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1. 发明申请

US20100142780A1 OPTICAL IMAGE MEASURING DEVICE, OPTICAL IMAGE MEASURING PROGRAM, FUNDUS OBSERVATION DEVICE, AND FUNDUS OBSERVATION PROGRAM 有权
标题翻译：光学图像测量设备，光学图像测量程序，基金观察设备和基金观察程序
公开(公告)号：US20100142780A1
公开(公告)日：2010-06-10
申请号：US11545270
申请日：2006-10-10
申请人： Yoshiaki Yasuno , Toyohiko Yatagai , Yasufumi Fukuma , Hisashi Tsukada , Tsutomu Kikawa , Hiroyuki Aoki , Takashi Fujimura
发明人： Yoshiaki Yasuno , Toyohiko Yatagai , Yasufumi Fukuma , Hisashi Tsukada , Tsutomu Kikawa , Hiroyuki Aoki , Takashi Fujimura
IPC分类号： G06K9/00
CPC分类号： G01N21/4795 , A61B3/102 , A61B3/145 , G01N2021/1787
摘要： An optical image measuring device which can form a highly reliable image even if an object moves during scanning of a signal light is provided. An optical image forming device 1 comprises: an interferometer that splits a low coherence light L0 into a signal light LS and a reference light LR and generates an interference light LC by overlaying the signal light LS reflected by a fundus oculi with the reference light LR reflected by a reference mirror 14; a CCD 34 which receives the interference light LC and outputs a detection signal; Galvanometer mirrors 22 and 23 to scan the signal light LS in a main scanning direction and a sub-scanning direction; and a computer 40 forming tomographic images G1 to Gm along the main scanning direction at different positions of the sub-scanning direction. The Galvanometer mirrors 22 and 23 scan the signal light LS in a given direction crossing the main scanning direction, and the computer 40 forms a tomographic image for correction GR along the given direction to correct displacement of each topographic image Gi based on the tomographic image for correction GR.
摘要翻译：提供了即使在信号光的扫描期间物体移动时也可以形成高可靠性图像的光学图像测量装置。光学图像形成装置1包括：干涉仪，其将低相干光L0分解成信号光LS和参考光LR，并通过将由眼底反射的信号光LS与反射的参考光LR重叠而产生干涉光LC 通过参考反射镜14; CCD34，其接收干涉光LC并输出检测信号; 电流计镜22和23在主扫描方向和副扫描方向扫描信号光LS; 以及在副扫描方向的不同位置沿着主扫描方向形成断层图像G1〜Gm的计算机40。电流计反射镜22和23沿与主扫描方向相交的给定方向扫描信号光LS，并且计算机40沿着给定方向形成用于校正GR的断层图像，以校正基于断层图像的每个地形图像Gi的位移校正GR。

2. 发明授权

US07756311B2 Optical image measuring device, optical image measuring program, fundus observation device, and fundus observation program 有权
标题翻译：光学图像测量装置，光学图像测量程序，眼底观察装置和眼底观察程序
公开(公告)号：US07756311B2
公开(公告)日：2010-07-13
申请号：US11545270
申请日：2006-10-10
申请人： Yoshiaki Yasuno , Toyohiko Yatagai , Yasufumi Fukuma , Hisashi Tsukada , Tsutomu Kikawa , Hiroyuki Aoki , Takashi Fujimura
发明人： Yoshiaki Yasuno , Toyohiko Yatagai , Yasufumi Fukuma , Hisashi Tsukada , Tsutomu Kikawa , Hiroyuki Aoki , Takashi Fujimura
IPC分类号： G06K9/00 , G01B9/02
CPC分类号： G01N21/4795 , A61B3/102 , A61B3/145 , G01N2021/1787
摘要： An optical image measuring device which can form a highly reliable image even if an object moves during scanning of a signal light is provided. An optical image forming device 1 comprises: an interferometer that splits a low coherence light L0 into a signal light LS and a reference light LR and generates an interference light LC by overlaying the signal light LS reflected by a fundus oculi with the reference light LR reflected by a reference mirror 14; a CCD 34 which receives the interference light LC and outputs a detection signal; Galvanometer mirrors 22 and 23 to scan the signal light LS in a main scanning direction and a sub-scanning direction; and a computer 40 forming tomographic images G1 to Gm along the main scanning direction at different positions of the sub-scanning direction. The Galvanometer mirrors 22 and 23 scan the signal light LS in a given direction crossing the main scanning direction, and the computer 40 forms a tomographic image for correction GR along the given direction to correct displacement of each topographic image Gi based on the tomographic image for correction GR.
摘要翻译：提供了即使在信号光的扫描期间物体移动时也可以形成高可靠性图像的光学图像测量装置。光学图像形成装置1包括：干涉仪，其将低相干光L0分解成信号光LS和参考光LR，并通过将由眼底反射的信号光LS与反射的参考光LR重叠而产生干涉光LC 通过参考反射镜14; CCD34，其接收干涉光LC并输出检测信号; 电流计镜22和23在主扫描方向和副扫描方向扫描信号光LS; 以及在副扫描方向的不同位置沿着主扫描方向形成断层图像G1〜Gm的计算机40。电流计反射镜22和23沿与主扫描方向相交的给定方向扫描信号光LS，并且计算机40沿着给定方向形成用于校正GR的断层图像，以校正基于断层图像的每个地形图像Gi的位移校正GR。

3. 发明授权

US07710577B2 Multiplexing spectrum interference optical coherence tomography 有权
标题翻译：多重频谱干涉光学相干断层扫描
公开(公告)号：US07710577B2
公开(公告)日：2010-05-04
申请号：US11572803
申请日：2005-03-17
申请人： Toyohiko Yatagai , Yoshiaki Yasuno
发明人： Toyohiko Yatagai , Yoshiaki Yasuno
IPC分类号： G01B9/02 , G01B11/02
CPC分类号： G01B9/02044 , G01B9/02028 , G01B9/02078 , G01B9/02091 , G01B2290/70 , G01N21/4795
摘要： The present invention achieves multiplexing spectrum interference optical coherence tomography capable of full-range OCT measurement that causes no delays in measurement time due to high-order scans and is also free from complex conjugated images. This multiplexing spectrum interference optical coherence tomography comprises: a first beam splitter 3 positioned in an optical path 2 from a light source 1 and used to separate an object light 4 and a reference light 5; a galvano mirror 6 positioned in the optical path of the object light 4 and used to scan the object light onto a measured object 8; a second beam splitter 10 positioned in the optical path of the reference light 5; a first reference mirror 12 positioned in the optical path of a first reference light 11 separated by the second beam splitter 10; a second reference mirror 15 positioned in the optical path of a second reference light 13 separated by the second beam splitter 10; and a chopper 16 that passes the first reference light 11 and second reference light 13 alternately.
摘要翻译：本发明实现了能够进行全范围OCT测量的复用频谱干涉光学相干断层摄影，其不会由于高阶扫描而导致测量时间的延迟，并且也没有复杂的共轭图像。该多路复用频谱干涉光学相干断层摄影包括：第一分束器3，其位于光源1的光路2中，用于分离物体光4和基准光5; 位于物体光4的光路中并用于将物体光扫描到测量对象8上的电流镜6; 位于参考光5的光路中的第二分束器10; 位于由第二分束器10分离的第一参考光11的光路中的第一参考反射镜12; 位于由第二分束器10分离的第二参考光13的光路中的第二参考镜15; 以及交替地使第一基准光11和第二参照光13通过的斩波器16。

4. 发明申请

US20090079993A1 Dental Optical Coherence Tomograph 有权
标题翻译：牙科光学相干断层扫描仪
公开(公告)号：US20090079993A1
公开(公告)日：2009-03-26
申请号：US12085423
申请日：2006-11-22
申请人： Toyohiko Yatagai , Yoshiaki Yasuno , Masami Tamura
发明人： Toyohiko Yatagai , Yoshiaki Yasuno , Masami Tamura
IPC分类号： G01B11/02
CPC分类号： G01N21/4795 , A61B5/0062 , A61B5/0066 , A61B5/0088 , A61B5/7257 , A61C13/0004 , G01B9/02004 , G01B9/02007 , G01B9/0205 , G01B9/02088 , G01B9/02091 , G01B11/2441 , G01B2290/70
摘要： A dental optical coherence tomography apparatus for measuring tissue in a stomatognathic region of a living body or an artificial composition in the stomatognathic region as a measured object includes: a variable wavelength light source (15); a light splitting portion (19) that splits light-source light emitted from the variable wavelength light source (15) into reference light (29) and measuring light (28); an interference portion (19) that causes the measuring light (28) and the reference light (29) to interfere with each other, thereby generating interference light; a photodetection portion (41) that measures the interference light; and an arithmetic portion (27b) that generates an image of a measured object (22) by Fourier transforming or inverse Fourier transforming the intensity of the interference light, whose wavelength changes with time, that has been detected by the photodetection portion for each of the wavelengths. Accordingly, an optical coherence tomography apparatus applicable to dental measurement can be provided.
摘要翻译：一种用于测量作为测量对象的口腔身体区域中的生物体的口腔特征区域中的组织或人造组合物的牙科用光学相干断层摄影装置，包括：可变波长光源（15）; 将从所述可变波长光源（15）发射的光源光分解为参考光（29）和测量光（28）的光分离部（19）; 使测量光（28）和参考光（29）彼此干涉的干涉部分（19），从而产生干涉光; 测量干涉光的光电检测部分（41）; 以及算术部（27b），其通过傅里叶变换或傅立叶逆变换波长随时间变化的波长随时间变化的干涉光的强度来生成测量对象（22）的图像，所述干涉光的强度由光电检测部分检测到波长。因此，可以提供适用于牙齿测量的光学相干断层摄影装置。

5. 发明申请

US20080002183A1 Multiplexing Spectrum Interference Optical Coherence Tomography 有权
标题翻译：多重光谱干涉光学相干断层扫描
公开(公告)号：US20080002183A1
公开(公告)日：2008-01-03
申请号：US11572803
申请日：2005-03-17
申请人： Toyohiko Yatagai , Yoshiaki Yasuno
发明人： Toyohiko Yatagai , Yoshiaki Yasuno
IPC分类号： G01N21/00 , G01B9/02 , G01J3/28
CPC分类号： G01B9/02044 , G01B9/02028 , G01B9/02078 , G01B9/02091 , G01B2290/70 , G01N21/4795
摘要： The present invention achieves multiplexing spectrum interference optical coherence tomography capable of full-range OCT measurement that causes no delays in measurement time due to high-order scans and is also free from complex conjugated images. This multiplexing spectrum interference optical coherence tomography comprises: a first beam splitter 3 positioned in an optical path 2 from a light source 1 and used to separate an object light 4 and a reference light 5; a galvano mirror 6 positioned in the optical path of the object light 4 and used to scan the object light onto a measured object 8; a second beam splitter 10 positioned in the optical path of the reference light 5; a first reference mirror 12 positioned in the optical path of a first reference light 11 separated by the second beam splitter 10; a second reference mirror 15 positioned in the optical path of a second reference light 13 separated by the second beam splitter 10; and a chopper 16 that passes the first reference light 11 and second reference light 13 alternately.
摘要翻译：本发明实现了能够进行全范围OCT测量的复用频谱干涉光学相干断层摄影，其不会由于高阶扫描而导致测量时间的延迟，并且也没有复杂的共轭图像。该多路复用频谱干涉光学相干断层摄影包括：第一分束器3，其位于光源1的光路2中，用于分离物体光4和基准光5; 位于物体光4的光路中并用于将物体光扫描到测量对象8上的电流镜6; 位于参考光5的光路中的第二分束器10; 位于由第二分束器10分离的第一参考光11的光路中的第一参考反射镜12; 位于由第二分束器10分离的第二参考光13的光路中的第二参考镜15; 以及交替地使第一基准光11和第二参照光13通过的斩波器16。

6. 发明授权

US07823782B2 Dental optical coherence tomograph 有权
标题翻译：牙科光学相干断层扫描仪
公开(公告)号：US07823782B2
公开(公告)日：2010-11-02
申请号：US12085423
申请日：2006-11-22
申请人： Toyohiko Yatagai , Yoshiaki Yasuno , Masami Tamura
发明人： Toyohiko Yatagai , Yoshiaki Yasuno , Masami Tamura
IPC分类号： G06K7/10
CPC分类号： G01N21/4795 , A61B5/0062 , A61B5/0066 , A61B5/0088 , A61B5/7257 , A61C13/0004 , G01B9/02004 , G01B9/02007 , G01B9/0205 , G01B9/02088 , G01B9/02091 , G01B11/2441 , G01B2290/70
摘要： A dental optical coherence tomography apparatus for measuring tissue in a stomatognathic region of a living body or an artificial composition in the stomatognathic region as a measured object includes: a variable wavelength light source (15); a light splitting portion (19) that splits light-source light emitted from the variable wavelength light source (15) into reference light (29) and measuring light (28); an interference portion (19) that causes the measuring light (28) and the reference light (29) to interfere with each other, thereby generating interference light; a photodetection portion (41) that measures the interference light; and an arithmetic portion (27b) that generates an image of a measured object (22) by Fourier transforming or inverse Fourier transforming the intensity of the interference light, whose wavelength changes with time, that has been detected by the photodetection portion for each of the wavelengths. Accordingly, an optical coherence tomography apparatus applicable to dental measurement can be provided.
摘要翻译：一种用于测量作为测量对象的口腔身体区域中的生物体的口腔特征区域中的组织或人造组合物的牙科用光学相干断层摄影装置，包括：可变波长光源（15）; 将从所述可变波长光源（15）发射的光源光分解为参考光（29）和测量光（28）的光分离部（19）; 使测量光（28）和参考光（29）彼此干涉的干涉部分（19），从而产生干涉光; 测量干涉光的光电检测部分（41）; 以及算术部（27b），其通过傅里叶变换或傅立叶逆变换波长随时间变化的波长随时间变化的干涉光的强度来生成测量对象（22）的图像，所述干涉光的强度由光电检测部分检测到波长。因此，可以提供适用于牙齿测量的光学相干断层摄影装置。

7. 发明授权

US06741356B1 Method for detecting physical amount of object and optical apparatus using the same 有权
标题翻译：用于检测物体的物理量的方法及使用其的光学装置
公开(公告)号：US06741356B1
公开(公告)日：2004-05-25
申请号：US09664723
申请日：2000-09-19
申请人： Hiroshi Ishiwata , Toyohiko Yatagai , Masahide Itoh
发明人： Hiroshi Ishiwata , Toyohiko Yatagai , Masahide Itoh
IPC分类号： G01B902
CPC分类号： G01B9/04 , G01B9/02024 , G01B9/02087 , G01B2290/70 , G02B21/14
摘要： A detection apparatus includes a differential interference contrast microscope, a device for changing the amount of retardation between the two polarized components, a device for photographing the image of an object to be observed, and a device for performing a calculation with respect to the image captured by this photographing device. In the detection apparatus, amounts of retardation between two polarized components split in an illumination optical system of the differential interference contrast microscope are detected to form two differential interference contrast images relative to the object in which the amounts of retardation between the polarized components are equal, but have different signs. Subsequently, in the two differential interference contrast images, a differential calculation and a summed calculation are performed with regard to respective corresponding pixels to obtain a differential image and a summed image. The ratio of image information between the differential image and the summed image is calculated, and from the result of this calculation, image information in a predetermined range is extracted. In this way, the phase of the object can be detected.
摘要翻译：检测装置包括差分干涉对比显微镜，用于改变两个偏振分量之间的延迟量的装置，用于拍摄待观察对象的图像的装置和用于对所捕获的图像进行计算的装置通过该拍摄装置。在检测装置中，检测在微分干涉对比显微镜的照明光学系统中分离的两个偏振分量之间的延迟量，以相对于偏振分量之间的相位量相等的对象形成两个差分干涉对比图像，但有不同的迹象。随后，在两个差分干涉对比图像中，针对各个对应的像素执行差分计算和相加计算，以获得差分图像和相加图像。计算差分图像和求和图像之间的图像信息的比率，并从该计算结果中提取预定范围内的图像信息。以这种方式，可以检测物体的相位。

8. 发明授权

US5969855A Microscope apparatus 失效
标题翻译：显微镜装置
公开(公告)号：US5969855A
公开(公告)日：1999-10-19
申请号：US729410
申请日：1996-10-11
申请人： Hiroshi Ishiwata , Toyohiko Yatagai , Masahide Itoh
发明人： Hiroshi Ishiwata , Toyohiko Yatagai , Masahide Itoh
IPC分类号： G02B21/14 , G02B21/36 , G02B21/06
CPC分类号： G02B21/367 , G02B21/14
摘要： A microscope apparatus that has an electronic image pickup device arranged on an image surface of an imaging optical system, a component for separating light from a light source into two portions, a device for changing a phase difference between the two portions of light, a device for storing information on the images picked up by the image pickup device, and information processor for processing the information of images. The images are picked up by the electronic image pickup device as the phase difference is changed, and the information on the images is multiplied by a periodic function, as a weight function, which is given the phase difference as variable, and a resultant product is integrated so that a differential interference microscope apparatus capable of accurately obtaining a phase distribution of the object or a phase-contrast microscope apparatus capable of effectively enhancing a resolving power without lowering an image contrast is obtained.
摘要翻译：一种具有配置在摄像光学系统的图像表面上的电子摄像装置的显微镜装置，将光源从光源分离成两部分的部件，用于改变两部分光之间的相位差的装置，用于存储由图像拾取装置拾取的图像的信息，以及用于处理图像信息的信息处理器。当相位差改变时，由电子摄像装置拾取图像，并将关于图像的信息乘以周期函数作为加权函数，其给出相位差作为可变，并且得到的乘积为可以获得能够精确地获得物体的相位分布的微分干涉显微镜装置，或能够有效地提高分辨能力而不降低图像对比度的相位差显微镜装置。

9. 发明授权

US09612193B2 Ellipsometry system 有权
公开(公告)号：US09612193B2
公开(公告)日：2017-04-04
申请号：US14130694
申请日：2012-07-09
申请人： Toyohiko Yatagai , Cense J. Abraham
发明人： Toyohiko Yatagai , Cense J. Abraham
IPC分类号： G01N21/21 , A61B3/10 , G01B9/02 , G01N21/47 , G02B5/30 , G01J4/00 , G02B5/04
CPC分类号： G01N21/211 , A61B3/102 , G01B9/02044 , G01B9/02091 , G01B2290/45 , G01B2290/70 , G01J4/00 , G01N21/4795 , G02B5/04 , G02B5/3083
摘要： An ellipsometry system and a detection unit thereof are capable of achieving miniaturization and price reduction associated therewith. The ellipsometry system includes the detection unit that: has an optical polarization element; separates an interference polarization beam obtained by causing the object-reflected polarization beam and reference reflected polarization beam to interfere with each other into a plurality of interference polarization beams on a wavelength basis; and detects the respective separated polarization components in each wavelength. The optical polarization element: has a birefringence characteristic including a first refractive index and a second refractive index; receives the separated interference polarization beams of the respective wavelengths in a wavelength order and in a parallel manner; separates the separated interference polarization beam of each wavelength, on a polarization component basis, while transmitting the same, and outputs the respective separated polarization components in each wavelength in the same direction but along different optical axes.

10. 发明授权

US09039175B2 Three-dimensional retina image generation device 有权
标题翻译：三维视网膜图像生成装置
公开(公告)号：US09039175B2
公开(公告)日：2015-05-26
申请号：US13388075
申请日：2010-08-03
申请人： Toyohiko Yatagai , Cense J. Abraham
发明人： Toyohiko Yatagai , Cense J. Abraham
IPC分类号： A61B3/14 , A61B3/10 , A61B3/12
CPC分类号： A61B3/1225 , A61B3/102
摘要： An optical coherence eye-fundus tomography device has a high resolution and a good operability, as well as be miniaturized and be produced at a low cost. The optical coherence eye-fundus tomography device includes: a light source unit which emits a source light beam; a reference-light unit which reflects a reference light beam; an inspection unit which illuminates an object with an object scanning light beam, reflected the object scanning light beam; and a detection unit which obtains a tomographic image of the object on the basis of the interference light beam produced by interfering the reflected reference light beam with the reflected object light beam. For example, the light source unit emits the outgoing light beam that has a depth of focus of not less than 300 μm, and resolution that is 6 μm×6 μm or higher in a planar direction perpendicular to a traveling direction of the outgoing light beam.
摘要翻译：光学相干眼底层析成像装置具有高分辨率和良好的可操作性，并且小型化并以低成本生产。光学相干眼底断层摄影装置包括：发射源光束的光源单元; 反射参考光束的参考光单元; 用物体扫描光束照射物体的检查单元，反射物体扫描光束; 以及检测单元，其基于通过将反射的参考光束与反射的物体光束干涉而产生的干涉光获得物体的断层图像。例如，光源单元发射焦深不小于300μm的出射光束，并且在垂直于出射光束的行进方向的平面方向上发射6μm×6μm以上的分辨率。

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