced in two steps and cooled to form precipitates, which are removed. The final product is a mixture of substantially pure DHA and EPA.
摘要翻译：从天然存在的油（例如海洋动物油和各种植物油）中提取和纯化多不饱和脂肪酸，特别是EPA和DHA，不经顺反式转化，首先从油中提取游离脂肪酸的混合物。然后将所得的纯脂肪酸混合物通过尿素络合进行分离，以除去饱和脂肪酸和大多数单不饱和脂肪酸。然后从滤液中除去剩余的溶剂和尿素，然后在有机溶剂如丙酮存在下进行低温分级结晶。基本上纯的多不饱和脂肪酸，特别是EPA和DHA，可以通过两步降低滤液的温度来分别沉淀。或者，将滤液的体积分两步降低，并冷却形成析出物，将其除去。最终产品是基本上纯的DHA和EPA的混合物。

5. 发明授权

US3873585A Process for the recovery of polymeric acids from clays 失效
标题翻译：从粘土中回收聚合酸的方法
公开(公告)号：US3873585A
公开(公告)日：1975-03-25
申请号：US38026173
申请日：1973-07-18
申请人： EMERY INDUSTRIES INC
发明人： STURWOLD ROBERT J , SHARKEY HUBERT J
IPC分类号： C07C57/02 , C07C51/00 , C07C51/353 , C07C51/43 , C07C67/00 , C09F5/02 , C11B3/14 , C11B13/04 , C11C1/08 , C09F7/06 , C11C3/00
CPC分类号： C09F5/02 , C11C1/08
摘要： An aqueous process for the recovery of polymeric fatty acids from crystalline clay minerals including catalyst and bleaching clays is provided. The process involves contacting the clay containing the polymeric acid with a sufficient quantity of water and agitating to displace the polymeric acid, and when the displacement is essentially complete, recovering the polymeric fatty acid from the water and clay. An additional feature of this invention is the reuse of the clay for catalyst or bleaching purposes.
摘要翻译：提供了一种用于从包括催化剂和漂白粘土在内的结晶粘土矿物中回收聚合脂肪酸的水性方法。该方法包括将含有聚合酸的粘土与足够量的水接触并搅拌以置换聚合酸，并且当置换基本上完成时，从水和粘土回收聚合的脂肪酸。本发明的另一个特征是用于催化剂或漂白目的的粘土的再利用。

6. 发明申请

WO2016014287A1 CONJUGATED DIENE ACIDS AND DERIVATIVES THEREOF 审中-公开
标题翻译：联合二烯酸及其衍生物
公开(公告)号：WO2016014287A1
公开(公告)日：2016-01-28
申请号：PCT/US2015/040340
申请日：2015-07-14
申请人： ELEVANCE RENEWABLE SCIENCES, INC.
发明人： LITTICH, Ryan , COBURN, Charles
IPC分类号： C07C69/587 , C07C69/52 , C07C69/017
CPC分类号： C07C69/587 , A01N25/04 , A23K20/158 , C08F236/10 , C08F236/14 , C08L9/00 , C08L9/06 , C09F5/02 , C09J4/00 , C11C3/003 , C11C3/14 , C08L47/00
摘要： Conjugated diene acids and derivatives thereof, are disclosed herein. In some embodiments, the conjugated diene acids and derivatives thereof are derived from the metathesis of a natural oil followed by isomerization. Uses of conjugated diene acids and derivatives thereof in various compositions are also disclosed herein.
摘要翻译：共轭二烯酸及其衍生物在此公开。在一些实施方案中，共轭二烯酸及其衍生物衍生自天然油的复分解，随后异构化。共轭二烯酸及其衍生物在各种组合物中的用途也在本文中公开。

7. 发明专利

JPS5935958B2 JPS5935958B2 - 失效
公开(公告)号：JPS5935958B2
公开(公告)日：1984-08-31
申请号：JP8180274
申请日：1974-07-18
申请人： Emery Industries Inc
发明人： ROBAATO JEI SUTAAUORUDO , HABAATO JEI SHAAKEI
IPC分类号： C07C57/02 , C07C51/00 , C07C51/353 , C07C51/43 , C07C67/00 , C09F5/02 , C11B3/14 , C11B13/04 , C11C1/08
CPC分类号： C09F5/02 , C11C1/08

8. 发明公开

KR20180050331A 증가된 안정성 및 개선된 흡수율을 갖는 호노키올 및 마그놀롤 제형, 및 이의 사용 방법 审中-公开
公开(公告)号：KR20180050331A
公开(公告)日：2018-05-14
申请号：KR20187007412
申请日：2016-01-18
IPC分类号： A61K9/00 , A61K9/48 , A61K31/685 , A61K35/60 , A61K36/575 , A61P25/20
CPC分类号： A61K31/685 , A61K35/00 , A61K35/60 , A61K36/575 , C09F5/02 , A61K2300/00
摘要： 본발명은불면증또는안절부절증을치료하거나, 관리하거나, 예방하거나, 포커스(focus) 또는집중력을증가시키거나불안감을감소시키기위한제형및 방법에관한것이다. 제형은하나이상의다중불포화지방산, 예컨대버진연어오일(virgin salmon 오일)에서발견되는것들과혼합하여목련나무껍질추출물에존재하는호노키올(honokiol) 및마그놀롤(magnolol)을포함한다. 호노키올및 마그놀롤의다른지질제형과비교할때, 제형은개선된안정성및 증가된흡수율을나타낸다.

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