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    • 6. 发明申请
    • PROCESS FOR PRODUCING SUGAR CHAIN ASPARAGINE DERIVATIVE
    • 生产糖链脂肪酸衍生物的方法
    • WO2004070046A8
    • 2005-08-25
    • PCT/JP2004001048
    • 2004-02-03
    • OTSUKA CHEMICAL CO LTDFUKAE KAZUHIRO
    • FUKAE KAZUHIRO
    • C12P19/28C08B37/00
    • C12P19/28
    • A process for producing sugar chain asparagine derivatives from defatted egg yolk, which comprises: (a) a step in which defatted egg yolk is treated with a proteinase to produce a sugar chain peptide mixture; (b) a step in which the sugar chain peptide mixture is treated with a peptidase to produce a sugar chain asparagine mixture; (c) a step in which a lipid-soluble protective group is introduced into sugar chain asparagines in the sugar chain asparagine mixture to produce a sugar chain asparagine derivative mixture; and (d) a step in which the sugar chain asparagine derivative mixture is subjected to chromatography to separate it into sugar chain asparagine derivatives.
    • 一种从脱脂蛋黄制备糖链天冬酰胺衍生物的方法,其包括:(a)将脱脂蛋黄用蛋白酶处理以产生糖链肽混合物的步骤; (b)将糖链肽混合物用肽酶处理以产生糖链天冬酰胺混合物的步骤; (c)在糖链天冬酰胺混合物中的糖链天冬酰胺中引入脂溶性保护基以产生糖链天冬酰胺衍生物混合物的步骤; 和(d)将糖链天冬酰胺衍生物混合物进行色谱法分离成糖链天冬酰胺衍生物的步骤。