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1. 发明申请

US20140228615A1 PARTICLE BEAM IRRADIATION APPARATUS AND PARTICLE BEAM THERAPY SYSTEM 有权
标题翻译：颗粒光束辐射装置和颗粒束治疗系统
公开(公告)号：US20140228615A1
公开(公告)日：2014-08-14
申请号：US14240650
申请日：2011-11-03
申请人： Masahiro Ikeda , Hisashi Harada , Kazushi Hanakawa , Toshihiro Otani , Tadashi Katayose , Taizo Honda , Yukiko Yamada , Yuehu Pu
发明人： Masahiro Ikeda , Hisashi Harada , Kazushi Hanakawa , Toshihiro Otani , Tadashi Katayose , Taizo Honda , Yukiko Yamada , Yuehu Pu
IPC分类号： A61N5/10
CPC分类号： A61N5/1081 , A61N5/1077 , A61N2005/1087 , A61N2005/1095
摘要： A particle beam irradiation apparatus according to the present invention is provided with a vacuum duct that forms a vacuum region through which the charged particle beam passes, a vacuum window through which the charged particle beam is launched from the vacuum region, a scanning electromagnet that scans the charged particle beam; a monitoring apparatus including a position monitor that detects the passing position of a charged particle beam and the beam size thereof, a low-scattering gas filling chamber including the monitoring apparatus, and an irradiation management apparatus that controls irradiation of the charged particle beam; the particle beam irradiation apparatus is characterized in that the low-scattering gas filling chamber is changeably disposed in such a manner that the beam-axis-direction positional relationship between the monitoring apparatus and the vacuum window is a desired one and in that the low-scattering gas filling chamber is filled with a low-scattering gas.
摘要翻译：根据本发明的粒子束照射装置设置有真空管道，该真空管道形成带电粒子束通过的真空区域，从真空区域发射带电粒子束的真空窗口，扫描的扫描电磁体带电粒子束; 监视装置，其包括检测带电粒子束的通过位置的位置监视器及其光束尺寸，包括监视装置的低散射气体填充室以及控制带电粒子束的照射的照射管理装置; 所述粒子束照射装置的特征在于，所述低散射气体充填室可变地设置成使得所述监视装置和所述真空窗口之间的射束轴向位置关系是期望的，散射气体填充室填充有低散射气体。

2. 发明申请

US20140187847A1 PARTICLE BEAM THERAPY SYSTEM 有权
标题翻译：颗粒束治疗系统
公开(公告)号：US20140187847A1
公开(公告)日：2014-07-03
申请号：US14240197
申请日：2011-11-02
申请人： Masahiro Ikeda , Hisashi Harada , Kazushi Hanakawa , Toshihiro Otani , Tadashi Katayose , Taizo Honda , Yukiko Yamada , Yuehu Pu
发明人： Masahiro Ikeda , Hisashi Harada , Kazushi Hanakawa , Toshihiro Otani , Tadashi Katayose , Taizo Honda , Yukiko Yamada , Yuehu Pu
IPC分类号： A61N5/10
CPC分类号： A61N5/1077 , A61N5/1049 , A61N5/1069 , A61N2005/1087
摘要： A particle beam therapy system comprising a treatment table, a treatment table control unit and an irradiation control unit configured to output an instruction for controlling the treatment table control unit, an accelerator and a scanning electromagnet, wherein after the treatment table control unit controls the treatment table so as for a patient isocenter which is reference position of an affected area of a patient to move to a position of an irradiation isocenter which is set at a position which is closer to an irradiation nozzle than an equipment isocenter which is reference of positional relation of the irradiation nozzle and the treatment table, the irradiation control unit outputs an instruction for irradiating the patient with a particle beam.
摘要翻译：一种粒子束治疗系统，包括治疗台，治疗台控制单元和照射控制单元，其被配置为输出用于控制治疗台控制单元的指令，加速器和扫描电磁体，其中在治疗台控制单元控制治疗将患者的中心位置作为患者的受影响区域的基准位置移动到被设定在比作为位置关系的参照的设备等角点更靠近照射喷嘴的位置的照射等角点的位置的照射喷嘴和处理台，照射控制单元输出用于对粒子束照射患者的指示。

3. 发明授权

US08421031B2 Particle beam therapy system 有权
标题翻译：粒子束治疗系统
公开(公告)号：US08421031B2
公开(公告)日：2013-04-16
申请号：US13258772
申请日：2011-03-10
申请人： Taizo Honda , Masahiro Ikeda , Yuehu Pu , Kazushi Hanakawa
发明人： Taizo Honda , Masahiro Ikeda , Yuehu Pu , Kazushi Hanakawa
IPC分类号： H01J3/26 , A61N5/10
CPC分类号： A61N5/1043 , A61N5/1048 , A61N5/1077 , A61N2005/1074 , A61N2005/1087
摘要： The objective is to obtain a particle beam therapy system that can suppress the effect of a leakage dose. There are provided a scanning nozzle that irradiates in a predetermined direction a particle beam emitted from an accelerator; an irradiation control unit that controls operation of the irradiation nozzle in such a way that the particle beam of a predetermined dose is sequentially irradiated onto each of a plurality of spots set in a planar direction in an irradiation subject; and a control unit that on/off-controls emission of the particle beam from the accelerator. The irradiation control unit makes the irradiation nozzle scan in a diluting manner the particle beam onto a predetermined area in the irradiation subject, in a predetermined period after a time point when emission is switched from ON to OFF, or in a period from the time point when emission is switched from ON to OFF to a time point when the particle beam is cut off.
摘要翻译：目的是获得能够抑制泄漏剂量影响的粒子束治疗系统。提供了沿预定方向照射从加速器发射的粒子束的扫描喷嘴; 照射控制单元，其以照射对象的平面方向上设置的多个点顺序地照射预定剂量的粒子束的方式控制照射喷嘴的动作; 以及控制单元，其控制来自加速器的粒子束的发射。照射控制单元使得照射喷嘴在发射从ON切换到OFF之后的预定时间内或在从时间点开始的时间段内，将粒子束以稀释的方式扫描到照射对象的预定区域上当发射从ON切换到截止到粒子束的时间点时。

4. 发明授权

US08933420B2 Particle beam therapy system 有权
标题翻译：粒子束治疗系统
公开(公告)号：US08933420B2
公开(公告)日：2015-01-13
申请号：US14240197
申请日：2011-11-02
申请人： Masahiro Ikeda , Hisashi Harada , Kazushi Hanakawa , Toshihiro Otani , Tadashi Katayose , Taizo Honda , Yukiko Yamada , Yuehu Pu
发明人： Masahiro Ikeda , Hisashi Harada , Kazushi Hanakawa , Toshihiro Otani , Tadashi Katayose , Taizo Honda , Yukiko Yamada , Yuehu Pu
IPC分类号： A61N5/10
CPC分类号： A61N5/1077 , A61N5/1049 , A61N5/1069 , A61N2005/1087
摘要： A particle beam therapy system comprising a treatment table, a treatment table control unit and an irradiation control unit configured to output an instruction for controlling the treatment table control unit, an accelerator and a scanning electromagnet, wherein after the treatment table control unit controls the treatment table so as for a patient isocenter which is reference position of an affected area of a patient to move to a position of an irradiation isocenter which is set at a position which is closer to an irradiation nozzle than an equipment isocenter which is reference of positional relation of the irradiation nozzle and the treatment table, the irradiation control unit outputs an instruction for irradiating the patient with a particle beam.
摘要翻译：一种粒子束治疗系统，包括治疗台，治疗台控制单元和照射控制单元，其被配置为输出用于控制治疗台控制单元的指令，加速器和扫描电磁体，其中在治疗台控制单元控制治疗将患者的中心位置作为患者的受影响区域的基准位置移动到被设定在比作为位置关系的参照的设备等角点更靠近照射喷嘴的位置的照射等角点的位置的照射喷嘴和处理台，照射控制单元输出用于对粒子束照射患者的指示。

5. 发明申请

US20120228521A1 PARTICLE BEAM THERAPY SYSTEM 有权
标题翻译：颗粒束治疗系统
公开(公告)号：US20120228521A1
公开(公告)日：2012-09-13
申请号：US13258772
申请日：2011-03-10
申请人： Taizo Honda , Masahiro Ikeda , Yuehu Pu , Kazushi Hanakawa
发明人： Taizo Honda , Masahiro Ikeda , Yuehu Pu , Kazushi Hanakawa
IPC分类号： A61N5/00
CPC分类号： A61N5/1043 , A61N5/1048 , A61N5/1077 , A61N2005/1074 , A61N2005/1087
摘要： The objective is to obtain a particle beam therapy system that can suppress the effect of a leakage dose. There are provided a scanning nozzle that irradiates in a predetermined direction a particle beam emitted from an accelerator; an irradiation control unit that controls operation of the irradiation nozzle in such a way that the particle beam of a predetermined dose is sequentially irradiated onto each of a plurality of spots set in a planar direction in an irradiation subject; and a control unit that on/off-controls emission of the particle beam from the accelerator. The irradiation control unit makes the irradiation nozzle scan in a diluting manner the particle beam onto a predetermined area in the irradiation subject, in a predetermined period after a time point when emission is switched from ON to OFF, or in a period from the time point when emission is switched from ON to OFF to a time point when the particle beam is cut off.
摘要翻译：目的是获得能够抑制泄漏剂量影响的粒子束治疗系统。提供了沿预定方向照射从加速器发射的粒子束的扫描喷嘴; 照射控制单元，其以照射对象的平面方向上设置的多个点顺序地照射预定剂量的粒子束的方式控制照射喷嘴的动作; 以及控制单元，其控制来自加速器的粒子束的发射。照射控制单元使得照射喷嘴在发射从ON切换到OFF之后的预定时间内或在从时间点开始的时间段内，将粒子束以稀释的方式扫描到照射对象的预定区域上当发射从ON切换到截止到粒子束的时间点时。

6. 发明授权

US09101763B2 Particle beam irradiation apparatus having adjustable low-scattering filling chamber and particle beam therapy system 有权
标题翻译：具有可调低散射填充室和粒子束治疗系统的粒子束照射装置
公开(公告)号：US09101763B2
公开(公告)日：2015-08-11
申请号：US14240650
申请日：2011-11-03
申请人： Masahiro Ikeda , Hisashi Harada , Kazushi Hanakawa , Toshihiro Otani , Tadashi Katayose , Taizo Honda , Yukiko Yamada , Yuehu Pu
发明人： Masahiro Ikeda , Hisashi Harada , Kazushi Hanakawa , Toshihiro Otani , Tadashi Katayose , Taizo Honda , Yukiko Yamada , Yuehu Pu
IPC分类号： A61N5/00 , A61N5/10
CPC分类号： A61N5/1081 , A61N5/1077 , A61N2005/1087 , A61N2005/1095
摘要： A particle beam irradiation apparatus according to the present invention is provided with a vacuum duct that forms a vacuum region through which the charged particle beam passes, a vacuum window through which the charged particle beam is launched from the vacuum region, a scanning electromagnet that scans the charged particle beam; a monitoring apparatus including a position monitor that detects the passing position of a charged particle beam and the beam size thereof, a low-scattering gas filling chamber including the monitoring apparatus, and an irradiation management apparatus that controls irradiation of the charged particle beam; the particle beam irradiation apparatus is characterized in that the low-scattering gas filling chamber is changeably disposed in such a manner that the beam-axis-direction positional relationship between the monitoring apparatus and the vacuum window is a desired one and in that the low-scattering gas filling chamber is filled with a low-scattering gas.
摘要翻译：根据本发明的粒子束照射装置设置有真空管道，该真空管道形成带电粒子束通过的真空区域，从真空区域发射带电粒子束的真空窗口，扫描的扫描电磁体带电粒子束; 监视装置，其包括检测带电粒子束的通过位置的位置监视器及其光束尺寸，包括监视装置的低散射气体填充室以及控制带电粒子束的照射的照射管理装置; 所述粒子束照射装置的特征在于，所述低散射气体充填室可变地设置成使得所述监视装置和所述真空窗口之间的射束轴向位置关系是期望的，散射气体填充室填充有低散射气体。

7. 发明授权

US09079026B2 Particle beam scanning irradiation system 有权
标题翻译：粒子束扫描照射系统
公开(公告)号：US09079026B2
公开(公告)日：2015-07-14
申请号：US14386626
申请日：2012-03-21
申请人： Yuehu Pu , Masahiro Ikeda , Taizo Honda
发明人： Yuehu Pu , Masahiro Ikeda , Taizo Honda
IPC分类号： A61N5/10
CPC分类号： A61N5/1071 , A61N5/103 , A61N5/1031 , A61N5/1043 , A61N2005/1087
摘要： A particle beam scanning irradiation method includes the steps of calculating a planned irradiating particle count of a particle beam for each of irradiation spots, on the basis of a relative amount of particle beam irradiation and a prescription particle-beam dose determined from a particle-beam therapy plan; simulating an irradiation process of the particle beam at each irradiation spot, on the basis of the planned irradiating particle count and a beam current waveform of the particle beam, and calculating a particle count of the particle beam irradiating the diseased portion during a scan shift of the particle beam; correcting the planned irradiating particle count for each irradiation spot by using the irradiating particle count during the scan shift; converting the corrected planned-irradiation particle count into a count value used in a dose monitor; and irradiating the irradiation spot with the particle beam, on the basis of the converted count value.
摘要翻译：粒子束扫描照射方法包括以下步骤：基于粒子束照射的相对量和从粒子束确定的处方粒子束剂量来计算每个照射点的粒子束的计划照射粒子数治疗方案; 基于所计划的照射粒子数和粒子束的束电流波形，模拟在各照射点处的粒子束的照射过程，计算在扫描位移期间照射患病部位的粒子束的粒子数粒子束; 通过使用扫描偏移期间的照射粒子数来校正每个照射点的计划照射粒子数; 将校正的计划照射粒子数转换为剂量监视器中使用的计数值; 并且基于转换后的计数值，用粒子束照射照射点。

8. 发明授权

US08586942B2 Beam position monitor and particle beam therapy system 有权
标题翻译：梁位置监视器和粒子束治疗系统
公开(公告)号：US08586942B2
公开(公告)日：2013-11-19
申请号：US13639998
申请日：2012-01-20
申请人： Taizo Honda , Hisashi Harada , Yuehu Pu , Masahiro Ikeda , Kazushi Hanakawa , Toshihiro Otani , Tadashi Katayose , Yukiko Yamada
发明人： Taizo Honda , Hisashi Harada , Yuehu Pu , Masahiro Ikeda , Kazushi Hanakawa , Toshihiro Otani , Tadashi Katayose , Yukiko Yamada
IPC分类号： H01J3/10
CPC分类号： A61N5/1048 , A61N5/1043 , A61N5/1071 , A61N2005/1074 , A61N2005/1087 , G01T1/29 , G21K5/00 , G21K5/02
摘要： A charged particle beam position monitor is provided with a plurality of position monitors and a beam data processing device that performs calculation processing of the state of a charged particle beam, based on a plurality of signals outputted from the position monitors. The beam data processing device includes a plurality of channel data conversion units that perform AD conversion processing of the plurality of signals outputted from the position monitors; a position size processing unit, for each of the position monitors, that calculates the beam position of the beam, based on voltage information obtained through the AD conversion processing; and an integrated control unit that controls the plurality of channel data conversion units in such a way that while the beam is irradiated onto an irradiation subject, AD conversion processing of the signals is performed at different timings for the respective position monitors.
摘要翻译：带电粒子束位置监视器具有多个位置监视器和根据从位置监视器输出的多个信号执行带电粒子束的状态的计算处理的波束数据处理装置。所述波束数据处理装置包括对从所述位置监视器输出的所述多个信号进行AD转换处理的多个信道数据变换部; 基于通过AD转换处理获得的电压信息，对位置监视器中的每一个计算光束位置的位置尺寸处理单元; 以及集成控制单元，其以这样的方式控制多个通道数据转换单元，即当将光束照射到照射对象时，对于各个位置监视器，在不同的定时执行信号的AD转换处理。

9. 发明申请

US20130190548A1 BEAM POSITION MONITOR AND PARTICLE BEAM THERAPY SYSTEM 有权
标题翻译：光束位置监测器和粒子束治疗系统
公开(公告)号：US20130190548A1
公开(公告)日：2013-07-25
申请号：US13639998
申请日：2012-01-20
申请人： Taizo Honda , Hisashi Harada , Yuehu Pu , Masahiro Ikeda , Kazushi Hanakawa , Toshihiro Otani , Tadashi Katayose , Yukiko Yamada
发明人： Taizo Honda , Hisashi Harada , Yuehu Pu , Masahiro Ikeda , Kazushi Hanakawa , Toshihiro Otani , Tadashi Katayose , Yukiko Yamada
IPC分类号： A61N5/10 , G21K5/00
CPC分类号： A61N5/1048 , A61N5/1043 , A61N5/1071 , A61N2005/1074 , A61N2005/1087 , G01T1/29 , G21K5/00 , G21K5/02
摘要： A charged particle beam position monitor is provided with a plurality of position monitors and a beam data processing device that performs calculation processing of the state of a charged particle beam, based on a plurality of signals outputted from the position monitors. The beam data processing device includes a plurality of channel data conversion units that perform AD conversion processing of the plurality of signals outputted from the position monitors; a position size processing unit, for each of the position monitors, that calculates the beam position of the beam, based on voltage information obtained through the AD conversion processing; and an integrated control unit that controls the plurality of channel data conversion units in such a way that while the beam is irradiated onto an irradiation subject, AD conversion processing of the signals is performed at different timings for the respective position monitors.
摘要翻译：带电粒子束位置监视器具有多个位置监视器和根据从位置监视器输出的多个信号执行带电粒子束的状态的计算处理的波束数据处理装置。所述波束数据处理装置包括对从所述位置监视器输出的所述多个信号进行AD转换处理的多个信道数据变换部; 基于通过AD转换处理获得的电压信息，对位置监视器中的每一个计算光束位置的位置尺寸处理单元; 以及集成控制单元，其以这样的方式控制多个通道数据转换单元，即当将光束照射到照射对象时，对于各个位置监视器，在不同的定时执行信号的AD转换处理。

10. 发明授权

US09327140B2 Beam data processing apparatus and particle beam therapy system 有权
标题翻译：光束数据处理装置和粒子束治疗系统
公开(公告)号：US09327140B2
公开(公告)日：2016-05-03
申请号：US14115028
申请日：2011-08-23
申请人： Taizo Honda , Yuichi Yamamoto , Yuehu Pu
发明人： Taizo Honda , Yuichi Yamamoto , Yuehu Pu
IPC分类号： G01K1/08 , A61N5/10 , G21K5/04
CPC分类号： A61N5/1048 , A61N5/1043 , A61N5/1075 , A61N5/1077 , A61N2005/1074 , A61N2005/1087 , G21K5/04
摘要： A beam data processing apparatus has a plurality of channel data conversion units that convert a plurality of analogue signals outputted from a position monitor into digital signals, a position size processing unit that calculates a beam position, based on voltage information items obtained through processing by the plurality of channel data conversion units, an abnormality determination processing unit that determines the beam position and generates a position abnormality signal, and an integrated control unit that controls the plurality of channel data conversion units in such a way that while a beam is stopped at an irradiation spot, digital signal conversion processing is implemented two or more times; the channel data conversion unit has a plurality of A/D converters, a demultiplexer that distributes analogue signals, and a multiplexer that switches respective digital signals processed by the A/D converters so as to output them to the position size processing unit.
摘要翻译：波束数据处理装置具有多个通道数据转换单元，其将从位置监视器输出的多个模拟信号转换为数字信号，位置大小处理单元，基于通过处理所获得的电压信息项，计算波束位置多个通道数据转换单元，确定光束位置并产生位置异常信号的异常判定处理单元，以及控制多个通道数据转换单元的集成控制单元，使得当光束停止在照射点，数字信号转换处理两次以上; 信道数据转换单元具有多个A / D转换器，分配模拟信号的多路分解器和切换由A / D转换器处理的各个数字信号的多路复用器，以便将它们输出到位置大小处理单元。

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