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1. 发明授权

CN1148229C 接触镜片之碘处理用的双中和系统失效
公开(公告)号：CN1148229C
公开(公告)日：2004-05-05
申请号：CN96199744.3
申请日：1996-12-06
申请人：博士伦公司
发明人：吉尔·S·罗加尔斯基 , 戴维·J·海勒 , 艾利斯·K·杜比
IPC分类号： A61L2/18 , G02C13/00
CPC分类号： A61L12/105 , Y10S514/84
摘要：用碘消毒接触镜片的方法和系统，其中使用中和溶液，该溶液包括第一种快速中和组分和第二种缓慢中和组分，所述快速中和组分在少于5约秒的时间内完成其与已有碘的反应，而所述缓慢中和组分在约3-30分钟的时间内完成其与已有碘的反应。

2. 发明公开

CN1239438A 接触镜片之碘处理用的双中和系统失效
公开(公告)号：CN1239438A
公开(公告)日：1999-12-22
申请号：CN96199744.3
申请日：1996-12-06
申请人：博士伦公司
发明人：吉尔·S·罗加尔斯基 , 戴维·J·海勒 , 艾利斯·K·杜比
IPC分类号： A61L2/18 , G02C13/00
CPC分类号： A61L12/105 , Y10S514/84
摘要：用碘消毒接触镜片的方法和系统，其中使用中和溶液，该溶液包括第一种快速中和组分和第二种缓慢中和组分，所述快速中和组分在少于5约秒的时间内完成其与已有碘的反应，而所述缓慢中和组分在约3—30分钟的时间内完成其与已有碘的反应。

3. 发明公开

CN102118973A 一种眼科组合物中新的防腐剂替代物聚维酮碘无效复审申请
公开(公告)号：CN102118973A
公开(公告)日：2011-07-06
申请号：CN200980122263.7
申请日：2009-06-10
申请人：前瞻生物治疗公司
发明人： J·A·卡普里奥蒂 , B·梁 , C·M·萨姆森 , J·施泰因 , M·韦泽
IPC分类号： A01N45/00 , A61K31/56
CPC分类号： A01N43/36 , A61K9/0048 , A61K31/56 , A61K31/79 , A61K45/06 , A61L12/105 , A61K2300/00
摘要：本发明包括一种防腐的眼科制剂，该制剂包括浓度足以使所述眼科制剂防腐的聚维酮碘(PVP-I)，和至少有一种选自下的组分：甾体抗炎化合物，非甾体抗炎化合物，抗菌化合物，抗过敏的化合物和抗青光眼化合物。本发明还包括在眼科药剂中添加PVP-I以使该药剂防腐，其中加入的PVP-I的浓度足以使该药剂防腐。

4. 发明公开

CN101005863A 眼科设备的包装溶液无效复审申请
公开(公告)号：CN101005863A
公开(公告)日：2007-07-25
申请号：CN200580028548.6
申请日：2005-06-15
申请人：庄臣及庄臣视力保护公司
发明人： N·阿尔瓦雷斯-卡里甘 , S·布朗-斯克罗博特 , A·-M·W·迈尔斯 , F·尼利 , B·帕尔 , O·拉索尔
IPC分类号： A61L12/08 , C11D3/00
CPC分类号： A61L12/08 , A61L12/088 , A61L12/105
摘要：本发明涉及用于包装眼科设备的溶液，所述溶液包含至少一种Ksp小于约10－10的抗微生物金属盐，该溶液防止所述抗微生物金属盐在高压灭菌和保存过程中发生损失。

5. 发明申请

US20050117112A1 Antimicrobial lenses, processes to prepare them and methods of their use 失效
标题翻译：抗微生物镜片，制备方法和使用方法
公开(公告)号：US20050117112A1
公开(公告)日：2005-06-02
申请号：US10882072
申请日：2004-06-30
申请人： Alvarez-Carrigan Nayiby , Brown-Skrobot Susan , Ann-Marie Wong Meyers , Neely Frank , Pall Brian , Rathore Osman
发明人： Alvarez-Carrigan Nayiby , Brown-Skrobot Susan , Ann-Marie Wong Meyers , Neely Frank , Pall Brian , Rathore Osman
IPC分类号： A61L12/08 , C11D3/00 , G02C7/04
CPC分类号： A61L12/08 , A61L12/088 , A61L12/105
摘要： This invention relates to solutions for packaging ophthalmic devices comprising at least one antimicrobial metal salt which prevent the loss of said antimicrobial metal salt during autoclaving and storage.
摘要翻译：本发明涉及用于包装眼科装置的溶液，其包含至少一种抗微生物金属盐，其在高压灭菌和储存期间防止所述抗微生物金属盐的损失。

6. 发明授权

US6126706A Method of cleaning and disinfecting contact lens 失效
标题翻译：清洁和消毒隐形眼镜的方法
公开(公告)号：US6126706A
公开(公告)日：2000-10-03
申请号：US187133
申请日：1998-11-06
申请人： Satoru Matsumoto , Atsuko Sugiura
发明人： Satoru Matsumoto , Atsuko Sugiura
IPC分类号： G02C7/04 , A61L2/18 , A61L12/10 , C11D3/00 , C11D3/33 , C11D3/48 , G02C13/00 , B08B1/02 , C11D3/26 , C11D3/37
CPC分类号： C11D3/485 , A61L12/105 , C11D3/0078 , C11D3/33
摘要： A method of cleaning and disinfecting a contact lens, comprising the steps of: preparing a disinfectant which is an aqueous solution containing an iodine-complex polymer, and a diluent which is an aqueous solution containing ethylenediamine tetraacetic acid and/or soluble salts thereof, and a nonionic surface active agent; mixing the disinfectant and the diluent to provide a mixed solution, such that an available iodine concentration of the mixed solution immediately after mixing is in a range of 0.01-50 ppm, and such that concentrations of the ethylenediamine tetraacetic acid and/or the soluble salts thereof, and the nonionic surface active agent in the mixed solution are in a range of 0.0001-1.0 w/v % and in a range of 0.01-1.0 w/v %, respectively; and immersing the contact lens in the mixed solution for cleaning and disinfecting the contact lens, resulting in gradual reduction of the available iodine remaining in the mixed solution, by the ethylenediamine tetraacetic acid and/or the soluble salts thereof.
摘要翻译：一种清洁和消毒隐形眼镜的方法，包括以下步骤：制备作为含有碘络合物聚合物的水溶液的消毒剂和作为含有乙二胺四乙酸和/或其可溶性盐的水溶液的稀释剂，以及非离子表面活性剂; 将消毒剂和稀释剂混合以提供混合溶液，使得混合后立即混合溶液的有效碘浓度在0.01-50ppm范围内，使得乙二胺四乙酸和/或可溶性盐的浓度并且混合溶液中的非离子表面活性剂分别在0.0001-1.0w / v％的范围内和在0.01-1.0w / v％的范围内; 并将隐形眼镜浸入用于清洁和消毒隐形眼镜的混合溶液中，从而通过乙二胺四乙酸和/或其可溶性盐逐渐降低残留在混合溶液中的可用碘。

7. 发明申请

US20130064873A1 NUCLEATED TABLET FOR CONTACT LENS CLEANING, CONTACT LENS CLEANING PREPARATION CONTAINING SAME, AND METHOD FOR CLEANING CONTACT LENS 审中-公开
标题翻译：用于接触镜片清洁，接触镜片清洁准备的核心片，以及清洁接触镜片的方法
公开(公告)号：US20130064873A1
公开(公告)日：2013-03-14
申请号：US13521412
申请日：2011-01-14
申请人： Kazuhiro Sasanuma , Kazuhiro Tone
发明人： Kazuhiro Sasanuma , Kazuhiro Tone
IPC分类号： A01N25/34 , A01P1/00 , A01N55/00
CPC分类号： A61L12/082 , A01N25/34 , A61L12/105 , C11D3/0042 , C11D3/0052 , C11D3/0078 , C11D3/046 , C11D3/10 , C11D3/2086 , C11D3/3707 , C11D3/485 , C11D17/0039 , C11D17/0078 , A01N59/12
摘要： An object of the present invention is to provide a nucleated tablet for contact lens (CL) cleaning that makes it possible to disinfect a CL simply and easily in the presence of a foaming component; a CL cleaning preparation that contains the nucleated tablet; and a method for cleaning a CL. The nucleated tablet for CL cleaning of the invention is a nucleated tablet including an outer shell that contains iodine-based bactericide, a carbonate, an organic acid, and a surfactant having, per partial weight of 2000 out of the molecular weight thereof, less than one hydroxyl group, and an inner nucleus that contains a neutralizing agent, a carbonate, an organic acid, and a surfactant, wherein the inner nucleus is coated for extended release.
摘要翻译：本发明的目的是提供一种用于隐形眼镜（CL）清洁的成核片剂，其可以在发泡成分的存在下简单且容易地对CL进行消毒; 含有有核片的CL清洗剂; 以及清洁CL的方法。用于本发明的CL清洗的成核片剂是包含含有碘类杀菌剂，碳酸盐，有机酸和表面活性剂的外壳的成核片剂，其分子量分子量为2000，分子量小于一个羟基和含有中和剂，碳酸盐，有机酸和表面活性剂的内核，其中内核被涂覆以延长释放。

8. 发明授权

US07416737B2 Antimicrobial lenses, processes to prepare them and methods of their use 失效
标题翻译：抗微生物镜片，制备方法和使用方法
公开(公告)号：US07416737B2
公开(公告)日：2008-08-26
申请号：US10882072
申请日：2004-06-30
申请人： Nayiby Alvarez-Carrigan , Susan Brown-Skrobot , Ann-Marie Wong Meyers , Frank Neely , Brian Pall , Osman Rathore
发明人： Nayiby Alvarez-Carrigan , Susan Brown-Skrobot , Ann-Marie Wong Meyers , Frank Neely , Brian Pall , Osman Rathore
IPC分类号： A61K6/08
CPC分类号： A61L12/08 , A61L12/088 , A61L12/105
摘要： This invention relates to solutions for packaging ophthalmic devices comprising at least one antimicrobial metal salt which prevent the loss of said antimicrobial metal salt during autoclaving and storage.
摘要翻译：本发明涉及用于包装眼科装置的溶液，其包含至少一种抗微生物金属盐，其在高压灭菌和储存期间防止所述抗微生物金属盐的损失。

9. 发明公开

EP0923947A4 ONE-PACK PREPARATION FOR DISINFECTION, NEUTRALIZATION AND CLEANING OF CONTACT LENSES AND METHOD OF DISINFECTION, NEUTRALIZATION AND CLEANING 失效
标题翻译：成分组成进行消毒，消毒，中和，中和清洗和隐形眼镜清洁和方法
公开(公告)号：EP0923947A4
公开(公告)日：2001-06-13
申请号：EP97914593
申请日：1997-04-03
申请人： OPHTECS CORP
发明人： YONEDA TOYOAKI , FUJII TAKASHI , MORITA MIKA , OHNUMA TAKESHI , TANOUCHI HIROSHI , NAKAMURA SHIGERU
IPC分类号： A61L2/16 , A61L12/08 , A61L12/10 , C11D3/00 , C11D3/22 , C11D3/386 , C11D3/48 , C12S9/00 , G02C13/00
CPC分类号： C11D3/485 , A61L12/082 , A61L12/105 , C11D3/0042 , C11D3/0078 , C11D3/222 , C11D3/38618 , Y10S134/901 , Y10S514/84
摘要： A preparation for simultaneously conducting disinfection, neutralization and cleaning of soft contact lenses, and a method for using easily, efficiently, and safely the preparation. The preparation comprises a combination of a first preparation containing an iodine disinfectant and a protease with a second preparation containing a reducing agent and a foaming agent and having a coating for delayed release, and a nonionic surfactant is contained in at least one of the first and second preparations. Soiled soft contact lenses are kept in an aqueous solution yellowed or browned with iodine molecules, and, after the aqueous solution has become substantially colorless, the lenses are separated from the aqueous solution, thus facilitating a series of procedures, that is, disinfection, neutralization, and cleaning.

10. 发明公开

EP2526974A1 NUCLEATED TABLET FOR CONTACT LENS CLEANING, CONTACT LENS CLEANING PREPARATION CONTAINING SAME, AND METHOD FOR CLEANING CONTACT LENS 审中-公开
标题翻译：用于清洁隐形眼镜，研制核平板，以用于清除清洁隐形眼镜隐形眼镜和方法
公开(公告)号：EP2526974A1
公开(公告)日：2012-11-28
申请号：EP11732816.1
申请日：2011-01-14
申请人： Ophtecs Corporation
发明人： SASANUMA, Kazuhiro , TONE, Kazuhiro
IPC分类号： A61L2/16 , A01N25/02 , A01N25/34 , A01N59/12 , C11D1/722 , C11D3/10 , C11D3/20 , C11D3/48 , C11D7/04 , C11D7/12 , C11D7/26 , C11D17/00 , C11D17/06 , G02C13/00
CPC分类号： A61L12/082 , A01N25/34 , A61L12/105 , C11D3/0042 , C11D3/0052 , C11D3/0078 , C11D3/046 , C11D3/10 , C11D3/2086 , C11D3/3707 , C11D3/485 , C11D17/0039 , C11D17/0078 , A01N59/12
摘要： An object of the present invention is to provide a nucleated tablet for contact lens (CL) cleaning that makes it possible to disinfect a CL simply and easily in the presence of a foaming component; a CL cleaning preparation that contains the nucleated tablet; and a method for cleaning a CL. The nucleated tablet for CL cleaning of the invention is a nucleated tablet including an outer shell that contains iodine-based bactericide, a carbonate, an organic acid, and a surfactant having, per partial weight of 2000 out of the molecular weight thereof, less than one hydroxyl group, and an inner nucleus that contains a neutralizing agent, a carbonate, an organic acid, and a surfactant, wherein the inner nucleus is coated for extended release.
摘要翻译：本发明的一个目的是提供一种用于接触透镜（CL）清洗有核药片做使得有可能在发泡成分的存在下简单而容易地消毒一个CL; 清洁准备做CL包含核平板电脑; 和用于清洁CL的方法。对于本发明的CL清洗有核片剂是有核片剂包含在外壳也包含基于碘的杀菌剂，碳酸盐，有机酸，和具有表面活性剂，由2000部分的重量出分子量物，小于一个羟基基团，和表面活性剂到内核确实包含中和剂，碳酸盐，有机酸，和a，worin内核涂覆用于延长释放。

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