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1. 发明授权

US08810116B2 Spark plug and method of manufacturing the same 有权
标题翻译：火花塞和制造方法相同
公开(公告)号：US08810116B2
公开(公告)日：2014-08-19
申请号：US13212668
申请日：2011-08-18
申请人： Yuji Kasuya , Masahiro Inoue
发明人： Yuji Kasuya , Masahiro Inoue
IPC分类号： H01T13/20
CPC分类号： H01T13/32 , H01T21/02
摘要： A buried portion (32B) buried from a junction target surface of a ground electrode (27) is provided in a noble metal tip (32). In a section, perpendicular to a central axis CL2 of the ground electrode (27), a large width portion (32W) is formed in the buried portion (32B), and a region between the junction target surface and a largest width region of the large width portion (32W) is formed into a shape which gradually increases in width, or into a shape having a region of the relevant shape and a constant width region. A region from the large width portion (32W) to a point of intersection P1, P2 is covered with a base material of the ground electrode (27) and a melt portion (35), and a thickness t1 (mm) of the noble metal tip (32) and a buried amount t2 (mm) satisfy 0.25≦t2/t1.
摘要翻译：在贵金属端头（32）上设有从接地电极（27）的接合靶表面埋设的埋入部（32B）。在垂直于接地电极（27）的中心轴线CL2的截面中，在埋入部分（32B）中形成大的宽度部分（32W），并且在接合靶表面和接合电极的最大宽度区域之间的区域大宽度部分（32W）形成为宽度逐渐增大的形状，或具有相关形状区域和恒定宽度区域的形状。从宽幅部（32W）到交点P1，P2的区域被接地电极（27）的基材和熔融部（35）覆盖，贵金属的厚度t1（mm）尖端（32）和埋入量t2（mm）满足0.25＆nlE; t2 / t1。

2. 发明授权

US07811556B2 Polymeric modifiers and pharmaceutical compositions 有权
标题翻译：聚合物改性剂和药物组合物
公开(公告)号：US07811556B2
公开(公告)日：2010-10-12
申请号：US11231963
申请日：2005-09-22
申请人： Yuji Kasuya , Masashi Honma
发明人： Yuji Kasuya , Masashi Honma
IPC分类号： A61K31/74
CPC分类号： C08L71/02 , A61K38/177 , A61K47/58 , A61K47/60 , C08F8/32 , C08F2216/1425 , C08L2203/02 , C08L2666/04 , A61K2300/00 , C08F8/12 , C08F222/06 , C08F8/44
摘要： A copolymer or a pharmacologically acceptable salt thereof is provided, which contains, as constitutional units, (a) one or more structural units of formula (I): wherein m is an integer of from 3 to 100, Alk represents alkyline, and R1 and R2 are the same or different and each represents hydrogen or optionally substituted alkyl, and (b) one or more structural units of formula (II): wherein R3 represents hydroxyl, optionally substituted alkoxy, optionally substituted aryloxy, or a group represented by the formula —NR4R5, wherein R4 and R5 are the same or different and each represents hydrogen or optionally substituted alkyl. There is further provided a pharmaceutical composition comprising said copolymer, a protein modifier comprising said copolymer, a complex of said copolymer with a protein, and method of preventing or treating diseases using said complex, use of said complex in the manufacture of a medicament for preventing or treating diseases and methods for the synthesis of said copolymers and said complexes.
摘要翻译：提供了一种共聚物或其药学上可接受的盐，其包含作为结构单元的（a）一种或多种式（I）的结构单元：其中m为3至100的整数，Alk表示烷基，R1和 R 2相同或不同，各自表示氢或任选取代的烷基，和（b）一种或多种式（II）的结构单元：其中R 3表示羟基，任选取代的烷氧基，任选取代的芳氧基或由式 -NR4R5，其中R4和R5相同或不同，并且各自表示氢或任选取代的烷基。还提供一种药物组合物，其包含所述共聚物，包含所述共聚物的蛋白质改性剂，所述共聚物与蛋白质的复合物，以及使用所述复合物预防或治疗疾病的方法，所述复合物在制备用于预防或治疗用于合成所述共聚物和所述复合物的疾病和方法。

3. 发明申请

US20120313503A1 SPARK PLUG 有权
标题翻译： SPARK插头
公开(公告)号：US20120313503A1
公开(公告)日：2012-12-13
申请号：US13578175
申请日：2010-11-26
申请人： Yuji Kasuya , Kenji Ban
发明人： Yuji Kasuya , Kenji Ban
IPC分类号： H01T13/20
CPC分类号： H01T13/39 , F02P13/00
摘要： A spark plug includes a ceramic insulator, a center electrode, a metallic shell, and a ground electrode. The center electrode has a shoulder portion at a forward end portion, which tapers forward with respect to the axial direction. A noble metal tip is joined to the forward end portion of the center electrode through a fusion zone. A spark discharge gap is formed between the noble metal tip and the ground electrode. The shortest distance between the fusion zone and a forward end surface of the noble metal tip is 0.8-1.2 mm. The outside diameter of the fusion zone as measured at a forward end of the fusion zone is smaller than that as measured at a rear end of the fusion zone. An acute angle θ1 formed by a straight line L1 and a straight line L2 satisfies the relational expression θ1≦72°.
摘要翻译：火花塞包括陶瓷绝缘体，中心电极，金属壳和接地电极。中心电极在前端部具有相对于轴向向前变细的肩部。贵金属端头通过熔接区域与中心电极的前端部接合。在贵金属端头和接地电极之间形成火花放电间隙。熔融区与贵金属端头的前端表面之间的最短距离为0.8-1.2mm。在熔融区的前端处测量的熔融区的外径小于在熔融区的后端测量的外径。由直线L1和直线L2形成的锐角和角度1满足关系式：1＆nlE; 72°。

4. 发明授权

US09318878B2 Spark plug with noble metal tip 有权
标题翻译：火花塞与贵金属尖端
公开(公告)号：US09318878B2
公开(公告)日：2016-04-19
申请号：US14235468
申请日：2012-05-15
申请人： Yuji Kasuya , Yoshikazu Kataoka
发明人： Yuji Kasuya , Yoshikazu Kataoka
IPC分类号： H01T13/06 , H01T13/32 , H01T13/39
CPC分类号： H01T13/06 , H01T13/32 , H01T13/39
摘要： In a section of a spark plug cut by a plane which passes through the center of gravity of the intermediate member and is in parallel with the facing direction between a center electrode and an extending portion of a ground electrode, a spark plug that satisfies the relational expression S1/(D1×H1)≧0.005, where S1 is the total area of nuggets, H1 is the height of the end surface of a noble metal tip from the disposition surface of an electrode base metal, and D1 is the maximum width of the noble metal tip.
摘要翻译：在由穿过中间构件的重心并与中心电极和接地电极的延伸部分之间的相对方向平行的平面切割的火花塞的一部分中，满足关系的火花塞表达式S1 /（D1×H1）≥0.005，其中S1是块的总面积，H1是贵金属尖端从电极母材的配置表面的端面的高度，D1是最大宽度贵金属尖端。

5. 发明授权

US08841826B2 Spark plug 有权
标题翻译：火花塞
公开(公告)号：US08841826B2
公开(公告)日：2014-09-23
申请号：US13578175
申请日：2010-11-26
申请人： Yuji Kasuya , Kenji Ban
发明人： Yuji Kasuya , Kenji Ban
IPC分类号： H01T13/20 , H01T13/39 , F02P13/00
CPC分类号： H01T13/39 , F02P13/00
摘要： A spark plug includes a ceramic insulator, a center electrode, a metallic shell, and a ground electrode. The center electrode has a shoulder portion at a forward end portion, which tapers forward with respect to the axial direction. A noble metal tip is joined to the forward end portion of the center electrode through a fusion zone. A spark discharge gap is formed between the noble metal tip and the ground electrode. The shortest distance between the fusion zone and a forward end surface of the noble metal tip is 0.8-1.2 mm. The outside diameter of the fusion zone as measured at a forward end of the fusion zone is smaller than that as measured at a rear end of the fusion zone. An acute angle θ1 formed by a straight line L1 and a straight line L2 satisfies the relational expression θ1≦72°.
摘要翻译：火花塞包括陶瓷绝缘体，中心电极，金属壳和接地电极。中心电极在前端部具有相对于轴向向前变细的肩部。贵金属端头通过熔接区域与中心电极的前端部接合。在贵金属端头和接地电极之间形成火花放电间隙。熔融区与贵金属端头的前端表面之间的最短距离为0.8-1.2mm。在熔融区的前端处测量的熔融区的外径小于在熔融区的后端测量的外径。由直线L1和直线L2形成的锐角和角度1满足关系式：1＆nlE; 72°。

6. 发明申请

US20110269942A1 ANTIBODIES MODIFIED WITH HYDROPHOBIC MOLECULE 审中-公开
标题翻译：用HYDROPHOBIC MOLECULLE修改的抗体
公开(公告)号：US20110269942A1
公开(公告)日：2011-11-03
申请号：US12672861
申请日：2008-08-04
申请人： Koji Morita , Takako Niwa , Yuji Kasuya , Kimihisa Ichikawa , Hiroko Yoshida
发明人： Koji Morita , Takako Niwa , Yuji Kasuya , Kimihisa Ichikawa , Hiroko Yoshida
IPC分类号： C07K16/28
CPC分类号： C07K16/2878 , A61K9/127 , A61K47/6913 , C07K2317/73
摘要： The present invention relates to an immunoliposome preparation or a hydrophobic molecule-modified antibody having a therapeutic effect on cancer, autoimmune disease, or inflammatory disease. Specifically, the present invention relates to an immunoliposome or a hydrophobic molecule-modified antibody comprising, as a constituent, an antibody capable of inducing the apoptosis of cells expressing a death domain-containing receptor.
摘要翻译：本发明涉及具有对癌症，自身免疫疾病或炎性疾病的治疗作用的免疫脂质体制剂或疏水性分子修饰抗体。具体地说，本发明涉及一种免疫脂质体或疏水性分子修饰抗体，其包含能够诱导表达含有死亡结构域的受体的细胞凋亡的抗体作为组分。

7. 发明申请

US20060062754A1 Polymeric modifiers and pharmaceutical compositions 有权
标题翻译：聚合物改性剂和药物组合物
公开(公告)号：US20060062754A1
公开(公告)日：2006-03-23
申请号：US11231963
申请日：2005-09-22
申请人： Yuji Kasuya , Masashi Honma
发明人： Yuji Kasuya , Masashi Honma
IPC分类号： A61K38/18
CPC分类号： C08L71/02 , A61K38/177 , A61K47/58 , A61K47/60 , C08F8/32 , C08F2216/1425 , C08L2203/02 , C08L2666/04 , A61K2300/00 , C08F8/12 , C08F222/06 , C08F8/44
摘要： A copolymer or a pharmacologically acceptable salt thereof is provided, which contains, as constitutional units, (a) one or more structural units of formula (I): wherein m is an integer of from 3 to 100, Alk represents alkyline, and R1 and R2 are the same or different and each represents hydrogen or optionally substituted alkyl, and (b) one or more structural units of formula (II): wherein R3 represents hydroxyl, optionally substituted alkoxy, optionally substituted aryloxy, or a group represented by the formula —NR4R5, wherein R4 and R5 are the same or different and each represents hydrogen or optionally substituted alkyl. There is further provided a pharmaceutical composition comprising said copolymer, a protein modifier comprising said copolymer, a complex of said copolymer with a protein, and method of preventing or treating diseases using said complex, use of said complex in the manufacture of a medicament for preventing or treating diseases and methods for the synthesis of said copolymers and said complexes.
摘要翻译：提供了一种共聚物或其药学上可接受的盐，其包含作为结构单元的（a）一种或多种式（I）的结构单元：其中m是3至100的整数，Alk表示烷基， SUP> 1和R 2相同或不同，各自表示氢或任选取代的烷基，和（b）一种或多种式（II）的结构单元：其中R ^{3表示羟基，任选取代的烷氧基，任选取代的芳氧基或由式-NR 4 R 5表示的基团，其中R 4 R 5和R 5相同或不同，各自表示氢或任选取代的烷基。还提供一种药物组合物，其包含所述共聚物，包含所述共聚物的蛋白质改性剂，所述共聚物与蛋白质的复合物，以及使用所述复合物预防或治疗疾病的方法，所述复合物在制备用于预防或治疗用于合成所述共聚物和所述复合物的疾病和方法。}

8. 发明申请

US20140152170A1 SPARK PLUG 有权
标题翻译： SPARK插头
公开(公告)号：US20140152170A1
公开(公告)日：2014-06-05
申请号：US14235468
申请日：2012-05-15
申请人： Yuji Kasuya , Yoshikazu Kataoka
发明人： Yuji Kasuya , Yoshikazu Kataoka
IPC分类号： H01T13/06
CPC分类号： H01T13/06 , H01T13/32 , H01T13/39
摘要： An object is to provide a technique for improving welding strength between an intermediate member and an electrode member. In a section of a spark plug cut by a plane which passes through the center of gravity of the intermediate member and is in parallel with the facing direction between a center electrode and an extending portion of a ground electrode, the spark plug satisfies the relational expression S1/(D1×H1)≧0.005, where S1 is the total area of nuggets, H1 is the height of the end surface of a noble metal tip from the disposition surface of an electrode base metal, and D1 is the maximum width of the noble metal tip.
摘要翻译：本发明的目的是提供一种用于提高中间构件和电极构件之间的焊接强度的技术。在由穿过中间构件的重心并与接地电极的中心电极和延伸部分之间的相对方向平行的平面切割的火花塞的一部分中，火花塞满足关系式 S1 /（D1×H1）≥0.005，其中S1是块的总面积，H1是贵金属端头从电极母材的配置表面的端面的高度，D1是贵金属尖端。

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