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    • 7. 发明授权
    • Acrylonitrile solutions of maleimides, method for preparation thereof,
and acrylonitrile based copolymers obtained by use of the solutions
    • 马来酰亚胺的丙烯腈溶液,其制备方法和使用该溶液得到的丙烯腈共聚物
    • US5993687A
    • 1999-11-30
    • US703709
    • 1996-08-27
    • Kazuo KishinoKinichi NakayamaFumioki ShimoyamaYuichi Kita
    • Kazuo KishinoKinichi NakayamaFumioki ShimoyamaYuichi Kita
    • C07C253/32C07C255/08C07D207/44C07D207/448C09K3/12
    • C07D207/448C07C253/32C07C255/08
    • An acrylonitrile solution of maleimide manifesting transparency, precluding coloration and opacification during the course of handling, and excelling in stability, a method for the preparation of the acrylonitrile solution, and an acrylonitrile based copolymer obtained by using the acrylonitrile solution are provided.The acrylonitrile solution of maleimide is such that, when it is subjected to a forced coloration test, the differences .DELTA.L, .DELTA.a, and .DELTA.b values (invariably as absolute values) each between L, a, and b values before and after the test are respectively not more than 5, not more than 5, and not more than 10. The acrylonitrile solution of maleimide is prepared by lowering the water content in the acrylonitrile solution to a level of not more than 0.1% by weight, or causing the acrylonitrile solution to permit coexistence therein of at least one member selected from the group consisting of alkyl-substituted hydroxybenzenes and hindered phenols and at least one member selected from the group consisting of phosphorous esters, phosphoric esters, phosphine, and phosphoric acid amides, or lowering the water content in the acrylonitrile solution to a level of not more than 0.3% by weight and causing the acrylonitrile solution to permit coexistence therein of at least one member selected from the group consisting of alkyl-substituted hydroxybenzenes, hindered phenols, phosphorous esters, phosphoric esters, phosphine, and phosphoric acid amides.
    • 提供了具有透明性的马来酰亚胺的丙烯腈溶液,在处理过程中排除了着色和不透明性,并且稳定性优异,制备丙烯腈溶液的方法以及使用丙烯腈溶液得到的丙烯腈共聚物。 马来酰亚胺的丙烯腈溶液使得当其经受强制着色试验时,差异值DELTA L,DELTA a和DELTA b值(总是作为绝对值)各自在L,a和b值之前和之后 试验分别不大于5,不超过5,不超过10.马来酰亚胺的丙烯腈溶液是通过将丙烯腈溶液中的水含量降低至不超过0.1重量%,或使 丙烯腈溶液,以允许其中选自烷基取代的羟基苯和受阻酚中的至少一种和选自由磷酯,磷酸酯,膦和磷酸酰胺组成的组中的至少一种,或降​​低 丙烯腈溶液中的水含量不超过0.3重量%,并使丙烯腈溶液允许其中共存至少一个成员选择 由烷基取代的羟基苯,受阻酚,亚磷酸酯,磷酸酯,膦和磷酸酰胺组成的组。
    • 8. 发明授权
    • Stabilization method of vinyl compound with hydroxy group and
composition containing such vinyl compound
    • 具有羟基的乙烯基化合物的稳定化方法和含有这种乙烯基化合物的组合物
    • US5760278A
    • 1998-06-02
    • US711206
    • 1996-09-09
    • Koichi NakagawaMitsuaki MakinoYuichi Kita
    • Koichi NakagawaMitsuaki MakinoYuichi Kita
    • C07C67/62C07C253/32C07C255/15C07C69/73
    • C07C255/15C07C253/32C07C67/62
    • A stabilization method of a vinyl compound with hydroxy group of an improved stability is achieved by preventing it from being denatured on storage, transportation, manufacturing process while maintaining its reactivity. A composition containing the vinyl compound with hydroxy group of an improved stability is obtained by the described stabilization method. The stabilization method is characterized by coexisting a vinyl compound with hydroxy group of formula (1), a primary antioxidant, alcohol and/or water, ##STR1## wherein R is a hydrogen atom or an organic residue, X is a --CN group, a --COR.sub.0 group or a --COOR.sub.0 group, and R.sub.0 is a hydrogen atom or an organic residue. In this stabilization method, not less than 50 ppm of alcohol and/or water is added with respect to the vinyl compound with hydroxy group. The stabilization method may be achieved by coexisting the above-defined vinyl compound with hydroxy group, the primary antioxidant and organic acid. In this case, not less than 10 ppm of organic acid is added to the vinyl compound with hydroxy group.
    • 通过防止在保存其反应性的同时在储存,运输,制造过程中变性而实现具有改善的稳定性的具有羟基的乙烯基化合物的稳定方法。 通过所述的稳定化方法可获得含有具有改进的稳定性的羟基的乙烯基化合物的组合物。 稳定化方法的特征在于将乙烯基化合物与式(1)的羟基,主要抗氧化剂,醇和/或水共存,其中R是氢原子或有机残基,X是 - CN基团,-COR0基团或-COOR0基团,R0为氢原子或有机残基。 在该稳定化方法中,相对于具有羟基的乙烯基化合物,不少于50ppm的醇和/或水被添加。 稳定化方法可以通过将上述定义的乙烯基化合物与羟基,主要抗氧化剂和有机酸共存来实现。 在这种情况下,向具有羟基的乙烯基化合物中加入不少于10ppm的有机酸。
    • 10. 发明授权
    • Method for producing scyllo-inositol
    • 鲨肌醇的制备方法
    • US07745671B2
    • 2010-06-29
    • US10576030
    • 2004-10-14
    • Masanori YamaguchiYuichi KitaTetsuya MoriKenji KanbeAkihiro TomodaAtsushi TakahashiWakako Ichikawa
    • Masanori YamaguchiYuichi KitaTetsuya MoriKenji KanbeAkihiro TomodaAtsushi TakahashiWakako Ichikawa
    • C07C35/16C07H1/06C07C35/46
    • C12P7/02C07C29/145C12N9/0004C12N9/0006C12P7/18C12P7/26
    • It is intended to provide a novel NAD+-independent myo-inositol 2-dehydrogenase which converts myo-inositol into scyllo-inosose in the absence of NAD+; a novel enzyme scyllo-inositol dehydrogenase which stereospecifically reduces scyllo-inosose into scyllo-inositol in the presence of NADH or NADPH; and a novel microorganism which belongs to the genus Acetobacter or Burkholderia and can convert myo-inositol into scyllo-inositol. By using these enzymes or the microorganism, scyllo-inositol is produced. Furthermore, scyllo-inositol is purified by adding boric acid and a metal salt to a liquid mixture containing scyllo-inositol and a neutral saccharide other than scyllo-inositol to form a scyllo-inositol/boric acid complex, separating the complex from the liquid mixture, dissolving the thus separated complex in an acid to give an acidic solution or an acidic suspension and then purifying scyllo-inositol from the acidic solution or the acidic suspension.
    • 旨在提供一种新的NAD +独立肌醇2-脱氢酶,其在不存在NAD +的情况下将肌醇转化为鲨肌内糖; 在NADH或NADPH的存在下,立体选择性地将鲨肌内糖降解成鲨肌醇的新型鲨肌醇肌醇脱氢酶; 和属于醋杆菌属或伯克霍尔德氏菌属的新型微生物,可将肌醇转化为鲨肌醇。 通过使用这些酶或微生物,产生鲨肌醇。 此外,通过向含有鲨肌醇和除了鲨肌醇之外的中性糖的液体混合物中加入硼酸和金属盐以形成鲨肌醇/硼酸络合物,将所述络合物与液体混合物分离,将鲨肌醇纯化 将如此分离的络合物溶解在酸中,得到酸性溶液或酸性悬浮液,然后从酸性溶液或酸性悬浮液中纯化鲨肌醇。