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1. 发明授权

US5981183A Method for amplifying and detecting of target nucleic acid sequence using thermostable enzyme 失效
标题翻译：使用热稳定酶扩增和检测靶核酸序列的方法
公开(公告)号：US5981183A
公开(公告)日：1999-11-09
申请号：US821782
申请日：1997-03-20
申请人： Yutaka Takarada , Hiroaki Inoue , Shuji Shibata , Yoshihisa Kawamura
发明人： Yutaka Takarada , Hiroaki Inoue , Shuji Shibata , Yoshihisa Kawamura
IPC分类号： C12Q1/68 , C07H21/04 , C12P19/34
CPC分类号： C12Q1/6865
摘要： In a method for amplifying the specific nucleic acid sequence, a highly specific amplification which has low possibility of non-specific hybridization can be carried out. Highly stable reagents, the activities of which do not decrease in case of supply and storage, are also provided. Thermostable enzymes are used as RNA dependent DNA polymerase, DNA dependent DNA polymerase, DNA dependent RNA polymerase and ribonuclease H, which are required for the amplification system based on replicated RNA. Especially, it is preferable that a thermostable enzyme derived from Thermus thermophilus which has RNA dependent DNA polymerase activity, DNA dependent DNA polymerase activity and ribonuclease H activity, and thermostable DNA dependent RNA polymerase are used together. By this method, inactivation of enzymes are prevented by using thermostable enzymes, and the amplification can be carried out without sequential addition of enzymes.
摘要翻译：在扩增特异性核酸序列的方法中，可以进行非特异性杂交的可能性低的高度特异性扩增。还提供了稳定的试剂，其供应和储存的活性不降低。热稳定酶用作基于复制RNA的扩增系统所需的RNA依赖性DNA聚合酶，DNA依赖性DNA聚合酶，DNA依赖性RNA聚合酶和核糖核酸酶H。特别优选共同使用具有RNA依赖性DNA聚合酶活性，DNA依赖性DNA聚合酶活性和核糖核酸酶H活性的嗜热栖热菌的热稳定性酶和耐热性DNA依赖型RNA聚合酶。通过这种方法，通过使用热稳定酶来防止酶的失活，并且可以不依次加入酶进行扩增。

2. 发明授权

US06303306B1 Method for amplifying and detecting of target nucleic acid sequence using thermostable enzyme 有权
标题翻译：使用热稳定酶扩增和检测靶核酸序列的方法
公开(公告)号：US06303306B1
公开(公告)日：2001-10-16
申请号：US09292435
申请日：1999-04-15
申请人： Yutaka Takarada , Hiroaki Inoue , Shuji Shibata , Yoshihisa Kawamura
发明人： Yutaka Takarada , Hiroaki Inoue , Shuji Shibata , Yoshihisa Kawamura
IPC分类号： C12Q168
CPC分类号： C12Q1/6865 , C12Q2527/101
摘要： In a method for amplifying the specific nucleic acid sequence, a highly specific amplification which has low possibility of non-specific hybridization can be carried out. Highly stable reagents, the activities of which do not decrease in case of supply and storage, are also provided. Thermostable enzymes are used as RNA dependent DNA polymerase, DNA dependent DNA polymerase, DNA dependent RNA polymerase and ribonuclease H, which are required for the amplification system based on replicated RNA. Especially, it is preferable that a thermostable enzyme derived from Thermus thermophilus which has RNA dependent DNA polymerase activity, DNA dependent DNA polymerase activity and ribonuclease H activity, and thermostable DNA dependent RNA polymerase are used together. By this method, inactivation of enzymes are prevented by using thermostable enzymes, and the amplification can be carried out without sequential addition of enzymes.
摘要翻译：在扩增特异性核酸序列的方法中，可以进行非特异性杂交的可能性低的高度特异性扩增。还提供了稳定的试剂，其供应和储存的活性不降低。热稳定酶用作基于复制RNA的扩增系统所需的RNA依赖性DNA聚合酶，DNA依赖性DNA聚合酶，DNA依赖性RNA聚合酶和核糖核酸酶H。特别优选共同使用具有RNA依赖性DNA聚合酶活性，DNA依赖性DNA聚合酶活性和核糖核酸酶H活性的嗜热栖热菌的热稳定性酶和耐热性DNA依赖型RNA聚合酶。通过这种方法，通过使用热稳定酶来防止酶的失活，并且可以不依次加入酶进行扩增。

3. 发明授权

US06225065B1 Kit for amplifying nucleic acid 失效
标题翻译：用于扩增核酸的试剂盒
公开(公告)号：US06225065B1
公开(公告)日：2001-05-01
申请号：US09418027
申请日：1999-10-14
申请人： Masao Kitabayashi , Taku Arakawa , Hiroaki Inoue , Bunsei Kawakami , Yoshihisa Kawamura , Tadayuki Imanaka , Masahiro Takagi , Masaaki Morikawa
发明人： Masao Kitabayashi , Taku Arakawa , Hiroaki Inoue , Bunsei Kawakami , Yoshihisa Kawamura , Tadayuki Imanaka , Masahiro Takagi , Masaaki Morikawa
IPC分类号： C12Q168
CPC分类号： C12N9/1252 , C12Q1/686
摘要： A nucleic acid amplifying enzyme having a short reaction time and high fidelity is provided. The enzyme of this invention is a thermostable DNA polymerase having a nucleic acid extension rate of at least 30 bases per second and a 3′-5′ exonuclease activity. Also provided are a method and kit for amplifying nucleic acid.
摘要翻译：提供了具有短反应时间和高保真度的核酸扩增酶。本发明的酶是具有至少30个碱基/秒的核酸延伸速率和3'-5'核酸外切酶活性的热稳定的DNA聚合酶。还提供了用于扩增核酸的方法和试剂盒。

4. 发明授权

US6054301A Methods of amplification using a thermostable DNA polymerase from the hyperthermophilic archaeon strain KOD1 and reagent kit therefor 失效
标题翻译：使用来自超嗜热古细菌菌株KOD1的热稳定DNA聚合酶的扩增方法及其试剂盒
公开(公告)号：US6054301A
公开(公告)日：2000-04-25
申请号：US656005
申请日：1996-05-24
申请人： Masao Kitabayashi , Taku Arakawa , Hiroaki Inoue , Bunsei Kawakami , Yoshihisa Kawamura , Tadayuki Imanaka , Masahiro Takagi , Masaaki Morikawa
发明人： Masao Kitabayashi , Taku Arakawa , Hiroaki Inoue , Bunsei Kawakami , Yoshihisa Kawamura , Tadayuki Imanaka , Masahiro Takagi , Masaaki Morikawa
IPC分类号： C12N15/09 , C12N1/21 , C12N9/12 , C12N15/54 , C12P21/02 , C12P21/04 , C12Q1/68 , C12R1/01 , C12R1/19 , G01N33/53 , G01N33/566 , C12P19/34 , C07K15/00
CPC分类号： C12Q1/686 , C12N9/1252
摘要： A nucleic acid amplifying enzyme having a short reaction time and high fidelity is provided. The enzyme of this invention is a thermostable DNA polymerase having a nucleic acid extension rate of at least 30 bases per second and a 3'-5' exonuclease activity. Also provided are a method and kit for amplifying nucleic acid.
摘要翻译：提供了具有短反应时间和高保真度的核酸扩增酶。本发明的酶是具有至少30个碱基/秒的核酸延伸速率和3'-5'核酸外切酶活性的热稳定的DNA聚合酶。还提供了用于扩增核酸的方法和试剂盒。

5. 发明授权

US6033859A Thermostable DNA polymerase from a hyperthermophilic archaeon strain KOD1 失效
标题翻译：来自超嗜热古细菌菌株KOD1的热稳定DNA聚合酶
公开(公告)号：US6033859A
公开(公告)日：2000-03-07
申请号：US73354
申请日：1998-05-06
申请人： Masao Kitabayashi , Taku Arakawa , Hiroaki Inoue , Bunsei Kawakami , Yoshihisa Kawamura , Tadayuki Imanaka , Masahiro Takagi , Masaaki Morikawa
发明人： Masao Kitabayashi , Taku Arakawa , Hiroaki Inoue , Bunsei Kawakami , Yoshihisa Kawamura , Tadayuki Imanaka , Masahiro Takagi , Masaaki Morikawa
IPC分类号： C12N9/12 , C12Q1/68 , C12P19/34 , C07K14/00 , C12N9/00
CPC分类号： C12N9/1252 , C12Q1/686
摘要： A nucleic acid amplifying enzyme having a short reaction time and high fidelity is provided. The enzyme of this invention is a thermostable DNA polymerase having a nucleic acid extension rate of at least 30 bases per second and a 3'-5' exonuclease activity. Also provided are a method and kit for amplifying nucleic acid.
摘要翻译：提供了具有短反应时间和高保真度的核酸扩增酶。本发明的酶是具有至少30个碱基/秒的核酸延伸速率和3'-5'核酸外切酶活性的热稳定的DNA聚合酶。还提供了用于扩增核酸的方法和试剂盒。

6. 发明授权

US09372202B2 Packaged device 有权
标题翻译：打包装置
公开(公告)号：US09372202B2
公开(公告)日：2016-06-21
申请号：US13618643
申请日：2012-09-14
申请人： Hiroaki Inoue , Takashi Katsuki , Fumihiko Nakazawa
发明人： Hiroaki Inoue , Takashi Katsuki , Fumihiko Nakazawa
IPC分类号： H05K7/00 , G01P15/125 , B81C1/00 , G01C19/5719 , G01P1/02 , G01P15/08 , H01L21/768 , H01L23/48
CPC分类号： G01P15/125 , B81C1/00301 , G01C19/5719 , G01P1/023 , G01P15/0802 , H01L21/76898 , H01L23/481 , H01L2924/0002 , Y10T29/49128 , H01L2924/00
摘要： A packaged device of one embodiment includes a device layer section, and first and second packaging members. The device layer section is one where a movable microdevice including a movable part and a terminal part is formed. The first packaging member is joined to the device layer section, and includes a wiring region provided at a position corresponding to the terminal part and a conductive plug extending through the wiring region. The second packaging member is joined to a side of the device layer section opposite the first packaging member.
摘要翻译：一个实施例的包装装置包括装置层部分，以及第一和第二包装部件。装置层部是形成有可动部和端子部的可动微型装置的部分。第一包装部件连接到器件层部分，并且包括设置在与端子部分相对应的位置处的布线区域和延伸穿过布线区域的导电插塞。第二包装部件与第一包装部件相对的装置层部分的一侧连接。

7. 发明授权

US09032421B2 Computation device and computation execution method 有权
标题翻译：计算设备和计算执行方法
公开(公告)号：US09032421B2
公开(公告)日：2015-05-12
申请号：US13985788
申请日：2011-10-21
申请人： Hiroaki Inoue , Takashi Takenaka
发明人： Hiroaki Inoue , Takashi Takenaka
IPC分类号： G06F13/00 , G06F9/54 , G06F7/00
CPC分类号： G06F9/542 , G06F7/00 , G06F17/30985
摘要： A computation device includes a data path element (300) including a function processing unit (4000) that executes a computation specified in a function using input data included in an event (1000) as an argument; and a control path element (2000) that detects the event (1000) by use of a return value (ret) of the function. The function processing unit (4000) includes a data calculation unit (4001) that executes a computation and outputs a first result (d0); and a control comparison unit (4002) that outputs, to the control path element (2000), a result of comparison between the input data and data for specifying the event (1000), as the return value (ret).
摘要翻译：计算装置包括数据路径元素（300），该数据路径元素（300）包括功能处理单元（4000），其使用包括在事件（1000）中的输入数据作为参数来执行在功能中指定的计算; 以及通过使用函数的返回值（ret）来检测事件（1000）的控制路径元素（2000）。功能处理单元（4000）包括执行计算并输出第一结果（d0）的数据计算单元（4001）。以及将所述输入数据和用于指定所述事件的数据（1000）的比较结果作为所述返回值（ret）输出到所述控制路径要素（2000）的控制比较部（4002）。

8. 发明授权

US09007708B2 Magnetic disk apparatus and data refresh method 有权
标题翻译：磁盘装置和数据刷新方法
公开(公告)号：US09007708B2
公开(公告)日：2015-04-14
申请号：US13563486
申请日：2012-07-31
申请人： Hiroaki Inoue
发明人： Hiroaki Inoue
IPC分类号： G11B27/36 , G11B5/012 , G11B5/09 , G11B20/10 , G11B20/18
CPC分类号： G11B20/1879 , G11B5/012 , G11B5/09 , G11B20/10009
摘要： According to at least one embodiment, a magnetic disk apparatus includes a disk, a random number generator, a determination module, and a refresh module. The disk includes a plurality of tracks. A random number generator generates a random number within a range of N integers in accordance with writing to a first area of a first track of the plurality of tracks. A determination module determines whether the generated random number includes a predetermined number. A refresh module refreshes a second area of a second track near the first track based on a result of determination of the determination module. The second area corresponds to the first area.
摘要翻译：根据至少一个实施例，磁盘装置包括盘，随机数发生器，确定模块和刷新模块。盘包括多个轨道。随机数生成器根据写入多个轨道的第一轨道的第一区域而在N个整数的范围内生成随机数。确定模块确定所生成的随机数是否包括预定数目。基于确定模块的确定结果，刷新模块刷新靠近第一轨道的第二轨道的第二区域。第二区域对应于第一区域。

9. 发明授权

US08935510B2 System structuring method in multiprocessor system and switching execution environment by separating from or rejoining the primary execution environment 有权
标题翻译：多处理器系统中的系统结构化方法和通过分离或重新连接主要执行环境的切换执行环境
公开(公告)号：US08935510B2
公开(公告)日：2015-01-13
申请号：US12447513
申请日：2007-11-01
申请人： Hiroaki Inoue , Junji Sakai , Tsuyoshi Abe , Masato Edahiro
发明人： Hiroaki Inoue , Junji Sakai , Tsuyoshi Abe , Masato Edahiro
IPC分类号： G06F15/80 , G06F9/50 , H04L29/08 , G06F9/44
CPC分类号： G06F9/5077 , G06F9/4405 , H04L29/08144 , H04L67/34
摘要： For flexibly setting up an execution environment according to contents of processing to be executed while taking stability or a security level into consideration, the multiple processor system includes the execution environment main control unit 10 which determines CPU assignment at the time of deciding CPU assignment, the execution environment sub control unit 20 which controls starting, stopping and switching of an execution environment according to an instruction from the execution environment main control unit 10 to synchronize with the execution environment main control unit 10, and the execution environment management unit 30 which receives input of management information or reference refusal information of shared resources for each CPU 4 or each execution environment 100 to separate the execution environment main control unit 10 from the execution environment sub control units 20a through 20n, or the execution environment sub control units 20a through 20n from each other.
摘要翻译：为了在考虑到稳定性或安全级别的同时根据要执行的处理的内容灵活地设置执行环境，多处理器系统包括确定CPU分配时的CPU分配的执行环境主控制单元10，执行环境子控制单元20，其根据来自执行环境主控制单元10的指令来控制执行环境的启动，停止和切换，以与执行环境主控制单元10同步;以及执行环境管理单元30，其接收输入对于每个CPU 4或每个执行环境100的共享资源的管理信息或参考拒绝信息，以将执行环境主控制单元10与执行环境子控制单元20a至20n或执行环境子控制单元20a至20n分离彼此。

10. 发明授权

US08872537B2 Semiconductor integrated circuit, circuit testing system, circuit testing unit, and circuit test method 有权
标题翻译：半导体集成电路，电路测试系统，电路测试单元和电路测试方法
公开(公告)号：US08872537B2
公开(公告)日：2014-10-28
申请号：US13256583
申请日：2010-04-09
申请人： Hiroaki Inoue
发明人： Hiroaki Inoue
IPC分类号： G01R31/02 , G01R31/3187 , G01R31/317
CPC分类号： G01R31/3187 , G01R31/3172
摘要： This invention has an object of providing a semiconductor integrated circuit enabling further reduction of the number of test terminals without depending on a compression/expansion technique alone. The semiconductor integrated circuit of the invention is connected to a terminal group used to exchange test information of a circuit to be tested, and comprises a utilization device which utilizes, when reading a test result, a terminal subgroup of the terminal group, which is not used to transmit information required to read the test result, to receive the test result from the circuit to be tested.
摘要翻译：本发明的目的是提供一种半导体集成电路，其能够进一步减少测试终端的数量而不依赖于压缩/扩展技术。本发明的半导体集成电路连接到用于交换被测电路的测试信息的终端组，并且包括利用装置，其在读取测试结果时使用不是终端组的终端子组用于传输读取测试结果所需的信息，从被测电路接收测试结果。

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