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1. 发明申请

US20100317853A1 NOVEL IMATINIB CAMSYLATE AND METHOD FOR PREPARING THEREOF 审中-公开
标题翻译：新型樟脑磺酸钠及其制备方法
公开(公告)号：US20100317853A1
公开(公告)日：2010-12-16
申请号：US12525962
申请日：2008-02-01
申请人： Yoon Seok Oh , Jae Kyung Lim , Dong Hyuk Shin , Seung Kyoo Seong , Sang Ho Lee , Hak Soo Lee , Eun Hee Cho , Jei Man Ryu
发明人： Yoon Seok Oh , Jae Kyung Lim , Dong Hyuk Shin , Seung Kyoo Seong , Sang Ho Lee , Hak Soo Lee , Eun Hee Cho , Jei Man Ryu
IPC分类号： C07D401/14
CPC分类号： C07D401/04
摘要： The present invention relates to a novel imatinib camsylate and a method for preparing the same. Imatinib camsylate according to the present invention has a faster absorption rate and higher absorption concentration in terms of pharmacokinetics, and further has excellent water solubility, as compared to commercially available imatinib mesylate.
摘要翻译：本发明涉及新颖的伊马替尼樟脑磺酸盐及其制备方法。与市售的甲磺酸伊马替尼相比，本发明的伊马替尼樟脑磺酸盐在药代动力学方面具有更快的吸收速率和更高的吸收浓度，并且还具有优异的水溶性。

2. 发明申请

US20080200526A1 Composition for the Prevention and Treatment of Allergic Inflammatory Disease 审中-公开
标题翻译：用于预防和治疗过敏性炎症的组合物
公开(公告)号：US20080200526A1
公开(公告)日：2008-08-21
申请号：US11631762
申请日：2005-07-05
申请人： Jin Soo Lee , Sae Kwang Ku , Sang Ho Lee , Jei Man Ryu
发明人： Jin Soo Lee , Sae Kwang Ku , Sang Ho Lee , Jei Man Ryu
IPC分类号： A61K31/426 , A61P29/00
CPC分类号： A61K31/426
摘要： Disclosed herein is a composition for the treatment and prevention of allergic inflammatory diseases comprising N-hydroxy-4-{5-[4-(5-isopropyl-2-methyl-1,3-thiazol-4-yl)phenoxy]pentoxy}-benzamidine, 4-{5-[4-(5-isopropyl-2-methyl-1,3-thiazol-4-yl)phenoxy]pentoxy}-benzamidine or pharmaceutically acceptable salts. The composition exhibits excellent medicinal effects on allergic inflammatory diseases, with a great reduction in typical chronic inflammation symptoms, such as an increase of eosinophil level in bronchoalveolar lavage fluid, total leukocyte level and eosinophil level in blood, the hypertrophy or hyperplasia of bronchial epithelium due to an increase in the number of mucus cells, a reduction in alveolar surface area resulting from the hyptertrophy of alveolar walls, and the infiltration of inflammatory cells.
摘要翻译：本文公开了用于治疗和预防过敏性炎性疾病的组合物，其包含N-羟基-4- {5- [4-（5-异丙基-2-甲基-1,3-噻唑-4-基）苯氧基]戊氧基} - 苯甲脒，4- {5- [4-（5-异丙基-2-甲基-1,3-噻唑-4-基）苯氧基]戊氧基} - 苄脒或其药学上可接受的盐。该组合物对过敏性炎性疾病表现出优异的药用效果，典型的慢性炎症症状大大减少，如支气管肺泡灌洗液中嗜酸性粒细胞水平的增加，血液中的总白细胞水平和嗜酸性粒细胞水平，支气管上皮的肥大或增生增加粘液细胞的数量，由肺泡壁的低渗引起的肺泡表面积的减少和炎性细胞的浸润。

3. 发明授权

US11141403B2 Benzimidazoles and indoles as taro inhibitors 有权
公开(公告)号：US11141403B2
公开(公告)日：2021-10-12
申请号：US16061481
申请日：2016-12-13
申请人： MERCK SHARP & DOHME CORP. , John P. Caldwell , Ginny Dai Ho , Sookhee N. Ha , Sandra J. Koseoglu , Marc A. Labroli , Sang Ho Lee , Christina Madsen-Duggan , Mihir Mandal , Jianping Pan , Weidong Pan , Terry Roemer , Jing Su , Christopher Michael Tan , Zheng Tan , Hao Wang , Christine Yang , Shu-Wei Yang
发明人： John P. Caldwell , Ginny Dai Ho , Sookhee N. Ha , Sandra J. Koseoglu , Marc A. Labroli , Sang Ho Lee , Christina Madsen-Duggan , Mihir Mandal , Jianping Pan , Weidong Pan , Terry Roemer , Jing Su , Christopher Michael Tan , Zheng Tan , Hao Wang , Christine Yang , Shu-Wei Yang
IPC分类号： A61K31/397 , A61P31/04 , A61K31/407 , C07D235/08 , C07D401/04 , C07D401/14 , C07D403/04 , C07D403/06 , C07D471/04
摘要： Novel compounds of the structural formula I, and the pharmaceutically acceptable salts thereof, are inhibitors of TarO and may be useful in the prevention, treatment and suppression of diseases mediated by TarO, such as bacterial infections, including gram negative bacterial infections and gram positive bacterial infections such as MRSA and MRSE, alone or in combination with a β-lactam antibiotic.

4. 发明授权

US08762721B2 Method for generating authorization key and method for negotiating authorization in communication system based on frequency overlay 有权
标题翻译：基于频率叠加的通信系统协商授权密钥生成方法
公开(公告)号：US08762721B2
公开(公告)日：2014-06-24
申请号：US12670519
申请日：2008-06-12
申请人： Sun-Hwa Lim , Sang Ho Lee
发明人： Sun-Hwa Lim , Sang Ho Lee
IPC分类号： H04W12/04
CPC分类号： H04L9/0844 , H04L63/062 , H04L63/0892 , H04L2209/80 , H04W12/04
摘要： A method for a terminal including a first media access control (MAC) layer and a second MAC layer to create an authorization key includes performing a first network entry process to a base station through the first MAC layer, and performing a second network entry process for a frequency overlay to the base station through the second MAC layer. In this instance, the first network entry process includes acquiring a key for generating an authorization key through an authentication process according to an authentication method negotiated with the base station, and generating a first authorization key through the key for generating the authorization key. The second network entry process includes generating a second authorization key by using the key generated in the first network entry process for generating the authorization key.
摘要翻译：一种包括第一媒体接入控制（MAC）层和第二MAC层以创建授权密钥的终端的方法包括：通过第一MAC层对基站执行第一网络进入过程，并且执行第二网络进入处理，通过第二MAC层对基站的频率覆盖。在这种情况下，第一网络进入处理包括通过根据与基站协商的认证方法的认证处理来获取用于生成授权密钥的密钥，以及通过用于生成授权密钥的密钥生成第一授权密钥。第二网络进入处理包括通过使用在第一网络进入处理中生成的密钥来生成授权密钥来产生第二授权密钥。

5. 发明授权

US08660053B2 Method for receiving and transmitting MBMS service, terminal for receiving MBMS service, and network for transmitting MBMS service 有权
标题翻译：接收和发送MBMS服务的方法，用于接收MBMS服务的终端和用于发送MBMS服务的网络
公开(公告)号：US08660053B2
公开(公告)日：2014-02-25
申请号：US13335834
申请日：2011-12-22
申请人： Jee Hyeon Na , Dae Ik Kim , Chul Park , Sang Ho Lee
发明人： Jee Hyeon Na , Dae Ik Kim , Chul Park , Sang Ho Lee
IPC分类号： H04H20/71 , H04W4/00
CPC分类号： H04W4/06 , H04L5/0007 , H04L5/0087 , H04L5/0094 , H04W48/16 , H04W88/08
摘要： Disclosed is a method for receiving MBMS services from a base station supporting multi-carriers, including: receiving first system information including information on all the carriers; receiving second system information including information on multi-carriers supported by the base station; receiving MBMS control information through an MBMS control channel; and receiving the MBMS services through an MBMS transmission channel based on the MBMS control information.
摘要翻译：公开了一种从支持多载波的基站接收MBMS业务的方法，包括：接收包含所有载波信息的第一系统信息; 接收包括由所述基站支持的多载波信息的第二系统信息; 通过MBMS控制信道接收MBMS控制信息; 以及基于MBMS控制信息通过MBMS传输信道接收MBMS服务。

6. 发明授权

US08649312B2 Method and apparatus for counting multimedia broadcast and multicast services 失效
标题翻译：多媒体广播和组播服务计费方法和装置
公开(公告)号：US08649312B2
公开(公告)日：2014-02-11
申请号：US13330629
申请日：2011-12-19
申请人： Dae Ik Kim , Jee Hyeon Na , Jung Mo Moon , Sang Ho Lee
发明人： Dae Ik Kim , Jee Hyeon Na , Jung Mo Moon , Sang Ho Lee
IPC分类号： H04H20/71 , G06F11/00
CPC分类号： H04W4/06
摘要： A method and apparatus for multimedia broadcast and multicast service (MBMS) counting is provided. A user equipment (UE) may transmit selected service information to a multi-cell and multicast coordination entity (MCE) through a target evolved node base station (eNB), every time that a service requiring counting is received or cancelled and thus, the MCE may accurately manage a number of UEs that receive a service for each eNB. Also, the use may transmit selected service information to the MCE through the target eNB every time that the UE enters a new cell and thus, the MCE may accurately manage a number of UEs that receive a service for each eNB.
摘要翻译：提供了一种用于多媒体广播和多播服务（MBMS）计数的方法和装置。每当接收或取消需要计数的服务时，用户设备（UE）可以通过目标演进节点基站（eNB）向多小区和多播协调实体（MCE）发送所选择的服务信息，因此，MCE 可以准确地管理为每个eNB接收服务的多个UE。此外，每当UE进入新小区时，使用可以通过目标eNB将选定的服务信息发送到MCE，因此，MCE可以准确地管理为每个eNB接收服务的UE的数量。

7. 发明申请

US20130203726A1 FtsZ INHIBITORS AS POTENTIATORS OF BETA-LACTAM ANTIBIOTICS AGAINST METHICILLIN-RESISTANT STAPHYLOCOCCUS 审中-公开
标题翻译： FtsZ抑制剂作为抗甲氧西林硫杆菌抗菌素抗肿瘤药物的潜力
公开(公告)号：US20130203726A1
公开(公告)日：2013-08-08
申请号：US13583480
申请日：2011-03-04
申请人： Terry Roemer , Sang Ho Lee , Lisa Wang Jarantow
发明人： Terry Roemer , Sang Ho Lee , Lisa Wang Jarantow
IPC分类号： A61K31/545 , A61K31/397 , A61K31/4025 , A61K31/437
CPC分类号： A61K31/545 , A61K31/198 , A61K31/397 , A61K31/4025 , A61K31/407 , A61K31/43 , A61K31/437 , A61K45/06 , A61K2300/00
摘要： The present invention relates to the use of inhibitors of FtsZ, an ancestral tubulin of prokaryotes, to restore susceptibility to β-lactam antibiotics, including carbapenems and cephalosporins, particularly in methicillin-resistant Staphylococcus aureus (MRSA), methicillin-resistant Staphyloccus epidermis (MRSE), and other coagulase negative staphylococci (MRCNS).
摘要翻译：本发明涉及使用原核生物的祖先微管蛋白FtsZ的抑制剂来恢复对β-内酰胺类抗生素（包括碳青霉烯类和头孢菌素）的敏感性，特别是耐甲氧西林金黄色葡萄球菌（MRSA），甲氧西林耐药性葡萄球菌表皮（MRSE））和其他凝固酶阴性葡萄球菌（MRCNS）。

8. 发明授权

US08280401B2 Method of managing paging group 有权
标题翻译：管理寻呼组的方法
公开(公告)号：US08280401B2
公开(公告)日：2012-10-02
申请号：US12676455
申请日：2008-08-25
申请人： Jee Hyeon Na , Sang Ho Lee
发明人： Jee Hyeon Na , Sang Ho Lee
IPC分类号： H04W64/00 , H04W68/00
CPC分类号： H04W68/02
摘要： The present invention relates to a method of managing a paging group in a mobile terminal that is in an idle mode. A method of managing a paging group according to an exemplary embodiment of the invention includes: collecting paging group ID information including paging group levels and local IDs; determining, on the basis of the collected paging group ID information, whether or not a location update occurs; and if it is determined that the location update occurs, comparing a location update cycle according to a location update time with a threshold value, selecting a paging group level on the basis of the comparison result, and selecting a paging group corresponding to the selected paging group level.
摘要翻译：本发明涉及管理处于空闲模式的移动终端中的寻呼组的方法。根据本发明的示例性实施例的管理寻呼组的方法包括：收集包括寻呼组级别和本地ID的寻呼组ID信息; 基于所收集的寻呼组ID信息确定是否发生位置更新; 并且如果确定位置更新发生，则根据位置更新时间与阈值比较位置更新周期，基于比较结果选择寻呼组级别，并且选择与所选寻呼相对应的寻呼组组级别。

9. 发明申请

US20110260882A1 METHOD AND APPARATUS FOR PROXIMITY SENSING OF A PORTABLE TERMINAL 审中-公开
标题翻译：便携式终端接近感测的方法和装置
公开(公告)号：US20110260882A1
公开(公告)日：2011-10-27
申请号：US13091543
申请日：2011-04-21
申请人： Kwang Yeol Lee , Dong Won Han , Sang Ho Lee
发明人： Kwang Yeol Lee , Dong Won Han , Sang Ho Lee
IPC分类号： G08B21/00
CPC分类号： H04M1/72577 , H04M2250/12
摘要： A proximity sensing method of a portable terminal and a proximity sensing apparatus thereof are provided. The proximity sensing method of a portable terminal with an illumination sensor includes determining an output of the illumination sensor, determining that the portable terminal is proximate to an object when the output of the illumination sensor has a set pattern, and determining that the portable terminal is not proximate to the object when the output of the illumination sensor does not the set pattern. The proximity sensing method of a portable terminal may support a proximity sensing function using an illumination sensor instead of a proximity sensor to reduce a manufacturing cost of the portable terminal. In addition, since the method does not need a separate proximity sensor, it may address a lack of mounting space problem.
摘要翻译：提供了便携式终端的接近感测方法及其接近感测装置。具有照明传感器的便携式终端的接近感测方法包括确定照明传感器的输出，当照明传感器的输出具有设定模式时，确定便携式终端接近物体，并且确定便携式终端是当照明传感器的输出不是设定模式时，不靠近物体。便携式终端的接近感测方法可以使用照明传感器代替接近传感器来支持接近感测功能，以降低便携式终端的制造成本。另外，由于该方法不需要单独的接近传感器，所以可能解决了安装空间问题的缺乏。

10. 发明申请

US20110192396A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CHRONIC OBSTRUCTIVE PULMONARY DISEASE 审中-公开
标题翻译：用于预防或治疗慢性阻塞性肺疾病的药物组合物
公开(公告)号：US20110192396A1
公开(公告)日：2011-08-11
申请号：US13123481
申请日：2009-10-09
申请人： Sun Mee Yang , Kwon Jo Lim , Hyun Jin Park , Il Hwan Kim , Sang Ho Lee , Jong Wook Lee
发明人： Sun Mee Yang , Kwon Jo Lim , Hyun Jin Park , Il Hwan Kim , Sang Ho Lee , Jong Wook Lee
IPC分类号： A61M11/00 , A61K38/22 , A61P11/00 , A61P11/08 , A61M15/00
CPC分类号： A61K38/1808
摘要： Provided is a pharmaceutical composition for preventing or treating mucus hypersecretion in airways or chronic obstructive pulmonary diseases (COPDs), the pharmaceutical composition including an epidermal growth factor (EGF) and a pharmaceutically acceptable carrier. In addition, a combined preparation capable of respectively administering the pharmaceutical composition and chemotherapeutics is provided.
摘要翻译：提供了用于预防或治疗气道或慢性阻塞性肺疾病（COPD）中的粘液分泌过多的药物组合物，所述药物组合物包括表皮生长因子（EGF）和药学上可接受的载体。另外，提供能够分别施用药物组合物和化学治疗剂的组合制剂。

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