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1. 发明授权

US4870172A Bisucaberin 失效
公开(公告)号：US4870172A
公开(公告)日：1989-09-26
申请号：US74369
申请日：1987-07-16
申请人： Yoshiro Okami , Shogo Kurasawa , Toshiyuki Kamayama , Atsushi Takahashi , Masaaki Ishizuka , Hamao Umezawa, deceased
发明人： Yoshiro Okami , Shogo Kurasawa , Toshiyuki Kamayama , Atsushi Takahashi , Masaaki Ishizuka , Hamao Umezawa, deceased
IPC分类号： A61K31/395 , A61P35/00 , C07D257/02 , C12P17/10 , C12R1/01
CPC分类号： C12R1/01 , C07D257/02 , C12P17/10
摘要： A novel compound having anti-tumor activity is disclosed which is 1,12-dihydroxy-1,6,12,17-tetraazacyclodocosan-2,5,13,16-tetrone produced microbiologically by culturing a microorganism belonging to the genus of Alteromonas or, in particular, Alteromonas haloplanktis SB-1123. The characterization data of the compound and the microbiological properties of the microorganism are described. The results of in vitro assays are given for the anti-tumor activity of the compound against L-1210 and IMC carcinoma cells.

2. 发明授权

US09610367B2 Particle and contrast agent having the particle 有权
公开(公告)号：US09610367B2
公开(公告)日：2017-04-04
申请号：US13817711
申请日：2011-08-23
申请人： Shinzaburo Ito , Masato Minami , Tatsuki Fukui , Kouichi Kato , Fumio Yamauchi , Yoshinori Tomida , Satoshi Yuasa , Tetsuya Yano , Satoshi Ogawa , Kengo Kanazaki , Atsushi Takahashi , Daisuke Sasaguri , Hiroyuki Aoki
发明人： Shinzaburo Ito , Masato Minami , Tatsuki Fukui , Kouichi Kato , Fumio Yamauchi , Yoshinori Tomida , Satoshi Yuasa , Tetsuya Yano , Satoshi Ogawa , Kengo Kanazaki , Atsushi Takahashi , Daisuke Sasaguri , Hiroyuki Aoki
IPC分类号： A61K9/00 , A61K49/00 , A61K9/51 , A61K49/22 , B82Y15/00 , B82Y30/00
CPC分类号： A61K49/0093 , A61K9/5153 , A61K49/0034 , A61K49/0052 , A61K49/225 , B82Y15/00 , B82Y30/00
摘要： There is provided an ICG-loaded polymer nanoparticle that is dynamically stable, prevents the leakage of contained ICG and the resulting discoloration, and has a high molar absorbance coefficient. The particle contains a hydrophilic dye having a sulfonate group and a hydrophobic polymer, and the particle further contains at least one of a lipid having a positively charged region, a nicotinic acid derivative and a thiamine derivative.

3. 发明授权

US09515277B2 Organic electroluminescent element, organic EL display device and organic EL illumination 有权
标题翻译：有机电致发光元件，有机EL显示装置和有机EL照明
公开(公告)号：US09515277B2
公开(公告)日：2016-12-06
申请号：US12935416
申请日：2009-08-12
申请人： Kazuki Okabe , Atsushi Takahashi , Tomohiro Abe , Yasuyuki Tsurutani , Hideki Sato
发明人： Kazuki Okabe , Atsushi Takahashi , Tomohiro Abe , Yasuyuki Tsurutani , Hideki Sato
IPC分类号： H01L51/50 , C08G61/12 , C08G73/02 , C08L65/00 , C08L79/02 , C09K11/06 , H05B33/14 , H01L51/00
CPC分类号： H01L51/5012 , C08G61/12 , C08G73/026 , C08G2261/135 , C08G2261/141 , C08G2261/1424 , C08G2261/3162 , C08L65/00 , C08L79/02 , C09K11/06 , C09K2211/1433 , H01L51/0035 , H01L51/0043 , H01L51/0058 , H01L51/006 , H01L51/0067 , H01L51/008 , H01L51/0081 , H01L51/5048 , H05B33/14
摘要： To provide an organic electroluminescent element having a low driving voltage, high current efficiency and high voltage efficiency.An organic electroluminescent element comprising an anode, a cathode and an organic layer disposed between the anode and the cathode, wherein the organic layer comprises a mixed layer containing a light-emitting low molecular compound and/or a charge-transporting low molecular compound in a film containing an insolubilized polymer obtained by insolubilizing an insolubilizing polymer, and, adjacent to the mixed layer, a layer containing a light-emitting low molecular compound and a charge-transporting low molecular compound and not containing an insolubilized polymer.
摘要翻译：一种有机电致发光元件，包括阳极，阴极和设置在阳极和阴极之间的有机层，其中有机层包括含有发光低分子化合物和/或电荷输送低分子化合物的混合层，含有通过使不溶性聚合物不溶化而得到的不溶性聚合物和与混合层相邻的含有发光低分子化合物和电荷输送性低分子化合物并且不含不溶性聚合物的层的膜。

4. 发明授权

US09009519B2 Timing control device and control method thereof 有权
标题翻译：定时控制装置及其控制方法
公开(公告)号：US09009519B2
公开(公告)日：2015-04-14
申请号：US13569378
申请日：2012-08-08
申请人： Atsushi Takahashi
发明人： Atsushi Takahashi
IPC分类号： G06F1/14 , F02D41/28 , F02D41/24
CPC分类号： H03K3/017 , F02D41/2403 , F02D41/28 , F02D2250/14 , G06F1/14
摘要： Provided is a timing control device including: a storage unit that stores multiple pieces of timing control information including identification information and expected value data; a first selector that selectively outputs any of the multiple pieces of timing control information; a second selector that selectively outputs any of data items output from data output devices based on the identification information; a reference data generation unit that generates reference data based on expected value data and a data item output from the second selector in synchronization with a switching of the timing control information; a comparator that compares the reference data with the data item output from the second selector and outputs a coincidence signal when the reference data and the data item coincide with each other; and an output control unit that outputs a timing signal according to the coincidence signal.
摘要翻译：提供了一种定时控制装置，包括：存储单元，存储包括识别信息和期望值数据的多个定时控制信息; 第一选择器，其选择性地输出所述多个定时控制信息中的任何一个; 第二选择器，其基于所述识别信息选择性地输出从数据输出设备输出的任何数据项; 参考数据生成单元，其与定时控制信息的切换同步地基于期望值数据和从第二选择器输出的数据项生成参考数据; 比较器，当参考数据和数据项彼此一致时，比较参考数据和从第二选择器输出的数据项，并输出一致信号; 以及输出控制单元，其根据所述一致信号输出定时信号。

5. 发明授权

US08912145B2 Vaccine composition for prophylaxis and/or therapy of Alzheimer's disease 有权
标题翻译：用于预防和/或治疗阿尔茨海默病的疫苗组合物
公开(公告)号：US08912145B2
公开(公告)日：2014-12-16
申请号：US13290960
申请日：2011-11-07
申请人： Teruhiko Terakawa , Hisakazu Hasegawa , Yasushi Shimada , Atsushi Takahashi , Takeshi Kawarabayashi , Mikio Shoji
发明人： Teruhiko Terakawa , Hisakazu Hasegawa , Yasushi Shimada , Atsushi Takahashi , Takeshi Kawarabayashi , Mikio Shoji
IPC分类号： C12N15/62 , C12N15/82 , A61P25/28 , A61K38/00 , A61K38/08 , A61K36/48 , C07K7/06 , C12N15/12 , C12N15/29 , A61K39/00 , C07K14/415 , C07K14/47
CPC分类号： A61K39/0007 , A61K2039/55516 , A61K2039/6031 , C07K14/415 , C07K14/4711 , C12N15/62 , C12N15/8257 , C12N15/8258
摘要： A vaccine composition for prophylaxis and/or therapy of Alzheimer's disease, which comprises a fusion protein prepared by inserting a single or tandemly repeated multiple copies of amyloid β antigenic peptide having 5 to 15 continuous amino acid residues derived from the N-terminus of amyloid β peptide into a wild type seed storage protein.
摘要翻译：一种用于预防和/或治疗阿尔茨海默氏病的疫苗组合物，其包含通过插入单个或串联重复的多个淀粉样蛋白复合物制备的融合蛋白; 具有衍生自淀粉样蛋白N末端的5至15个连续氨基酸残基的抗原肽; 肽成野生型种子储存蛋白。

6. 发明授权

US08790349B2 Autologous bone collection device having enhanced suction efficiency 有权
标题翻译：具有提高抽吸效率的自体骨收集装置
公开(公告)号：US08790349B2
公开(公告)日：2014-07-29
申请号：US11908677
申请日：2006-03-14
申请人： Atsushi Takahashi
发明人： Atsushi Takahashi
IPC分类号： A61F5/00 , A61C17/08 , A61C17/06 , A61C1/00 , A61B10/02 , A61M1/00
CPC分类号： A61M1/0056 , A61B10/025 , A61B17/1635 , A61C1/0076 , A61C17/043 , A61M1/008
摘要： A bone piece collector wherein a blade (4) coming into tight contact with the surface of a filter (2) under an appropriate pressure is provided in order to prevent lowering in the efficiency of suction work due to sampled bone chips adhering to the surface of the filter (2) in the bone piece collector provided in a suction line in order to sample a bone, i.e. a transplantation material in autologous bone transplantation, the blade (4) is rotated while being pressed against the surface of the filter (2) with a finger pressure or a motor drive force, and the sampled bone chips are moved in a certain direction so that clogging of the filter (2) is eliminated and the suction efficiency can be recovered at any time.
摘要翻译：提供了一种骨片收集器，其中在适当的压力下与叶片（2）的表面紧密接触的叶片（4），以防止由于采样的骨屑粘附在表面上而引起的吸力效率的降低设置在抽吸线中的骨片收集器中的过滤器（2），以便对骨骼进行采样，即在自体骨移植中的移植材料，叶片（4）在被压靠过滤器（2）的表面的同时旋转，用手指压力或马达驱动力，使取样的骨屑沿一定的方向移动，从而消除了过滤器（2）的堵塞，并且可随时回收吸入效率。

7. 发明授权

US08764003B2 Control method of feeder and image forming system 有权
标题翻译：进料器和成像系统的控制方法
公开(公告)号：US08764003B2
公开(公告)日：2014-07-01
申请号：US13852263
申请日：2013-03-28
申请人： Hiroshi Oyama , Kenji Izumiya , Kiyoto Kojima , Atsushi Takahashi
发明人： Hiroshi Oyama , Kenji Izumiya , Kiyoto Kojima , Atsushi Takahashi
IPC分类号： B65H5/00
CPC分类号： B65H5/062 , B41J13/0018 , B65H3/44 , B65H5/26 , B65H9/006 , B65H2402/10 , B65H2404/13 , B65H2404/14 , B65H2405/15 , B65H2405/332 , B65H2701/1916 , G03G15/6511 , G03G15/6567 , G03G15/6588 , G03G15/6594 , G03G2215/00514
摘要： When conveying an envelope, a posture of the envelope is corrected by hitting a closed portion of the envelope, which is opposite side of an opened portion of the envelope, against a nip portion between upper and lower rollers of the pre-registration rollers and the envelope is then conveyed with the envelope being nipped by the upper and lower rollers of the pre-registration rollers. The upper and lower rollers of the pre-registration rollers nip the envelope to remove air from the envelope. When setting an envelope mode to control a conveying speed of the envelope based on a coverage rate of an image to be formed on the envelope, the conveying speed of the envelope is controlled by adjusting a rotation speed of the registration rollers based on the coverage rate of the set envelope mode.
摘要翻译：当输送信封时，通过将与外壳的打开部分的相反侧的信封的封闭部分击打在预定位辊的上辊和下辊之间的辊隙部分上来纠正信封的姿势，信封随后被预定位辊的上辊和下辊夹持。预定位辊的上下辊压合信封以从信封中除去空气。当设置信封模式以基于要在信封上形成的图像的覆盖率来控制信封的传送速度时，通过基于覆盖率调整对位辊的转速来控制信封的传送速度的设定包络模式。

8. 发明申请

US20130162199A1 RECHARGEABLE ELECTRIC APPARATUS 审中-公开
标题翻译：可充电电器
公开(公告)号：US20130162199A1
公开(公告)日：2013-06-27
申请号：US13820719
申请日：2011-08-10
申请人： Atsushi Takahashi , Yoshinori Katsura
发明人： Atsushi Takahashi , Yoshinori Katsura
IPC分类号： H02J7/00
CPC分类号： H02J7/0052 , H01M10/44 , H02J7/0068
摘要： A rechargeable electric apparatus includes a switching device (12), a first shunt resistor (13-1) that connects the switching device (12) and a positive electrode of a secondary battery (11), a second shunt resistor (13-2) that connects a load (14) and the positive electrode of the secondary battery (11), and a control unit (15). The control unit (15) controls turning on and off of the switching device (12) on the basis of voltages at two ends of the first shunt resistor (13-1) and voltages at two ends of the second shunt resistor (13-2) in order to control a supply current flowing to the secondary battery (11) via the first shunt resistor (13-1) and to control a load current flowing to the load (14) via the second shunt resistor (13-2).
摘要翻译：可再充电电器包括开关装置（12），连接开关装置（12）和二次电池（11）的正电极的第一分流电阻器（13-1），第二分流电阻器（13-2）连接负载（14）和二次电池（11）的正极以及控制单元（15）。控制单元（15）基于第一分流电阻器（13-1）两端的电压和第二分流电阻器（13-2）两端的电压来控制开关装置（12）的导通和截止），以通过第一分流电阻（13-1）控制流向二次电池（11）的电源电流，并且经由第二分流电阻（13-2）控制流向负载（14）的负载电流。

9. 发明申请

US20130134402A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, ORGANIC ELECTROLUMINESCENCE DEVICE, ORGANIC EL DISPLAY DEVICE, AND ORGANIC EL LIGHTING 有权
标题翻译：有机电致发光元件，有机电致发光器件，有机EL显示器件和有机EL照明
公开(公告)号：US20130134402A1
公开(公告)日：2013-05-30
申请号：US13736423
申请日：2013-01-08
申请人： Futoshi Tanaka , Kazuki Okabe , Atsushi Takahashi
发明人： Futoshi Tanaka , Kazuki Okabe , Atsushi Takahashi
IPC分类号： H01L51/52
CPC分类号： H01L51/52 , C09B1/00 , C09B1/005 , C09B47/00 , C09B47/045 , C09B57/00 , C09B57/001 , H01L51/0067 , H01L51/0072 , H01L51/5004 , H01L51/5048
摘要： The present invention relates to an organic electroluminescence element which comprises an anode, a luminescent layer, two or more electron transport layers and a cathode, in this order, wherein at least one of the two or more electron transport layers adjoins the luminescent layer, the luminescent layer contains a luminescent material and a charge transport material, the electron transport layer which adjoins the luminescent layer contains a charge transport material, the charge transport material contained in the luminescent layer and the charge transport material contained in the electron transport layer which adjoins the luminescent layer may be the same material or may be different material, and the specific electron affinities EA1, EA2 and EA3, and the specific work function WF satisfy the specific relationship.
摘要翻译：本发明涉及一种有机电致发光元件，其包括阳极，发光层，两个或更多个电子传输层和阴极，其中两个或更多个电子传输层中的至少一个与发光层相邻，发光层含有发光材料和电荷传输材料，与发光层相邻的电子输送层含有电荷输送材料，发光层中所含的电荷输送材料和电子输送层中所含的电荷输送材料，发光层可以是相同的材料或可以是不同的材料，并且特定的电子亲和力EA1，EA2和EA3以及具体的功函数WF满足具体的关系。

10. 发明授权

US08326110B2 Flexible optical waveguide having a cladding layer composed of a resin for forming a cladding layer and a base material film 有权
标题翻译：具有由用于形成包覆层的树脂构成的包覆层和基材膜的挠性光波导
公开(公告)号：US08326110B2
公开(公告)日：2012-12-04
申请号：US12829164
申请日：2010-07-01
申请人： Tomoaki Shibata , Tatsuya Makino , Masami Ochiai , Atsushi Takahashi , Toshihiko Takasaki
发明人： Tomoaki Shibata , Tatsuya Makino , Masami Ochiai , Atsushi Takahashi , Toshihiko Takasaki
IPC分类号： G02B6/00 , G02B6/12 , G02B6/10
CPC分类号： C08F2/50 , C08L33/062 , C08L33/068 , C08L63/10 , C08L71/12 , G02B6/138 , G03F7/027 , G03F7/032 , C08L2666/02 , C08L2666/22
摘要： Disclosed, among other features, is a flexible optical waveguide, having one resin film for forming a core layer and two resin films for forming a cladding layer. At least one of the resin films for forming the cladding layer is composed of a resin for forming a cladding layer and a base material film, and the base material film is arranged on an outer side of the cladding layer with respect to the core layer.
摘要翻译：公开了一种柔性光波导，其具有用于形成芯层的一个树脂膜和用于形成包覆层的两个树脂膜。用于形成包覆层的树脂膜中的至少一个由用于形成包覆层的树脂和基材膜构成，并且基材膜相对于芯层布置在包覆层的外侧。

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