专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2007102686A8 PEPTIDES HAVING ACTIVITIES OF INSULIN LIKE GROWTH FACTOR-1 AND THEIR USES 审中-公开
标题翻译：胰岛素样生长因子-1及其用途的活性肽
公开(公告)号：WO2007102686A8
公开(公告)日：2010-03-04
申请号：PCT/KR2007001086
申请日：2007-03-06
申请人： CAREGEN CO LTD , CHUNG YONG JI , KIM YOUNG DEUG , KIM EUN MI
发明人： CHUNG YONG JI , KIM YOUNG DEUG , KIM EUN MI
IPC分类号： C07K14/65
CPC分类号： C07K14/65 , A61K38/00
摘要： The present invention relates to a peptide having the activity of insulin like growth factor-1 (IGF-I) and derived from IGF-I, a composition for improving skin conditions or treating a periodontal disease comprising the peptide. The IGF-I mimicking peptides of this invention have identical functions or actions to natural- occurring IGF-I and much better stability and skin permeation than natural-occurring IGF-I. In these connections, the composition comprising the peptides of this invention can exhibit excellent efficacies on the treatment, prevention and improvement of diseases or conditions demanding IGF-I activities. In addition, the peptides of this invention can be advantageously applied to pharmaceutical compositions, quasi-drugs and cosmetics.
摘要翻译：本发明涉及具有胰岛素样生长因子-1（IGF-I）的活性并且衍生自IGF-I的肽，用于改善皮肤病症或治疗包含该肽的牙周病的组合物。本发明的IGF-I模拟肽对天然存在的IGF-I具有相同的功能或作用，并且比天然存在的IGF-I具有更好的稳定性和皮肤渗透性。在这些连接中，包含本发明的肽的组合物可以在治疗，预防和改善需要IGF-I活性的疾病或病症方面表现出优异的功效。此外，本发明的肽可以有利地应用于药物组合物，准药物和化妆品。

2. 发明申请

WO2010085039A3 NOGGIN-DERIVED PEPTIDE AND USE THEREOF 审中-公开
标题翻译： NOGGIN衍生肽及其用途
公开(公告)号：WO2010085039A3
公开(公告)日：2010-09-16
申请号：PCT/KR2009006930
申请日：2009-11-24
申请人： CAREGEN CO LTD , CHUNG YOUNG JI , KIM YOUNG DEUG , KIM EUN MI , SONG SANG SU , HONG IL , CHO KYOUNG MI , KIM SU MI , HAN SANG MIN
发明人： CHUNG YOUNG JI , KIM YOUNG DEUG , KIM EUN MI , SONG SANG SU , HONG IL , CHO KYOUNG MI , KIM SU MI , HAN SANG MIN
IPC分类号： C07K7/08 , C07K7/06 , C07K14/47
CPC分类号： C07K14/475 , A61K38/00 , C07K5/1019 , C07K2319/00
摘要： The present invention relates to a noggin-derived peptide and to a composition containing same for promoting hair growth, enhancing the condition of the skin, providing an anti-inflammatory function, or preventing or treating bone diseases. The noggin-derived peptide of the present invention performs a function identical or similar to that of natural human noggin, and has a superior stability and skin permeability as compared to the natural human noggin. The composition containing the peptide of the present invention as an active ingredient exhibits remarkably superior effects in treating, preventing, or improving growth factor-related symptoms, e.g. hair loss, skin conditions or stab wounds, and in treating, preventing, or improving symptoms of growth factor over-expression. Therefore, the superior activity and stability of the peptide of the present invention are greatly advantageous for using the peptide of the present invention in medicine, quasi-drugs, and cosmetics.
摘要翻译：本发明涉及一种头蛋白衍生肽及其含有促进毛发生长，增强皮肤状态，提供抗炎功能，或预防或治疗骨病的组合物。本发明的来源于肽的肽具有与天然人头蛋白相同或相似的功能，与天然人头蛋白相比具有优异的稳定性和皮肤透过性。含有本发明的肽作为活性成分的组合物在治疗，预防或改善生长因子相关症状方面表现出显着优异的效果。脱发，皮肤状况或刺伤，以及治疗，预防或改善生长因子过表达的症状。因此，本发明的肽的优异活性和稳定性对于在医药，准药物和化妆品中使用本发明的肽是非常有利的。

3. 发明申请

WO2009125925A3 GROWTH FACTOR-MIMICKING PEPTIDES AND USES THEREOF 审中-公开
标题翻译：生长因子模拟肽及其用途
公开(公告)号：WO2009125925A3
公开(公告)日：2009-12-17
申请号：PCT/KR2009001134
申请日：2009-03-06
申请人： CAREGEN CO LTD , CHUNG YOUNG JI , KIM YOUNG DEUG , KIM EUN MI , CHOI JUN YOUNG
发明人： CHUNG YOUNG JI , KIM YOUNG DEUG , KIM EUN MI , CHOI JUN YOUNG
IPC分类号： C07K14/71
CPC分类号： C07K14/475 , A61K8/64 , A61K38/00 , A61Q7/02 , A61Q19/00 , A61Q19/02 , A61Q19/06 , C07K14/50
摘要： The present invention relates to growth factor-mimicking peptides, and a method and a composition containing the same for improving skin condition or treating a wound. The disclosed growth factor-mimicking peptides have the same functions or activities as a natural human growth factor. Additionally, the peptides ensure excellent stability and skin permeability. Accordingly, the composition containing the peptides exhibits excellent effects on treatment, prevention or improvement of diseases or conditions which are required for activities of the growth factor. Also, the excellent activities and stability of the peptides allow the peptides to be applied to medicines, sanitary aids and cosmetics.
摘要翻译：本发明涉及生长因子模拟肽，以及含有其的用于改善皮肤状况或治疗伤口的方法和组合物。所公开的生长因子模拟肽具有与天然人生长因子相同的功能或活性。此外，这些肽可确保出色的稳定性和皮肤渗透性。因此，含有肽的组合物对于生长因子活性所需的疾病或病症的治疗，预防或改善显示出优异的效果。而且，肽的优异活性和稳定性使肽可以应用于药物，卫生用品和化妆品。

4. 发明申请

WO2007049904A1 PEPTIDES EXHIBITING EFFICACIES OF IMPROVEMENT IN SKIN CONDITIONS OR TREATMENT OF PERIODENTAL DISEASES 审中-公开
标题翻译：皮肤改善皮肤病症或治疗周期性疾病的效果
公开(公告)号：WO2007049904A1
公开(公告)日：2007-05-03
申请号：PCT/KR2006/004350
申请日：2006-10-24
申请人： CAREGEN CO., LTD , CHUNG, Yong ji , KIM, Young deug , KIM, Chung Ryul
发明人： CHUNG, Yong ji , KIM, Young deug , KIM, Chung Ryul
IPC分类号： C07K14/50
CPC分类号： C07K14/503
摘要： The present invention relates to a composition for improving a skin condition or treating a periodontal disease, which comprises as an active ingredient a basic fibroblast growth factor-derived peptide. The peptides of this invention exhibit superior efficacies and much better stability and skin permeation than natural- occurring bFGF. In these connections, the composition comprising the peptides of this invention can exhibit excellent efficacies on improvement in skin conditions and treatment of periodontal diseases. In addition, the peptides of this invention can be advantageously applied to pharmaceutical compositions, cosmetics, toothpaste and compositions for mouth cleaning and caring.
摘要翻译：本发明涉及一种用于改善皮肤状况或治疗牙周病的组合物，其包含作为活性成分的碱性成纤维细胞生长因子衍生肽。与天然存在的bFGF相比，本发明的肽具有优异的功效和更好的稳定性和皮肤渗透性。在这些连接中，包含本发明的肽的组合物可以在改善皮肤状况和治疗牙周病方面表现出优异的效果。此外，本发明的肽可以有利地应用于药物组合物，化妆品，牙膏和用于口腔清洁和护理的组合物。

5. 发明申请

WO2017105161A3 PEPTIDE HAVING SKIN WHITENING ACTIVITY, AND USE THEREOF 审中-公开
标题翻译：具有皮肤美白活性的肽及其用途
公开(公告)号：WO2017105161A3
公开(公告)日：2017-08-10
申请号：PCT/KR2017001315
申请日：2017-02-06
申请人： CAREGEN CO LTD
发明人： CHUNG YONG JI , KIM EUN MI , LEE EUNG-JI , KIM JAN DI
IPC分类号： C07K7/08 , A61K8/64 , A61Q19/02
CPC分类号： A61K8/64 , A61Q19/02 , C07K7/08
摘要： The present invention provides a peptide having skin whitening activity. The present invention exhibits an excellent skin whitening effect by inhibiting melanin generation, inhibiting the activity of tyrosinase, inhibiting the expression of factors related to melanin formation, and inhibiting the movement of melanosomes. The peptide according to the present invention is small in size and thus has outstanding skin permeability. The superior activity and stability of the peptide according to the present invention can be very advantageously applied to cosmetics.
摘要翻译：本发明提供了具有皮肤美白活性的肽。本发明通过抑制黑色素生成，抑制酪氨酸酶的活性，抑制与黑色素形成有关的因子的表达以及抑制黑素体的移动而表现出优异的皮肤增白作用。根据本发明的肽尺寸小并因此具有出色的皮肤渗透性。根据本发明的肽的优越的活性和稳定性可以非常有利地应用于化妆品。

6. 发明申请

WO2008044846A1 PEPTIDES HAVING ACTIVITIES OF EPIDERMAL GROWTH FACTOR AND ITS USES 审中-公开
标题翻译：具有活性生长因子活性及其用途的肽
公开(公告)号：WO2008044846A1
公开(公告)日：2008-04-17
申请号：PCT/KR2007/004895
申请日：2007-10-08
申请人： CAREGEN CO., LTD , CHUNG, Yong-Ji , KIM, Young Deug , KIM, Eun Mi , CHOI, Jun Young , SONG, Sang Su
发明人： CHUNG, Yong-Ji , KIM, Young Deug , KIM, Eun Mi , CHOI, Jun Young , SONG, Sang Su
IPC分类号： C07K14/485 , A61K38/00
CPC分类号： C07K14/485 , A61K8/64 , A61K38/00 , A61Q7/00 , A61Q19/00 , A61Q19/08 , Y02P20/55
摘要： The present invention relates to peptides comprising the amino acid sequence represented by the following formula 1 and having the activities of epidermal growth factor and their uses: Cys-Met-Tyr-Ile-Glu-Linker-Arg-Gly-Asp (1) The EGF-mimicking peptides of the present invention possess identical functions or activities to natural-occurring human EGF and are able to promote the generation of autocrine EGF in cells. In addition the peptides of the present invention are much higher stability and skin penetration potency than natural- occurring EGF. Therefore, the composition containing the peptide exhibits excellent treatment and prevention efficacies on diseases or conditions demanding EGF activities, and can be advantageously applied to pharmaceutical compositions, quasi- drugs and cosmetics.
摘要翻译：本发明涉及包含由下式1表示的氨基酸序列并具有表皮生长因子活性及其用途的肽：Cys-Met-Tyr-Ile-Glu-Linker-Arg-Gly-Asp（1）本发明的EGF模拟肽对天然存在的人类EGF具有相同的功能或活性，并且能促进细胞中自分泌EGF的产生。此外，本发明的肽比天然发生的EGF具有更高的稳定性和皮肤穿透效力。因此，含有肽的组合物对于要求EGF活性的疾病或病症表现出优异的治疗和预防功效，并且可以有利地应用于药物组合物，准药物和化妆品。

7. 发明申请

WO2008130082A1 TGFP-CAP PEPTIDE AND ITS USES 审中-公开
标题翻译： TGFP-CAP肽及其用途
公开(公告)号：WO2008130082A1
公开(公告)日：2008-10-30
申请号：PCT/KR2007/004405
申请日：2007-09-12
申请人： CAREGEN CO., LTD , CHUNG, Yong Ji , KIM, Young Deug , KIM, Eun Mi , CHOI, Jun-Young , KIM, Jin Seuk , SONG, Sang Su , CHO, Kyoung Mi
发明人： CHUNG, Yong Ji , KIM, Young Deug , KIM, Eun Mi , CHOI, Jun-Young , KIM, Jin Seuk , SONG, Sang Su , CHO, Kyoung Mi
IPC分类号： C07K19/00
CPC分类号： C07K14/495 , A61K8/64 , A61K38/00 , A61K38/1841 , A61Q19/02 , C07K7/08
摘要： The present invention relates to a GFP-CAP peptide having an amino acid sequence derived from TGF-β1 (transforming growth factor-β1) and a cell adhesion sequence, wherein the amino acid sequence derived from TGF-β1 consists of the amino acid sequence of SEQ ID NO:1 and the TGFP-CAP peptide is represented by the following formula I: Ile-Trp-Ser-Leu-Asp-Thr-Gln-Tyr-Cell adhesion sequence (I). The TGFP-CAP peptide of the present invention exhibits excellent anti-angiogenic activity. In addition, the TGFP-CAP peptide of the present invention prevents effectively melanin generation in skin to have skin whitening effects. The present peptide shows much higher stability and permeability to skin than natural-occurring TGF-β1. Such plausible activities and safety of the present peptide enable advantageously to application to drugs, quasi-drugs and cosmetics.
摘要翻译：本发明涉及具有衍生自TGF-β1（转化生长因子-β1）的氨基酸序列和细胞粘附序列的GFP-CAP肽，其中衍生自TGF-β1的氨基酸序列由 SEQ ID NO：1，TGFP-CAP肽由下式I表示：Ile-Trp-Ser-Leu-Asp-Thr-Gln-Tyr-细胞粘附序列（I）。本发明的TGFP-CAP肽表现出优异的抗血管生成活性。此外，本发明的TGFP-CAP肽有效地防止皮肤中的黑色素生成，从而具有皮肤美白效果。本发明的肽显示比天然存在的TGF-β1更高的稳定性和对皮肤的渗透性。本发明肽的这种合理的活性和安全性有利地适用于药物，准药物和化妆品。

8. 发明申请

WO2007102686A1 PEPTIDES HAVING ACTIVITIES OF INSULIN LIKE GROWTH FACTOR-1 AND THEIR USES 审中-公开
标题翻译：胰岛素样生长因子-1及其用途的活性肽
公开(公告)号：WO2007102686A1
公开(公告)日：2007-09-13
申请号：PCT/KR2007/001086
申请日：2007-03-06
申请人： CAREGEN CO., LTD , CHUNG, Yong Ji , KIM, Young Deug , KIM, Eun Mi
发明人： CHUNG, Yong Ji , KIM, Young Deug , KIM, Eun Mi
IPC分类号： C07K14/65
CPC分类号： C07K14/65 , A61K38/00
摘要： The present invention relates to a peptide having the activity of insulin like growth factor-1 (IGF-I) and derived from IGF-I, a composition for improving skin conditions or treating a periodontal disease comprising the peptide. The IGF-I mimicking peptides of this invention have identical functions or actions to natural- occurring IGF-I and much better stability and skin permeation than natural-occurring IGF-I. In these connections, the composition comprising the peptides of this invention can exhibit excellent efficacies on the treatment, prevention and improvement of diseases or conditions demanding IGF-I activities. In addition, the peptides of this invention can be advantageously applied to pharmaceutical compositions, quasi-drugs and cosmetics.
摘要翻译：本发明涉及具有胰岛素样生长因子-1（IGF-I）的活性并衍生自IGF-1的肽，用于改善皮肤病症或治疗包含该肽的牙周病的组合物。与天然存在的IGF-I相比，本发明的IGF-I模拟肽与天然存在的IGF-I具有相同的功能或作用，并且具有更好的稳定性和皮肤渗透性。在这些连接中，包含本发明的肽的组合物可以在治疗，预防和改善需要IGF-1活性的疾病或病症方面表现出优异的功效。此外，本发明的肽可以有利地应用于药物组合物，准药物和化妆品。

9. 发明申请

WO2007049905A1 PEPTIDES FOR PROMOTING HAIR GROWTH AND IMPROVING WRINKLE AND COSMETIC COMPOSITIONS COMPRISING THE SAME 审中-公开
标题翻译：用于促进头发生长和改善皱纹的化合物和包含其的化妆品组合物
公开(公告)号：WO2007049905A1
公开(公告)日：2007-05-03
申请号：PCT/KR2006/004352
申请日：2006-10-24
申请人： CAREGEN CO., LTD. , CHUNG, Yong Ji , KIM, Young Deug , KIM, Chung Ryul
发明人： CHUNG, Yong Ji , KIM, Young Deug , KIM, Chung Ryul
IPC分类号： C07K7/06
CPC分类号： C07K14/57581
摘要： The present invention relates to a peptide comprising a specific amino acid sequence possessing human thymosin β-4 (Tβ4) activities and its uses. The peptide of this invention has identical or similar functions or actions to human Tβ4 and its biological activity is almost identical to natural-occurring Tβ4. In addition, the peptide of this invention exhibits much higher stability and skin permeation than natural-occurring Tβ4. In these connections, the composition comprising the peptides of this invention can exhibit excellent efficacies on improvement in thymosin β-4-effective disorders or conditions. In addition, the peptide of this invention can be advantageously applied to drugs, cosmetics, toothpaste and compositions for mouth cleaning and caring, most preferably, cosmetics. Specifically, the peptide of this invention is advantageously applied to cosmetics for promoting hair growth.
摘要翻译：本发明涉及包含具有人胸腺素β-4（Tβ4）活性的特定氨基酸序列的肽及其用途。本发明的肽对人类Tβ4具有相同或相似的功能或作用，其生物活性几乎与天然发生的Tβ4相同。此外，与天然存在的Tβ4相比，本发明的肽具有更高的稳定性和皮肤渗透性。在这些连接中，包含本发明的肽的组合物可以在改善胸腺素β-4有效障碍或病症方面表现出优异的效果。此外，本发明的肽可以有利地应用于药物，化妆品，牙膏和用于口腔清洁和护理的组合物，最优选化妆品。具体地说，本发明的肽有利地用于促进头发生长的化妆品中。

10. 发明公开

KR20100097966A Cytokine-derived peptides and uses thereof 有权
标题翻译：细胞因子衍生肽及其用途
公开(公告)号：KR20100097966A
公开(公告)日：2010-09-06
申请号：KR20090016874
申请日：2009-02-27
申请人： CAREGEN CO LTD
发明人： CHUNG YONG JI , KIM YOUNG DEUG , KIM EUN MI , SONG SANG SU , CHO KYOUNG MI , KIM SU MI , HAN SANG MIN
IPC分类号： C07K7/06 , A61K38/08 , A61P29/00 , C07K14/54
CPC分类号： Y02A50/401
摘要： PURPOSE: An IL-13-derived peptide and a composition containing the same are provided to ensure skin penetration and to prevent or treat Th1-mediated immune diseases. CONSTITUTION: An IL-13-derived peptide has an amino acid sequence of sequence number 1. The peptide has an ability of promoting immunocyte proliferation. The immunocyte is B lymphocyte. A composition for preventing or treating Th1-mediated immune diseases contains the IL-13-derived peptide as an active ingredient. The Th1-mediated immune diseases are inflammatory disorders, autoimmune diseases or transplantation rejection.
摘要翻译：目的：提供IL-13衍生的肽及含有这些肽的组合物以确保皮肤渗透并预防或治疗Th1介导的免疫疾病。构成：IL-13衍生的肽具有序列号1的氨基酸序列。肽具有促进免疫细胞增殖的能力。免疫细胞是B淋巴细胞。用于预防或治疗Th1介导的免疫疾病的组合物含有作为活性成分的IL-13衍生肽。 Th1介导的免疫疾病是炎症性疾病，自身免疫性疾病或移植排斥反应。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式