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1. 发明申请

US20040179427A1 Method and apparatus for chemical analysis 审中-公开
标题翻译：化学分析方法和装置
公开(公告)号：US20040179427A1
公开(公告)日：2004-09-16
申请号：US10480045
申请日：2004-04-28
发明人： Takeo Yamazaki , Naoto Mihashi , Takeshi Imamura , Satoko Omizu
IPC分类号： B01F013/02 , B01J019/24 , B01L003/00
CPC分类号： B01F13/0059 , B01F7/00291 , B01F13/02 , B01F15/00487 , B01F15/00551 , B01F2215/0431 , B01F2215/044 , B01F2215/0477
摘要： A method of mixing plural liquids in a liquid chamber is provided which comprises steps of introducing plural liquids into the liquid chamber, and repeating expansion and shrinkage of a bubble in the liquids in the liquid chamber. In this method, the liquid may be heated to produce the bubble. A liquid-mixing apparatus for mixing plural liquids in a liquid chamber to obtain a liquid mixture is also provided. The liquid-mixing apparatus comprises a liquid chamber; flow channels for introducing the plural liquids into the liquid chamber; a heating part placed in the liquid chamber for heating the liquid mixture in the liquid chamber; and an energy-supplying means for causing expansion and shrinkage of a bubble in the liquid mixture in the liquid chamber.
摘要翻译：提供了一种在液体室中混合多种液体的方法，其包括以下步骤：将多种液体引入液体室，并且重复液体室中的液体中的气泡的膨胀和收缩。在该方法中，可以加热液体以产生气泡。还提供了用于在液体室中混合多种液体以获得液体混合物的液体混合装置。液体混合装置包括液体室; 用于将多种液体引入液体室的流动通道; 放置在所述液体室中用于加热所述液体室中的液体混合物的加热部分; 以及用于引起液体室中的液体混合物中的气泡的膨胀和收缩的能量供应装置。

2. 发明公开

EP1466509A1 USE OF MULTIPLE OPTICAL VORTICES FOR PUMPINGa, MIXING AND SORTING 有权
标题翻译：采用光学MEHRFACHIGEN纺丝泵，混合和排序
公开(公告)号：EP1466509A1
公开(公告)日：2004-10-13
申请号：EP03703856.9
申请日：2003-01-07
申请人： The University of Chicago
发明人： CURTIS, Jennifer, E. , KOSS, Brian, A. , GRIER, David, G.
IPC分类号： H05H3/04
CPC分类号： H05H3/04 , B01F13/0052 , B01F15/00551 , B01L3/50273 , B01L3/502761 , B01L2200/0647 , B01L2200/0668 , B01L2400/0409 , B01L2400/0454 , F04B19/006 , G01N30/00 , G01N30/02 , G01N2015/149 , G02B21/32 , G03H1/0005 , G03H1/08 , G03H1/2294 , G03H2001/0077 , G03H2001/085 , G03H2225/32 , B01D2015/3895
摘要： A method for creating large numbers of high-quality optical traps in arbitrary three-dimensional configurations and dynamically reconfiguring the traps under computer control. The method uses computer-generated diffractive optical elements to convert one or more optical tweezers into one or more optical vortices. The method involves combining the optical vortex technique with the holographic optical tweezer technique to create multiple optical vortices in arbitrary configurations. The method also involves employing the rotation induced in trapped particles by optical vortices to assemble clusters of particles into functional micromachines, to drive previously assembled micromachines, to pump fluids through microfluidics channels, to control flows of fluids through microfluidics channels, to mix fluids within microfluidics channels, to transport particles, to sort particles and to perform other related manipulations and transformations on matter over length scales.

3. 发明授权

EP1466509B1 USE OF MULTIPLE OPTICAL VORTICES FOR PUMPING, MIXING AND SORTING 有权
标题翻译：采用光学MEHRFACHIGEN纺丝泵，混合和排序
公开(公告)号：EP1466509B1
公开(公告)日：2013-05-01
申请号：EP03703856.9
申请日：2003-01-07
申请人： The University of Chicago
发明人： CURTIS, Jennifer, E. , KOSS, Brian, A. , GRIER, David, G.
IPC分类号： G03H1/00 , G02B21/32 , H05H3/04 , G01N30/00 , F04B19/00 , B01F13/00 , B01F15/00
CPC分类号： H05H3/04 , B01F13/0052 , B01F15/00551 , B01L3/50273 , B01L3/502761 , B01L2200/0647 , B01L2200/0668 , B01L2400/0409 , B01L2400/0454 , F04B19/006 , G01N30/00 , G01N30/02 , G01N2015/149 , G02B21/32 , G03H1/0005 , G03H1/08 , G03H1/2294 , G03H2001/0077 , G03H2001/085 , G03H2225/32 , B01D2015/3895

4. 发明授权

US06995351B2 Multiple optical vortices for manipulating particles 失效
标题翻译：用于操纵颗粒的多重光学旋涡
公开(公告)号：US06995351B2
公开(公告)日：2006-02-07
申请号：US11059876
申请日：2005-02-17
申请人： Jennifer E. Curtis , Brian A. Koss , David G. Grier
发明人： Jennifer E. Curtis , Brian A. Koss , David G. Grier
IPC分类号： H01J40/14
CPC分类号： H05H3/04 , B01F13/0052 , B01F15/00551 , B01L3/50273 , B01L3/502761 , B01L2200/0647 , B01L2200/0668 , B01L2400/0409 , B01L2400/0454 , F04B19/006 , G01N30/00 , G01N30/02 , G01N2015/149 , G02B21/32 , G03H1/0005 , G03H1/08 , G03H1/2294 , G03H2001/0077 , G03H2001/085 , G03H2225/32 , B01D2015/3895
摘要： A method for creating large numbers of high-quality optical traps in arbitrary three-dimensional configurations and dynamically reconfiguring the traps under computer control. The method uses computer-generated diffractive optical elements to convert one or more optical tweezers into one or more optical vortices. The method involves combining the optical vortex technique with the holographic optical tweezer technique to create multiple optical vortices in arbitrary configurations. The method also involves employing the rotation induced in trapped particles by optical vortices to assemble clusters of particles into functional micromachines, to drive previously assembled micromachines, to pump fluids through microfluidics channels, to control flows of fluids through microfluidics channels, to mix fluids within microfluidics channels, to transport particles, to sort particles and to perform other related manipulations and transformations on matter over length scales.
摘要翻译：一种用于在任意三维配置中创建大量高质量光阱的方法，并在计算机控制下动态地重构陷阱。该方法使用计算机产生的衍射光学元件将一个或多个光学镊子转换成一个或多个光学旋转。该方法涉及将光学旋涡技术与全息光学镊子技术组合以产生任意配置的多个光学旋涡。该方法还涉及通过光学旋涡在捕获的颗粒中诱导的旋转，以将颗粒簇组装成功能微机械，驱动先前组装的微机械，通过微流体通道泵送流体，以控制流体通过微流体通道，将微流体中的流体混合通道，运输粒子，对粒子进行分类，并对长度尺度上的物质进行其他相关的操作和转换。

5. 发明申请

US20050173622A1 Multiple optical vortices for manipulating particles 失效
标题翻译：用于操纵颗粒的多重光学旋涡
公开(公告)号：US20050173622A1
公开(公告)日：2005-08-11
申请号：US11059876
申请日：2005-02-17
申请人： Jennifer Curtis , Brian Koss , David Grier
发明人： Jennifer Curtis , Brian Koss , David Grier
IPC分类号： G01N15/02 , B01J19/12 , G01N30/00 , G01N30/02 , G21K1/00 , H05H3/04 , G02B27/00
CPC分类号： H05H3/04 , B01F13/0052 , B01F15/00551 , B01L3/50273 , B01L3/502761 , B01L2200/0647 , B01L2200/0668 , B01L2400/0409 , B01L2400/0454 , F04B19/006 , G01N30/00 , G01N30/02 , G01N2015/149 , G02B21/32 , G03H1/0005 , G03H1/08 , G03H1/2294 , G03H2001/0077 , G03H2001/085 , G03H2225/32 , B01D2015/3895
摘要： A method for creating large numbers of high-quality optical traps in arbitrary three-dimensional configurations and dynamically reconfiguring the traps under computer control. The method uses computer-generated diffractive optical elements to convert one or more optical tweezers into one or more optical vortices. The method involves combining the optical vortex technique with the holographic optical tweezer technique to create multiple optical vortices in arbitrary configurations. The method also involves employing the rotation induced in trapped particles by optical vortices to assemble clusters of particles into functional micromachines, to drive previously assembled micromachines, to pump fluids through microfluidics channels, to control flows of fluids through microfluidics channels, to mix fluids within microfluidics channels, to transport particles, to sort particles and to perform other related manipulations and transformations on matter over length scales
摘要翻译：一种用于在任意三维配置中创建大量高质量光阱的方法，并在计算机控制下动态地重构陷阱。该方法使用计算机产生的衍射光学元件将一个或多个光学镊子转换成一个或多个光学旋转。该方法涉及将光学旋涡技术与全息光学镊子技术组合以产生任意配置的多个光学旋涡。该方法还涉及通过光学旋涡在捕获的颗粒中诱导的旋转，以将颗粒簇组装成功能微机械，驱动先前组装的微机械，通过微流体通道泵送流体，以控制流体通过微流体通道，将微流体中的流体混合通道，运输粒子，对粒子进行分类，并对长度尺度上的物质进行其他相关的操作和转换

6. 发明授权

US06737634B2 Use of multiple optical vortices for pumping, mixing and sorting 失效
标题翻译：使用多个光学旋涡进行泵送，混合和分选
公开(公告)号：US06737634B2
公开(公告)日：2004-05-18
申请号：US10050213
申请日：2002-01-16
申请人： Jennifer E. Curtis , Brian A. Koss , David G. Grier
发明人： Jennifer E. Curtis , Brian A. Koss , David G. Grier
IPC分类号： G01V800
CPC分类号： H05H3/04 , B01F13/0052 , B01F15/00551 , B01L3/50273 , B01L3/502761 , B01L2200/0647 , B01L2200/0668 , B01L2400/0409 , B01L2400/0454 , F04B19/006 , G01N30/00 , G01N30/02 , G01N2015/149 , G02B21/32 , G03H1/0005 , G03H1/08 , G03H1/2294 , G03H2001/0077 , G03H2001/085 , G03H2225/32 , B01D2015/3895
摘要： A method for creating large numbers of high-quality optical traps in arbitrary three-dimensional configurations and dynamically reconfiguring the traps under computer control. The method uses computer-generated diffractive optical elements to convert one or more optical tweezers into one or more optical vortices. The method involves combining the optical vortex technique with the holographic optical tweezer technique to create multiple optical vortices in arbitrary configurations. The method also involves employing the rotation induced in trapped particles by optical vortices to assemble clusters of particles into functional micromachines, to drive previously assembled micromachines, to pump fluids through microfluidics channels, to control flows of fluids through microfluidics channels, to mix fluids within microfluidics channels, to transport particles, to sort particles and to perform other related manipulations and transformations on matter over length scales
摘要翻译：一种用于在任意三维配置中创建大量高质量光阱的方法，并在计算机控制下动态地重构陷阱。该方法使用计算机产生的衍射光学元件将一个或多个光学镊子转换成一个或多个光学旋转。该方法涉及将光学旋涡技术与全息光学镊子技术组合以产生任意配置的多个光学旋涡。该方法还涉及通过光学旋涡在捕获的颗粒中诱导的旋转，以将颗粒簇组装成功能微机械，驱动先前组装的微机械，通过微流体通道泵送流体，以控制流体通过微流体通道，将微流体中的流体混合通道，运输粒子，对粒子进行分类，并对长度尺度上的物质进行其他相关的操作和转换

7. 发明授权

US07963691B2 Light pressure rotator and light pressure rotating device 失效
标题翻译：轻压转子和轻压旋转装置
公开(公告)号：US07963691B2
公开(公告)日：2011-06-21
申请号：US11632962
申请日：2005-07-21
申请人： Hiroo Ukita
发明人： Hiroo Ukita
IPC分类号： B01F7/18
CPC分类号： F03G6/00 , B01F7/0025 , B01F13/0059 , B01F15/00435 , B01F15/00551 , B81B3/0029 , B81B2201/038 , F03G6/06 , F03G7/00 , Y02E10/46 , Y02P70/32
摘要： The light pressure rotator (1) is the light pressure rotator being light pressure trapped by irradiation with light and light pressure rotating about the central axis O of rotation, characterized in that a reverse torque generating section generating a torque for rotating the rotator in the direction reverse to the predetermined direction is removed from a section arranged with three blades (2) each having a first side face (3) extending in the radial direction from the central axis O of rotation, a second side face (4) facing the central axis O of rotation, a third side face (5) facing the first side face (3), a lower surface (6) intersecting the central axis O of the rotation, and an upper surface (7) facing the lower surface (6). The light pressure rotating device comprises the light pressure rotator (1), a light source (C), and an objective (condenser) lens D.
摘要翻译：轻压旋转器（1）是轻压力旋转器，其是通过围绕中心轴线O旋转的光和轻压照射而被捕获的轻压力，其特征在于，产生用于使旋转器沿方向旋转的转矩的反转扭矩产生部从具有从旋转中心轴线O沿径向延伸的第一侧面（3）的三个叶片（2）布置的部分去除与预定方向相反的部分，第二侧面（4）面向中心轴线旋转的第三侧面（5），与第一侧面（3）相对的第三侧面（5），与旋转的中心轴线O相交的下表面（6）和面向下表面（6）的上表面（7）。轻压旋转装置包括轻压旋转器（1），光源（C）和物镜（聚光镜）D.

8. 发明申请

US20080031088A1 Light Pressure Rotator and Light Pressure Rotating Device 失效
标题翻译：轻压转子和轻压旋转装置
公开(公告)号：US20080031088A1
公开(公告)日：2008-02-07
申请号：US11632962
申请日：2005-07-21
申请人： Hiroo Ukita
发明人： Hiroo Ukita
IPC分类号： B01F7/00
CPC分类号： F03G6/00 , B01F7/0025 , B01F13/0059 , B01F15/00435 , B01F15/00551 , B81B3/0029 , B81B2201/038 , F03G6/06 , F03G7/00 , Y02E10/46 , Y02P70/32
摘要： The light pressure rotator (1) is the light pressure rotator being light pressure trapped by irradiation with light and light pressure rotating about the central axis O of rotation, characterized in that a reverse torque generating section generating a torque for rotating the rotator in the direction reverse to the predetermined direction is removed from a section arranged with three blades (2) each having a first side face (3) extending in the radial direction from the central axis O of rotation, a second side face (4) facing the central axis O of rotation, a third side face (5) facing the first side face (3), a lower surface (6) intersecting the central axis O of the rotation, and an upper surface (7) facing the lower surface (6). The light pressure rotating device comprises the light pressure rotator (1), a light source (C), and an objective (condenser) lens D.
摘要翻译：轻压旋转器（1）是轻压力旋转器，其是通过围绕中心轴线O旋转的光和轻压照射而被捕获的轻压力，其特征在于，产生用于使旋转器沿方向旋转的转矩的反转扭矩产生部从具有从旋转中心轴线O沿径向延伸的第一侧面（3）的三个叶片（2）布置的部分去除与预定方向相反的部分，面向中心轴线的第二侧面（4）旋转的第三侧面（5），与第一侧面（3）相对的第三侧面（5），与旋转的中心轴线O相交的下表面（6）和面向下表面（6）的上表面（7）。轻压旋转装置包括轻压旋转器（1），光源（C）和物镜（聚光镜）D.

9. 发明申请

US20040211889A1 Use of multiple optical vortices for pumping, mixing and sorting 失效
公开(公告)号：US20040211889A1
公开(公告)日：2004-10-28
申请号：US10847042
申请日：2004-05-17
申请人： The University of Chicago
发明人： Jennifer E. Curtis , Brian A. Koss , David G. Grier
IPC分类号： G01N021/85
CPC分类号： H05H3/04 , B01F13/0052 , B01F15/00551 , B01L3/50273 , B01L3/502761 , B01L2200/0647 , B01L2200/0668 , B01L2400/0409 , B01L2400/0454 , F04B19/006 , G01N30/00 , G01N30/02 , G01N2015/149 , G02B21/32 , G03H1/0005 , G03H1/08 , G03H1/2294 , G03H2001/0077 , G03H2001/085 , G03H2225/32 , B01D2015/3895
摘要： A method for creating large numbers of high-quality optical traps in arbitrary three-dimensional configurations and dynamically reconfiguring the traps under computer control. The method uses computer-generated diffractive optical elements to convert one or more optical tweezers into one or more optical vortices. The method involves combining the optical vortex technique with the holographic optical tweezer technique to create multiple optical vortices in arbitrary configurations. The method also involves employing the rotation induced in trapped particles by optical vortices to assemble clusters of particles into functional micromachines, to drive previously assembled micromachines, to pump fluids through microfluidics channels, to control flows of fluids through microfluidics channels, to mix fluids within microfluidics channels, to transport particles, to sort particles and to perform other related manipulations and transformations on matter over length scales

10. 发明申请

WO2004009226A1 METHOD AND APPARATUS FOR CHEMICAL ANALYSIS 审中-公开
标题翻译：化学分析方法与装置
公开(公告)号：WO2004009226A1
公开(公告)日：2004-01-29
申请号：PCT/JP2003/008760
申请日：2003-07-10
申请人： CANON KABUSHIKI KAISHA , YAMAZAKI, Takeo , MIHASHI, Naoto , IMAMURA, Takeshi , OMIZU, Satoko
发明人： YAMAZAKI, Takeo , MIHASHI, Naoto , IMAMURA, Takeshi , OMIZU, Satoko
IPC分类号： B01F13/00
CPC分类号： B01F13/0059 , B01F7/00291 , B01F13/02 , B01F15/00487 , B01F15/00551 , B01F2215/0431 , B01F2215/044 , B01F2215/0477
摘要： A method of mixing plural liquids in a liquid chamber is provided which comprises steps of introducing plural liquids into the liquid chamber, and repeating expansion and shrinkage of a bubble in the liquids in the liquid chamber. In this method, the liquid may be heated to produce the bubble. A liquid-mixing apparatus for mixing plural liquids in a liquid chamber to obtain a liquid mixture is also provided. The liquid-mixing apparatus comprises a liquid chamber (103); flow channels (104) for introducing the plural liquids into the liquid chamber; a heating part (106) placed in the liquid chamber for heating the liquid mixture in the liquid chamber; and an energy-supplying means for causing expansion and shrinkage of a bubble in the liquid mixture in the liquid chamber.
摘要翻译：提供了一种在液体室中混合多种液体的方法，其包括以下步骤：将多种液体引入液体室，并且重复液体室中的液体中的气泡的膨胀和收缩。在该方法中，可以加热液体以产生气泡。还提供了用于在液体室中混合多种液体以获得液体混合物的液体混合装置。液体混合装置包括液体室（103）; 用于将多种液体引入液体室的流路（104）放置在所述液体室中用于加热所述液体室中的液体混合物的加热部分（106）以及用于引起液体室中的液体混合物中的气泡的膨胀和收缩的能量供应装置。

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