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    • 1. 发明申请
    • AUTOMATIC ANALYZER
    • 自动分析仪
    • US20090222213A1
    • 2009-09-03
    • US12388845
    • 2009-02-19
    • Yuko HAMAZUMITomonori MimuraYuki Fukuyama
    • Yuko HAMAZUMITomonori MimuraYuki Fukuyama
    • G01N33/48G06F19/00
    • G01N35/00663G01N2035/00673
    • The present invention provides an index that makes it possible to use, in an automatic analyzer, an approximate expression based on a theoretical chemical reaction formula derived from reaction process data, and automatically check for apparatus abnormalities, reagent deteriorations, and improper accuracy control during each continuous or individual inspection.Reaction process data, which is measured when the automatic analyzer determines the relationship between reaction absorbance and time, is approximated to ABS=A0+A1 (1−e−kt) by the least-squares method. The resulting reaction start point absorbance A0, final reaction absorbance A1, reaction rate constant k, and residual error, which is the aggregate sum of differences between approximate values and measured values, are then used as the index of reaction status.
    • 本发明提供一种能够在自动分析装置中使用基于从反应过程数据导出的理论化学反应式的近似表达式的指标,并且可以自动检查装置异常,试剂恶化和每次检测中的不正确的精度控制 连续或个别检查。 当自动分析仪确定反应吸光度和时间之间的关系时测量的反应过程数据通过最小二乘法近似为ABS = A0 + A1(1-e-kt)。 然后将所得到的反应起点吸光度A0,最终反应吸光度A1,反应速率常数k和剩余误​​差(即近似值和测量值之间的差值的总和)用作反应状态的指标。
    • 2. 发明申请
    • METHOD FOR ASSISTING JUDGMENT OF ABNORMALITY OF REACTION PROCESS DATA AND AUTOMATIC ANALYZER
    • 协助反应过程数据异常判断的方法和自动分析仪
    • US20110125415A1
    • 2011-05-26
    • US12995219
    • 2009-05-28
    • Satoshi MitsuyamaYuki FukuyamaHidekatsu TakadaHideyuki BanTomonori Mimura
    • Satoshi MitsuyamaYuki FukuyamaHidekatsu TakadaHideyuki BanTomonori Mimura
    • G06F19/00G01N35/00G01N21/00
    • G01N21/77G01N21/272G01N21/78G01N35/00603G01N2035/0097
    • In the event of a suspected abnormality in the device, sample or reagent, a laboratory technician had to examine the abnormal reaction process data item by item, and infer the cause of the abnormality, which took effort and time in some cases. Abnormality judgment is assisted using: indicator computation means that computes an indicator indicating a feature parameter of a given waveform by applying a pre-defined evaluation formula to time series data of photometric values; relative indicator computation means that computes a value indicating a relationship of the indicator of target data to the indicator computed in the past; and indicator display means that simultaneously displays a value computed by the indicator computation means and the value computed by the relative indicator computation means. According to the present method, which is a method for assisting judgment of abnormality wherein a feature parameter of a given absorbance change is computed, it can be made easier to find certain abnormalities, and it becomes possible to attain more efficient device maintenance and improved device reliability without the addition of any new parts.
    • 如果装置,样品或试剂中有疑似异常,实验室技术人员必须逐项检查异常反应过程数据,并推断异常的原因,在某些情况下花费时间和精力。 协助使用以下方式辅助异常判断:指标计算装置,通过对光度值的时间序列数据应用预定义的评估公式来计算指示给定波形的特征参数的指标; 相对指标计算是指计算出目标数据指标与过去计算出的指标的关系的值; 指示符显示装置,同时显示由指标计算装置计算的值和由相关指标计算装置计算的值。 根据本方法,其是计算给定吸光度变化的特征参数的异常判断方法,可以更容易地发现某些异常,并且可以实现更有效的装置维护和改进装置 可靠性无需添加任何新零件。
    • 3. 发明授权
    • Method for assisting judgment of abnormality of reaction process data and automatic analyzer
    • 协助判断反应过程数据异常和自动分析仪的方法
    • US09217712B2
    • 2015-12-22
    • US12995219
    • 2009-05-28
    • Satoshi MitsuyamaYuki FukuyamaHidekatsu TakadaHideyuki BanTomonori Mimura
    • Satoshi MitsuyamaYuki FukuyamaHidekatsu TakadaHideyuki BanTomonori Mimura
    • G06F19/00G01N35/00G01N21/00G01N21/77
    • G01N21/77G01N21/272G01N21/78G01N35/00603G01N2035/0097
    • In the event of a suspected abnormality in the device, sample or reagent, a laboratory technician had to examine the abnormal reaction process data item by item, and infer the cause of the abnormality, which took effort and time in some cases. Abnormality judgment is assisted using: indicator computation means that computes an indicator indicating a feature parameter of a given waveform by applying a pre-defined evaluation formula to time series data of photometric values; relative indicator computation means that computes a value indicating a relationship of the indicator of target data to the indicator computed in the past; and indicator display means that simultaneously displays a value computed by the indicator computation means and the value computed by the relative indicator computation means. According to the present method, which is a method for assisting judgment of abnormality wherein a feature parameter of a given absorbance change is computed, it can be made easier to find certain abnormalities, and it becomes possible to attain more efficient device maintenance and improved device reliability without the addition of any new parts.
    • 如果装置,样品或试剂中有疑似异常,实验室技术人员必须逐项检查异常反应过程数据,并推断异常的原因,在某些情况下花费时间和精力。 协助使用以下方式辅助异常判断:指标计算装置,通过对光度值的时间序列数据应用预定义的评估公式来计算指示给定波形的特征参数的指标; 相对指标计算是指计算出目标数据指标与过去计算出的指标的关系的值; 指示符显示装置,同时显示由指标计算装置计算的值和由相关指标计算装置计算的值。 根据本方法,其是计算给定吸光度变化的特征参数的异常判断方法,可以更容易地发现某些异常,并且可以实现更有效的装置维护和改进装置 可靠性无需添加任何新零件。