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1. 发明申请

US20040073131A1 Electrical impedance method and apparatus for detecting and diagnosing diseases 审中-公开
公开(公告)号：US20040073131A1
公开(公告)日：2004-04-15
申请号：US10705988
申请日：2003-11-13
申请人： Z-TECH (CANADA) INC.
发明人： Leslie W. Organ , Kenneth C. Smith , Reza Safaee-Rad , Milan Graovac , George P. Darmos , Ilya Gavrilov
IPC分类号： A61B005/05
CPC分类号： A61B5/0536 , A61B5/04085 , A61B2562/046
摘要： The present invention relates to an improved method and apparatus for detecting and diagnosing disease states in a living organism by using a plurality of electrical impedance measurements. In particular, the invention provides for an improved electrode array for diagnosing the presence of a disease state in the human breast, and discloses a method of application of the array to the breast that ensures that the multiplicity of impedance measurements obtained from a first body part correspond as precisely and reproducibly as possible to the multiplicity of impedance measurements that are obtained from another, homologous, second body part. A number of diagnostic methods based on homologous electrical difference analysis are disclosed, including the calculation of a number of metrics used to indicate disease states by comparison with pre-established threshold values, and the construction of a number of graphical displays for indicating the location of disease to a body part sector.

2. 发明申请

US20040210158A1 Electrical impedance method and apparatus for detecting and diagnosing diseases 审中-公开
公开(公告)号：US20040210158A1
公开(公告)日：2004-10-21
申请号：US10841565
申请日：2004-05-10
申请人： Z-TECH (CANADA) INC.
发明人： Leslie W. Organ , Kenneth C. Smith , Reza Safaee-Rad , Milan Graovac , George P. Darmos , Ilya Gavrilov
IPC分类号： A61B005/05
CPC分类号： A61B5/0536 , A61B5/04085 , A61B2562/046
摘要： The present invention relates to an improved method and apparatus for detecting and diagnosing disease states in a living organism by using a plurality of electrical impedance measurements. In particular, the invention provides for an improved electrode array for diagnosing the presence of a disease state in the human breast, and discloses a method of application of the array to the breast that ensures that the multiplicity of impedance measurements obtained from a first body part correspond as precisely and reproducibly as possible to the multiplicity of impedance measurements that are obtained from another, homologous, second body part. A number of diagnostic methods based on homologous electrical difference analysis are disclosed, including the calculation of a number of metrics used to indicate disease states by comparison with pre-established threshold values, and the construction of a number of graphical displays for indicating the location of disease to a body part sector.

3. 发明申请

US20040243019A1 Weighted gradient method and system for diagnosing disease 审中-公开
标题翻译：加权梯度法和诊断疾病系统
公开(公告)号：US20040243019A1
公开(公告)日：2004-12-02
申请号：US10806186
申请日：2004-03-23
申请人： Z-Tech (Canada) Inc.
发明人： Milan Graovac , Zoran Pavlovic
IPC分类号： A61B005/05
CPC分类号： A61B5/0531
摘要： A method for detecting and diagnosing disease states in a body part is described. The method starts with a preparatory step of modeling the body part as a grid of many finite elements, then calculating the effect of the electrical property of each finite element at any one of a plurality of electrodes on the periphery of the body part as a function of the position of the finite element within the grid. This is termed the weight (influence) of the element. With this baseline information, electrical impedance measurements made at the plurality of electrodes on the periphery of the body part can be used in a diagnostic module to calculate a Weighted Element Value (WEVal) for each element. In a preferred embodiment of invention, the difference in WEVal magnitude between corresponding elements of homologous body parts serves as an indicator of the presence of disease.
摘要翻译：描述了用于检测和诊断身体部位中的疾病状态的方法。该方法从将身体部分建模为许多有限元的网格的准备步骤开始，然后计算在身体部位的周边上的多个电极中的任一个上的每个有限元的电性质的影响作为一个功能的网格内有限元的位置。这被称为元件的重量（影响）。利用该基线信息，可以在诊断模块中使用在身体部位的周边上的多个电极处进行的电阻抗测量来计算每个元件的加权元素值（WEVal）。在本发明的优选实施方案中，同源体部分的相应元件之间的WEVal量值的差异用作疾病存在的指标。

4. 发明申请

US20040210157A1 Electrical impedance method and apparatus for detecting and diagnosing diseases 审中-公开
标题翻译：用于检测和诊断疾病的电阻抗方法和装置
公开(公告)号：US20040210157A1
公开(公告)日：2004-10-21
申请号：US10841552
申请日：2004-05-10
申请人： Z-TECH (CANADA) INC.
发明人： Leslie W. Organ , Kenneth C. Smith , Reza Safaee-Rad , Milan Graovac , George P. Darmos , Ilya Gavrilov
IPC分类号： A61B005/05
CPC分类号： A61B5/0536 , A61B5/04085 , A61B2562/046
摘要： The present invention relates to an improved method and apparatus for detecting and diagnosing disease states in a living organism by using a plurality of electrical impedance measurements. In particular, the invention provides for an improved electrode array for diagnosing the presence of a disease state in the human breast, and discloses a method of application of the array to the breast that ensures that the multiplicity of impedance measurements obtained from a first body part correspond as precisely and reproducibly as possible to the multiplicity of impedance measurements that are obtained from another, homologous, second body part. A number of diagnostic methods based on homologous electrical difference analysis are disclosed, including the calculation of a number of metrics used to indicate disease states by comparison with pre-established threshold values, and the construction of a number of graphical displays for indicating the location of disease to a body part sector.
摘要翻译：本发明涉及通过使用多个电阻抗测量来检测和诊断活体中疾病状态的改进方法和装置。特别地，本发明提供了用于诊断人乳房中疾病状态的改善的电极阵列，并且公开了将阵列应用于乳房的方法，其确保从第一身体部位获得的多个阻抗测量值尽可能精确地和可重复地对应于从另一个同源的第二身体部分获得的多个阻抗测量。公开了基于同源电差分析的许多诊断方法，包括通过与预先建立的阈值比较来计算用于指示疾病状态的多个度量，以及用于指示位置的多个图形显示器的构造疾病到身体部位。

5. 发明申请

US20040167422A1 Breast electrode array and method of analysis for detecting and diagnosing diseases 审中-公开
标题翻译：乳房电极阵列及其分析方法，用于检测和诊断疾病
公开(公告)号：US20040167422A1
公开(公告)日：2004-08-26
申请号：US10724357
申请日：2003-12-01
申请人： Z-Tech (Canada) Inc.
发明人： Leslie W. Organ , Reza Safaee-Rad , Milan Graovac , Kenneth Carless Smith , Joel Steven Ironstone
IPC分类号： A61B005/053
CPC分类号： A61B5/4312 , A61B5/053 , A61B5/061 , A61B2562/046
摘要： A breast electrode array and method of analysis for detecting and diagnosing diseases. In particular, the electrode array has a body, a plurality of flexible arms extending from the body, and a plurality of outer electrodes provided by the plurality of flexible arms, and a plurality of inner electrodes provided on at least one of the flexible arms and positioned partway between the body and the outer electrodes, and the outer electrodes and the inner electrodes are arranged on the arms to obtain impedance measurements between respective electrodes. Diagnostic methods based on homologous electrical difference analysis are also provided, utilizing the different topologies created by the inner and outer electrodes when taking impedance measurements.
摘要翻译：一种乳房电极阵列及其分析方法，用于检测和诊断疾病。特别地，电极阵列具有主体，从主体延伸的多个柔性臂以及由多个柔性臂设置的多个外部电极，以及多个内部电极，设置在至少一个柔性臂和位于主体和外部电极之间，并且外部电极和内部电极布置在臂上以获得各个电极之间的阻抗测量。还提供了基于同源电差分析的诊断方法，利用内外电极在进行阻抗测量时产生的不同拓扑结构。

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