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    • 1. 发明授权
    • Artificial blood vessel
    • 人造血管
    • US5549664A
    • 1996-08-27
    • US236694
    • 1994-05-02
    • Yoshimi HirataNoriaki KanekoMasahiro MoriwakiKanetake Oura
    • Yoshimi HirataNoriaki KanekoMasahiro MoriwakiKanetake Oura
    • A61F2/06A61L27/28A61L27/48A61L27/50A61L27/56
    • A61L27/56A61F2/06A61L27/28A61L27/48A61L27/507
    • An artificial blood vessel which has excellent long-term patency and can be used stably in a living body for a long time. The artificial blood vessel has improved durability under pulsation and can withstand puncturing. The artificial blood vessel is made of an elastomer containing a multiplicity of cells throughout the structure thereof and comprises a layer (A) containing closed cells having no communicability therebetween; and a layer (B) containing open cells having mutual communicability therebetween. The surface of the layer (B) which is contiguous to the inner surface of the layer (A) and the wall surfaces of the open cells are coated with a thin film of crosslinked protein of biological origin. The layer (A) may be incorporated with a knitted or woven fabric which is not degradable in a living body. The layer (B) may further contain a synthetic resin short fiber distributed throughout the layer.
    • 一种人造血管,具有优异的长期通畅性,可长期稳定地用于生物体。 人造血管在脉动下具有改善的耐久性并且可以承受穿刺。 人造血管由其整个结构中含有多个细胞的弹性体制成,并且包括含有闭孔的层(A),其间没有通信性; 以及包含其间具有相互通信性的开放细胞的层(B)。 与层(A)的内表面邻接的层(B)的表面和开孔的壁表面涂覆有生物来源的交联蛋白质的薄膜。 层(A)可以与在生物体中不可降解的针织或机织织物结合。 层(B)还可以包含分布在整个层中的合成树脂短纤维。