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1. 发明专利

JP2013255811A Systems and methods of determining injection protocols for image diagnosis procedure 有权
标题翻译：用于图像诊断程序的确定注射方案的系统和方法
公开(公告)号：JP2013255811A
公开(公告)日：2013-12-26
申请号：JP2013146563
申请日：2013-07-12
申请人： Medrad Inc , メドラッドインコーポレーテッドMedrad,Inc.
发明人： KALAFUT JOHN F , UBER ARTHUR E
IPC分类号： A61B6/03 , A61B5/055 , A61B6/00 , A61B8/00 , A61M5/00
CPC分类号： A61M5/007 , A61B5/0044 , A61B5/02028 , A61B5/0205 , A61B5/026 , A61B5/029 , A61B5/0295 , A61B5/055 , A61B5/7257 , A61B6/032 , A61B6/481 , A61B6/504 , A61B6/507 , A61B6/583 , A61B8/13 , A61B8/481 , A61K49/0002 , G01R33/5601 , G06F19/321 , G06F19/3468 , G16H50/50
摘要： PROBLEM TO BE SOLVED: To provide methods for adjusting injection protocols with respect to each individual patient.SOLUTION: A step is included for specifying a patient transfer function based on data specific to the patient, wherein the patient transfer function predicts enhancement at desired level, which is output from one or more regions of interest in an individual patient, in response to a predetermined input. A step is included in which, when a fluid containing a contrast-enhancing fluid is diffused, by using scanning data obtained by test-scanning the one or more regions of interest, the output of the enhancement level due to the diffusion of the fluid is determined in synchronization at a plurality of points from each of the one or more regions of interest. By using at least several operation data obtained through the test scanning, the patient transfer function is updated, and a predetermined input is determined through a numerical optimization technique. Injection protocols for individual patient is determined when the predetermined input is input in the patient transfer function, thereby generating the enhancement at desired level in the one or more regions of interest. It is preferable that the injection protocols are managed in relation to diagnostic imaging procedure.
摘要翻译：要解决的问题：提供相对于每个单独患者调整注射方案的方法。解决方案：包括用于根据患者特异性的数据指定患者转移功能的步骤，其中患者转移功能预测在所需水平的增强，其响应于预定输入，从单个患者中的一个或多个感兴趣区域输出。包括其中当包含对比度增强液体的流体扩散时，通过使用通过对一个或多个感兴趣区域进行测试扫描获得的扫描数据，由于流体的扩散而导致的增强水平的输出是在来自所述一个或多个感兴趣区域中的每一个的多个点上同步地确定。通过使用通过测试扫描获得的至少几个操作数据，更新患者传递功能，并且通过数字优化技术确定预定输入。在患者转移功能中输入预定输入时确定个体患者的注射方案，从而在一个或多个感兴趣区域中产生所需水平的增强。优选地，针对诊断成像过程管理注射方案。

2. 发明专利

JPS6463887A PERSONAL DOSIMETER HAVING GAS VOLUME SECTION ON INTEGRATED CIRCUIT 失效
公开(公告)号：JPS6463887A
公开(公告)日：1989-03-09
申请号：JP822288
申请日：1988-01-18
申请人： MEDRAD INC
发明人： AASAA II UUBAA ZA SAADO
IPC分类号： H01L31/09 , G01T1/00 , G01T1/185 , G01T1/24 , G01T7/12 , H01J47/02
摘要： PURPOSE: To provide a personal dose meter which is reduced in size and weight and can accurately measure the total dose and dosage rate of the user by providing the collecting electrodes of ion chambers directly one integrated circuits and compensating the leakage currents between the drains of switching transistors and integrated circuit boards. CONSTITUTION: Ion chambers 16 are formed by defining gas volume sections with semispheric tissue equivalent plastic valves and providing the sections on collecting electrodes incorporated in integrated circuits. Signals from the collecting electrodes are sent to amplifiers 20 and further sent to leakage compensating/discharge controllers 22 in an detector control/interface unit 14. In addition, the value detected by means of a dose/dosage rate calculating and control device 30 is stored in a memory 32 and connected to an operator interface 34 and an electronic interface 36. The interface 34 is provided with an alarm circuit 33. The interfaces and circuits are formed as single or a plurality of ICs. Therefore, the size and weight of a personal dose meter can be reduced and the dose meter can accurately measure the dose/dosage rate of the user.

3. 发明专利

JP2013011441A A device and method for determining activity of radiopharmaceutical agent 审中-公开
标题翻译：用于确定放射性核素的活性的装置和方法
公开(公告)号：JP2013011441A
公开(公告)日：2013-01-17
申请号：JP2010277820
申请日：2010-12-14
申请人： Medrad Inc , メドラッドインコーポレーテッドMedrad,Inc.
发明人： CHAD E BOUTON , ARTHUR E UBER III
IPC分类号： G01T1/167 , G01T1/161 , G01T7/00
CPC分类号： G01T7/02 , A61M5/007
摘要： PROBLEM TO BE SOLVED: To measure a radioactive agent using a detector system.SOLUTION: A fluid path receives at least one aliquot of a radiopharmaceutical. The fluid path locates the aliquot within a positioner formed to have a concave configuration. A detector is located at a certain axial distance from the concave surface and determines the level of radioactivity of the aliquot. Alternatively, the fluid path may be free of concave and a variable attenuator may be placed between the fluid path and the detector. The variable attenuator may have a concavity that is based on the concavity of the fluid path so that the detector's ability to read the radioactivity is optimized. A method for forming an aliquot of a radiopharmaceutical in a concave fluid passage includes arranging a detector to a position separated from the concave surface by a certain distance to optimize reading of spectral energy emitted from the aliquot and activity and determine radioactivity regardless of the position of the aliquot in the passage.
摘要翻译：要解决的问题：使用检测器系统测量放射性试剂。解决方案：流体通道接收放射性药物的至少一个等分试样。流体路径将等分试样定位在形成为具有凹形构型的定位器内。检测器位于距离凹面一定轴向距离处，并确定等分试样的放射性水平。或者，流体路径可以没有凹陷，并且可变衰减器可以被放置在流体路径和检测器之间。可变衰减器可以具有基于流体路径的凹部的凹度，使得检测器读取放射性的能力被优化。在凹形流体通道中形成放射性药物的等分试样的方法包括将检测器布置在与凹面相隔一定距离的位置，以优化从等分试样和活性发射的光谱能量的读数，并确定放射性，而不管通道中的等分试样。版权所有（C）2013，JPO＆INPIT

4. 发明专利

JP2001145697A SYRINGE WHICH CAN BE FILLED IN ADVANCE, AND PLUNGER AND INJECTOR TO BE USED WITH IT 失效
公开(公告)号：JP2001145697A
公开(公告)日：2001-05-29
申请号：JP2000317353
申请日：2000-10-18
申请人： MEDRAD INC
发明人： HITCHINS MARK W , RHINEHART EDWARD J , REILLY DAVID M , MCCOPPIN ANTHONY S , DUFALLA THOMAS L , MASARIK ROBERT J
IPC分类号： A61M5/142 , A61M5/145 , A61M5/28
摘要： PROBLEM TO BE SOLVED: To provide an improved syringe for expanding and/or promoting the kind of medical treatment including the injection of a liquid medium and to provide an injector to be used with it. SOLUTION: A plunger system to be used for this injector operation syringe has a dynamic wedge seal for improving seal connection between a flange cover and a syringe barrel and an elastic grasping member extending from the surface of the rear side of a plunger and allowing the connection and disconnection of the plunger from an injector driving means at an optional plunger position in the syringe. In addition, the plunger system has a contrast media saving chip for pushing out an injection liquid from the tip of the syringe.

5. 发明专利

JPH078468A MRI IMAGE FORMING AND SPECTROSCOPIC PROBE 失效
公开(公告)号：JPH078468A
公开(公告)日：1995-01-13
申请号：JP26863092
申请日：1992-10-07
申请人： MEDRAD INC , UNIV PENNSYLVANIA
发明人： EDOWAADO JIEI RAINHAATO , HAABAATO WAI KURESERU , MITSUCHIERU SHIYUNARU , ROBAATO II RENKINSUKII , BAATON MAIRUSUTOON
IPC分类号： A61B5/055 , A61F2/958 , A61M25/095 , G01R33/28 , G01R33/34
摘要： PURPOSE: To provide a probe to be used for getting a magnetic resonance image of an area of a human body where the access is difficult, such as uterine cervix. CONSTITUTION: A probe 10 comprises a balloon assembly 16 having a pick-up coil inside, on one edge of a shaft 14, and a cuff 62 for preventing the movement, on the other edge. The cuff 62 prevents the movement of the probe at the examination. The balloon assembly comprises an external balloon 26 for making the insertion and installation of the coil easy. An expandable balloon 22 for adjusting the shape of the coil to be fitted to an anatomic area of a particular shape, is installed inside the balloon assembly.

6. 发明专利

JP2011224273A Syringe assembly, method for forming syringe assembly, and adapter for forming syringe assembly 有权
标题翻译：注射器组件，形成SYRINGE组件的方法和用于形成SYRINGE组装的适配器
公开(公告)号：JP2011224273A
公开(公告)日：2011-11-10
申请号：JP2010099351
申请日：2010-04-23
申请人： Medrad Inc , メドラッドインコーポレーテッドMedrad,Inc.
发明人： LISCIO EDWARD P , CASTILLO LUIS , MCNEIL MICHAEL , HITCHINS MARK W
IPC分类号： A61M5/142 , A61M5/145
摘要： PROBLEM TO BE SOLVED: To provide a syringe assembly, a syringe interface used having various types of syringe assembly, and an adapter.SOLUTION: The syringe assembly connectable to an injector having a syringe interface and a driving member includes a barrel portion 110a containing a fluid to be pressurized, and a syringe portion 100a having an exit 132a connected to the barrel portion 110a so as to allow a fluid to flow to the barrel portion 110a and flow back therefrom. The syringe assembly is formed separately from the syringe portion 100a. and includes an adapter 200 that has a plurality of portions. The syringe assembly includes an attaching mechanism having only two portions that engage so that the adapter 200 is immovably connected to the syringe portion 100a, the adapter 200 being configured so as to be connectable to the injector syringe interface.
摘要翻译：要解决的问题：提供一种注射器组件，使用具有各种类型的注射器组件的注射器接口和适配器。解决方案：可连接到具有注射器接口和驱动构件的注射器的注射器组件包括容纳待加压流体的筒部110a和具有连接到筒部110a的出口132a的注射器部分100a，以便允许流体流到筒部110a并从其流出。注射器组件与注射器部分100a分开形成。并且包括具有多个部分的适配器200。注射器组件包括仅具有接合的两个部分的连接机构，使得适配器200不可移动地连接到注射器部分100a，适配器200构造成可连接到注射器注射器接口。版权所有（C）2012，JPO＆INPIT

7. 发明专利

JP2011147796A Device, system and method for determining parameters of one or more phases of injection procedure 审中-公开
标题翻译：用于确定一个或多个注射步骤参数的装置，系统和方法
公开(公告)号：JP2011147796A
公开(公告)日：2011-08-04
申请号：JP2011048581
申请日：2011-03-07
申请人： Medrad Inc , メドラッドインコーポレーテッドMedrad,Inc.
发明人： KALAFUT JOHN F , MISHLER DAVID A
IPC分类号： A61M5/00 , A61M5/142
CPC分类号： A61M5/007 , A61B6/507 , A61M5/14546 , A61M5/16854 , A61M2005/14208 , A61M2205/3334 , A61M2205/50 , A61M2230/04 , G16H40/63
摘要： PROBLEM TO BE SOLVED: To provide devices, systems and methods for delivery of a pharmaceutical fluid to a patient, and, especially for delivery of a contrast medium to a patient during a medical injection procedure.
SOLUTION: A fluid injection apparatus includes at least one pressurizing mechanism and at least a first fluid container (for example, syringe or a bulk container) operably associated with the at least one pressurizing mechanism. The first fluid container is adapted to contain a first fluid to be injected. The fluid injection apparatus also includes a controller operably associated with the at least one pressurizing mechanism. The controller includes a programming system to allow programming of an injection protocol including, for example, a plurality of phases. At least one parameter generator determines parameters of at least one of the plurality of phases based at least in part upon the injection procedure.
COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供用于将药物流体递送到患者的装置，系统和方法，特别是在医疗注射程序期间将造影剂输送给患者。解决方案：流体注射装置包括至少一个加压机构和至少一个可操作地与至少一个加压机构相关联的第一流体容器（例如，注射器或散装容器）。第一流体容器适于容纳要注入的第一流体。流体注射装置还包括可操作地与至少一个加压机构相关联的控制器。控制器包括编程系统，以允许对包括例如多个相位的注入协议进行编程。至少一个参数发生器至少部分地基于注射过程来确定多个相中的至少一个的参数。版权所有（C）2011，JPO＆INPIT

8. 发明专利

JP2006141497A Lesion plotting method and lesion plotting system 审中-公开
标题翻译： LESION绘图方法和LESION绘图系统
公开(公告)号：JP2006141497A
公开(公告)日：2006-06-08
申请号：JP2004332756
申请日：2004-11-17
申请人： Medrad Inc , メドラッドインコーポレーテッドMedrad,Inc.
发明人： KAWAMOTO YASUSHI
IPC分类号： A61B6/03
CPC分类号： A61B6/481 , A61M5/007
摘要： PROBLEM TO BE SOLVED: To provide a more appropriate imaging effect by providing an injection condition required for obtaining a desired imaging effect.
SOLUTION: A lesion plotting method includes the steps of: injecting a small amount of a contrast agent from a syringe 8 only for time Tn and measuring a change in the blood concentration of the contrast agent by using an imaging apparatus 2; adding data based on the change in the blood concentration of the contrast agent at the time Tn over the time Tc required for injecting the contrast agent for an amount required for diagnosing and predicting the imaging effect for the injection required time Tc; and displaying the predicted imaging effect and urging to decide whether or not to change the injection condition of the contrast agent.
COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：通过提供获得期望的成像效果所需的注射条件来提供更合适的成像效果。解决方案：病变绘图方法包括以下步骤：仅从时间Tn从注射器8注入少量的造影剂，并通过使用成像装置2测量造影剂的血液浓度的变化; 基于在注射造影剂所需的时间Tc以上的时间Tn处的造影剂的血液浓度的变化的数据，用于诊断和预测注射所需时间Tc的成像效果所需的量; 并显示预测的成像效果并促使判定是否改变造影剂的注射状态。版权所有（C）2006，JPO＆NCIPI

9. 发明专利

JP2002017852A SYRINGE 失效
公开(公告)号：JP2002017852A
公开(公告)日：2002-01-22
申请号：JP2000318814
申请日：2000-10-19
申请人： MEDRAD INC , SCHERING AG
发明人： KAKIMI MITSURU , HITCHINS MARK W
IPC分类号： A61M5/315 , A61M5/00 , A61M5/142 , A61M5/145
摘要： PROBLEM TO BE SOLVED: To provide a syringe without causing any separated settlings of the elastic cover of a plunger in spite of high-pressure injection when the plunger advances into the syringe. SOLUTION: In the medical syringe 2 for fitting the plunger 4 into a syringe body 3 and advancing the plunger 4 with respect to the body 3 relatively to infuse an infusion agent filling a plunger body 5 into the circulatory system of a human body, the plunger 4 consists of the body 5 and the elastic cover 9 covering the body from its front side, the body 5 is provided with a back plate 62 at its rear end, an annular groove 68 opening forward is formed at the outer peripheral part of the front surface of the plate 62 to allow a part extended to the rear of the cover 9 when the plunger 4 advances to enter the groove 68 to escape.

10. 发明专利

JPS5689239A RECORDING APPARATUS FOR USE WITH IMPLANTING TYPE AUTOMATIC CELL REMOVING DEVICE 失效
公开(公告)号：JPS5689239A
公开(公告)日：1981-07-20
申请号：JP13224480
申请日：1980-09-22
申请人： MEDRAD INC , UNIV JOHNS HOPKINS
发明人： ROBAATO ERENTATSUCHI FUITSUSHI
IPC分类号： A61B5/0402 , A61B5/0432 , A61B5/0436 , A61N1/37 , A61N1/372 , A61N1/39
摘要： The invention relates to a system and apparatus, particularly adapted for use with an automatic implantable defibrillator, for monitoring electrocardiagram (ECG) data signals to provide a continuously updated recording of the ECG data. The proposed recorder responds to the operating condition of the automatic implanted defibrillator device and places into storage, for subsequent readout by the patient's doctor, ECG data both immediately preceding the onset of a ventricular fibrillation episode and also during the subsequent defibrillation activity, when one or more high energy electrical impulses are applied to the patient's heart. Selected other data regarding operation of the implanted defibrillator and pertinent to the doctor's evaluation of the patient's condition as well as the efficacy of the defibrillator unit, are also recorded by the proposed apparatus for subsequent readout. In addition, the proposed recording apparatus operates to automatically alert the patient that ventricular fibrillation has been detected and that defibrillation is to be attempted, so that appropriate precautions may be taken. Moreover, following defibrillation, the patient is alerted in a distinctive manner that defibrillation has occurred and that a physician should be contacted, as soon as possible.

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