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    • 4. 发明授权
    • Manufacture of amides
    • 制造酰胺
    • US07816106B2
    • 2010-10-19
    • US10580446
    • 2004-11-22
    • Yvonne ArmitageJatinder Singh Kullar
    • Yvonne ArmitageJatinder Singh Kullar
    • C12P13/02C12P1/04C12N1/04C12N1/20C12N1/00
    • C12P13/02Y10S435/822
    • A method of producing an amide from the corresponding nitrile comprising the following steps, i) providing a microorganism capable of producing a nitrile hydratase biocatalyst, ii) culturing the microorganism in a growth medium, iii) storing the microorganism, iv) contacting the nitrile by the microorganism in an aqueous medium and thereby converting the nitrile to the amide, wherein the microorganism is stored as none actively growing free cells in a storage medium that comprises water. The stored microorganism may be as whole microbial cells, this may be in the form of a cell paste recovered from a fermentation medium; an aqueous suspension of the microbial cells, prepared using a suitable suspending medium such as water, physiological saline solution, or a suitable buffer solution, such as phosphate or comprises the fermentation broth that contains components of the fermentation culture medium and products of microbial culture. The microorganism exhibits no significant loss of activity, for example if stored even for at least 2 days, especially 3 to 28 days.
    • 一种从相应的腈生产酰胺的方法,包括以下步骤:i)提供能够产生腈水合酶生物催化剂的微生物,ii)在生长培养基中培养微生物,iii)储存微生物,iv)使腈接触 微生物在水性介质中,从而将腈转化为酰胺,其中微生物作为无活性生长的游离细胞储存在包含水的储存培养基中。 储存的微生物可以是整个微生物细胞,其可以是从发酵培养基中回收的细胞糊的形式; 使用合适的悬浮介质如水,生理盐水或适当的缓冲溶液(例如磷酸盐)制备的微生物细胞的水性悬浮液,或包含含有发酵培养基的组分和微生物培养产物的发酵液。 微生物显示出不显着的活性损失,例如如果储存至少2天,特别是3至28天。
    • 6. 发明授权
    • Dewatering process
    • 脱水工艺
    • US07749392B2
    • 2010-07-06
    • US10591777
    • 2005-02-28
    • Tony WhittakerPeter NormanDarryl Smith
    • Tony WhittakerPeter NormanDarryl Smith
    • C02F11/14
    • C02F1/56C02F1/52C02F9/00C02F11/14C02F2209/09C02F2301/08
    • A process of dewatering an aqueous suspension employing a flocculating system comprising treating the suspension with a flocculating amount of a first flocculant and a dewatering amount of a second flocculant, and subjecting the suspension to mechanical dewatering to form a cake, wherein the first flocculant brings about flocculation and assists thickening of the suspension and the second flocculant further dewaters the suspension, characterized in that the second flocculant is a water-soluble or water swellable polymer that is mixed into the suspension in the form of aqueous composition comprising dissolved or hydrated polymer having a Brookfield viscosity of above 30,000 cps (measured at 20° C.).
    • 一种使用絮凝体系脱水水性悬浮液的方法,包括用絮凝量的第一絮凝剂和脱水量的第二絮凝剂处理悬浮液,并对悬浮液进行机械脱水以形成滤饼,其中第一絮凝剂带来 絮凝和辅助悬浮液的增稠,第二絮凝剂进一步使悬浮液脱水,其特征在于第二絮凝剂是水溶性或水可溶胀的聚合物,其以水性组合物的形式混合到悬浮液中,所述水性组合物包含溶解或水合的聚合物, 布鲁克菲尔德粘度高于30,000cps(在20℃下测量)。
    • 8. 发明授权
    • Colourants encapsulated in polymer matrix
    • 封装在聚合物基质中的着色剂
    • US07648715B2
    • 2010-01-19
    • US10475480
    • 2002-04-19
    • Kishor Kumar MistryKenneth Charles SymesJanine Andrea Preston
    • Kishor Kumar MistryKenneth Charles SymesJanine Andrea Preston
    • A61K9/14
    • C09B67/0097C09B67/0013
    • Polymeric particles comprising a polymeric matrix and colourant distributed throughout the matrix, wherein the polymeric matrix that has been formed from a blend of monomers comprising a first monomer which is an ethylenically unsaturated ionic monomer and a second monomer which is an ethylenically unsaturated hydrophobic monomer which is capable of forming a homopolymer of glass transition temperature in excess of 50° C., and in which the first monomer is a salt of a volatile counterion component, characterized in that the polymeric matrix is impermeable to the colourant The particles obtainable by the process of the invention can be used in a variety of industrial processes, for instance in the manufacture of inks, paper and cosmetics.
    • 包含分散在整个基质中的聚合物基质和着色剂的聚合物颗粒,其中已经由包含作为烯属不饱和离子单体的第一单体和作为烯属不饱和疏水单体的第二单体的单体共混物形成的聚合物基体 能够形成玻璃化转变温度超过50℃的均聚物,其中第一单体是挥发性抗衡离子组分的盐,其特征在于聚合物基质对着色剂是不透过的。可通过以下方法获得的颗粒: 本发明可以用于各种工业过程中,例如在油墨,纸和化妆品的制造中。
    • 9. 发明授权
    • Use of flocculating agents for separating the solid residue in hydrolysed fermentation substrates
    • 使用絮凝剂分离水解发酵底物中的固体残余物
    • US07582444B2
    • 2009-09-01
    • US10523229
    • 2003-07-28
    • Jonathan Hughes
    • Jonathan Hughes
    • C12P1/00C12P13/20
    • C13K1/04Y02E50/16
    • Process for improving the separation efficiency of residual solid matter from the liquid phase of an aqueous acid hydrolysate of a naturally occurring polysaccharide comprising dissolved sugars, and residual acid wherein a flocculating agent(s) is added to the aqueous mixture in an effective amount, and a process of producing fermentation products comprising the steps of, (i) hydrolysing a particulate polysaccharide based plant derived material in an acid medium, and thereby forming an aqueous mixture comprising dissolved sugar and solid matter, (ii) subjecting the aqueous mixture to one or more separation stages in which solid matter are removed from the aqueous phase, (iii) adjusting the pH of the obtained aqueous phase to a pH of at least 4, (iv) fermenting the dissolved sugars of the aqueous phase by a microorganism to produce a fermentation product, (v) isolating the fermentation product, wherein in at least one separation stage in step (ii) a flocculating agent is added to the aqueous mixture in an effective amount.
    • 用于提高含有溶解糖的天然存在的多糖的酸性水解产物的水相中的残留固体物质的分离效率的方法和其中以有效量向所述含水混合物中加入絮凝剂的残余酸,以及 一种生产发酵产物的方法,包括以下步骤:(i)在酸性介质中水解基于多糖的植物衍生物质,从而形成含有溶解的糖和固体物质的水性混合物,(ii)将含水混合物经1或 更多的分离阶段,其中从水相中除去固体物质,(iii)将所得水相的pH调节至至少4的pH,(iv)通过微生物发酵水相的溶解糖以产生 发酵产物,(v)分离发酵产物,其中在步骤(ii)的至少一个分离阶段中,将絮凝剂加入到水溶液 有效的混合物。
    • 10. 发明授权
    • Process for making polymeric particles
    • 制造聚合物颗粒的方法
    • US07271142B2
    • 2007-09-18
    • US10480144
    • 2002-06-14
    • Kishor Kumar MistryBryan David Grey
    • Kishor Kumar MistryBryan David Grey
    • B01J13/08B01J13/22C11D3/37C11D17/08
    • B01J13/08B01J13/22C11D3/3703C11D17/0039
    • A particulate composition comprising particles which consist of a shell wall surrounding a hydrophilic core, wherein the shell wall is formed from a polymeric coacervate and wherein the particles comprise a polymeric amphipathic stabiliser. Also claimed is a process of producing a particulate composition comprising particles which consist of a shell wall surrounding a hydrophilic core, comprising the steps of a) forming an aqueous liquid that contains a wall building material that is capable of forming the shell wall by coacervation, b) dispersing the aqueous liquid into a water immiscible liquid, which comprises a stabilising substance to form a dispersion that comprises aqueous droplets dispersed in a continuous phase of water immiscible liquid, c) subjecting the dispersion to coacervation conditions, such that the wall building material coacervates at the surface of the aqueous doplets, characterised in that the stabilising substance comprises a polymeric amphipathic stabiliser. Preferably the particulate composition obtainable by the process contains an active ingredient and is used in a detergent composition. The active ingredient preferably comprises any of detergency building ingredients, a buffering system and/or a sequesterant and/or detergent builder. Citric acid is a particularly preferred active ingredient.
    • 一种颗粒组合物,其包含由围绕亲水芯的壳壁组成的颗粒,其中所述壳壁由聚合物凝聚层形成,并且其中所述颗粒包含聚合的两亲性稳定剂。 还要求的是制备包含由围绕亲水芯的壳壁组成的颗粒的颗粒组合物的方法,包括以下步骤:a)形成含有能够通过凝聚形成壳壁的壁建筑材料的水性液体, b)将水性液体分散到与水不混溶的液体中,所述液体包含稳定物质以形成分散体,所述分散体包含分散在与水不混溶的液体的连续相中的水滴,c)使所述分散体经受凝聚条件,使得所述壁建筑材料 凝固在水滴性乳头的表面,其特征在于稳定物质包含聚合的两亲性稳定剂。 优选地,通过该方法可获得的颗粒组合物含有活性成分,并用于洗涤剂组合物中。 活性成分优选包含任何去污力建筑成分,缓冲系统和/或螯合剂和/或洗涤剂助洗剂。 柠檬酸是特别优选的活性成分。