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1. 发明专利

DE3639082C2 未知
公开(公告)号：DE3639082C2
公开(公告)日：1988-09-22
申请号：DE3639082
申请日：1986-11-14
申请人： UNIVERSITY OF GUELPH, GUELPH, ONTARIO, CA
发明人： BEVERSDORF, WALLACE D., GUELPH, ONTARIO, CA , ERICKSON, LAWRENCE R., MISSISSAGUA, ONTARIO, CA , GRANT, IAN, GUELPH, ONTARIO, CA
IPC分类号： A01H1/02 , A01N25/00
摘要： The process of the present invention provides a convenient route for producing a predetermined hybrid variety of a crop which is capable of undergoing both self-pollination and cross-pollination. Cytoplasmic male sterile plants which also exhibit herbicide tolerance attributable solely to nuclear genes are the key plants for use in the present process. Economical bulk planting of the key plants with either maintainer or restorer plants is made possible. Following cross-pollination from a pollen source which lacks the herbicide tolerance unneeded plants effectively are eliminated by use of a herbicide. For instance, unwanted plants may be effectively eliminated immediately after pollination or prior to pollination in the succeeding generation (provided the requisite genes for herbicide tolerance are present therein) to make possible the existence in an unharmed state of a substantially homogeneous stand of the desired plants. In a preferred embodiment cytoplasmic male sterile plants, plants resulting from the self-pollination of a maintainer, and restorer plants are planted in a substantially random population prior to the application of two different herbicides (as defined) at the appropriate times. The process of the present invention is applicable to grain crops, forage crops, seed-propagated fruits, seed-propagated ornamentals, and industrial species. In a particularly preferred embodiment a predetermined variety of Brassica napus (i.e., rape or improved forms thereof known as canola) is formed which is the product of cross-pollination.

2. 发明专利

DE3638864C2 未知
公开(公告)号：DE3638864C2
公开(公告)日：1988-09-08
申请号：DE3638864
申请日：1986-11-14
申请人： UNIVERSITY OF GUELPH, GUELPH, ONTARIO, CA
发明人： BEVERSDORF, WALLACE D., GUELPH, ONTARIO, CA , ERICKSON, LAWRENCE R., MISSISSAUGA, ONTARIO, CA , GRANT, IAN, GUELPH, ONTARIO, CA
IPC分类号： A01H1/02 , A01N25/00
摘要： The process of the present invention provides a convenient route for producing a predetermined hybrid variety of a crop which is capable of undergoing both self-pollination and cross-pollination. Cytoplasmic male sterile plants which also exhibit cytoplasmic herbicide tolerance (i.e., to a Type A herbicide) and tolerance to a different herbicide attributable solely to nuclear genes (i.e., to a Type B herbicide) are the key plants for use in the present process. The maintainer and restorer plants exhibit tolerance to different herbicides (i.e., to either a Type A herbicide or a Type B herbicide). The economical bulk planting of the parent plants is made possible during each step of the process. For instance, cytoplasmic male sterile plants, plants resulting from the self-pollination of a maintainer, and restorer plants can be grown in a substantially random population, with the self-pollinated maintainer plants being destroyed by an appropriate herbicide prior to pollination, and the self-pollinated restorer plants being destroyed by an appropriate herbicide immediately following pollination or in the subsequent generation. The process of the present invention is applicable to grain crops, forage crops, seed-propagated fruits, seed-propagated ornamentals, and industrial species. In a particularly preferred embodiment a predetermined variety of Brassica napus (i.e., rape or improved forms thereof known as canola) is formed which is the product of cross-pollination.

3. 发明申请

WO2016138593A1 BIODEGRADABLE POLYMER-BASED BIOCOMPOSITES WITH TAILORED PROPERTIES AND METHOD OF MAKING THOSE 审中-公开
标题翻译：具有定性特性的可生物降解的基于聚合物的生物聚合物及其制备方法
公开(公告)号：WO2016138593A1
公开(公告)日：2016-09-09
申请号：PCT/CA2016/050237
申请日：2016-03-04
申请人： UNIVERSITY OF GUELPH
发明人： MOHANTY, Amar Kumar , MISRA, Manjusri , ZARRINBAKHSH, Nima , MUTHURAJ, Rajendran , WANG, Tao , RODRIGUEZ, Arturo , VIVEKANANDHAN, Singaravelu
IPC分类号： C08L101/16 , C08J3/20 , C08K11/00 , C08K3/00 , C08L101/06 , C08L67/00
CPC分类号： C08J3/201 , C08J5/045 , C08J2300/16 , C08J2367/02 , C08J2367/04 , C08J2467/02 , C08J2467/04 , C08K3/013 , C08K5/0016 , C08K5/103 , C08K11/00 , C08K11/005 , C08L67/00 , C08L101/06 , C08L101/16 , C08L2201/06 , C08L67/04 , C08L67/02
摘要： A biodegradable composite including: (a) a polymeric matrix having a biodegradable polymer; (b) a filler; and (c) an anhydride grafted compatibilizer including one or more biodegradable polymers modified with an anhydride group. The composite may also include (d) polymer additives such as polymer chain extenders or plasticizers. An in situ method of manufacturing the biodegradable composite of the present invention, including the steps of: (a) melting one or more biodegradable polymers in the presence of a functional monomer and a free radical initiator to form a mixture; and (b) adding a filler and polymer additives to the mixture thereby manufacturing the biodegradable composite. A method of manufacturing a biodegradable polymer including (a) synthesizing a compatibilizer by (i) mixing a free radical initiator and a functional monomer, (ii) melting one or more biodegradable polymers to form a melt, and (iii) combining the product of step (i) and the melt of step (ii) thereby synthesizing the compatibilizer; and (b) mixing the compatibilizer of step (a), with a matrix of one or more biodegradable polymers and a filler and polymer additives, thereby manufacturing the biodegradable or compostable composite.
摘要翻译：一种可生物降解的复合材料，包括：（a）具有可生物降解的聚合物的聚合物基质; （b）填料; 和（c）包含用酸酐基改性的一种或多种可生物降解聚合物的酸酐接枝增容剂。复合材料还可以包括（d）聚合物添加剂，例如聚合物增链剂或增塑剂。本发明的生物可降解复合材料的原位制备方法，包括以下步骤：（a）在功能单体和自由基引发剂存在下熔融一种或多种可生物降解的聚合物以形成混合物; 和（b）向混合物中加入填料和聚合物添加剂，从而制造可生物降解的复合材料。一种制造生物可降解聚合物的方法，包括（a）通过（i）混合自由基引发剂和官能单体合成增容剂，（ii）将一种或多种可生物降解的聚合物熔融以形成熔体，和（iii）将步骤（i）和步骤（ii）的熔体，从而合成增容剂; 和（b）将步骤（a）的增容剂与一种或多种可生物降解聚合物的基质和填料和聚合物添加剂混合，从而制造可生物降解的或可堆肥的复合材料。

4. 发明申请

WO2015135080A1 RENEWABLE REPLACEMENTS FOR CARBON BLACK IN COMPOSITES AND METHODS OF MAKING AND USING THEREOF 审中-公开
标题翻译：复合材料中碳黑的可再生替代方法及其制备及其使用方法
公开(公告)号：WO2015135080A1
公开(公告)日：2015-09-17
申请号：PCT/CA2015/050189
申请日：2015-03-13
申请人： UNIVERSITY OF GUELPH
发明人： MOHANTY, Amar , MISRA, Manjusri , BALI, Atul , RODRIGUEZ-URIBE, Arturo
IPC分类号： C08J3/22 , B09B3/00 , C08K3/04 , C08L101/00
CPC分类号： C08J3/226 , B09B3/00 , B09B3/0083 , C08J2323/06 , C08J2323/12 , C08J2327/06 , C08J2400/16 , C08J2423/06 , C08J2423/12 , C08J2427/06 , C08K3/04 , C08L23/06 , C08L23/12 , C08L27/06 , C08L101/00 , C08L2310/00 , Y02W30/20
摘要： Biocarbon is presented as an alternative to synthetic carbon black. Master batches having biocarbon for usage in raw plastics and/or the production of composites. Biocarbon is mainly derived from plant biomass, but other sources can be used. A method of producing the master batch: (a) pyrolyzing processed biomass in an oxygen-starved environment to produced biocarbon; (b) comminuting the biocarbon in a reduced oxygen atmosphere; (c) cooling the comminuted biocarbon; (d) mixing the cooled comminuted biocarbon with a carrier resin, thereby producing the master batch.
摘要翻译：生物碳被认为是合成炭黑的替代品。具有生物碳的主批次用于原始塑料和/或复合材料的生产。生物碳主要来自植物生物量，但可以使用其他来源。一种生产母料的方法：（a）将氧化饥饿的环境中加工的生物质热解生成生物碳; （b）在还原氧气氛中粉碎生物碳; （c）冷却粉碎的生物碳; （d）将冷却的粉碎生物碳与载体树脂混合，从而制备母料。

5. 发明申请

WO2015106342A1 COMPOSITIONS AND METHODS TO ENCAPSULATE AND CONTROL RELEASE OF VOLATILE ORGANIC COMPOUNDS FOR INCREASING SHELF-LIFE OF PERISHABLE PRODUCTS 审中-公开
标题翻译：用于增加和控制挥发性有机化合物释放的组合物和方法，以增加可持续产品的使用寿命
公开(公告)号：WO2015106342A1
公开(公告)日：2015-07-23
申请号：PCT/CA2015/000027
申请日：2015-01-15
申请人： UNIVERSITY OF GUELPH
发明人： LIM, Loong-Tak , MIHINDUKULASURIYA, Suramya D.F. , PALIYATH, Gopinadhan , SUBRAMANIAN, Jayasankar , SULLIVAN, J. Alan
IPC分类号： A23L3/3499 , A01N25/10 , A01N35/02 , A23B7/154 , A23L3/3463 , A23P1/04 , B01J13/00 , C08J3/20
CPC分类号： A01N3/00 , A01N25/10 , A01N25/28 , A01N25/34 , A23B7/154 , A23L3/3499 , A23N15/06 , A23V2002/00 , B05D1/12 , D01D5/003 , D01D5/04 , D01D5/0985 , D01D11/00 , D01F1/10 , D01F2/00 , D01F6/44 , D01F6/88 , D01F6/96 , D01F9/00 , A01N35/02
摘要： The invention provides methods for the encapsulation of volatile organic compounds by formation of stable emulsions of the volatile organic compound that are mixed with encapsulating polymer solutions and then formed into ultrafine fibers. The ultrafine fibers containing the encapsulated volatile organic compounds can be formed into a variety of formats for use to preserve perishable products.
摘要翻译：本发明提供了通过形成与包封聚合物溶液混合然后形成超细纤维的挥发性有机化合物的稳定乳液来包封挥发性有机化合物的方法。含有包封的挥发性有机化合物的超细纤维可以形成用于保存易腐产品的各种形式。

6. 发明申请

WO2015042704A1 BIOMARKERS FOR MYCOBACTERIUM AVIUM PARATUBERCULOSIS (MAP) 审中-公开
标题翻译：生物标记物（MYCOBACTERIUM AVIUM PARATUBERCULOSIS）（MAP）
公开(公告)号：WO2015042704A1
公开(公告)日：2015-04-02
申请号：PCT/CA2014/050914
申请日：2014-09-24
申请人： UNIVERSITY OF GUELPH
发明人： MUTHARIA, Lucy M. , FACCIUOLO, Antonio
IPC分类号： C07K14/35 , A61K39/04 , A61P31/04 , A61P37/04 , C07K16/12 , C12P21/02 , G01N33/569
CPC分类号： C07K14/35 , A61K39/04 , C07K16/1289 , C07K2317/33 , G01N33/5695 , G01N2333/35 , G01N2469/20
摘要： Described are methods and products useful for identifying subjects with Mycobacterium avium subspecies paratuberculosis (MAP). A number of protein antigens secreted into culture filtrate by MAP are identified and binding proteins selective for these antigens are demonstrated to be useful for detecting subjects with MAP infections including subjects with Johne's disease.
摘要翻译：描述了用于鉴定具有分枝杆菌亚种副结核病（MAP）的受试者的方法和产品。鉴定了通过MAP分泌到培养物滤液中的许多蛋白质抗原，对这些抗原选择性的结合蛋白被证明可用于检测MAP感染的受试者，包括具有约翰氏病的受试者。

7. 发明申请

WO2013016812A1 NOVEL 1,3-DIACYLGLYCEROL (1,3-DAG) FOR HARD FAT APPLICATIONS 审中-公开
标题翻译：新型1,3-二氨基甘油（1,3-DAG）用于硬脂酸应用
公开(公告)号：WO2013016812A1
公开(公告)日：2013-02-07
申请号：PCT/CA2012/000732
申请日：2012-08-02
申请人： CRAVEN, Richard John , LENCKI, Robert , UNIVERSITY OF GUELPH
发明人： CRAVEN, Richard John , LENCKI, Robert
IPC分类号： A23D7/01 , A23G1/38 , C07C69/593 , C11B3/00 , C11C3/00
CPC分类号： A23G3/40 , A23D9/02 , A23G1/38 , C07C67/14 , C07C67/52 , C11B1/00 , C11B1/025 , C07C69/58
摘要： The invention provides 1,3-DAGs with melting point ranges of from about 32°C to about 37°C for use in a variety of hard fat applications and in particular for the preparation of a cocoa butter substitute for confectionery use. The invention contemplates novel 1,3-DAGs, cocoa butter substitute incorporating such 1,3-DAG compounds, confectionery products and shortenings containing both and lastly methods of making such.
摘要翻译：本发明提供熔点范围为约32℃至约37℃的1,3-DAG，用于各种硬脂肪应用中，特别是制备用于糖果使用的可可脂替代物。本发明考虑了新颖的1,3-DAG，可可脂替代物掺入这种1,3-DAG化合物，糖果产品和起酥油，其中包含最后的制备方法。

8. 发明申请

WO2010063113A1 ANTI-COBRA TOXIN ANTIBODY FRAGMENTS AND METHOD OF PRODUCING A VHH LIBRARY 审中-公开
标题翻译：抗COBRA毒素抗体片段和生产VHH文库的方法
公开(公告)号：WO2010063113A1
公开(公告)日：2010-06-10
申请号：PCT/CA2009/001760
申请日：2009-12-04
申请人： UNIVERSITY OF GUELPH , HALL, J., Christopher , RICHARD, Gabrielle , MCLEAN, Michael, D.
发明人： HALL, J., Christopher , RICHARD, Gabrielle , MCLEAN, Michael, D.
IPC分类号： C12N15/13 , A61K39/395 , A61P39/02 , C07K16/18 , C40B40/06
CPC分类号： C07K16/18 , A61K2039/505 , C07K2317/22 , C07K2317/56 , C07K2317/565 , C07K2317/569 , C07K2317/76 , C07K2317/92 , Y10S530/858
摘要： A method of constructing a V H H library from an immunized camelid, using whole venom or an extract thereof There is also provided V H H antibody fragments isolated from a library produced in hyperimmunized llama These V H H antibody fragments were sequenced, and specifically bind α-cobratoxin.
摘要翻译：使用全毒液或其提取物从免疫的骆驼构建VHH文库的方法还提供了从超免疫化的美洲驼中产生的文库分离的VHH抗体片段。对这些VHH抗体片段进行测序，并特异性结合α-干酪氨酸激酶。

9. 发明申请

WO2009081287A3 POLYSACCHARIDE NANOPARTICLES 审中-公开
公开(公告)号：WO2009081287A3
公开(公告)日：2009-07-02
申请号：PCT/IB2008/003958
申请日：2008-12-19
申请人： UNIVERSITY OF GUELPH , DUTCHER, John, Robert , BEVERIDGE, Terry, J. , KORENEVSKI, Anton , STUKALOV, Oleg , PAPP-SZABO, Erzsebet
发明人： DUTCHER, John, Robert , BEVERIDGE, Terry, J. , KORENEVSKI, Anton , STUKALOV, Oleg , PAPP-SZABO, Erzsebet
IPC分类号： C08L5/00 , A61K47/36 , A61K47/48 , A61K8/73 , A61K9/14 , C12P19/04 , A61K49/00
摘要： Polysaccharide nanoparticles that are particularly useful in for example drug and agent delivery, tissue-specific targeting, for medical imaging and diagnosis, as well as modifiers of physico-chemical properties. The nanoparticles can be highly-branched glucose homopolymers and can be characterized by a uniform spherical shape. They are monodisperse, hydrophilic and produce low solution viscosities. The nanoparticles are non¬ toxic, biocompatible and biodegradable. Also, the process of isolation of said polysaccharide nanoparticles from various organisms including, but not limited to, microorganisms such as bacteria and yeasts. Also provided are methods for chemical conjugation of the polysaccharide nanoparticles with various agents. Also provided are examples of use of the polysaccharide nanoparticles and their derivatives as drug delivery systems and fluorescent diagnostics.

10. 发明申请

WO2006097787A1 BOVINE CAST GENE SNP AND MEAT TENDERNESS 审中-公开
标题翻译：牛肝癌基因SNP和肉类TenderNess
公开(公告)号：WO2006097787A1
公开(公告)日：2006-09-21
申请号：PCT/IB2005/002983
申请日：2005-07-18
申请人： UNIVERSITY OF GUELPH , SCHENKEL, Flavio, Schramm , MILLER, Stephen, Paul , JIANG, Zhihua
发明人： SCHENKEL, Flavio, Schramm , MILLER, Stephen, Paul , JIANG, Zhihua
IPC分类号： C07H21/00 , G06Q50/00 , G06F19/00 , C12Q1/68 , C12N15/11
CPC分类号： C12Q1/6888 , C12Q2600/156
摘要： The present invention relates to the identification of a single nucleotide polymorphism (SNP) within the bovine CAST locus encoding the calpastatin protein, wherein the allelic variation of the SNP is a G/C transversion associated with post-mortem muscle tenderness. The invention further relates to oligonucleotides useful in identifying the genotype of bovines as it relates to the CAST locus polymorphic site. The invention also encompasses computerassisted methods and systems for improving the production efficiency for livestock having marketably tender meat using multiple data, and in particular the genotype of the animals as it relates to the CAST SNP. These methods of the invention encompass obtaining a genetic sample from each animal in a herd of livestock, determining the genotype of each animal with respect to specific quality traits as defined by a panel of at least two single polynucleotide polymorphisms (SNPs), one SNP corresponding to a site between exons 5 and 6 of the bovine CAST locus, grouping animals with like genotypes, and optionally, further sub-grouping animals based on like phenotypes.
摘要翻译：本发明涉及编码钙蛋白酶抑制蛋白的牛CAST基因座中单核苷酸多态性（SNP）的鉴定，其中SNP的等位基因变异是与死后肌肉触痛相关的G / C逆转。本发明还涉及可用于鉴定与CAST基因座多态性位点相关的牛的基因型的寡核苷酸。本发明还包括使用多种数据，特别是与CAST SNP相关的动物的基因型，来提高具有市场上嫩的肉类的家畜的生产效率的计算机辅助方法和系统。本发明的这些方法包括从家畜群体中的每只动物获得遗传样品，根据由至少两个单个多核苷酸多态性（SNP）的一组确定的特定质量性状确定每只动物的基因型，一个SNP对应到牛CASTlocus的外显子5和6之间的位点，分组具有相似基因型的动物，以及任选地，基于类似表型进一步分组动物。

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