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1. 发明授权

US07796725B1 Mechanism for switching sources in x-ray microscope 有权
标题翻译： x射线显微镜切换源的机制
公开(公告)号：US07796725B1
公开(公告)日：2010-09-14
申请号：US12401750
申请日：2009-03-11
申请人： Ziyu Wu , Wenbing Yun , Peiping Zhu , Yuxin Wang , Qingxi Yuan , Andrei Tkachuk , Wanxia Huang , Michael Feser
发明人： Ziyu Wu , Wenbing Yun , Peiping Zhu , Yuxin Wang , Qingxi Yuan , Andrei Tkachuk , Wanxia Huang , Michael Feser
IPC分类号： G21K7/00
CPC分类号： G21K7/00 , H01J2235/00
摘要： An x-ray imaging system uses a synchrotron radiation beam to acquire x-ray images and at least one integrated x-ray source. The system has an imaging system including sample stage controlled by linear translation stages, objective x-ray lens, and x-ray sensitive detector system, placed on a fixed optical table and a mechanical translation stage system to switch x-ray sources when synchrotron radiation beam is not available.
摘要翻译： X射线成像系统使用同步加速器辐射束来获取x射线图像和至少一个集成的x射线源。该系统具有成像系统，包括由线性平移台控制的样本台，物镜X射线透镜和x射线敏感探测器系统，放置在固定的光学平台和机械平移台系统上以在同步加速器辐射时切换x射线源光束不可用。

2. 发明授权

US07813475B1 X-ray microscope with switchable x-ray source 有权
标题翻译：具有可切换x射线源的X射线显微镜
公开(公告)号：US07813475B1
公开(公告)日：2010-10-12
申请号：US12401740
申请日：2009-03-11
申请人： Ziyu Wu , Wenbing Yun , Peiping Zhu , Yuxin Wang , Qingxi Yuan , Andrei Tkachuk , Wanxia Huang , Michael Feser
发明人： Ziyu Wu , Wenbing Yun , Peiping Zhu , Yuxin Wang , Qingxi Yuan , Andrei Tkachuk , Wanxia Huang , Michael Feser
IPC分类号： G01N23/04
CPC分类号： G21K7/00 , H01J2235/00
摘要： An x-ray imaging system uses a synchrotron radiation beam to acquire x-ray images and at least one integrated x-ray source. The system has an imaging system including sample stage controlled by linear translation stages, objective x-ray lens, and x-ray sensitive detector system, placed on a fixed optical table and a mechanical translation stage system to switch x-ray sources when synchrotron radiation beam is not available.
摘要翻译： X射线成像系统使用同步加速器辐射束来获取x射线图像和至少一个集成的x射线源。该系统具有成像系统，包括由线性平移台控制的样本台，物镜X射线透镜和x射线敏感探测器系统，放置在固定的光学平台和机械平移台系统上以在同步加速器辐射时切换x射线源光束不可用。

3. 发明申请

US20120041679A1 LOW DOSE SINGLE STEP GRATING BASED X-RAY PHASE CONTRAST IMAGING 有权
标题翻译：低剂量单步色差X射线相位对比成像
公开(公告)号：US20120041679A1
公开(公告)日：2012-02-16
申请号：US13148198
申请日：2010-02-03
申请人： Marco Stampanoni , Ziyu Wu , Peiping Zhu
发明人： Marco Stampanoni , Ziyu Wu , Peiping Zhu
IPC分类号： G06F19/00
CPC分类号： G01N23/04 , A61B6/00 , A61B6/4291 , A61B6/484
摘要： Phase sensitive X-ray imaging methods provide substantially increased contrast over conventional absorption based imaging, and therefore new and otherwise inaccessible information. The use of gratings as optical elements in hard X-ray phase imaging overcomes some of the problems impairing the wider use of phase contrast in X-ray radiography and tomography. To separate the phase information from other contributions detected with a grating interferometer, a phase-stepping approach has been considered, which implies the acquisition of multiple radiographic projections. Here, an innovative, highly sensitive X-ray tomographic phase contrast imaging approach is presented based on grating interferometry, which extracts the phase contrast signal without the need of phase stepping. Compared to the existing phase step approach, the main advantage of this new method dubbed “reverse projection” is the significantly reduced delivered dose, without degradation of the image quality.
摘要翻译：相对于常规的基于吸收的成像，相敏X射线成像方法提供了显着增加的对比度，因此提供了新的和其他不可接近的信息。在硬X射线相位成像中使用光栅作为光学元件克服了在X射线摄影和断层摄影中损害相对对比度的更广泛使用的一些问题。为了将相位信息与用光栅干涉仪检测到的其他贡献分离，已经考虑了相位步进方法，这意味着获取多个射线照相投影。在这里，基于光栅干涉测量提出了一种创新的，高灵敏度的X射线断层扫描相位成像方法，其提取相位差信号，而不需要相位步进。与现有的相位步法相比，这种被称为“反投影”的新方法的主要优点是显着降低了传送剂量，而不会降低图像质量。

4. 发明授权

US08972191B2 Low dose single step grating based X-ray phase contrast imaging 有权
标题翻译：低剂量单步光栅X射线相位成像
公开(公告)号：US08972191B2
公开(公告)日：2015-03-03
申请号：US13148198
申请日：2010-02-03
申请人： Marco Stampanoni , Ziyu Wu , Peiping Zhu
发明人： Marco Stampanoni , Ziyu Wu , Peiping Zhu
IPC分类号： G01B9/02 , G01N21/31 , G06F3/00 , G06F3/01 , G01N23/04 , A61B6/00
CPC分类号： G01N23/04 , A61B6/00 , A61B6/4291 , A61B6/484
摘要： Phase sensitive X-ray imaging methods provide substantially increased contrast over conventional absorption based imaging, and therefore new and otherwise inaccessible information. The use of gratings as optical elements in hard X-ray phase imaging overcomes some of the problems impairing the wider use of phase contrast in X-ray radiography and tomography. To separate the phase information from other contributions detected with a grating interferometer, a phase-stepping approach has been considered, which implies the acquisition of multiple radiographic projections. Here, an innovative, highly sensitive X-ray tomographic phase contrast imaging approach is presented based on grating interferometry, which extracts the phase contrast signal without the need of phase stepping. Compared to the existing phase step approach, the main advantage of this new method dubbed “reverse projection” is the significantly reduced delivered dose, without degradation of the image quality.
摘要翻译：相对于常规的基于吸收的成像，相敏X射线成像方法提供了显着增加的对比度，因此提供了新的和其他不可接近的信息。在硬X射线相位成像中使用光栅作为光学元件克服了在X射线摄影和断层摄影中损害相对对比度的更广泛使用的一些问题。为了将相位信息与用光栅干涉仪检测到的其他贡献分离，已经考虑了相位步进方法，这意味着获取多个射线照相投影。在这里，基于光栅干涉测量提出了一种创新的，高灵敏度的X射线断层扫描相位成像方法，其提取相位差信号，而不需要相位步进。与现有的相位步法相比，这种被称为“反向投影”的新方法的主要优点是显着降低了递送剂量，而不会降低图像质量。

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