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1. 发明申请

WO2005123153A2 DEVICE EMPLOYING GAS GENERATING CELL FOR FACILITATING CONTROLLED RELEASE OF FLUID INTO AMBIENT ENVIRONMENT 审中-公开
标题翻译：使用气体生成装置的装置，以便将流体控制释放到环境环境中
公开(公告)号：WO2005123153A2
公开(公告)日：2005-12-29
申请号：PCT/US2005/021022
申请日：2005-06-14
申请人： MICROLIN, L.C.
发明人： JOSHI, Ashok, V. , WOLD, Truman , McEVOY, John, J.
IPC分类号： A61L9/04
CPC分类号： A61L9/037 , A61L9/122 , A61L9/127
摘要： A device for controllably releasing a fluid into an ambient environment. According to a particular embodiment of the present invention, the device comprises a housing having a fluid compartment and an orifice compartment disposed adjacent thereto and in fluid communication therewith via an orifice. The fluid compartment contains the fluid for release to the ambient environment. The orifice compartment includes a fluid exit opening covered by a removable sealing element and contains an initial quantity of fluid when the device is in an inactivated state. A fluid restrictor is disposed adjacent the orifice to restrict fluid flow from the fluid compartment into the orifice compartment in the inactivated state. A gas-generating cell is in selective communication with the fluid compartment such that gas generated by the cell is directed into the fluid compartment when the device is in an activated state. A fluid membrane is disposed between the gas-generating cell and the fluid compartment that allows the gas generated by the cell to pass therethrough to the fluid compartment in the activated state while preventing fluid within the fluid container from passing therethrough to the cell in the inactivated state. The device is activated by removing the sealing element to allow the initial quantity of fluid to exit out of the orifice compartment via the fluid exit opening and activating the cell to generate gas and force fluid from the fluid compartment to the orifice compartment and out the fluid exit opening in a controlled manner.
摘要翻译：用于将流体可控地释放到周围环境中的装置。根据本发明的特定实施例，该装置包括具有流体隔室和邻近其设置并通过孔流体连通的孔室的壳体。流体室包含用于释放到周围环境的流体。孔室包括由可移除的密封元件覆盖的流体出口，并且当装置处于非活动状态时包含初始量的流体。流体限制器设置在孔口附近以限制处于非活动状态的流体从流体隔室流入孔室。气体发生电池与流体室选择性地连通，使得当该装置处于激活状态时，电池产生的气体被引导到流体室中。流体膜设置在气体发生池和流体隔室之间，其允许由活化的细胞产生的气体通过其流动到活化状态的流体隔室，同时防止流体容器内的流体通过其进入灭活的细胞州。该装置通过移除密封元件而被激活，以允许初始量的流体经由流体出口开口离开孔室，并激活电池以产生气体并迫使流体从流体隔室流到孔室并流出流体以受控的方式出口。

2. 发明申请

WO2005025447A2 DEVICE ΑΝD METHOD FOR WOUND THERAPY 审中-公开
标题翻译：装置治疗方法AlphaNuD
公开(公告)号：WO2005025447A2
公开(公告)日：2005-03-24
申请号：PCT/US2004/029184
申请日：2004-09-08
申请人： MICROLIN, L.C.
发明人： JOSHI, Ashok, V.
IPC分类号： A61F
CPC分类号： A61M1/0066 , A61M1/009 , A61M2202/0208
摘要： A disposable wound-healing device is disclosed that incorporates a housing having a fluid-impermeable material having a cavity and a perimeter that can be sealed in an air-tight manner over a wound region of a patient. The device is capable of producing a negative pressure over the wound region by either removing oxygen from within the cavity, or absorbing fluid into the cavity and then removing the fluid from the cavity. The oxygen may be removed via chemical absorption, by an electrochemical cell or by a chemical reaction that cannibalizes oxygen from the cavity. The fluid may be removed through the use of osmotic or electro osmotic cells, or through a one-way valve. The negative partial pressure over the wound region promotes healing.
摘要翻译：公开了一种一次性伤口愈合装置，其包括具有流体不可渗透材料的壳体，该壳体具有空腔和可以以气密方式密封在患者的伤口区域上的周边。该装置能够通过从空腔内去除氧气或将流体吸入空腔中并且然后从腔体去除流体而在伤口区域上产生负压。氧气可以通过化学吸收，电化学电池或通过使空气中的氧气分解的化学反应来除去。流体可以通过使用渗透或电渗透细胞或通过单向阀去除。伤口区域的负分压促进愈合。

3. 发明申请

WO2005005304A2 MOVING EMANATORS 审中-公开
标题翻译：移动电动机
公开(公告)号：WO2005005304A2
公开(公告)日：2005-01-20
申请号：PCT/US2004/020949
申请日：2004-06-30
申请人： MICROLIN, L.C.
发明人： JOSHI, Ashok, V. , DOMENICK, Lawrence
IPC分类号： B67D
CPC分类号： A61L9/145 , A01M1/2033 , A01M1/205 , A45D34/02 , A61L9/042 , A61L9/127
摘要： A controlled sustained release fluid delivery device is disclosed which has enhanced fluid delivery. The device generally includes a housing having a fluid reservoir therein for holding a fluid, at least one opening in the housing for enabling fluid delivery out of the fluid reservoir and the housing, and structures for delivering the fluid, and retaining the fluid proximate an ambient environment. Once held there, the structure holding the fluid is vibrated so as to enhance the delivery of the fluid to the ambient environment. Other aspects are also disclosed.
摘要翻译：公开了一种受控的持续释放流体输送装置，其具有增强的流体输送。该装置通常包括壳体，其中具有用于保持流体的流体储存器，壳体中的至少一个开口，用于使流体从流体储存器和壳体输出，以及用于输送流体的结构，以及将流体保持在邻近环境环境。一旦保持在那里，保持流体的结构被振动，以便增强流体到周围环境的输送。还公开了其他方面。

4. 发明申请

WO2002069935A1 FLUID DELIVERY DEVICE AND ASSOCIATED METHOD 审中-公开
标题翻译：流体输送装置及相关方法
公开(公告)号：WO2002069935A1
公开(公告)日：2002-09-12
申请号：PCT/US2002/004899
申请日：2002-02-20
申请人： MICROLIN, L.C.
发明人： JOSHI, Ashok, V.
IPC分类号： A61K9/22
CPC分类号： A61M5/14244 , A61M2005/14204 , A61M2005/14513
摘要： A fluid delivery device (10) comprising a chamber (12) or electrode (30, 32), wherein the chamber (12) or electrode (30) is capable of containing a chemical (20) and/or electrochemical reagent which expands upon a chemical reaction of the same. The expansion, in turn, displaces a displaceable member (16) which facilitates delivery of fluid (22) from an associated reservoir (14).
摘要翻译：一种包括腔室（12）或电极（30,32）的流体输送装置（10），其中腔室（12）或电极（30）能够容纳化学物质（20）和/或电化学试剂化学反应相同。该膨胀又移动了可移动构件（16），其易于从相关联的贮存器（14）输送流体（22）。

5. 发明申请

WO2005115356A2 ANTI-MICROBIAL HANDLE SYSTEM 审中-公开
标题翻译：抗微生物手柄系统
公开(公告)号：WO2005115356A2
公开(公告)日：2005-12-08
申请号：PCT/US2005/018500
申请日：2005-05-25
申请人： MICROLIN, L.C.
发明人： JOSHI, Ashok, V.
IPC分类号： A61K9/70
CPC分类号： A61L2/18 , A01N25/34 , A61L2/20 , A61L2/238 , E05B1/0069 , A01N59/00 , A01N59/16 , A01N59/20
摘要： An antimicrobial handle system comprising a handle and an antimicrobial component in communication with the handle to impart antimicrobial properties thereto. According to particular aspects of the invention, the antimicrobial component may be in the form of an antimicrobial material integrally formed with the handle; a handle portion made from an antimicrobial material and removably connected to the handle; an antimicrobial coating disposed on the handle; a film disposed on the handle; an ion generator arrangement in communication with the handle; a sterilizing gas generator in communication with the handle; a sterilizing corona generator in communication with the handle; an antimicrobial lightsource in communication with the handle; a fluid dispenser to dispense an antimicrobial fluid onto the handle; or a combination thereof. The antimicrobial component may include an active oxygen releasing material; an active ozone, UV light, Halide gas, silver ion, or Halide ion releasing material; an antimicrobial fluid; or a photoactive material that exhibits antimicrobial properties when exposed to a light source. Other antimicrobial components are also contemplated in accordance with the principles of the present invention.
摘要翻译：一种抗微生物手柄系统，包括手柄和与手柄连通的抗微生物组件以赋予其抗微生物性质。根据本发明的特定方面，抗微生物组分可以是与手柄一体形成的抗微生物材料的形式; 由抗微生物材料制成并可移除地连接到手柄的手柄部分; 设置在手柄上的抗菌涂层; 设在手柄上的胶片; 与手柄连通的离子发生器装置; 与手柄连通的消毒气体发生器; 与把手连通的消毒电晕发生器; 与手柄通信的抗菌光源; 流体分配器，用于将抗微生物流体分配到手柄上; 或其组合。抗微生物组分可以包括释放活性氧的物质; 活性臭氧，紫外光，卤化物气体，银离子或卤化物离子释放材料; 抗菌液体; 或当暴露于光源时具有抗微生物性质的光敏材料。根据本发明的原理，也考虑了其它抗微生物组分。

6. 发明申请

WO2005005051A2 MOVING EMANATORS 审中-公开
标题翻译：移动EMANATORS
公开(公告)号：WO2005005051A2
公开(公告)日：2005-01-20
申请号：PCT/US2004/021221
申请日：2004-06-30
申请人： MICROLIN, L.C.
发明人： JOSHI, Ashok, V. , DOMENICK, Lawrence
IPC分类号： B05B
CPC分类号： A61L9/145 , A01M1/2033 , A01M1/205 , A45D34/02 , A61L9/042 , A61L9/127
摘要： A controlled sustained release fluid delivery device is disclosed which has enhanced fluid delivery. The device generally includes a housing having a fluid reservoir therein for holding a fluid, at least one opening in the housing for enabling fluid delivery out of the fluid reservoir and the housing, and structures for delivering the fluid, and retaining the fluid proximate an ambient environment. Once held there, the structure holding the fluid is vibrated so as to enhance the delivery of the fluid to the ambient environment. Other aspects are also disclosed.
摘要翻译：公开了一种控制持续释放液输送装置，其具有增强的液体输送。该装置通常包括壳体，壳体中具有用于容纳流体的流体容器，用于使流体能够从流体容器和壳体输出的壳体中的至少一个开口，以及用于输送流体并且将流体保持在环境附近环境。一旦保持在那里，保持流体的结构就会振动，从而增强流体向周围环境的输送。其他方面也被公开。

7. 发明申请

WO2003092662A1 FLUID DELIVERY DEVICE HAVING AN ELECTROCHEMICAL PUMP WITH AN ANIONIC EXCHANGE MEMBRANE AND ASSOCIATED METHOD 审中-公开
标题翻译：具有阴离子交换膜的电化学泵和相关方法的流体输送装置
公开(公告)号：WO2003092662A1
公开(公告)日：2003-11-13
申请号：PCT/US2003/013285
申请日：2003-04-30
申请人： MICROLIN, L.C. , DURECT CORPORATION
发明人： JOSHI, Ashok, V. , ZECEVIC, Strahinja , BHAVARAJU, Sai , THEEUWES, Felix , WRIGHT, Jeremy, Corwin
IPC分类号： A61K9/22
CPC分类号： A61M5/1452 , A61K9/0004 , A61K9/0024 , A61M5/14276 , A61M5/14526 , A61M2005/14513
摘要： A fluid delivery device (10), comprising an electrochemical pump (18), wherein the pump is capable of transporting water (26), a pump product chamber (16), wherein the pump product chamber is capable of retaining water generated from the pump, a displaceable member (14) positioned between the pump product chamber and a reservoir (12), wherein the displaceable member is controllably displaced upon generation of water from the electrochemical pump; a reservoir (12), wherein the reservoir is capable of containing a fluid (22) which is delivered upon displacement of the displaceable member, and the reservoir.
摘要翻译：一种流体输送装置（10），包括电化学泵（18），其中泵能够输送水（26），泵产品室（16），其中泵产品室能够保留从泵产生的水，位于所述泵产品室和储存器（12）之间的可移位构件（14），其中所述可移位构件在从所述电化学泵产生水时可控地移位; 储存器（12），其中所述储存器能够容纳在所述可移位构件和所述储存器移位时被输送的流体（22）。

8. 发明授权

EP1773412B1 DEVICE EMPLOYING GAS GENERATING CELL FOR FACILITATING CONTROLLED RELEASE OF FLUID INTO AMBIENT ENVIRONMENT 有权
标题翻译：与天然气生产电池装置用于液体环境中的控释
公开(公告)号：EP1773412B1
公开(公告)日：2009-09-23
申请号：EP05790118.3
申请日：2005-06-14
申请人： Microlin, L.C.
发明人： JOSHI, Ashok, V. , WOLD, Truman , McEVOY, John, J.
IPC分类号： A62C13/62
CPC分类号： A61L9/037 , A61L9/122 , A61L9/127

9. 发明授权

EP0859875B1 STORAGE-STABLE, FLUID DISPENSING DEVICE USING A HYDROGEN GAS GENERATOR 失效
标题翻译：储存稳定的，LIQUID发光装置使用氢气发生器
公开(公告)号：EP0859875B1
公开(公告)日：2005-12-28
申请号：EP96935953.8
申请日：1996-09-25
申请人： Microlin, L.C.
发明人： JOSHI, Ashok, V. , GORDON, John, H. , McEVOY, John, J.
IPC分类号： C25B9/00 , C25B13/00 , C25B15/08 , A61M5/145
CPC分类号： H01M4/628 , A61M5/145 , A61M2005/14204 , H01M2/0222 , H01M2/027 , H01M2/0275 , H01M2/1044 , H01M2/34 , H01M4/42 , H01M4/50 , H01M4/86 , H01M4/9016 , H01M6/12 , H01M6/26 , H01M6/38 , H01M12/06 , H01M16/00 , H01M2300/0014 , H01M2300/0085 , Y02E60/366

10. 发明申请

WO2002095341A1 FLUID DELIVERY DEVICE HAVING A WATER GENERATING ELECTROCHEMICAL/CHEMICAL PUMP AND ASSOCIATED METHOD 审中-公开
标题翻译：具有水生产电化学/化学泵的流体输送装置及相关方法
公开(公告)号：WO2002095341A1
公开(公告)日：2002-11-28
申请号：PCT/US2002/015629
申请日：2002-05-17
申请人： MICROLIN, L.C. , DURECT CORPORATION
发明人： JOSHI, Ashok, V. , ZECEVIC, Strahinja, K.
IPC分类号： G01F11/00
CPC分类号： A61M5/14526 , A61M2005/14204 , A61M2005/14513 , B67D7/0227
摘要： A fluid delivery device (10) generally including: an electrochemical pump (18), wherein the electrochemical pump (18) is capable of generating water; an electrochemical pump product chamber (16), wherein the electrochemical pump product chamber (16) is capable of retaining water generated from the electrochemical pump (18); a displaceable member (14) positioned between the electrochemical pump product chamber (16) and a reservoir (12), wherein the displaceable member (14) is controllably displaced upon generation of water from the electrical pump; wherein the reservoir (12) is capable of containing a fluid (22) which is delivered upon displacement of the displaceable member (14); and a housing (20) for containing the electrochemical pump (18), the electrochemical pump product chamber (16), the displaceable member (14), and the reservoir (12).
摘要翻译：流体输送装置（10）通常包括：电化学泵（18），其中所述电化学泵（18）能够产生水; 电化学泵产品室（16），其中电化学泵产品室（16）能够保留从电化学泵（18）产生的水; 位于电化学泵产品室（16）和储存器（12）之间的位移构件（14），其中可移动构件（14）在从电动泵产生水时被可控地移位; 其中所述储存器（12）能够容纳在所述可移位构件（14）移位时被输送的流体（22）。以及用于容纳电化学泵（18），电化学泵产品室（16），可移动构件（14）和储存器（12）的壳体（20）。

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