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1. 发明授权

US08008306B2 Quinoline compounds 有权
标题翻译：喹啉化合物
公开(公告)号：US08008306B2
公开(公告)日：2011-08-30
申请号：US12430397
申请日：2009-04-27
申请人： Minoru Koura , Ayumu Okuda , Takayuki Matsuda , Yuki Yamaguchi , Hisashi Sumida , Sayaka Kurobuchi , Yuichiro Watanabe , Takashi Enomoto , Kimiyuki Shibuya
发明人： Minoru Koura , Ayumu Okuda , Takayuki Matsuda , Yuki Yamaguchi , Hisashi Sumida , Sayaka Kurobuchi , Yuichiro Watanabe , Takashi Enomoto , Kimiyuki Shibuya
IPC分类号： C07D215/12 , C07D215/233 , C07D241/40 , A61K31/4709 , A61K31/498
CPC分类号： C07D401/14 , C07D401/12 , C07D405/14
摘要： To provide a novel LXRβ agonist that is useful as a preventative and/or therapeutic agent for atherosclerosis; arteriosclerosis such as those resulting from diabetes; dyslipidemia; hypercholesterolemia; lipid-related diseases; inflammatory diseases that are caused by inflammatory cytokines; skin diseases such as allergic skin diseases; diabetes; or Alzheimer's disease.A quinoline compound represented by the following general formula (1) or salt thereof, or their solvate.
摘要翻译：提供一种新颖的LXR＆bgr 可用作动脉粥样硬化的预防和/或治疗剂的激动剂; 动脉硬化，如糖尿病引起的; 血脂异常高胆固醇血症脂质相关疾病; 由炎性细胞因子引起的炎性疾病; 皮肤病如过敏性皮肤病; 糖尿病; 或阿尔茨海默病。由以下通式（1）表示的喹啉化合物或其盐或其溶剂化物。

2. 发明授权

US08153634B2 Carbinol derivatives having cyclic linker 有权
标题翻译：具有环状接头的甲醇衍生物
公开(公告)号：US08153634B2
公开(公告)日：2012-04-10
申请号：US12474799
申请日：2009-05-29
申请人： Yuki Yamaguchi , Minoru Koura , Sayaka Kurobuchi , Takayuki Matsuda , Ayumu Okuda , Hisashi Sumida , Yuichiro Watanabe , Takashi Enomoto , Kimiyuki Shibuya
发明人： Yuki Yamaguchi , Minoru Koura , Sayaka Kurobuchi , Takayuki Matsuda , Ayumu Okuda , Hisashi Sumida , Yuichiro Watanabe , Takashi Enomoto , Kimiyuki Shibuya
IPC分类号： A61K31/4166 , A61K31/4178 , A61K31/4355 , A61K31/4439 , A61K31/497 , A61K31/501 , A61K31/506 , C07D401/02 , C07D401/06 , C07D405/14 , C07D405/02 , C07D491/048 , C07D233/72 , C07D403/02 , C07D403/06
CPC分类号： C07D233/72 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D405/04 , C07D405/14 , C07D491/048
摘要： [Object] To provide a novel LXRβ agonist that is useful as a preventative and/or therapeutic agent for atherosclerosis; arteriosclerosis such as those resulting from diabetes; dyslipidemia; hypercholesterolemia; lipid-related diseases; inflammatory diseases that are caused by inflammatory cytokines; skin diseases such as allergic skin diseases; diabetes; or Alzheimer's disease.[Solving Means] A carbinol compound represented by the following general formula (I) or salt thereof, or their solvate.
摘要翻译： [目的]提供一种新型的LXR＆bgr; 可用作动脉粥样硬化的预防和/或治疗剂的激动剂; 动脉硬化，如糖尿病引起的; 血脂异常高胆固醇血症脂质相关疾病; 由炎性细胞因子引起的炎性疾病; 皮肤病如过敏性皮肤病; 糖尿病; 或阿尔茨海默病。 [解决方案]由以下通式（I）表示的甲醇化合物或其盐或其溶剂化物。

3. 发明申请

US20100048610A1 CARBINOL DERIVATIVES HAVING CYCLIC LINKER 有权
标题翻译：具有循环链接器的卡宾诺衍生物
公开(公告)号：US20100048610A1
公开(公告)日：2010-02-25
申请号：US12474799
申请日：2009-05-29
申请人： Yuki Yamaguchi , Minoru Koura , Sayaka Kurobuchi , Takayuki Matsuda , Ayumu Okuda , Hisashi Sumida , Yuuichirou Watanabe , Takashi Enomoto , Kimiyuki Shibuya
发明人： Yuki Yamaguchi , Minoru Koura , Sayaka Kurobuchi , Takayuki Matsuda , Ayumu Okuda , Hisashi Sumida , Yuuichirou Watanabe , Takashi Enomoto , Kimiyuki Shibuya
IPC分类号： A61K31/436 , C07D401/06 , A61K31/4439 , C07D491/056
CPC分类号： C07D233/72 , C07D401/04 , C07D401/06 , C07D401/12 , C07D401/14 , C07D403/04 , C07D405/04 , C07D405/14 , C07D491/048
摘要： [Object] To provide a novel LXRβ agonist that is useful as a preventative and/or therapeutic agent for atherosclerosis; arteriosclerosis such as those resulting from diabetes; dyslipidemia; hypercholesterolemia; lipid-related diseases; inflammatory diseases that are caused by inflammatory cytokines; skin diseases such as allergic skin diseases; diabetes; or Alzheimer's disease.[Solving Means] A carbinol compound represented by the following general formula (I) or salt thereof, or their solvate.
摘要翻译： [目的]提供一种新型的LXR＆bgr; 可用作动脉粥样硬化的预防和/或治疗剂的激动剂; 动脉硬化，如糖尿病引起的; 血脂异常高胆固醇血症脂质相关疾病; 由炎性细胞因子引起的炎性疾病; 皮肤病如过敏性皮肤病; 糖尿病; 或阿尔茨海默病。 [解决方案]由以下通式（I）表示的甲醇化合物或其盐或其溶剂化物。

4. 发明申请

US20100280013A1 CARBINOL DERIVATIVES HAVING HETEROCYCLIC LINKER 有权
标题翻译：具有杂环连接体的卡宾诺衍生物
公开(公告)号：US20100280013A1
公开(公告)日：2010-11-04
申请号：US12769104
申请日：2010-04-28
申请人： Minoru Koura , Hisashi Sumida , Sayaka Kurobuchi , Takayuki Matsuda , Yuichiro Watanabe , Takashi Enomoto , Kimiyuki Shibuya , Sumiko Kurobuchi
发明人： Minoru Koura , Hisashi Sumida , Sayaka Kurobuchi , Takayuki Matsuda , Yuichiro Watanabe , Takashi Enomoto , Kimiyuki Shibuya , Sumiko Kurobuchi
IPC分类号： A61K31/551 , C07D401/14 , C07D403/06 , C07D407/14 , A61P3/10 , A61P25/28 , A61P3/06 , A61P29/00 , A61K31/496 , A61P7/00 , A61P9/10 , A61P17/00
CPC分类号： C07D233/78 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/06 , C07D405/04 , C07D405/14 , C07D491/04
摘要： [Object] It is to provide a novel LXRβ agonist useful as a preventative and/or therapeutic agent for atherosclerosis; arteriosclerosis such as those resulting from diabetes; dyslipidemia; hypercholesterolemia; lipid-related diseases; inflammatory diseases that are caused by inflammatory cytokines; skin diseases such as allergic skin diseases; diabetes; or Alzheimer's disease.[Solving Means] A carbinol compound represented by the following general formula (I) or salt thereof, or their solvate: (wherein, each V and W independently show N or C—R7; each X and Y independently show CH2, C═O, SO2, etc; Z shows CH or N; each R1, R2 and R7 independently show a hydrogen atom, C1-8 alkyl group, etc.; R3 shows C1-8 alkyl group; R4 shows an optionally substituted C6-10 aryl group or an optionally substituted 5- to 11-membered heterocyclic group; R5 and R6 show a hydrogen atom, etc.; L shows a C1-8 alkyl chain optionally substituted with an oxo group, etc.; and n shows any integer of 0 to 2.)
摘要翻译： [对象]提供一个新颖的LXR＆bgr; 可用作动脉粥样硬化的预防和/或治疗剂的激动剂; 动脉硬化，如糖尿病引起的; 血脂异常高胆固醇血症脂质相关疾病; 由炎性细胞因子引起的炎性疾病; 皮肤病如过敏性皮肤病; 糖尿病; 或阿尔茨海默病。 [解决方案]由以下通式（I）表示的甲醇化合物或其盐或其溶剂化物：（其中，V和W各自独立地表示N或C-R7; X和Y各自独立地表示CH 2，C = O ，SO2等; Z表示CH或N;每个R1，R2和R7独立地表示氢原子，C1-8烷基等; R3表示C1-8烷基; R4表示任选取代的C6-10芳基或任选取代的5至11元杂环基; R 5和R 6表示氢原子等; L表示任选被氧代基等取代的C 1-8烷基链; n表示0〜 2.）

5. 发明授权

US08551985B2 Carbinol derivatives having heterocyclic linker 有权
标题翻译：具有杂环连接体的甲醇衍生物
公开(公告)号：US08551985B2
公开(公告)日：2013-10-08
申请号：US12769104
申请日：2010-04-28
申请人： Minoru Koura , Hisashi Sumida , Takayuki Matsuda , Yuichiro Watanabe , Takashi Enomoto , Kimiyuki Shibuya , Sumiko Kurobuchi
发明人： Minoru Koura , Hisashi Sumida , Sayaka Kurobuchi , Takayuki Matsuda , Yuichiro Watanabe , Takashi Enomoto , Kimiyuki Shibuya
IPC分类号： A61K31/496 , A61K31/551 , C07D233/72 , C07D401/04 , C07D401/14 , C07D405/04 , C07D405/14 , C07D491/048 , C07D491/056
CPC分类号： C07D233/78 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/06 , C07D405/04 , C07D405/14 , C07D491/04
摘要： [Object]It is to provide a novel LXRβ agonist useful as a preventative and/or therapeutic agent for atherosclerosis; arteriosclerosis such as those resulting from diabetes; dyslipidemia; hypercholesterolemia; lipid-related diseases; inflammatory diseases that are caused by inflammatory cytokines; skin diseases such as allergic skin diseases; diabetes; or Alzheimer's disease.[Solving Means]A carbinol compound represented by the following general formula (I) or salt thereof, or their solvate: (wherein, each V and W independently show N or C—R7; each X and Y independently show CH2, C═O, SO2, etc; Z shows CH or N; each R1, R2 and R7 independently show a hydrogen atom, C1-8 alkyl group, etc.; R3 shows C1-8 alkyl group; R4 shows an optionally substituted C6-10 aryl group or an optionally substituted 5- to 11-membered heterocyclic group; R5 and R6 show a hydrogen atom, etc.; L shows a C1-8 alkyl chain optionally substituted with an oxo group, etc.; and n shows any integer of 0 to 2.)
摘要翻译：本发明提供可用作动脉粥样硬化的预防和/或治疗剂的新型LXRbeta激动剂; 动脉硬化，如糖尿病引起的; 血脂异常高胆固醇血症脂质相关疾病; 由炎性细胞因子引起的炎性疾病; 皮肤病如过敏性皮肤病; 糖尿病; 或阿尔茨海默病。 [解决方案]由以下通式（I）表示的甲醇化合物或其盐或其溶剂化物：（其中，V和W各自独立地表示N或C-R7; X和Y各自独立地表示CH 2，C = O ，SO2等; Z表示CH或N;每个R1，R2和R7独立地表示氢原子，C1-8烷基等; R3表示C1-8烷基; R4表示任选取代的C6-10芳基或任选取代的5至11元杂环基; R 5和R 6表示氢原子等; L表示任选被氧代基等取代的C 1-8烷基链; n表示0〜 2.）

6. 发明授权

US08659841B2 Superwide-angle lens system 有权
标题翻译：超广角镜头系统
公开(公告)号：US08659841B2
公开(公告)日：2014-02-25
申请号：US13570389
申请日：2012-08-09
申请人： Takashi Enomoto
发明人： Takashi Enomoto
IPC分类号： G02B13/04 , G02B9/10
CPC分类号： G02B13/06
摘要： A superwide-angle lens system includes a negative first lens group, an aperture diaphragm, and a positive second lens group. The first lens group includes two negative meniscus lens elements, and a positive lens element. The second lens group includes a cemented lens having negative and positive lens elements; and a positive lens element. The following conditions (1) and (2) are satisfied: −1.45
摘要翻译：超广角镜头系统包括负第一透镜组，孔径光阑和正第二透镜组。第一透镜组包括两个负弯月透镜元件和正透镜元件。第二透镜组包括具有负透镜和正透镜元件的胶合透镜; 和正透镜元件。满足以下条件（1）和（2）：-1.45

7. 发明授权

US08501628B2 Differential metal gate etching process 有权
标题翻译：差分金属栅极蚀刻工艺
公开(公告)号：US08501628B2
公开(公告)日：2013-08-06
申请号：US12729538
申请日：2010-03-23
申请人： Vinh Hoang Luong , Hiroyuki Takahashi , Akiteru Ko , Asao Yamashita , Vaidya Bharadwaj , Takashi Enomoto , Daniel J. Prager
发明人： Vinh Hoang Luong , Hiroyuki Takahashi , Akiteru Ko , Asao Yamashita , Vaidya Bharadwaj , Takashi Enomoto , Daniel J. Prager
IPC分类号： H01L21/302
CPC分类号： H01L21/32136 , H01J37/32091 , H01J37/32165 , H01J37/3266 , H01L21/823437 , H01L21/823456
摘要： A method for etching a differential metal gate structure on a substrate is described. The differential metal gate structure includes a metal gate layer overlying a high dielectric constant (high-k) dielectric layer, wherein the metal gate layer comprises a different thickness at different regions on the substrate. The metal gate layer is patterned by using a plasma etching process, wherein at least one etch step includes forming plasma using a halogen-containing gas and at least one etch step includes forming plasma using an additive gas having as atomic constituents C, H, and F.
摘要翻译：描述了蚀刻基板上的差分金属栅极结构的方法。差分金属栅极结构包括覆盖高介电常数（高k）电介质层的金属栅极层，其中金属栅极层在衬底上的不同区域包括不同的厚度。通过使用等离子体蚀刻工艺对金属栅极层进行构图，其中至少一个蚀刻步骤包括使用含卤素气体形成等离子体，并且至少一个蚀刻步骤包括使用具有原子成分C，H和 F。

8. 发明授权

US08496444B2 Water-lifting pump apparatus and method of controlling operation thereof 有权
标题翻译：抽水泵装置及其操作方法
公开(公告)号：US08496444B2
公开(公告)日：2013-07-30
申请号：US12967469
申请日：2010-12-14
申请人： Isamu Kamata , Shinji Suzuki , Hideki Kanno , Takashi Enomoto , Masahiro Kuramasu
发明人： Isamu Kamata , Shinji Suzuki , Hideki Kanno , Takashi Enomoto , Masahiro Kuramasu
IPC分类号： F04B35/04
CPC分类号： F04D15/0066 , F04D9/007 , F04D13/16 , F04D15/0022 , F04D29/669
摘要： A water-lifting pump apparatus which is free of a discharge valve and a check valve, is low in cost, and is capable of reducing vibration and noise due to a waterfall after the end of water pumping operation. The water-lifting pump apparatus has a suction tank (10), a discharge tank (20), a pump (30) for pumping water in the suction tank (10) into the discharge tank (20), and a discharge piping (50) connected to a discharge side of the pump, an actuator (60) for actuating the pump (50), a reverse flow preventing mechanism (80) for preventing a reverse flow of water pumped into the discharge tank (20) toward the discharge piping (50), and a back flow rate control (90) for controlling the flow rate of a waterfall falling from the discharge piping (50) into the suction tank (10) when pumping operation is finished.
摘要翻译：没有排气阀和止回阀的抽水泵装置成本低，并且能够在抽水操作结束后减少由瀑布引起的振动和噪音。抽水泵装置具有吸入箱（10），排放罐（20），用于将吸入箱（10）中的水排入排放罐（20）的泵（30）和排出管道（50））连接到泵的排出侧，用于致动泵（50）的致动器（60），用于防止泵送到排出罐（20）中的水朝向排出管道（50），以及用于在泵送操作结束时控制从排出管道（50）落入吸入箱（10）的瀑布的流量的回流量控制（90）。

9. 发明申请

US20120195748A1 VORTEX PREVENTION DEVICE AND DOUBLE SUCTION VERTICAL PUMP HAVING SUCH VORTEX PREVENTION DEVICE 有权
标题翻译： VORTEX预防装置和双重垂直垂直泵具有这种VORTEX预防装置
公开(公告)号：US20120195748A1
公开(公告)日：2012-08-02
申请号：US13498213
申请日：2010-09-24
申请人： Takashi Yamanaka , Dai Kudo , Shuichiro Honda , Takashi Enomoto
发明人： Takashi Yamanaka , Dai Kudo , Shuichiro Honda , Takashi Enomoto
IPC分类号： F04D29/00
CPC分类号： F04D13/08 , F04D1/006 , F04D29/4273 , F04D29/448 , F04D29/548 , F04D29/669 , F04D29/708
摘要： A vortex prevention device is capable of preventing creation of air entrained vortex and also provides a double suction vertical pump having such a vortex prevention device. The vortex prevention device is used in combination with the double suction vertical pump which is installed in an open channel and has an upper suction opening and a lower suction opening. The vortex prevention device includes a plate member as a vortex prevention structure arranged above the upper suction opening. The plate member is arranged away from the upper suction opening such that a passage is formed between the plate member and the upper suction opening.
摘要翻译：防涡流装置能够防止产生空气夹带的涡流，并且还提供具有这种防涡流装置的双吸立式泵。防涡流装置与安装在开放通道中的双吸立式泵组合使用，并具有上抽吸口和下抽吸口。防涡流装置包括布置在上吸入口上方的防涡旋结构的板构件。板构件远离上吸入口布置，使得在板构件和上吸入口之间形成通道。

10. 发明申请

US20120147480A1 ZOOM LENS SYSTEM 有权
标题翻译：变焦镜头系统
公开(公告)号：US20120147480A1
公开(公告)日：2012-06-14
申请号：US13391668
申请日：2010-08-13
申请人： Junichi Fujisaki , Takashi Enomoto , Tomoya Koga
发明人： Junichi Fujisaki , Takashi Enomoto , Tomoya Koga
IPC分类号： G02B15/14
CPC分类号： G02B15/177
摘要： The objective of the present invention is to provide a zoom lens system having an f-number of approximately 1.3 at the wide extremity, a half angle-of-view of 75 degrees, and a zoom ratio of approximately 3:1. The solution to this objective is to provide a zoom lens system including a first lens group, having a negative refractive power, a diaphragm, and a second lens group, having a positive refractive power, in that order from the object side; wherein the first lens group and the second lens group move in the optical axis direction so that the distance therebetween decreases upon zooming from the wide-angle extremity to the telephoto extremity,
摘要翻译：本发明的目的是提供一种变焦透镜系统，其在宽端具有约1.3的f数，75度的半视角和大约3:1的变焦比。该目的的解决方案是从物体侧依次提供具有正折光力的具有负折光力的第一透镜组，第二透镜组和第二透镜组的变焦透镜系统; 其中所述第一透镜组和所述第二透镜组在所述光轴方向上移动，使得在从所述广角端到远摄端的变焦时，所述第一透镜组和所述第二透镜组之间的距离减小，

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