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1. 发明申请

US20070148759A1 Biological sample discrimination device, biological sample discriminating method, and biological sample discriminating plate 审中-公开
标题翻译：生物样本识别装置，生物样本识别方法和生物样本鉴别板
公开(公告)号：US20070148759A1
公开(公告)日：2007-06-28
申请号：US10584300
申请日：2004-12-27
申请人： Yoshinori Amano , Hideaki Hashimoto , Takeshi Nishida , Kazuyoshi Mori , Ryuuji Shimizu , Hiroshi Andou , Kenji Nakanishi , Naoki Yanagihara , Miho Hayashi
发明人： Yoshinori Amano , Hideaki Hashimoto , Takeshi Nishida , Kazuyoshi Mori , Ryuuji Shimizu , Hiroshi Andou , Kenji Nakanishi , Naoki Yanagihara , Miho Hayashi
IPC分类号： C12M3/00
CPC分类号： B01L3/502715 , B01L3/5025 , B01L2200/027 , B01L2300/0803 , B01L2300/0864 , B01L2300/1844 , B01L2400/0409 , G01N27/447
摘要： There is provided a plate (10) on which a channel pattern (110) is formed, which channel pattern includes a first channel (116) into which a buffer agent is injected, and a second channel (117) having, in a portion thereof, a quantification part (117a) that has a portion common to the first channel and holds a predetermined amount of a biological sample, the biological sample being injected into the channel including the quantification part, and the plate (10) is rotated at a high speed by a filling unit (20) to fill the buffer agent in the first channel, and thereafter, the second channel is pressurized by a discrimination unit (30) to fill the biological sample in the second channel, and simultaneously, a predetermined amount of the biological sample is added into the buffer agent. Therefore, when performing discrimination of the biological sample, a discrimination result can be obtained accurately in a short time without the necessity of complicated preparation works.
摘要翻译：提供了一个板（10），其上形成有通道图案（110），该通道图案包括其中注入有缓冲剂的第一通道（116）和第二通道（117），第二通道，具有与第一通道相同的部分并保持预定量的生物样品的定量部分（117a），将生物样品注入包括量化部分的通道中，并且板（10）以通过填充单元（20）高速填充第一通道中的缓冲剂，此后，第二通道被鉴别单元（30）加压以填充第二通道中的生物样品，同时施加预定量的生物样品加入到缓冲剂中。因此，当进行生物样品的鉴别时，可以在短时间内准确地获得鉴别结果，而不需要复杂的准备工作。

2. 发明申请

US20110256572A1 BIOLOGICAL SAMPLE DISCRIMINATION APPARATUS, BIOLOGICAL SAMPLE DISCRIMINATION METHOD, AND BIOLOGICAL SAMPLE DISCRIMINATION PLATE 审中-公开
标题翻译：生物样本鉴别装置，生物样品鉴别方法和生物样品鉴别板
公开(公告)号：US20110256572A1
公开(公告)日：2011-10-20
申请号：US13044046
申请日：2011-03-09
申请人： Yoshinori AMANO , Hideaki Hashimoto , Takeshi Nishida , Kazuyoshi Mori , Ryuuji Shimizu , Hiroshi Andou , Kenji Nakanishi , Naoki Yanagihara , Miho Hayashi
发明人： Yoshinori AMANO , Hideaki Hashimoto , Takeshi Nishida , Kazuyoshi Mori , Ryuuji Shimizu , Hiroshi Andou , Kenji Nakanishi , Naoki Yanagihara , Miho Hayashi
IPC分类号： C12Q1/02
CPC分类号： B01L3/502715 , B01L3/5025 , B01L2200/027 , B01L2300/0803 , B01L2300/0864 , B01L2300/1844 , B01L2400/0409 , G01N27/447
摘要： A plate on which a channel pattern is formed, which channel pattern includes a first channel into which a buffer agent is injected, and a second channel having, in a portion thereof, a quantification part that has a portion common to the first channel and holds a predetermined amount of a biological sample, the biological sample being injected into the channel including the quantification part, and the plate is rotated at a high speed by a filling unit to fill the buffer agent in the first channel, and thereafter, the second channel is pressurized by a discrimination unit to fill the biological sample in the second channel, and simultaneously, a predetermined amount of the biological sample is added into the buffer agent. Therefore, when performing discrimination of the biological sample, a discrimination result can be obtained accurately in a short time without the necessity of complicated preparation works.
摘要翻译：其上形成有通道图案的板，哪个通道图案包括其中注入有缓冲剂的第一通道，以及第二通道，其在其一部分中具有量化部分，该量化部分具有与第一通道共同的部分预定量的生物样品，将生物样品注入包括定量部分的通道中，并且板通过填充单元高速旋转以填充第一通道中的缓冲剂，然后第二通道由识别单元加压以填充第二通道中的生物样品，同时将预定量的生物样品加入到缓冲剂中。因此，当进行生物样品的鉴别时，可以在短时间内准确地获得鉴别结果，而不需要复杂的准备工作。

3. 发明授权

US6146514A Apparatus and method for measuring acidity 失效
标题翻译：测量酸度的仪器和方法
公开(公告)号：US6146514A
公开(公告)日：2000-11-14
申请号：US20139
申请日：1998-02-06
申请人： Kiyoko Takamura , Fumiyo Kusu , Takeshi Nishida , Hideaki Hashimoto , Hidefumi Yabu , Kazuyoshi Mori , Yuji Hiraishi , Yasuyuki Hanada , Tetsuji Soeda , Tsuyoshi Kusakabe , Tetsuya Nishio
发明人： Kiyoko Takamura , Fumiyo Kusu , Takeshi Nishida , Hideaki Hashimoto , Hidefumi Yabu , Kazuyoshi Mori , Yuji Hiraishi , Yasuyuki Hanada , Tetsuji Soeda , Tsuyoshi Kusakabe , Tetsuya Nishio
IPC分类号： G01N33/03 , G01N27/48 , G01N27/49 , G01N33/14 , G01F1/64 , G01N27/26
CPC分类号： G01N27/3277
摘要： An acidity measuring apparatus includes a measuring container for accommodating an electrolyte solution including one of a 1,2-benzoquinone derivative and a 1,4-benzoquinone derivative, an organic solvent, an electrolyte and an acid-containing subject for measurement; a working electrode, a counter electrode and a reference electrode section provided in the measuring container and immersed in the electrolyte solution; and a control section for sweeping a potential of the working electrode within a prescribed range and for detecting a value of a pre-peak current generated by the acid and flowing between the working electrode and the counter electrode.
摘要翻译：酸度测量装置包括用于容纳包含1,2-苯醌衍生物和1,4-苯醌衍生物之一的电解质溶液的测量容器，有机溶剂，电解质和含酸的受试者; 设置在测量容器中并浸入电解液中的工作电极，对电极和参比电极部分; 以及用于将工作电极的电位扫描在规定范围内并用于检测由酸产生的预峰值电流的值并在工作电极和对电极之间流动的控制部分。

4. 发明授权

US06551493B2 Ultraviolet light measuring chip and ultraviolet light sensor using the same 失效
标题翻译：紫外光测量芯片和紫外线传感器使用相同
公开(公告)号：US06551493B2
公开(公告)日：2003-04-22
申请号：US09820637
申请日：2001-03-30
申请人： Kazuyoshi Mori , Takeshi Nishida , Hideaki Hashimoto
发明人： Kazuyoshi Mori , Takeshi Nishida , Hideaki Hashimoto
IPC分类号： G01N27403
CPC分类号： G01J1/429
摘要： An ultraviolet light measuring chip and a sensor are provided simple in structure, easy to handle and of high precise measurement. The chip comprises a first reaction chamber for detection of total received light and a second reaction chamber for detection of ultraviolet-cut received light. The first and second chambers contain or hold therein counter and reference electrodes immersed in coexistent electrolyte solution containing quinone, organic solvent and electrolyte the solution being also contained the chambers. The first chamber has a total light transmission window and a first working electrode immersed in the electrolyte solution. The second chamber has an ultraviolet-cut light transmission window and a second working electrode immersed in the electrolyte solution. The sensor is adapted to sweep voltages of the first and second working electrodes to the respective reference electrodes, detect respective currents and calculate out an amount of ultraviolet light from difference of the detected currents.
摘要翻译：紫外线测量芯片和传感器的结构简单，易于处理和高精度测量。芯片包括用于检测总接收光的第一反应室和用于检测紫外线切割的接收光的第二反应室。第一和第二腔室包含或保持其中浸没在包含醌，有机溶剂和电解质的共存电解质溶液中的反向和参考电极，该溶液也包含在室中。第一室具有总透光窗和浸在电解液中的第一工作电极。第二室具有紫外线切割透光窗和浸在电解液中的第二工作电极。该传感器适于将第一和第二工作电极的电压扫描到相应的参考电极，检测相应的电流并根据检测到的电流的差异计算出紫外线的量。

5. 发明授权

US08764682B2 Measurement device and puncture device 有权
标题翻译：测量装置和穿刺装置
公开(公告)号：US08764682B2
公开(公告)日：2014-07-01
申请号：US13147255
申请日：2010-02-03
申请人： Kiyohiro Horikawa , Takeshi Nishida , Yoshinori Amano , Tetsuya Takashima , Keisuke Matsumura , Masahiro Kitagawa
发明人： Kiyohiro Horikawa , Takeshi Nishida , Yoshinori Amano , Tetsuya Takashima , Keisuke Matsumura , Masahiro Kitagawa
IPC分类号： A61B5/00
CPC分类号： A61B5/15186 , A61B5/14532 , A61B5/150022 , A61B5/150099 , A61B5/150358 , A61B5/15113 , A61B5/15134 , A61B5/15136 , A61B5/157
摘要： Disclosed are a measurement device and a puncture device that prevent thermal loss and enable decreased cost in laser units. A laser unit (200) of a measurement device (100) is equipped with a lens barrel (210), a laser rod (220) disposed inside the lens barrel (210), a flash lamp (230) which is disposed opposite the laser rod (220) inside the lens barrel (210) and in which an inert gas is sealed inside a hard glass tube (231), and supports (241, 242, 243, 244), which are made from a material with thermal conductivity of 100 W/(mK) or more, at least parts of which are disposed outside of the lens barrel (210), and which support the circumferential surface of the hard glass tube (231) in a housing.
摘要翻译：公开了一种能够防止热损失并且能够降低激光单元成本的测量装置和穿刺装置。测量装置（100）的激光单元（200）配备有透镜镜筒（210），设置在镜筒（210）内部的激光棒（220），与激光器相对设置的闪光灯（230）在玻璃管（210）内的惰性气体被密封在玻璃管（231）内部的支撑件（220），以及由导热性好的材料制成的支撑件（241,242,243,244） 100W /（mK）以上，其至少一部分设置在镜筒210的外侧，并将硬玻璃管231的周面支撑在壳体内。

6. 发明授权

US08556828B2 Blood test device 有权
标题翻译：血液检测装置
公开(公告)号：US08556828B2
公开(公告)日：2013-10-15
申请号：US12278825
申请日：2007-02-09
申请人： Yoshinori Amano , Masaki Fujiwara , Takeshi Nishida
发明人： Yoshinori Amano , Masaki Fujiwara , Takeshi Nishida
IPC分类号： A61B5/00 , A61B17/14 , A61B17/32
CPC分类号： A61B5/157 , A61B5/150022 , A61B5/150099 , A61B5/150175 , A61B5/15019 , A61B5/150213 , A61B5/150358 , A61B5/150412 , A61B5/150519 , A61B5/150916 , A61B5/150954 , A61B5/15113 , A61B5/15117 , A61B5/15123 , A61B5/1513 , A61B5/1519 , A61B5/15194
摘要： A blood test device by which the amount of plumped skin at a puncture site for conducting a blood test or collecting blood can be controlled so that a blood component can be accurately measured. The blood test device includes: a housing; an inner tube provided in one side of the housing; a reciprocating unit which reciprocates within the inner tube; a blood collection needle connected to the reciprocating unit; a blood sensor facing to the blood collection needle and being located at the tip of the inner tube; a measurement circuit to which a signal is fed from the blood sensor; and a negative pressure unit driven by the measurement circuit. An outer tube, that is a tube covering the inner tube, has an opening in the tip side of the inner tube, is capable of moving relative to the inner tube, and is provided so as to return to a definite relative position. The negative pressure provider can apply a negative pressure to the inside of the outer tube.
摘要翻译：可以控制用于进行血液检查或血液收集的穿刺部位的皮肤的皮肤的量的血液检查装置，从而能够精确地测量血液成分。血液检查装置包括：壳体; 设置在所述壳体的一侧中的内管; 在内管内往复运动的往复运动单元; 与往复运动单元连接的采血针; 位于采血针的血液传感器，位于内管的前端; 从血液传感器馈送信号的测量电路; 以及由测量电路驱动的负压单元。外管是覆盖内管的管，在内管的前端具有开口，能够相对于内管移动，并且设置成返回到确定的相对位置。负压供应器可以向外管的内部施加负压。

7. 发明授权

US08414504B2 Blood test device 失效
标题翻译：血液检测装置
公开(公告)号：US08414504B2
公开(公告)日：2013-04-09
申请号：US12293513
申请日：2007-03-22
申请人： Masaki Fujiwara , Yoshinori Amano , Takeshi Nishida , Toshihiro Akiyama , Masataka Nadaoka , Toshiki Matsumoto , Kenichi Hamanaka , Kiyohiro Horikawa , Koji Miyoshi
发明人： Masaki Fujiwara , Yoshinori Amano , Takeshi Nishida , Toshihiro Akiyama , Masataka Nadaoka , Toshiki Matsumoto , Kenichi Hamanaka , Kiyohiro Horikawa , Koji Miyoshi
IPC分类号： A61B5/00 , A61B18/18 , B65D81/00
CPC分类号： A61B5/157 , A61B5/1486 , A61B5/150022 , A61B5/150076 , A61B5/150099 , A61B5/150145 , A61B5/150213 , A61B5/150259 , A61B5/150358 , A61B5/150954 , A61B5/15138
摘要： A blood test device using a laser as a puncture member. More specifically, in a blood test device using a laser as a puncture member, the skin can be fixed at a definite position by raising the punctured skin under negative pressure, and thus the skin is brought into close contact with a blood sensor and the laser is focused on the vicinity of the blood sensor face. Thus, it is possible to provide a blood test device of the laser puncture type in which the skin can be surely punctured while giving little pain to a patient.
摘要翻译：使用激光作为穿刺部件的血液检查装置。更具体地，在使用激光作为穿刺构件的血液检查装置中，通过在负压下升高穿刺皮肤，可以将皮肤固定在确定的位置，从而使皮肤与血液传感器和激光器紧密接触聚焦在血液传感器面附近。因此，可以提供一种激光穿刺型的血液检查装置，其中可以可靠地刺穿皮肤，同时对患者几乎没有疼痛。

8. 发明申请

US20100168615A1 BLOOD TEST DEVICE 有权
标题翻译：血液测试装置
公开(公告)号：US20100168615A1
公开(公告)日：2010-07-01
申请号：US12278825
申请日：2007-02-09
申请人： Yoshinori Amano , Masaki Fujiwara , Takeshi Nishida
发明人： Yoshinori Amano , Masaki Fujiwara , Takeshi Nishida
IPC分类号： A61B5/151
CPC分类号： A61B5/157 , A61B5/150022 , A61B5/150099 , A61B5/150175 , A61B5/15019 , A61B5/150213 , A61B5/150358 , A61B5/150412 , A61B5/150519 , A61B5/150916 , A61B5/150954 , A61B5/15113 , A61B5/15117 , A61B5/15123 , A61B5/1513 , A61B5/1519 , A61B5/15194
摘要： A blood test device by which the amount of plumped skin at a puncture site for conducting a blood test or collecting the blood can be controlled at a constant amount so that a blood component can be accurately measured. Namely, a blood test device comprising: a housing; an inner tube provided in one side of the housing; a reciprocating unit which reciprocates within the inner tube; a blood collection needle connected to the reciprocating unit; a blood sensor facing to the blood collection needle and being located at the tip of the inner tube; a measurement circuit to which a signal is fed from the blood sensor; and a negative pressure unit driven by the measurement circuit; which further has an outer tube that is a tube covering the inner tube, having an opening in the tip side of the inner tube, being capable of relatively moving to the inner tube, and being provided so as to return to a definite relative position. The negative pressure unit as described above can apply a negative pressure to the inside of the outer tube.
摘要翻译：用于血液检查装置，通过该测试装置可以将用于进行血液检查或血液收集的穿刺部位的皮肤的皮肤量控制在一定的量，从而可以精确地测量血液成分。即，一种血液检查装置，包括：壳体; 设置在所述壳体的一侧中的内管; 在内管内往复运动的往复运动单元; 与往复运动单元连接的采血针; 位于采血针的血液传感器，位于内管的前端; 从血液传感器馈送信号的测量电路; 以及由测量电路驱动的负压单元; 其还具有外管，该外管是覆盖内管的，具有在内管的前端侧的开口，能够相对移动到内管，并且设置成返回到确定的相对位置。如上所述的负压单元可以向外管的内部施加负压。

9. 发明申请

US20100191147A1 PIERCING DEVICE AND BLOOD INSPECTION DEVICE 有权
标题翻译：刺激装置和血液检查装置
公开(公告)号：US20100191147A1
公开(公告)日：2010-07-29
申请号：US12670950
申请日：2008-07-31
申请人： Koji Miyoshi , Takeshi Nishida , Yoshinori Amano , Toshiki Matsumoto , Masataka Nadaoka
发明人： Koji Miyoshi , Takeshi Nishida , Yoshinori Amano , Toshiki Matsumoto , Masataka Nadaoka
IPC分类号： A61B5/15 , A61M1/00
CPC分类号： A61B5/1411 , A61B5/14532 , A61B5/14535 , A61B5/1486 , A61B5/150022 , A61B5/150099 , A61B5/150175 , A61B5/150213 , A61B5/150358 , A61B5/150763 , A61B5/150954 , A61B5/15113 , A61B5/15138 , A61B5/157
摘要： A piercing device and a blood inspection device that have increased safety. The piercing device (111) has a piercing button (113) placed on the front surface of a first case (112a), a base (114) being a piecing opening provided projecting from the front surface of the first case (112a), and a laser emission device (115) received in the first case (112a). First safety means (117) prevents emission of a laser beam (115a) to the outside when the first case (112a) and a second case (112b) are superposed on each other. When the base (114) is depressed after the second case (112b) is moved from the superposed state where the second case (112b) is superposed on the first case (112a) to a non-superposed state where the second case (112b) is not, a switch (114b) detects the depression of the base (114) and second safety means (118) to enable depression of the piercing button (113).
摘要翻译：具有增加安全性的穿刺装置和血液检查装置。穿刺装置（111）具有设置在第一壳体（112a）的前表面上的穿刺按钮（113），基部（114）是从第一壳体（112a）的前表面突出设置的接头开口，以及接收在第一壳体（112a）中的激光发射装置（115）。当第一壳体（112a）和第二壳体（112b）彼此叠置时，第一安全装置（117）防止激光束（115a）向外部发射。当第二壳体（112b）从第二壳体（112b）叠置在第一壳体（112a）上的叠置状态移动到第二壳体（112b）的非重叠状态之后，当基座（114）被压下时，不是，开关（114b）检测基座（114）和第二安全装置（118）的按压以能够按压穿刺按钮（113）。

10. 发明授权

US08657762B2 Blood test device 有权
标题翻译：血液检测装置
公开(公告)号：US08657762B2
公开(公告)日：2014-02-25
申请号：US12669254
申请日：2008-07-18
申请人： Tetsuya Takashima , Masaki Fujiwara , Takeshi Nishida , Yoshinori Amano , Toshiki Matsumoto , Kenichi Hamanaka , Keisuke Matsumura , Yohei Hashimoto
发明人： Tetsuya Takashima , Masaki Fujiwara , Takeshi Nishida , Yoshinori Amano , Toshiki Matsumoto , Kenichi Hamanaka , Keisuke Matsumura , Yohei Hashimoto
IPC分类号： A61B5/00
CPC分类号： A61B5/150954 , A61B5/150022 , A61B5/150099 , A61B5/150267 , A61B5/150358 , A61B5/150412 , A61B5/150793 , A61B5/150847 , A61B5/15087 , A61B5/150961 , A61B5/15113 , A61B5/15136 , A61B5/15146 , A61B5/1519 , A61B5/157
摘要： A blood test device (21) ensuring successful measurement wherein fingers scarcely slip out from the blood test device and blood never sticks to other sites in the course from the puncture of the patient's skin to the completion of the blood test. This blood test device (21) comprises a cartridge (24) in which sensors (23) pooling blood oozing out from the punctured skin are stored in a layered state, a transport unit transporting a single sensor sheet (23) from the inside of the cartridge (24) to the outside, a holder (25) holding the transported sensor (23), a laser emitting unit (26) puncturing the skin in the state where the sensor (23) is held by the holder (25), and a pump (28) keeping the inside of the holder (25) and the inside of the cartridge (24) under negative pressure.
摘要翻译：一种确保成功测量的血液检查装置（21），其中手指几乎不从血液检查装置中滑出，并且在从穿刺患者皮肤到完成血液测试的过程中，血液不会粘附到其他部位。该血液检查装置（21）包括：盒（24），其中收集从穿刺皮肤渗出的血液的传感器（23）以分层状态存储;传送单元，其从内部传送单个传感器片（23）盒（24）到外部，保持传送传感器（23）的保持器（25），在传感器（23）被保持器（25）保持的状态下刺穿皮肤的激光发射单元（26）将保持器（25）的内部和药筒（24）的内部保持在负压下的泵（28）。

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