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1. 发明专利

TW200628178A 用於促進以受控方式將流體釋放至周遭環境中之使用流體產生單元的裝置 DEVICE EMPLOYING GAS GENERATING CELL FOR FACILITATING CONTROLLED RELEASE OF FLUID INTO AMBIENT ENVIRONMENT 审中-公开
简体标题：用于促进以受控方式将流体释放至周遭环境中之使用流体产生单元的设备 DEVICE EMPLOYING GAS GENERATING CELL FOR FACILITATING CONTROLLED RELEASE OF FLUID INTO AMBIENT ENVIRONMENT
公开(公告)号：TW200628178A
公开(公告)日：2006-08-16
申请号：TW094122360
申请日：2005-07-01
申请人：麥克羅林公司 MICROLIN, L.C.
发明人：圖曼沃德 WOLD, TRUMAN , 約翰J 麥克艾沃伊 MCEVOY, JOHN J. , 肯尼士J 慕德拉克 MUDERLAK, KENNETH J. , 陶德J 慕德拉克 MUDERLAK, TODD J. , 大衛楚亞 CHUAH, DAVID , 席恩貝林格 BELLINGER, SEAN
IPC分类号： A61L
CPC分类号： A61L9/037 , A61L9/122 , A61L9/127
摘要：一種用於以可控制之方式將流體釋放至周遭環境中的裝置。依照本發明之一特定實施例，此裝置包含一個具有一流體隔室及一孔口隔室的外殼，孔口隔室被配置成鄰接該流體隔室，且經由一個孔口而與該流體隔室相連通。此流體隔室包含有用於釋放至周遭環境中之流體。當裝置處於未啟動狀態之中時，孔口隔室包括有一個被一可移除密封用元件蓋住的流體出口且包含有初始量的流體。一個流體限制器被配置成鄰接孔口，用以在未啟動狀態下限制流體從流體隔室流入孔口隔室。一個氣體產生單元係選擇性地與流體隔室相連通，使得當裝置在已作動之狀態下，氣體產生單元所生成的氣體能夠被導引至流體隔室內。一個流體膜片被配置於氣體產生單元與流體隔室之間，使得在已啟動狀態下，容許氣體產生單元產生的氣體能夠通過而流入流體隔室，而在未啟動狀態下，防止位於流體容器內的流體通過進入氣體產生單元內。裝置的啟動係藉由移除密封用元件，以容許初始量的流體能夠經由流體出口而流出孔口隔室，並且啟動氣體產生單元來製造氣體，以及採用一可控制之方式，迫使流體從流體隔室進入孔口隔室及流出流體出口。
简体摘要：一种用于以可控制之方式将流体释放至周遭环境中的设备。依照本发明之一特定实施例，此设备包含一个具有一流体隔室及一孔口隔室的外壳，孔口隔室被配置成邻接该流体隔室，且经由一个孔口而与该流体隔室相连通。此流体隔室包含有用于释放至周遭环境中之流体。当设备处于未启动状态之中时，孔口隔室包括有一个被一可移除密封用组件盖住的流体出口且包含有初始量的流体。一个流体限制器被配置成邻接孔口，用以在未启动状态下限制流体从流体隔室流入孔口隔室。一个气体产生单元系选择性地与流体隔室相连通，使得当设备在已作动之状态下，气体产生单元所生成的气体能够被导引至流体隔室内。一个流体膜片被配置于气体产生单元与流体隔室之间，使得在已启动状态下，容许气体产生单元产生的气体能够通过而流入流体隔室，而在未启动状态下，防止位于流体容器内的流体通过进入气体产生单元内。设备的启动系借由移除密封用组件，以容许初始量的流体能够经由流体出口而流出孔口隔室，并且启动气体产生单元来制造气体，以及采用一可控制之方式，迫使流体从流体隔室进入孔口隔室及流出流体出口。

2. 发明申请

WO2005123153A2 DEVICE EMPLOYING GAS GENERATING CELL FOR FACILITATING CONTROLLED RELEASE OF FLUID INTO AMBIENT ENVIRONMENT 审中-公开
标题翻译：使用气体生成装置的装置，以便将流体控制释放到环境环境中
公开(公告)号：WO2005123153A2
公开(公告)日：2005-12-29
申请号：PCT/US2005/021022
申请日：2005-06-14
申请人： MICROLIN, L.C.
发明人： JOSHI, Ashok, V. , WOLD, Truman , McEVOY, John, J.
IPC分类号： A61L9/04
CPC分类号： A61L9/037 , A61L9/122 , A61L9/127
摘要： A device for controllably releasing a fluid into an ambient environment. According to a particular embodiment of the present invention, the device comprises a housing having a fluid compartment and an orifice compartment disposed adjacent thereto and in fluid communication therewith via an orifice. The fluid compartment contains the fluid for release to the ambient environment. The orifice compartment includes a fluid exit opening covered by a removable sealing element and contains an initial quantity of fluid when the device is in an inactivated state. A fluid restrictor is disposed adjacent the orifice to restrict fluid flow from the fluid compartment into the orifice compartment in the inactivated state. A gas-generating cell is in selective communication with the fluid compartment such that gas generated by the cell is directed into the fluid compartment when the device is in an activated state. A fluid membrane is disposed between the gas-generating cell and the fluid compartment that allows the gas generated by the cell to pass therethrough to the fluid compartment in the activated state while preventing fluid within the fluid container from passing therethrough to the cell in the inactivated state. The device is activated by removing the sealing element to allow the initial quantity of fluid to exit out of the orifice compartment via the fluid exit opening and activating the cell to generate gas and force fluid from the fluid compartment to the orifice compartment and out the fluid exit opening in a controlled manner.
摘要翻译：用于将流体可控地释放到周围环境中的装置。根据本发明的特定实施例，该装置包括具有流体隔室和邻近其设置并通过孔流体连通的孔室的壳体。流体室包含用于释放到周围环境的流体。孔室包括由可移除的密封元件覆盖的流体出口，并且当装置处于非活动状态时包含初始量的流体。流体限制器设置在孔口附近以限制处于非活动状态的流体从流体隔室流入孔室。气体发生电池与流体室选择性地连通，使得当该装置处于激活状态时，电池产生的气体被引导到流体室中。流体膜设置在气体发生池和流体隔室之间，其允许由活化的细胞产生的气体通过其流动到活化状态的流体隔室，同时防止流体容器内的流体通过其进入灭活的细胞州。该装置通过移除密封元件而被激活，以允许初始量的流体经由流体出口开口离开孔室，并激活电池以产生气体并迫使流体从流体隔室流到孔室并流出流体以受控的方式出口。

3. 发明申请

WO2005025447A2 DEVICE ΑΝD METHOD FOR WOUND THERAPY 审中-公开
标题翻译：装置治疗方法AlphaNuD
公开(公告)号：WO2005025447A2
公开(公告)日：2005-03-24
申请号：PCT/US2004/029184
申请日：2004-09-08
申请人： MICROLIN, L.C.
发明人： JOSHI, Ashok, V.
IPC分类号： A61F
CPC分类号： A61M1/0066 , A61M1/009 , A61M2202/0208
摘要： A disposable wound-healing device is disclosed that incorporates a housing having a fluid-impermeable material having a cavity and a perimeter that can be sealed in an air-tight manner over a wound region of a patient. The device is capable of producing a negative pressure over the wound region by either removing oxygen from within the cavity, or absorbing fluid into the cavity and then removing the fluid from the cavity. The oxygen may be removed via chemical absorption, by an electrochemical cell or by a chemical reaction that cannibalizes oxygen from the cavity. The fluid may be removed through the use of osmotic or electro osmotic cells, or through a one-way valve. The negative partial pressure over the wound region promotes healing.
摘要翻译：公开了一种一次性伤口愈合装置，其包括具有流体不可渗透材料的壳体，该壳体具有空腔和可以以气密方式密封在患者的伤口区域上的周边。该装置能够通过从空腔内去除氧气或将流体吸入空腔中并且然后从腔体去除流体而在伤口区域上产生负压。氧气可以通过化学吸收，电化学电池或通过使空气中的氧气分解的化学反应来除去。流体可以通过使用渗透或电渗透细胞或通过单向阀去除。伤口区域的负分压促进愈合。

4. 发明申请

WO2005005304A2 MOVING EMANATORS 审中-公开
标题翻译：移动电动机
公开(公告)号：WO2005005304A2
公开(公告)日：2005-01-20
申请号：PCT/US2004/020949
申请日：2004-06-30
申请人： MICROLIN, L.C.
发明人： JOSHI, Ashok, V. , DOMENICK, Lawrence
IPC分类号： B67D
CPC分类号： A61L9/145 , A01M1/2033 , A01M1/205 , A45D34/02 , A61L9/042 , A61L9/127
摘要： A controlled sustained release fluid delivery device is disclosed which has enhanced fluid delivery. The device generally includes a housing having a fluid reservoir therein for holding a fluid, at least one opening in the housing for enabling fluid delivery out of the fluid reservoir and the housing, and structures for delivering the fluid, and retaining the fluid proximate an ambient environment. Once held there, the structure holding the fluid is vibrated so as to enhance the delivery of the fluid to the ambient environment. Other aspects are also disclosed.
摘要翻译：公开了一种受控的持续释放流体输送装置，其具有增强的流体输送。该装置通常包括壳体，其中具有用于保持流体的流体储存器，壳体中的至少一个开口，用于使流体从流体储存器和壳体输出，以及用于输送流体的结构，以及将流体保持在邻近环境环境。一旦保持在那里，保持流体的结构被振动，以便增强流体到周围环境的输送。还公开了其他方面。

5. 发明申请

WO2005115356A2 ANTI-MICROBIAL HANDLE SYSTEM 审中-公开
标题翻译：抗微生物手柄系统
公开(公告)号：WO2005115356A2
公开(公告)日：2005-12-08
申请号：PCT/US2005/018500
申请日：2005-05-25
申请人： MICROLIN, L.C.
发明人： JOSHI, Ashok, V.
IPC分类号： A61K9/70
CPC分类号： A61L2/18 , A01N25/34 , A61L2/20 , A61L2/238 , E05B1/0069 , A01N59/00 , A01N59/16 , A01N59/20
摘要： An antimicrobial handle system comprising a handle and an antimicrobial component in communication with the handle to impart antimicrobial properties thereto. According to particular aspects of the invention, the antimicrobial component may be in the form of an antimicrobial material integrally formed with the handle; a handle portion made from an antimicrobial material and removably connected to the handle; an antimicrobial coating disposed on the handle; a film disposed on the handle; an ion generator arrangement in communication with the handle; a sterilizing gas generator in communication with the handle; a sterilizing corona generator in communication with the handle; an antimicrobial lightsource in communication with the handle; a fluid dispenser to dispense an antimicrobial fluid onto the handle; or a combination thereof. The antimicrobial component may include an active oxygen releasing material; an active ozone, UV light, Halide gas, silver ion, or Halide ion releasing material; an antimicrobial fluid; or a photoactive material that exhibits antimicrobial properties when exposed to a light source. Other antimicrobial components are also contemplated in accordance with the principles of the present invention.
摘要翻译：一种抗微生物手柄系统，包括手柄和与手柄连通的抗微生物组件以赋予其抗微生物性质。根据本发明的特定方面，抗微生物组分可以是与手柄一体形成的抗微生物材料的形式; 由抗微生物材料制成并可移除地连接到手柄的手柄部分; 设置在手柄上的抗菌涂层; 设在手柄上的胶片; 与手柄连通的离子发生器装置; 与手柄连通的消毒气体发生器; 与把手连通的消毒电晕发生器; 与手柄通信的抗菌光源; 流体分配器，用于将抗微生物流体分配到手柄上; 或其组合。抗微生物组分可以包括释放活性氧的物质; 活性臭氧，紫外光，卤化物气体，银离子或卤化物离子释放材料; 抗菌液体; 或当暴露于光源时具有抗微生物性质的光敏材料。根据本发明的原理，也考虑了其它抗微生物组分。

6. 发明申请

WO2005005051A2 MOVING EMANATORS 审中-公开
标题翻译：移动EMANATORS
公开(公告)号：WO2005005051A2
公开(公告)日：2005-01-20
申请号：PCT/US2004/021221
申请日：2004-06-30
申请人： MICROLIN, L.C.
发明人： JOSHI, Ashok, V. , DOMENICK, Lawrence
IPC分类号： B05B
CPC分类号： A61L9/145 , A01M1/2033 , A01M1/205 , A45D34/02 , A61L9/042 , A61L9/127
摘要： A controlled sustained release fluid delivery device is disclosed which has enhanced fluid delivery. The device generally includes a housing having a fluid reservoir therein for holding a fluid, at least one opening in the housing for enabling fluid delivery out of the fluid reservoir and the housing, and structures for delivering the fluid, and retaining the fluid proximate an ambient environment. Once held there, the structure holding the fluid is vibrated so as to enhance the delivery of the fluid to the ambient environment. Other aspects are also disclosed.
摘要翻译：公开了一种控制持续释放液输送装置，其具有增强的液体输送。该装置通常包括壳体，壳体中具有用于容纳流体的流体容器，用于使流体能够从流体容器和壳体输出的壳体中的至少一个开口，以及用于输送流体并且将流体保持在环境附近环境。一旦保持在那里，保持流体的结构就会振动，从而增强流体向周围环境的输送。其他方面也被公开。

7. 发明申请

WO2003092662A1 FLUID DELIVERY DEVICE HAVING AN ELECTROCHEMICAL PUMP WITH AN ANIONIC EXCHANGE MEMBRANE AND ASSOCIATED METHOD 审中-公开
标题翻译：具有阴离子交换膜的电化学泵和相关方法的流体输送装置
公开(公告)号：WO2003092662A1
公开(公告)日：2003-11-13
申请号：PCT/US2003/013285
申请日：2003-04-30
申请人： MICROLIN, L.C. , DURECT CORPORATION
发明人： JOSHI, Ashok, V. , ZECEVIC, Strahinja , BHAVARAJU, Sai , THEEUWES, Felix , WRIGHT, Jeremy, Corwin
IPC分类号： A61K9/22
CPC分类号： A61M5/1452 , A61K9/0004 , A61K9/0024 , A61M5/14276 , A61M5/14526 , A61M2005/14513
摘要： A fluid delivery device (10), comprising an electrochemical pump (18), wherein the pump is capable of transporting water (26), a pump product chamber (16), wherein the pump product chamber is capable of retaining water generated from the pump, a displaceable member (14) positioned between the pump product chamber and a reservoir (12), wherein the displaceable member is controllably displaced upon generation of water from the electrochemical pump; a reservoir (12), wherein the reservoir is capable of containing a fluid (22) which is delivered upon displacement of the displaceable member, and the reservoir.
摘要翻译：一种流体输送装置（10），包括电化学泵（18），其中泵能够输送水（26），泵产品室（16），其中泵产品室能够保留从泵产生的水，位于所述泵产品室和储存器（12）之间的可移位构件（14），其中所述可移位构件在从所述电化学泵产生水时可控地移位; 储存器（12），其中所述储存器能够容纳在所述可移位构件和所述储存器移位时被输送的流体（22）。

8. 发明申请

WO2003043930A3 FOLDABLE, REFILLABLE, SUSTAINED-RELEASE FLUID DELIVERY SYSTEM 审中-公开
公开(公告)号：WO2003043930A3
公开(公告)日：2003-05-30
申请号：PCT/US2002/037374
申请日：2002-11-20
申请人： MICROLIN, L.C.
IPC分类号： A24F25/00
摘要： The invention described herein is a framed fluid delivery device that is made up of a fluid-delivery cartridge (12) for the timed-release delivery of a fluid contained therein, and a frame assembly (38) for retaining the fluid delivery cartridge (12). The frame assembly (38) is made up of a base portion (40) that facilitates the delivery of fluid released from the fluid-delivery cartridge (12), and at least one side panel (48) associated with the base portion (40) that secures the fluid-delivery cartridge (12) within the frame assembly (38) proximate the element (43) that faciliates the delivery of fluid released. Additionally, a fluid delivery device that includes a fluid-delivery cartridge (12) for the timed-release delivery of a fluid contained therein, the fluid-delivery cartridge (12) having a bottom, a top, and sides, and a dispersion pad (100) positioned proximate the bottom of the fluid-delivery cartridge (12), wherein the dispersion pad (100) at least partially surrounds the sides of the fluid-delivery cartridge (12).

9. 发明申请

WO2002069935A1 FLUID DELIVERY DEVICE AND ASSOCIATED METHOD 审中-公开
标题翻译：流体输送装置及相关方法
公开(公告)号：WO2002069935A1
公开(公告)日：2002-09-12
申请号：PCT/US2002/004899
申请日：2002-02-20
申请人： MICROLIN, L.C.
发明人： JOSHI, Ashok, V.
IPC分类号： A61K9/22
CPC分类号： A61M5/14244 , A61M2005/14204 , A61M2005/14513
摘要： A fluid delivery device (10) comprising a chamber (12) or electrode (30, 32), wherein the chamber (12) or electrode (30) is capable of containing a chemical (20) and/or electrochemical reagent which expands upon a chemical reaction of the same. The expansion, in turn, displaces a displaceable member (16) which facilitates delivery of fluid (22) from an associated reservoir (14).
摘要翻译：一种包括腔室（12）或电极（30,32）的流体输送装置（10），其中腔室（12）或电极（30）能够容纳化学物质（20）和/或电化学试剂化学反应相同。该膨胀又移动了可移动构件（16），其易于从相关联的贮存器（14）输送流体（22）。

10. 发明申请

WO2006007559A3 DEVICE EMPLOYING GAS GENERATING CELL FOR FACILITATING CONTROLLED RELEASE OF FLUID INTO AMBIENT ENVIRONMENT 审中-公开
公开(公告)号：WO2006007559A3
公开(公告)日：2006-01-19
申请号：PCT/US2005/023523
申请日：2005-07-01
申请人： MICROLIN, L.C.
发明人： WOLD, Truman , MCEVOY, John, J. , MUDERLAK, Kenneth, J. , MUDERLAK, Todd, J. , CHUAH, David , BELLINGER, Sean
IPC分类号： A61L9/015 , A61L9/04 , A24F25/00
摘要： A device for controllably releasing a fluid into an ambient environment. According to a particular embodiment of the present invention, the device comprises a housing having a fluid compartment and an orifice compartment disposed adjacent thereto and in fluid communication therewith via an orifice. The fluid compartment contains the fluid for release to the ambient environment. The orifice compartment includes a fluid exit opening covered by a removable sealing element and contains an initial quantity of fluid when the device is in an inactivated state. A fluid restrictor is disposed adjacent the orifice to restrict fluid flow from the fluid compartment into the orifice compartment in the inactivated state. A gas-generating cell is in selective communication with the fluid compartment such that gas generated by the cell is directed into the fluid compartment when the device is in an activated state. A fluid membrane is disposed between the gas-generating cell and the fluid compartment that allows the gas generated by the cell to pass therethrough to the fluid compartment in the activated state while preventing fluid within the fluid container from passing therethrough to the cell in the inactivated state. The device is activated by removing the sealing element to allow the initial quantity of fluid to exit out of the orifice compartment via the fluid exit opening and activating the cell to generate gas and force fluid from the fluid compartment to the orifice compartment and out the fluid exit opening in a controlled manner.

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