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1. 发明公开

EP4374912A3 METHOD TO INDUCE EXFOLIATION OF CELLS AND/OR TISSUE FRAGMENTS FOR ENHANCED CYTOPATHOLOGIC CELL COLLECTION 审中-实审
公开(公告)号：EP4374912A3
公开(公告)日：2024-09-25
申请号：EP24159974.5
申请日：2019-03-25
申请人： Adenocyte Ltd.
发明人： RUTENBERG, Mark , ADAM, Dan , LOEB, Emmanuel
IPC分类号： A61B8/00 , A61B8/08 , A61K49/22 , A61K47/00 , A61B10/00 , A61B10/02 , A61N7/00 , A61N7/02 , A61P1/18 , A61P35/00
CPC分类号： A61B8/08 , A61B8/481 , A61B8/0841 , A61B8/085 , A61N7/00 , A61B8/0825 , A61N2007/007320130101 , A61N2007/007820130101 , A61N7/02 , A61N2007/009520130101 , A61B2010/006120130101 , A61B10/0045 , A61B10/02 , A61K49/223 , A61P35/00 , A61P1/18
摘要： Methods and techniques for obtaining enriched cell samples from an organ in a subject using an ultrasound contrast agent and insonating. Contiguous fragments of epithelia are obtained which are useful for subsequent histological analysis and for informing therapy and other medical considerations.

2. 发明公开

EP4424243A1 DEVICE AND METHOD FOR COLLECTING AND CLEANING SOLID SUBSTANCES 审中-公开
公开(公告)号：EP4424243A1
公开(公告)日：2024-09-04
申请号：EP23158915.1
申请日：2023-02-28
申请人： Stichting IMEC Nederland
发明人： Schoeman, Rogier , Mc Sharry, Neil
IPC分类号： A61B10/00 , A61B10/04
CPC分类号： A61B10/0038 , A61B10/0045 , A61B2010/006120130101 , A61B10/04
摘要： A device (100) is provided for cleaning dirt particles from a solid body. The device comprises a driving shaft (110) configured to rotate along a rotational direction, and a container arrangement (150) comprising a first slotted container (160), and a second slotted container (170) attached to the first slotted container (160) and further to the driving shaft (110) via a fitting arrangement (180). In this regard, the fitting arrangement (180) is configured to simultaneously rotate the second slotted container (170) within the first slotted container (160) in a direction opposite to the rotational direction of the driving shaft (110) .

3. 发明公开

EP4374888A3 A CASSETTE CONFIGURED FOR USE WITH A MEDICAL WASTE COLLECTION SYSTEM 审中-实审
公开(公告)号：EP4374888A3
公开(公告)日：2024-08-28
申请号：EP24169234.2
申请日：2012-12-13
申请人： Stryker Corporation
发明人： VANDERWOUDE, Brian , DRAKE, Chad , HERSHBERGER, David , ISHAM, Steve , MACLACHLAN, Brian , REASONER, Stephen , EDINGER, Benjamin
IPC分类号： A61B10/00 , A61B10/02 , A61M1/00 , A61M3/02
CPC分类号： A61M2205/1220130101 , A61B10/0096 , A61B10/02 , A61B2010/006120130101 , A61B10/0045 , A61M2205/58520130101 , A61M1/79 , A61M1/77 , A61M3/0201 , A61M1/72 , A61M2205/12520130101 , A61M2205/12820130101 , A61M2205/12120130101
摘要： A specimen collection assembly (1700, 2000, 2600) configured for use with a medical fluid collection system (30) is disclosed which includes a housing (1701, 2001) configured for removable attachment to the fluid collection system (30); a first fitting (1734, 2664) attached to the housing (1701, 2001) and shaped to receive a suction line (50) that extends from a medical/surgical site; an outlet opening (1770, 2606) provided in the housing (1701, 2001) and through which, in use, fluid drawn through the first fitting (1734, 2664) flows through the housing (1701, 2001) and into the fluid collection system (30); and a porous screen (1890, 1914, 2741) configured to be disposed in the housing (1701, 2001) between the first fitting (1734, 2664) and the outlet opening (1770, 2606) for trapping material entrained in the fluid flow through the housing (1701, 2001). A supplemental opening (1729, 2030) is provided in the housing (1701, 2001), wherein the supplemental opening (1729, 2020) is separate from the outlet opening (1770, 2606) and opens into a first void space (1727, 2652) internal to the housing (1701, 2001). The first fitting (1734, 2664) opens into the first void space (1727, 2652) and there is a fluid path from the first void space (1727, 2652) to the housing outlet opening (1770, 2606). A first cap (1900, 1850, 2702) is configured for removable attachment to the housing (1701) so as to seat over the supplemental opening (1729, 2030), wherein the first cap (1900, 1850, 2702) has the porous screen (1890, 1914, 2741) shaped to occupy the first void space (1727, 2652, 2027) so that, when the first cap (1900, 1850, 2702) is disposed over the supplemental opening (1729, 2030) and in use, fluid that flows from the first fitting (1734) through the first void space (1727, 2652) to the outlet opening (1770, 2606) flows across the porous screen (1890, 1914, 2741). A second cap (1862, 1741) is configured for removable attachment to the housing (1701, 2001) so as to seat over the supplemental opening (1729, 2030), wherein the second cap (1862, 1741) does not have a screen so that, when the second cap (1862, 1741) is seated over the supplemental opening (1729, 2030) and in use, fluid that flows from the first fitting (1734) through the first void space (1727, 2652) is not filtered in the first void space (1727, 2652). A second fitting (1732, 2616) is attached to the housing (1701, 2001) and is shaped to receive a suction line, wherein the second fitting (1732, 2616) opens into a space (1704, 2604) in the housing (1701, 2001) other than the first void space (1727, 2652) and is in fluid communication with the outlet opening (1770, 2606).

4. 发明授权

EP3833268B1 INGESTIBLE APPARATUS FOR COLLECTING SAMPLES IN THE GASTROINTESTINAL TRACT AND/OR DELIVERING HEALTH-RELATED SUBSTANCE THERETO 有权
公开(公告)号：EP3833268B1
公开(公告)日：2024-09-25
申请号：EP19847562.6
申请日：2019-08-02
IPC分类号： A61B10/00 , A61B5/07 , A61B10/04 , A61B10/02 , A61M31/00
CPC分类号： A61B10/0045 , A61B2010/006120130101 , A61M31/002 , A61B10/04 , A61B2010/021620130101 , A61B10/02

5. 发明公开

EP4327754A3 SAMPLING CAPSULE SYSTEM AND METHODS 审中-实审
公开(公告)号：EP4327754A3
公开(公告)日：2024-04-24
申请号：EP23192830.0
申请日：2023-08-22
申请人： Jones, James Phillip
发明人： Jones, James Phillip
IPC分类号： A61B10/00
CPC分类号： A61B10/0038 , A61B10/0045 , A61B2010/006120130101
摘要： A non-invasive system for sampling gastrointestinal microbiota with their associated environment for discovery, characterization, medical research, diagnostics, and treatment using an ingestible, non-digestible sampling capsule. The capsule device, with ports open for acquiring a sample of gastrointestinal microbiota and content, is placed inside an immediate or delayed release capsule. When the outer capsule dissolves according to its specifications, enteric fluid and content enters the sampling capsule through the ports triggering a hydrophilic stop to release a pulling force to close the ports by enveloping the capsule outer casing over the inner casing, capturing the sample, and holding it sealed until it completes passage through the digestive track, and is recovered from feces for analysis.

6. 发明授权

EP3720425B1 SAMPLING CAPSULE SYSTEM 有权
公开(公告)号：EP3720425B1
公开(公告)日：2024-04-17
申请号：EP18884957.4
申请日：2018-12-05
IPC分类号： A61B10/00
CPC分类号： A61B2010/006120130101 , A61B10/0045

7. 发明公开

EP4410832A2 TREATMENT OF A DISEASE OF THE GASTROINTESTINAL TRACT WITH A TNF INHIBITOR 审中-实审
公开(公告)号：EP4410832A2
公开(公告)日：2024-08-07
申请号：EP24180290.9
申请日：2017-12-14
申请人： Biora Therapeutics, Inc.
发明人： JONES, Mitchell Lawrence , SINGH, Sharat , WAHL, Christopher Loren , STYLLI, Harry
IPC分类号： C07K16/24
CPC分类号： A61B5/6861 , A61B5/0075 , A61B5/01 , A61B5/024 , A61B5/0538 , A61B5/06 , A61B5/062 , A61B5/066 , A61B5/073 , A61B5/14539 , A61B5/14546 , A61B5/1459 , A61B5/42 , A61B5/4839 , A61M31/002 , C07K16/241 , C07K16/244 , A61K2039/54220130101 , A61P1/00 , A61P1/04 , A61B2010/006120130101
摘要： This disclosure features methods and compositions for treating diseases of the gastrointestinal tract with a TNF inhibitor.

8. 发明公开

EP4403114A2 SAMPLING CAPSULE SYSTEM 审中-实审
公开(公告)号：EP4403114A2
公开(公告)日：2024-07-24
申请号：EP24167966.1
申请日：2018-12-05
申请人： Jones, James Phillip
发明人： Jones, James Phillip
IPC分类号： A61B10/00
CPC分类号： A61B2010/006120130101 , A61B10/0045
摘要： A non-invasive system for sampling gastrointestinal microbiota with their associated environment for discovery, characterization, medical research, diagnostics, and treatment using an ingestible, non-digestible sampling capsule. The capsule device, with ports open for acquiring a sample of gastrointestinal microbiota and content, is placed inside an immediate or delayed release capsule. When the outer capsule dissolves according to its specifications, enteric fluid and content enters the sampling capsule through the ports triggering a hydrophilic stop to release a pulling force to close the ports by enveloping the capsule outer casing over the inner casing, capturing the sample, and holding it sealed until it completes passage through the digestive track, and is recovered from feces for analysis.

9. 发明公开

EP4378516A1 INGESTIBLE DEVICE AND METHOD FOR SAMPLING MATERIAL AND DELIVERING DRUG 审中-公开
公开(公告)号：EP4378516A1
公开(公告)日：2024-06-05
申请号：EP22210517.3
申请日：2022-11-30
申请人： Stichting IMEC Nederland
发明人： SCHOEMAN, Rogier
IPC分类号： A61M31/00 , A61B10/00
CPC分类号： A61B2010/006120130101 , A61B10/0045 , A61M31/002
摘要： An ingestible device (10) for sampling material at least one time is provided. The ingestible device (10) comprises a first chamber (11) being enlargeable in space, comprising an inlet (6), and to be filled with the material to be sampled, a second chamber (12) comprising a toroidal reservoir (2) being diminishable in space, to be filled with liquid to be delivered, and an actuating mechanism. In this context, the actuating mechanism is configured such that triggering the actuating mechanism leads to deflate the toroidal reservoir (2) so that the first chamber (11) enlarges to collect the material to be sampled through the inlet (6) and the second chamber (12) diminishes to release the liquid through at least one outlet of the toroidal reservoir (2).

10. 发明公开

EP4374912A2 METHOD TO INDUCE EXFOLIATION OF CELLS AND/OR TISSUE FRAGMENTS FOR ENHANCED CYTOPATHOLOGIC CELL COLLECTION 审中-实审
公开(公告)号：EP4374912A2
公开(公告)日：2024-05-29
申请号：EP24159974.5
申请日：2019-03-25
申请人： Adenocyte Ltd.
发明人： RUTENBERG, Mark , ADAM, Dan , LOEB, Emmanuel
IPC分类号： A61N7/02
CPC分类号： A61B8/08 , A61B8/481 , A61B8/0841 , A61B8/085 , A61N7/00 , A61B8/0825 , A61N2007/007320130101 , A61N2007/007820130101 , A61N7/02 , A61N2007/009520130101 , A61B2010/006120130101 , A61B10/0045 , A61B10/02 , A61K49/223 , A61P35/00 , A61P1/18
摘要： Methods and techniques for obtaining enriched cell samples from an organ in a subject using an ultrasound contrast agent and insonating. Contiguous fragments of epithelia are obtained which are useful for subsequent histological analysis and for informing therapy and other medical considerations.

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