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1. 发明授权

US10874125B2 Method for improving the cooking quality of brown rice by lactic acid bacteria fermentation 有权
公开(公告)号：US10874125B2
公开(公告)日：2020-12-29
申请号：US15891386
申请日：2018-02-08
申请人： Yongfu Li , Xin Cheng , Feng Shi , Li Wang , Zhengxing Chen , Yanan Li , Ren Wang , Xiaohu Luo , Juan Li
发明人： Yongfu Li , Xin Cheng , Feng Shi , Li Wang , Zhengxing Chen , Yanan Li , Ren Wang , Xiaohu Luo , Juan Li
IPC分类号： A23L7/104 , A23L7/10
CPC分类号： A23L7/104 , A23L7/115 , A23V2002/00 , A23V2002/00 , A23Y2220/67
摘要： The invention discloses a method for improving the cooking and eating quality of brown rice by using Lactic acid bacteria fermentation, which belongs to the technical field of food processing. The method comprises the steps of mixing activated lactic acid bacteria with water and brown rice, loading the mixture into a one-way outgassing container, removing excess air or filling up the container, and sealing the container and performing fermentation. The invention is very simple and easy to operate, and has very low energy consumption. It is suitable to be up scaled for industrial production and will significantly promote brown rice to become a staple food.

2. 发明申请

US20180338514A1 Method for Improving the Cooking Quality of Brown Rice by Lactic Acid Bacteria Fermentation 审中-公开
公开(公告)号：US20180338514A1
公开(公告)日：2018-11-29
申请号：US15891386
申请日：2018-02-08
申请人： Yongfu Li , Xin Cheng , Feng Shi , Li Wang , Zhengxing Chen , Yanan Li , Ren Wang , Xiaohu Luo , Juan Li
发明人： Yongfu Li , Xin Cheng , Feng Shi , Li Wang , Zhengxing Chen , Yanan Li , Ren Wang , Xiaohu Luo , Juan Li
IPC分类号： A23L7/104 , A23L7/10
摘要： The invention discloses a method for improving the cooking and eating quality of brown rice by using Lactic acid bacteria fermentation, which belongs to the technical field of food processing. The method comprises the steps of mixing activated lactic acid bacteria with water and brown rice, loading the mixture into a one-way outgassing container, removing excess air or filling up the container, and sealing the container and performing fermentation. The invention is very simple and easy to operate, and has very low energy consumption. It is suitable to be up scaled for industrial production and will significantly promote brown rice to become a staple food.

3. 发明申请

US20090075205A1 Aqueous developable benzocyclobutene-based polymer composition and method of use of such compositions 有权
标题翻译：水性可显影的苯并环丁烯类聚合物组合物及其组合物的使用方法
公开(公告)号：US20090075205A1
公开(公告)日：2009-03-19
申请号：US11665246
申请日：2005-10-12
申请人： Ying Hung So , Edmund J. Stark , Shellene K. Thurston , Kayla J. Gallant (nee Baranck) , Yongfu Li
发明人： Ying Hung So , Edmund J. Stark , Shellene K. Thurston , Kayla J. Gallant (nee Baranck) , Yongfu Li
IPC分类号： G03F7/004 , G03F7/027
CPC分类号： C08K5/23 , C08K5/42 , G03F7/0226 , G03F7/0233 , G03F7/075 , G03F7/40 , C08L45/00
摘要： The invention is a composition comprising a curable arylcyclobutene based oligomer or polymer and a dissolution inhibitor which comprises a compound comprising at least two diazonaphthoquinone (DNQ) moieties each of which is pendant from different phenyl groups.
摘要翻译：本发明是一种包含可固化的芳族环烯基低聚物或聚合物和一种溶解抑制剂的组合物，其包含包含至少两个重氮萘醌（DNQ）部分的化合物，每个重氮萘醌（DNQ）部分是不同苯基的侧链。

4. 发明公开

US20230373936A1 COMPOSITION OF A LIPOPHILIC AGENT FOR SOLUTION PHASE SYNTHESIS OF BIOMOLECULES 审中-公开
公开(公告)号：US20230373936A1
公开(公告)日：2023-11-23
申请号：US17748292
申请日：2022-05-19
申请人： Yongfu Li
发明人： Yongfu Li
IPC分类号： C07D251/54 , C07D471/04 , C07K1/04
CPC分类号： C07D251/54 , C07D471/04 , C07K1/042
摘要： Disclosed is a lipophilic agent comprising a triazine core having lipophilic groups for organic synthesis. The lipophilic agent soluble in one system of solvent(s) wherein the lipophilic agent is participated in a chemical reaction but insoluble by adding a miscible poor solvent to change solution composition after the reaction completes. The lipophilic agent facilitates process improvement wherein practical operation only involves mixing with reactants in solution followed by precipitating with change of solution composition followed by filtering to obtain the precipitated solid, simplifying the purification by isolating the desired solid. The operation is reproducible along the progress in a multi-step synthesis, allowing pure intermediates and pure product as a solid to be rapidly obtained with ease and certainty. This invention can thus accelerate research and development of pharmaceutical biomolecules, representing a tremendous step forward for boosting productivity and greening chemical industry.

5. 外观设计

USD1001702S1 Sunshade 有权
公开(公告)号：USD1001702S1
公开(公告)日：2023-10-17
申请号：US29895320
申请日：2023-06-20
申请人： Yongfu Li
设计人： Yongfu Li
摘要： FIG. 1 is a front, right and top perspective view of a sunshade, showing my design.
FIG. 2 is a rear, left and bottom perspective view thereof.
FIG. 3 is a front elevation view thereof.
FIG. 4 is a rear elevation view thereof.
FIG. 5 is a left side elevation view thereof.
FIG. 6 is a right side elevation view thereof.
FIG. 7 is a top plan view thereof.
FIG. 8 is a bottom plan view thereof.
FIG. 9 is an enlarged view of detail 9 in FIG. 1.
FIG. 10 is an enlarged view of detail 10 in FIG. 2.
FIG. 11 is an enlarged view of detail 11 in FIG. 2; and,
FIG. 12 is an enlarged view of detail 12 in FIG. 2.
The broken lines depict portions of the sunshade that form no part of the claimed design.
The dot-dash broken lines in FIGS. 1, 2, 9, 10, 11 and 12 depict the boundaries of the enlargements that form no part of the claimed design.

6. 发明授权

US09850383B2 Uncharged pyrenyloxy sulfonamide dyes for conjugation with biomolecules 有权
公开(公告)号：US09850383B2
公开(公告)日：2017-12-26
申请号：US14998651
申请日：2016-01-27
申请人： Yongfu Li
发明人： Yongfu Li
IPC分类号： C07H19/20 , C09B57/00 , G01N21/64
CPC分类号： C09B57/001 , G01N21/6486
摘要： The invention relates to novel fluorescent dyes based on the following pyrenyloxy sulfonamide structure: wherein R1 is a leash joined to the pyrenyloxy group via an ether link containing generally a reactive functional group such as, activated carbonate, activated ester, amino group, azide or alkyne for conjugation with biomolecules; R2 and R3 are hydrogen atoms, or short alkyl chains, or cyclic rings with or without heteroatoms such as nitrogen, oxygen, sulfur, phosphorus. The spectral properties of the fluorescent dyes are sufficiently different in wave-lengths and intensity from fluorescein as to permit simultaneous use of fluorescein and/or more other fluorescent dyes with minimum interference and to avoid interference from endogenous green fluorescent protein in biological system. The dyes are non-ionic to facilitate their entry into cells for intracellular detection. The non-ionic structure also precludes undesired electrostatic reactions with ionic sites on biological components and structures. The dyes have bigger Stokes' shifts than other dyes with similar spectral properties allowing use of simpler, more efficient detection equipment, are not sensitive to pH, and have good solubility in aqueous solution.

7. 发明申请

US20070027280A1 Multifunctional substituted monomers and polyarylene compositions therefrom 审中-公开
标题翻译：多功能取代单体和聚亚芳基组合物
公开(公告)号：US20070027280A1
公开(公告)日：2007-02-01
申请号：US10549381
申请日：2004-04-01
申请人： Jerry Hahnfeld , Robert Hefner , Yongfu Li , Q. Niu
发明人： Jerry Hahnfeld , Robert Hefner , Yongfu Li , Q. Niu
IPC分类号： C08F38/00
CPC分类号： C08F38/00 , C08G61/12 , C08G61/123 , C08G61/125 , C08G61/126 , C08L65/00
摘要： A compound useful in the formation of polymeric dielectric films for semiconductor devices and the resulting cured films and devices, said compound comprising i) three or more dienophile groups (A-functional groups) and ii) a single ring structure comprising two conjugated carbon-to-carbon double bonds and a leaving group L (collectively referred to as a B-functional group), characterized in that one A-functional group of one molecule of the compound is capable of reaction under cycloaddition reaction conditions with the B-functional group of a second molecule and elimination of the leaving group L, to thereby form a polymer.
摘要翻译：一种可用于形成半导体器件的聚合物电介质膜和所得固化膜和器件的化合物，所述化合物包括i）三个或更多个亲双烯体基团（A-官能团）和ii）单环结构，其包含两个共轭碳 - 碳双键和离去基团L（统称为B官能团），其特征在于，一分子化合物的一个A官能团能够在环加成反应条件下与B官能团反应第二分子和离去基团L的消除，从而形成聚合物。

8. 外观设计

USD1001698S1 Sunshade 有权
公开(公告)号：USD1001698S1
公开(公告)日：2023-10-17
申请号：US29894628
申请日：2023-06-12
申请人： Yongfu Li
设计人： Yongfu Li
摘要： FIG. 1 is a front, right and top perspective view of a sunshade, showing my design.
FIG. 2 is a rear, right and bottom perspective view thereof.
FIG. 3 is a rear, right and top perspective view thereof.
FIG. 4 is a front elevation view thereof.
FIG. 5 is a rear elevation view thereof.
FIG. 6 is a left side elevation view thereof.
FIG. 7 is a right side elevation view thereof.
FIG. 8 is a top plan view thereof.
FIG. 9 is a top plan view thereof.
FIG. 10 is an enlarged view of detail 10 in FIG. 1.
FIG. 11 is an enlarged view of detail 11 in FIG. 2; and,
FIG. 12 is an enlarged view of detail 12 in FIG. 2.
The broken lines depict portions of the sunshade that form no part of the claimed design.
The dot-dash broken lines in FIGS. 1, 2 10, 11 and 12 depict the boundaries of the enlargements that form no part of the claimed design.

9. 发明申请

US20170210904A1 Uncharged pyrenyloxy sulfonamide dyes for conjugation with biomolecules 审中-公开
公开(公告)号：US20170210904A1
公开(公告)日：2017-07-27
申请号：US14998651
申请日：2016-01-27
申请人： Yongfu Li
发明人： Yongfu Li
IPC分类号： C09B57/00 , G01N21/64
CPC分类号： C09B57/001 , G01N21/6486
摘要： The invention relates to novel fluorescent dyes based on the following pyrenyloxy sulfonamide structure: wherein R1 is a leash joined to the pyrenyloxy group via an ether link containing generally a reactive functional group such as, activated carbonate, activated ester, amino group, azide or alkyne for conjugation with biomolecules; R2 and R3 are hydrogen atoms, or short alkyl chains, or cyclic rings with or without heteroatoms such as nitrogen, oxygen, sulfur, phosphorus. The spectral properties of the fluorescent dyes are sufficiently different in wave-lengths and intensity from fluorescein as to permit simultaneous use of fluorescein and/or more other fluorescent dyes with minimum interference and to avoid interference from endogenous green fluorescent protein in biological system. The dyes are non-ionic to facilitate their entry into cells for intracellular detection. The non-ionic structure also precludes undesired electrostatic reactions with ionic sites on biological components and structures. The dyes have bigger Stokes' shifts than other dyes with similar spectral properties allowing use of simpler, more efficient detection equipment, are not sensitive to pH, and have good solubility in aqueous solution.

10. 发明公开

US20230357763A1 Morpholinos with Increased Delivery Efficiency 审中-公开
公开(公告)号：US20230357763A1
公开(公告)日：2023-11-09
申请号：US17803316
申请日：2022-05-06
申请人： James E. Summerton , Yongfu Li , Shan Jiang , Daniel Bryce Summerton
发明人： James E. Summerton , Yongfu Li , Shan Jiang , Daniel Bryce Summerton
IPC分类号： C12N15/113
CPC分类号： C12N15/113 , C12N2310/11 , C12N2310/3233 , C12N2310/3513 , C12N2310/51 , C12N2320/30
摘要： Morpholino antisense oligos (Morpholinos) are a class of synthetic non-ionic molecules, each designed to very specifically bind to a selected complementary RNA sequence (targeted RNA transcript). Custom-sequence Morpholinos are used in a broad range of biological research areas, as well as for therapeutic applications in vivo (in living animals such as humans).
For most in vivo applications the “bare” Morpholino (FIG. 1a) is linked to a cationic delivery component to give a “delivery-enabled” Morpholino (FIG. 1b) with significantly improved delivery efficiency. However, cytosolic delivery was still markedly less than expected. Then recently we discovered that by adding a special disconnect component between the Morpholino component and the cationic delivery component (FIG. 1c), the cytosolic delivery efficiency for the Morpholino was dramatically increased (about a 1,000% increase in delivery efficiency).
This patent application describes designing, making, and using such delivery-enabled Morpholinos containing a key disconnect component.

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