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1. 发明授权

US09007873B2 Clamp type ultrasonic processor and application thereof 有权
标题翻译：夹式超声波处理器及其应用
公开(公告)号：US09007873B2
公开(公告)日：2015-04-14
申请号：US13576398
申请日：2010-11-01
申请人： Zhuosheng Yan , Jinxuan Yan , Zhuoli Yan , Zhizhong Yang , Qiang Ye , Hui Cao , Yanmiao He
发明人： Zhuosheng Yan , Jinxuan Yan , Zhuoli Yan , Zhizhong Yang , Qiang Ye , Hui Cao , Yanmiao He
IPC分类号： H04B1/03 , B22D1/00 , B22D27/20
CPC分类号： B22D1/00 , B22D27/20
摘要： A clamp type ultrasonic processor comprises a transducer assembly and a functional gripper. The transducer assembly comprises a transducer (1) and an amplitude transforming shaft (2) attached thereto. At least one transducer assembly is connected to the functional gripper. The functional gripper comprises an irradiation front line shaft-approximal block (3) and an irradiation front line tube-supporting block (4), and a functional gripper chamber (8) is provided in the functional gripper for accommodating an ultrasonic irradiation receiver. The irradiation front line shaft-approximal block (3) and the irradiation front line tube-supporting block (4) are connected to grip tightly the ultrasonic irradiation receiver to be irradiated. Irradiation front line shaft-approximal block (3) and/or the irradiation front line tube-supporting block (4) are connected to the amplitude transforming shaft (2). An application of the clamp type ultrasonic processor and its application in metal production are also provided.
摘要翻译：夹式超声波处理器包括换能器组件和功能夹持器。换能器组件包括连接到其上的换能器（1）和振幅变换轴（2）。至少一个换能器组件连接到功能夹持器。功能夹持器包括照射前线轴近似块（3）和照射前线管支撑块（4），功能夹持器（8）设置在功能夹持器中，用于容纳超声波照射接收器。照射前线轴近似块（3）和照射前线管支撑块（4）连接以紧紧地夹紧要照射的超声波照射接收器。照射前线轴近似块（3）和/或照射前线管支撑块（4）与振幅变换轴（2）连接。还提供了夹式超声波处理器的应用及其在金属生产中的应用。

2. 发明申请

US20120300590A1 Clamp Type Ultrasonic Processor and Application thereof 有权
标题翻译：夹式超声波处理器及其应用
公开(公告)号：US20120300590A1
公开(公告)日：2012-11-29
申请号：US13576398
申请日：2010-11-01
申请人： Zhuosheng Yan , Jinxuan Yan , Zhuoli Yan , Zhizhong Yang , Qiang Ye , Hui Cao , Yanmiao He
发明人： Zhuosheng Yan , Jinxuan Yan , Zhuoli Yan , Zhizhong Yang , Qiang Ye , Hui Cao , Yanmiao He
IPC分类号： H04B1/03
CPC分类号： B22D1/00 , B22D27/20
摘要： A clamp type ultrasonic processor comprises a transducer assembly and a functional gripper. The transducer assembly comprises a transducer (1) and an amplitude transforming shaft (2) attached thereto. At least one transducer assembly is connected to the functional gripper. The functional gripper comprises an irradiation front line shaft-approximal block (3) and an irradiation front line tube-supporting block (4), and a functional gripper chamber (8) is provided in the functional gripper for accommodating an ultrasonic irradiation receiver. The irradiation front line shaft-approximal block (3) and the irradiation front line tube-supporting block (4) are connected to grip tightly the ultrasonic irradiation receiver to be irradiated. Irradiation front line shaft-approximal block (3) and/or the irradiation front line tube-supporting block (4) are connected to the amplitude transforming shaft (2). An application of the clamp type ultrasonic processor and its application in metal production are also provided.
摘要翻译：夹式超声波处理器包括换能器组件和功能夹持器。换能器组件包括连接到其上的换能器（1）和振幅变换轴（2）。至少一个换能器组件连接到功能夹持器。功能夹持器包括照射前线轴近似块（3）和照射前线管支撑块（4），功能夹持器（8）设置在功能夹持器中，用于容纳超声波照射接收器。照射前线轴近似块（3）和照射前线管支撑块（4）连接以紧紧地夹紧要照射的超声波照射接收器。照射前线轴近似块（3）和/或照射前线管支撑块（4）与振幅变换轴（2）连接。还提供了夹式超声波处理器的应用及其在金属生产中的应用。

3. 发明授权

US09132087B2 Auris formulations for treating otic diseases and conditions 有权
标题翻译：用于治疗耳部疾病和病症的Auris制剂
公开(公告)号：US09132087B2
公开(公告)日：2015-09-15
申请号：US12427663
申请日：2009-04-21
申请人： Jay Lichter , Andrew M. Trammel , Fabrice Piu , Luis A. Dellamary , Qiang Ye , Carl Lebel , Michael Christopher Scaife , Jeffrey P. Harris
发明人： Jay Lichter , Andrew M. Trammel , Fabrice Piu , Luis A. Dellamary , Qiang Ye , Carl Lebel , Michael Christopher Scaife , Jeffrey P. Harris
IPC分类号： A61K9/00 , A61K9/06 , A61K9/14
CPC分类号： A61K9/0046 , A61K9/06 , A61K9/127 , A61K9/14 , A61K9/16 , A61K31/05 , A61K31/13 , A61K31/137 , A61K31/325 , A61K31/43 , A61K31/436 , A61K31/519 , A61K31/5513 , A61K31/5517 , A61K38/18 , A61K38/1808 , A61K38/1825 , A61K38/185 , A61K38/1858 , A61K38/1883 , A61K47/14 , A61K47/18 , A61K47/32 , A61K47/38 , A61K2039/505 , C07K16/241 , C07K2317/21 , C07K2317/76
摘要： Disclosed herein are compositions and methods for the treatment of otic disorders with immunomodulating agents and auris pressure modulators. In these methods, the auris compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of the immunomodulating and/or auris pressure modulating compositions and formulations onto the auris media and/or auris interna target areas, or via perfusion into the auris media and/or auris interna structures.
摘要翻译：本文公开了用免疫调节剂和耳压调节剂治疗耳部疾病的组合物和方法。在这些方法中，通过将免疫调节和/或耳压调节组合物和制剂直接施用到耳朵介质和/或内耳目标区域上，或通过灌注到耳朵介质和/或耳内结构中。

4. 发明授权

US08496957B2 Controlled release auris sensory cell modulator compositions and methods for the treatment of otic disorders 有权
标题翻译：控制释放耳感觉细胞调节剂组合物和治疗耳部疾病的方法
公开(公告)号：US08496957B2
公开(公告)日：2013-07-30
申请号：US12504553
申请日：2009-07-16
申请人： Jay Lichter , Benedikt Vollrath , Sergio G. Duron , Carl Lebel , Fabrice Piu , Qiang Ye , Luis A. Dellamary , Andrew M. Trammel , Michael Christopher Scaife , Jeffrey P. Harris
发明人： Jay Lichter , Benedikt Vollrath , Sergio G. Duron , Carl Lebel , Fabrice Piu , Qiang Ye , Luis A. Dellamary , Andrew M. Trammel , Michael Christopher Scaife , Jeffrey P. Harris
IPC分类号： A61K9/14 , A61K31/47 , A61K31/517
CPC分类号： A61K31/517 , A61K9/0046 , A61K31/135 , A61K31/137 , A61K31/4535 , A61K31/47 , A61K47/10 , A61K47/32 , A61K47/34
摘要： Disclosed herein are methods for the treatment of otic diseases or conditions with intratympanic compositions and formulations of multiparticulate auris sensory cell modulating agent administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
摘要翻译：本文公开的方法是通过将这些组合物和制剂直接施用于灌注或通过灌注而经由鼓室内组合物和多颗粒耳感觉细胞调节剂的制剂局部施用于患有耳科疾病或病症的个体的耳科疾病或病症的方法目标耳结构。

5. 发明申请

US20090325938A1 CONTROLLED-RELEASE CNS MODULATING COMPOSITIONS AND METHODS FOR THE TREATMENT OF OTIC DISORDERS 审中-公开
标题翻译：控制释放中枢神经系统调节组合物和治疗情况的方法
公开(公告)号：US20090325938A1
公开(公告)日：2009-12-31
申请号：US12494156
申请日：2009-06-29
申请人： Jay Lichter , Benedikt Vollrath , Sergio G. Duron , Carl Lebel , Fabrice PIU , Qiang Ye , Luis A. Dellamary , Andrew M. Trammel , Michael Christopher Scaife , Jeffrey P. Harris
发明人： Jay Lichter , Benedikt Vollrath , Sergio G. Duron , Carl Lebel , Fabrice PIU , Qiang Ye , Luis A. Dellamary , Andrew M. Trammel , Michael Christopher Scaife , Jeffrey P. Harris
IPC分类号： A61K31/5517 , A61K31/5513 , A61K31/164
CPC分类号： A61K9/0046 , A61K9/06 , A61K31/00 , A61K31/167 , A61K31/195 , A61K31/197 , A61K31/5513 , A61K45/06 , A61K47/10 , A61K47/14 , A61K47/38 , A61K47/44 , A61K2300/00
摘要： Disclosed herein are compositions and methods for the treatment of otic disorders with CNS modulating agent compositions and compositions administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and compositions onto or via perfusion into the targeted auris structure(s).
摘要翻译：本文公开的是通过将CNS调节剂组合物和组合物局部施用于患有耳科疾病的个体，通过将这些组合物和组合物直接施用到或经由灌注到目标耳结构中来治疗耳部疾病的组合物和方法，。

6. 发明授权

US11377377B2 Horizontal-vertical drain board-flocculation vacuum preloading sediment treatment method 有权
公开(公告)号：US11377377B2
公开(公告)日：2022-07-05
申请号：US16910079
申请日：2020-06-24
申请人： Jun Wang , Hongtao Fu , Yuanqiang Cai , Peng Wang , Guohui Yuan , Jinqiang Jin , Haidong Xu , Zhengde Xia , Junfeng Ni , Ziyang Ggao , Qiang Ye , Youchang Lv , Zhi Guan , Ziwu Jiang , Zhijian Chen
发明人： Jun Wang , Hongtao Fu , Yuanqiang Cai , Peng Wang , Guohui Yuan , Jinqiang Jin , Haidong Xu , Zhengde Xia , Junfeng Ni , Ziyang Ggao , Qiang Ye , Youchang Lv , Zhi Guan , Ziwu Jiang , Zhijian Chen
IPC分类号： B01D35/06 , C02F1/52 , C02F1/463 , C02F1/00
摘要： A horizontal-vertical drain board-flocculation vacuum preloading sediment treatment method, including (1) electro-osmotic electrodes disposed on the top and bottom of each reinforcing bar of the reinforced frame; (2) after the sediment is blown to the bottommost layer of vacuum preloading tank, the support is fitted over each reinforced frame, and the clips are fastened; (3) the transverse drain board passes through the support, one end of transverse drain board is connected to a curved tube; (4) repeat Step 2 and Step 3 until the sediment is blown to the surface layer of vacuum preloading tank; (5) a vertical drain board is arranged vertically between two adjacent rows of reinforced frames; (6) the curved tube is connected to the first junction block through the second junction block, and then the geotextile and sealing film are laid, the vacuum pump and power supply are switched on at last.

7. 发明申请

US20210403351A1 HORIZONTAL-VERTICAL DRAIN BOARD-FLOCCULATION VACUUM PRELOADING SEDIMENT TREATMENT METHOD 有权
公开(公告)号：US20210403351A1
公开(公告)日：2021-12-30
申请号：US16910079
申请日：2020-06-24
申请人： Jun Wang , Hongtao Fu , Yuanqiang Cai , Peng Wang , Guohui Yuan , Jinqiang Jin , Haidong Xu , Zhengde Xia , Junfeng Ni , Ziyang Ggao , Qiang Ye , Youchang Lv , Zhi Guan , Ziwu Jiang , Zhijian Chen
发明人： Jun Wang , Hongtao Fu , Yuanqiang Cai , Peng Wang , Guohui Yuan , Jinqiang Jin , Haidong Xu , Zhengde Xia , Junfeng Ni , Ziyang Ggao , Qiang Ye , Youchang Lv , Zhi Guan , Ziwu Jiang , Zhijian Chen
IPC分类号： C02F1/52 , C02F1/00 , C02F1/463
摘要： A horizontal-vertical drain board-flocculation vacuum preloading sediment treatment method, including (1) electro-osmotic electrodes disposed on the top and bottom of each reinforcing bar of the reinforced frame; (2) after the sediment is blown to the bottommost layer of vacuum preloading tank, the support is fitted over each reinforced frame, and the clips are fastened; (3) the transverse drain board passes through the support, one end of transverse drain board is connected to a curved tube; (4) repeat Step 2 and Step 3 until the sediment is blown to the surface layer of vacuum preloading tank; (5) a vertical drain board is arranged vertically between two adjacent rows of reinforced frames; (6) the curved tube is connected to the first junction block through the second junction block, and then the geotextile and sealing film are laid, the vacuum pump and power supply are switched on at last.

8. 发明授权

US08648119B2 Controlled release immunomodulator compositions and methods for the treatment of otic disorders 有权
标题翻译：控制释放免疫调节剂组合物和治疗耳部疾病的方法
公开(公告)号：US08648119B2
公开(公告)日：2014-02-11
申请号：US12472034
申请日：2009-05-26
申请人： Jay Lichter , Andrew M. Trammel , Fabrice Piu , Qiang Ye , Luis A. Dellamary , Carl Lebel , Jeffrey P. Harris
发明人： Jay Lichter , Andrew M. Trammel , Fabrice Piu , Qiang Ye , Luis A. Dellamary , Carl Lebel , Jeffrey P. Harris
IPC分类号： A61K47/30 , A61K38/00
CPC分类号： C07K16/241 , A61K9/0046 , A61K39/39591 , A61K47/34
摘要： Disclosed herein are compositions and methods for the treatment of otic disorders with immunomodulating agent compositions and formulations administered locally to an individual afflicted with an otic disorder, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
摘要翻译：本文公开了通过将免疫调节剂组合物和制剂局部施用于患有耳科疾病的个体，通过将这些组合物和制剂直接施用到或经由灌注到目标耳结构中来治疗耳部疾病的组合物和方法。

9. 发明申请

US20130045957A1 Prevention of and Recovery from Drug-Induced Ototoxicity 审中-公开
标题翻译：预防和恢复药物诱导的耳毒性
公开(公告)号：US20130045957A1
公开(公告)日：2013-02-21
申请号：US13398665
申请日：2012-02-16
申请人： Fabrice Piu , Qiang Ye , Luis Dellamary , Carl Lebel
发明人： Fabrice Piu , Qiang Ye , Luis Dellamary , Carl Lebel
IPC分类号： A61K31/573 , A61K31/4184 , A61P27/16 , A61K31/56
CPC分类号： A61K9/0046 , A61K9/10 , A61K31/24 , A61K31/282 , A61K31/416 , A61K31/4439 , A61K31/506 , A61K31/573 , A61K31/65 , A61K47/10 , A61P27/16 , A61K2300/00
摘要： Provided herein are methods for preventing and/or reducing the severity of drug induced ototoxicity. Provided herein are methods for recovery from hearing loss due to drug-induced ototoxicity.
摘要翻译：本文提供了用于预防和/或降低药物诱导的耳毒性的严重性的方法。本文提供了由于药物诱发的耳毒性而从听力损失中恢复的方法。

10. 发明授权

US08344041B2 Monomer for dental compositions 失效
标题翻译：牙科用组合物单体
公开(公告)号：US08344041B2
公开(公告)日：2013-01-01
申请号：US12415180
申请日：2009-03-31
申请人： Jonggu Park , Paulette Spencer , Elizabeth Murphy Topp , Qiang Ye
发明人： Jonggu Park , Paulette Spencer , Elizabeth Murphy Topp , Qiang Ye
IPC分类号： C08G18/67 , A61K59/68 , G03F7/029 , C09K3/00
CPC分类号： A61K6/083 , A61K6/09 , C08F2/50 , C08L25/04 , C08L33/04 , C08L75/16
摘要： A novel monomer, 1,1,1-tri-[4-(methacryloxyethylaminocarbonyloxy)-phenyl]ethane (MPE) can be used in preparing dental compositions The MPE monomer can be combined into a dental adhesive with hydroxyethyl methacrylate (HEMA) and BisGMA (bisphenol A dimethacrylate). The MPE polymer can be polymerized with a photoinitiator system, such as a system that includes an iodonium salt. The iodonium salt can be diphenyliodonium hexafluorophosphate.
摘要翻译：新型单体1,1,1-三 - [4-（甲基丙烯酰氧基乙基氨基羰基氧基） - 苯基]乙烷（MPE）可用于制备牙科用组合物。MPE单体可以与甲基丙烯酸羟乙酯（HEMA）和BisGMA （双酚A二甲基丙烯酸酯）。 MPE聚合物可以用光引发剂体系聚合，例如包含碘鎓盐的体系。碘鎓盐可以是二苯基碘鎓六氟磷酸盐。

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