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1. 发明专利

JPH10508251A 失效
公开(公告)号：JPH10508251A
公开(公告)日：1998-08-18
申请号：JP51052297
申请日：1996-08-22
申请人： AEROGEN INC
发明人： IVRI YEHUDA , WU CHENG H
IPC分类号： A61M11/00 , A61M15/00 , A61M16/00 , B05B1/14 , B05B17/06 , B05C11/105

2. 发明专利

JP2013099544A System and method for clearing aerosol from effective anatomic dead space 审中-公开
标题翻译：用于从有效解剖死亡空间中清除气溶胶的系统和方法
公开(公告)号：JP2013099544A
公开(公告)日：2013-05-23
申请号：JP2012285036
申请日：2012-12-27
申请人： Aerogen Inc , エアロジェン,インコーポレイテッド
发明人： KLIMOWICZ MICHAEL , FINK JAMES B
IPC分类号： A61M11/00 , A61M15/00 , A61M16/00
CPC分类号： A61M15/00 , A61M15/0085 , A61M16/024 , A61M2016/0021 , A61M2016/0024 , A61M2205/52 , A61M2205/6045 , A61M2205/6072
摘要： PROBLEM TO BE SOLVED: To provide a preferable aerosolization device.SOLUTION: The aerosolization device 10 has a housing 26 with a mouthpiece 14, an aerosol generator 16, a flow sensor 32, and a controller 28. The controller 28 is configured to begin an operation of the aerosol generator 16 upon receipt of a signal from the flow sensor 32 indicating that a threshold flow rate is achieved by a user when inhaling a tidal breath through the mouthpiece 14, and to stop the operation after the passage of an operation time which is selected such that continuation of the tidal breath delivers substantially all of the aerosol to the lungs.
摘要翻译：要解决的问题：提供优选的雾化装置。解决方案：雾化装置10具有带嘴件14的壳体26，气溶胶发生器16，流量传感器32和控制器28.控制器28构造成在接收到气雾发生器16时开始气溶胶发生器16的操作来自流量传感器32的信号，指示当通过吸嘴14吸入潮气呼吸时由使用者实现阈值流量，并且在经过选择的操作时间之后停止操作，使得持续的潮气将大部分气溶胶输送到肺部。版权所有（C）2013，JPO＆INPIT

3. 发明专利

JP2004001472A Printing system 审中-公开
公开(公告)号：JP2004001472A
公开(公告)日：2004-01-08
申请号：JP2003105900
申请日：2003-04-09
申请人： Aerogen Inc , エアロジェン,インコーポレイテッド
发明人： IVRI YEHUDA
IPC分类号： B41J2/015 , B41J2/04 , B41J2/045 , B41J2/055 , B41J2/175
CPC分类号： B41J2/04 , A61M2205/3306
摘要： PROBLEM TO BE SOLVED: To provide an ink jetting unit capable of jetting an ink by an ink jet frequency higher than 50,000 Hz.
SOLUTION: A cantilever beam 12 is mounted on a piezoelectric element 18 via a base end for vibrating the base end 14. The beam is formed in a shape such that the inertial moment is reduced toward the free end. The piezoelectric element is driven by an oscillation electric signal of a frequency close to the natural frequency of the beam vibration. According to the beam structure and a predetermined frequency of the vibration, a chip 15 of the beam is oscillated by a frequency higher than the oscillation frequency of the base end. The chip of the beam is provided with a through hole tapered in the cross section such that one of the openings of the through hole communicates with an ink reservoir 17 by fluid connection, and the other end is provided at an optional distance from a recording medium. In the case the amplitude of the chip exceeds a predetermined threshold, a droplet of the ink is accelerated via the through hole so as to be jetted each time the chip of the beam is displaced toward the printing medium.
COPYRIGHT: (C)2004,JPO

4. 发明专利

JP2008289903A Vibratable aperture plate 有权
标题翻译：振动孔板
公开(公告)号：JP2008289903A
公开(公告)日：2008-12-04
申请号：JP2008179570
申请日：2008-07-09
申请人： Aerogen Inc , エアロジェン,インコーポレイテッド
发明人： IVRI YEHUDA , DE YOUNG LINDA R , WU CHENG H , CATER MIRO S , KUMAR VIJAY , FLIERL MARKUS
IPC分类号： A61M11/00 , A61M15/00 , A61M5/30 , A61M16/00 , B05B9/04 , B05B11/00 , B05B12/08 , B05B17/06 , B41J2/025 , C25D1/08
CPC分类号： B05B17/0684 , A61M15/0028 , A61M15/0065 , A61M15/0085 , A61M15/025 , A61M2016/0021 , A61M2016/0039 , A61M2205/0233 , A61M2205/3306 , A61M2205/8206 , B05B11/0048 , B05B11/309 , B05B11/3094 , B05B12/08 , B05B17/0646 , B41J2/025 , C25D1/08
摘要： PROBLEM TO BE SOLVED: To provide a way to store a solid substance and combine the solid substance with a liquid to form solution, and to rapidly transport the solution to an atomization device to allow the solution to be aerolized for administration, once the solution is formed.
SOLUTION: The vibratable aperture plate includes a front surface 50, a rear surface 48, and a plurality of tapered apertures 46 extending from the front surface 50 to the rear surface 48, and wherein the plate body constructed from palladium in a major amount. The solution is aerosolized immediately after reconstruction of the solution so as to slow the rate of degradation of the substance.
COPYRIGHT: (C)2009,JPO&INPIT
摘要翻译：要解决的问题：提供一种存储固体物质并将固体物质与液体结合以形成溶液的方法，并将溶液快速输送到雾化装置，以使溶液气化以进行给药，一次形成溶液。解决方案：可振动孔板包括前表面50，后表面48和从前表面50延伸到后表面48的多个锥形孔46，并且其中由主体由钯构成的板体量。重建溶液后立即将溶液雾化，以减缓物质的降解速率。版权所有（C）2009，JPO＆INPIT

5. 发明专利

JP2002154203A METHOD OF PRINTING 审中-公开
公开(公告)号：JP2002154203A
公开(公告)日：2002-05-28
申请号：JP2001298282
申请日：2001-09-27
申请人： AEROGEN INC
发明人： IVRI YEHUDA
IPC分类号： B41J2/015 , B41J2/04 , B41J2/045 , B41J2/055 , B41J2/175
摘要： PROBLEM TO BE SOLVED: To provide an ink jet ejection device capable of ejecting ink by an ink jet frequency greater than 50,000 Hz. SOLUTION: A cantilevered beam 12 is mounted at its base 14 to a piezoelectric element 18 which oscillates the base 14. The beam is shaped so that it s moment of inertia is gradually reduced toward its fee end. The piezoelectric element is activated by an oscillating electrical signal of which the frequency is equal to or close to a natural frequency of oscillation of the beam. A tip 15 of the beam oscillates in a frequency higher than the oscillation frequency of the base by virtue of the structure of the beam and a predetermined frequency of the oscillation. The tip of the beam is provided with an aperture which is tapered in its cross-section. One opening of the aperture is in fluid communication with an ink reservoir 17 and the other opening is positioned at an appropriate distance from a recording medium. When the amplitude of the tip is above a predetermined threshold, a drop of ink is accelerated through the aperture and is ejected upon each excursion of the tip of the beam toward a printing medium.

6. 发明专利

JP2010279733A System and method for clearing aerosol from effective anatomic dead space 审中-公开
标题翻译：用于从有效解剖死亡空间中清除气溶胶的系统和方法
公开(公告)号：JP2010279733A
公开(公告)日：2010-12-16
申请号：JP2010182645
申请日：2010-08-17
申请人： Aerogen Inc , エアロジェン,インコーポレイテッド
发明人： KLIMOWICZ MICHAEL , FINK JAMES B
IPC分类号： A61M15/00 , A61M16/00
CPC分类号： A61M15/00 , A61M15/0085 , A61M16/024 , A61M2016/0021 , A61M2016/0024 , A61M2205/52 , A61M2205/6045 , A61M2205/6072
摘要： PROBLEM TO BE SOLVED: To provide a technique to make movement of an aerosol to the lungs easy and a device designed such.
SOLUTION: An aerosolization device 10 has a housing 26 with a mouthpiece 14, an aerosol generator 16, a flow sensor 32, and a controller 28. The controller 28 is configured to begin operation of the aerosol generator 16 upon receipt of a signal from the flow sensor 32 indicating that a threshold flow rate is achieved by a user when inhaling a tidal breath through the mouthpiece 14, and to stop operation after the passage of an operation time which is selected such that continuation of the tidal breath delivers substantially all of the aerosol to the lungs.
COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译：要解决的问题：提供使气溶胶向肺部移动容易的技术和设计的装置。解决方案：雾化装置10具有带嘴件14的壳体26，气溶胶发生器16，流量传感器32和控制器28.控制器28构造成在接收到气雾发生器16时开始操作气溶胶发生器16 来自流量传感器32的信号，指示当通过吸嘴14吸入潮气呼吸时，用户实现阈值流量，并且在通过选择的操作时间之后停止操作，使得持续的潮气呼吸基本上递送所有的气雾剂到肺部。版权所有（C）2011，JPO＆INPIT

7. 发明专利

JP2006150093A Method and system for operating aerosol generator 审中-公开
标题翻译：用于航空发电机操作的方法和系统
公开(公告)号：JP2006150093A
公开(公告)日：2006-06-15
申请号：JP2006006801
申请日：2006-01-13
申请人： Aerogen Inc , エアロジェン,インコーポレイテッド
发明人： SMITH NIALL , POWER JOHN , FINK JAMES B , KLIMOWICZ MICHAEL
IPC分类号： A61K9/12 , A61M15/00 , A61J1/06 , A61K47/04 , A61M16/00 , A61M16/04 , A61M16/06 , A61M16/08 , B05B15/00 , B05B17/06 , B65D1/09
CPC分类号： A61J1/065 , A61J2205/10 , A61J2205/60 , A61M15/00 , A61M15/0028 , A61M15/0031 , A61M15/0033 , A61M15/0085 , A61M16/024 , A61M16/04 , A61M16/06 , A61M16/08 , A61M2016/0021 , A61M2016/0024 , A61M2205/52 , A61M2205/6045 , A61M2205/6054 , A61M2205/6072 , A61M2205/8206 , A61M2205/8262 , A61M2209/082 , B05B17/0646 , B65D1/095 , B65D2203/00
摘要： PROBLEM TO BE SOLVED: To provide an aerosol generator capable of acquiring information on the contents of a nebulizer. SOLUTION: A method of creating an aerosol comprises processes of providing the aerosol generator; coupling the nebulizer to an interface of the aerosol generator; reading an identification marker on the nebulizer; and operating the aerosol generator according to an operation program based on the information read from the identification marker on the nebulizer. The operating process comprises selecting the operation program from a plurality of stored operation programs and informing a user of the type of liquid based on the information read from the identification marker. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译：要解决的问题：提供能够获取关于雾化器的内容的信息的气溶胶发生器。解决方案：产生气溶胶的方法包括提供气溶胶发生器的方法; 将喷雾器耦合到气溶胶发生器的界面; 读取雾化器上的识别标记; 并且根据基于从雾化器上的识别标记读取的信息的操作程序来操作气溶胶发生器。操作过程包括从多个存储的操作程序中选择操作程序，并且基于从识别标记读取的信息向用户通知该类型的液体。版权所有（C）2006，JPO＆NCIPI

8. 发明申请

WO2005009323A3 A NEBULISER FOR THE PRODUCTION OF AEROSOLIZED MEDICATION 审中-公开
标题翻译：用于生产气溶胶药物的基础
公开(公告)号：WO2005009323A3
公开(公告)日：2005-05-06
申请号：PCT/US2004021628
申请日：2004-07-06
申请人： AEROGEN INC , POWER JOHN , MORAN DECLAN , DEVERY DONAL , O'SULLIVAN GAVAN , FINK JAMES , SMITH NIALL
发明人： POWER JOHN , MORAN DECLAN , DEVERY DONAL , O'SULLIVAN GAVAN , FINK JAMES , SMITH NIALL
IPC分类号： A61M15/00 , A01G23/10 , A61M11/00 , A61M11/06 , B05B1/08 , B05B17/04
CPC分类号： A61M15/0085 , A61M2205/8206 , A61M2205/8237 , B05B17/0607
摘要： A nebuliser to deliver a medicament that includes a housing having a reservoir for the medicament, an aerosol generator that can be supplied the medicament from the reservoir, where the generator aerosolizes at least a portion of the medicament into an aerosol, a gas venting inlet to permit a gas to enter the nebuliser and form a mixture with the aerosol, and a passage through which the mixture of the aerosol and the gas is delivered to an outlet port of the nebuliser.
摘要翻译：一种用于递送药物的雾化器，其包括具有用于药物的储存器的壳体，可从储存器供应药物的气溶胶发生器，其中发生器将至少一部分药物雾化成气溶胶，气体通气入口允许气体进入雾化器并与气溶胶形成混合物，以及将气溶胶和气体的混合物输送到雾化器的出口的通道。

9. 发明申请

WO2003057291A1 DEVICES AND METHODS FOR NEBULIZING FLUIDS FOR INHALATION 审中-公开
标题翻译：用于吸入流体的流体的装置和方法
公开(公告)号：WO2003057291A1
公开(公告)日：2003-07-17
申请号：PCT/US2003/000504
申请日：2003-01-07
申请人： AEROGEN, INC.
发明人： PATEL, Rajan , KLIMOWICZ, Michael, A.
IPC分类号： A61M11/00
CPC分类号： A61M15/0085 , A61M11/005 , A61M11/007 , A61M15/0065 , A61M15/0066 , A61M2016/0021 , A61M2016/0024 , A61M2205/50 , A61M2205/583 , A61M2205/584 , A61M2205/8206 , B05B17/0646
摘要： A nebulizer comprising an aerosol generator (100) and a titration mechanism (20) comprising a dosing mechanism (30), a screw assembly (50), a plunger (60) and an actuator (40), wherein the dosing mechanism is rotatably mounted in the nebulizer and the plunger is mounted in the nebulizer to travel along a longitudinal axis (62) substantially perpendicular to the plane of rotation of the dosing mechanism. The actuator is mounted to the nebulizer to travel in the direction (42) of the longitudinal axis. The screw mechanism allows the rotation of the dosing mechanism to fix a variable distance of travel of the plunger based on the selected dose, without moving the plunger longitudinally. This allows the user to verify and if necessary correct the selected dose prior to any drug being released from the vial. Operation of the actuator causes longitudinal movement, through the screw mechanism, to the plunger.
摘要翻译：一种喷雾器，包括气溶胶发生器（100）和包括计量机构（30），螺杆组件（50），柱塞（60）和致动器（40）的滴定机构（20），其中所述计量机构可旋转地安装在雾化器中并且柱塞被安装在喷雾器中以沿着基本上垂直于配料机构的旋转平面的纵向轴线（62）行进。致动器安装到喷雾器以沿纵向轴线的方向（42）行进。螺杆机构允许计量机构的旋转基于所选择的剂量来固定柱塞的可变行程距离，而不纵向移动柱塞。这允许用户在从药瓶释放任何药物之前验证并且必要时校正所选择的剂量。致动器的操作使得纵向运动通过螺杆机构到柱塞。

10. 发明申请

WO0236181A9 PIEZOELECTRIC POLYMER FLOW SENSOR AND METHODS 审中-公开
标题翻译：压电聚合物流量传感器及方法
公开(公告)号：WO0236181A9
公开(公告)日：2002-07-25
申请号：PCT/US0147564
申请日：2001-11-02
申请人： AEROGEN INC
发明人： IVRI YEHUDA , SMITH NIALL , POWER JOHN
IPC分类号： A61M15/00 , A61M16/00 , A61M
CPC分类号： A61M15/0085 , A61M2016/0024
摘要： An aerosolization system comprises a gas flow passage, and an aerosol generator comprising a plate having a plurality of apertures and a vibratable element disposed to vibrate the plate. The aerosol generator is adapted to aerosolize a liquid for delivery into the gas flow passage. A flow sensor is configured to sense a gas flow through the passage, and a controller is employed to actuate the aerosol generator based on the gas flow sensed by the flow sensor.
摘要翻译：雾化系统包括气流通道和气溶胶发生器，其包括具有多个孔的板和设置成使板振动的可振动元件。气溶胶发生器适于使液体雾化以输送到气体流动通道中。流量传感器被配置为感测通过通道的气体流量，并且使用控制器来基于由流量传感器感测的气流来致动气溶胶发生器。

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