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1. 发明申请

US20120064519A1 SYSTEM AND METHOD FOR DUAL-DETECTION OF A CELLULAR RESPONSE 审中-公开
标题翻译：用于双重检测细胞响应的系统和方法
公开(公告)号：US20120064519A1
公开(公告)日：2012-03-15
申请号：US13300029
申请日：2011-11-18
申请人： Ye Fang , Ann M. Ferrie , Joydeep Lahiri , Deepti J. Mudaliar , Qi Wu
发明人： Ye Fang , Ann M. Ferrie , Joydeep Lahiri , Deepti J. Mudaliar , Qi Wu
IPC分类号： C12Q1/68 , G01N33/566 , C12Q1/02
CPC分类号： G01N21/648 , G01N21/7743
摘要： A system and method as defined herein for dual-detection of evanescent-wave label-free light and evanescent-wave excited-fluorescent label-emitted light in an optical biosensor.
摘要翻译：本文所定义的系统和方法，用于在光学生物传感器中双重检测ev逝波无标记光和ev逝波激发荧光标记发射光。

2. 发明申请

US20090325211A1 System and method for dual-detection of a cellular response 审中-公开
标题翻译：用于双重检测细胞反应的系统和方法
公开(公告)号：US20090325211A1
公开(公告)日：2009-12-31
申请号：US12151179
申请日：2008-05-05
申请人： Ye Fang , Ann M. Ferrie , Joydeep Lahiri , Deepti J. Mudaliar , Qi Wu
发明人： Ye Fang , Ann M. Ferrie , Joydeep Lahiri , Deepti J. Mudaliar , Qi Wu
IPC分类号： C12Q1/02 , C12M1/34
CPC分类号： G01N21/648 , G01N21/7743
摘要： A system and method as defined herein for dual-detection of evanescent-wave label-free light and evanescent-wave excited-fluorescent label-emitted light in an optical biosensor.
摘要翻译：本文所定义的系统和方法，用于在光学生物传感器中双重检测ev逝波无标记光和ev逝波激发荧光标记发射光。

3. 发明授权

US08703428B2 Single-cell label-free assay 失效
标题翻译：单细胞无标记检测
公开(公告)号：US08703428B2
公开(公告)日：2014-04-22
申请号：US12128267
申请日：2008-05-28
申请人： Ye Fang , Ann M. Ferrie , Qi Wu
发明人： Ye Fang , Ann M. Ferrie , Qi Wu
IPC分类号： G01N33/53 , C12N1/00 , C12N5/00 , C12N5/02 , G01N33/567
CPC分类号： G01N33/5008 , G01N21/211 , G01N21/553 , G01N21/554 , G01N33/54373
摘要： The disclosure provides a system and method for characterizing a single live-cell response to a stimulus with a biosensor imaging system having cells immobilized on the biosensor at a resolution level of a single cell, as defined herein.
摘要翻译：本公开提供了一种系统和方法，用于利用具有如本文所定义的单个细胞的分辨率水平固定在生物传感器上的细胞的生物传感器成像系统来表征对刺激的单个活细胞响应。

4. 发明申请

US20090093013A1 Single-Cell Label-Free Assay 失效
标题翻译：单细胞标记免疫测定
公开(公告)号：US20090093013A1
公开(公告)日：2009-04-09
申请号：US12128267
申请日：2008-05-28
申请人： Ye Fang , Ann M. Ferrie , Qi Wu
发明人： Ye Fang , Ann M. Ferrie , Qi Wu
IPC分类号： C12Q1/02
CPC分类号： G01N33/5008 , G01N21/211 , G01N21/553 , G01N21/554 , G01N33/54373
摘要： The disclosure provides a system and method for characterizing a single live-cell response to a stimulus with a biosensor imaging system having cells immobilized on the biosensor at a resolution level of a single cell, as defined herein.
摘要翻译：本公开提供了一种系统和方法，用于利用具有如本文所定义的单个细胞的分辨率水平固定在生物传感器上的细胞的生物传感器成像系统来表征对刺激的单个活细胞响应。

5. 发明申请

US20100129856A1 Methods and Devices for Cell Signaling Under Pulse Stimulation 审中-公开
标题翻译：脉冲刺激下细胞信号传导的方法和装置
公开(公告)号：US20100129856A1
公开(公告)日：2010-05-27
申请号：US12624062
申请日：2009-11-23
申请人： Ye Fang , Vasiliy Nikolaevich Goral , Joydeep Lahiri , Deepti Jayaraman Mudaliar , Elizabeth Tran , Qi Wu
发明人： Ye Fang , Vasiliy Nikolaevich Goral , Joydeep Lahiri , Deepti Jayaraman Mudaliar , Elizabeth Tran , Qi Wu
IPC分类号： C12Q1/02 , C12M1/34
CPC分类号： G01N15/06 , G01N21/553 , G01N21/774 , G01N2015/0693
摘要： The disclosure provides a device for measuring cellular responses under controlled environments. The disclosure also provides an array of devices for measuring cellular responses under controlled environments. The disclosure also provides methods to study cell signaling using the devices. By using microfluidics, the disclosure enables study of cell signaling under well-defined environment conditions. Such capability can be used for differentiating long-acting ligands from short-acting ligands, for determining the kinetics of receptor resensitization and functional recovery of receptor signaling, and for differentiating the sensitivity of a cell type to laminar flow-induced stress force. Through combination with conventional static label-free cell assays, the full spectrum of a drug compound can be studied in details, thus creating a complete representation of its pharmacology acting on living cells.
摘要翻译：本公开提供了一种用于在受控环境下测量细胞反应的装置。本公开还提供了用于在受控环境下测量细胞反应的装置阵列。本公开还提供了使用该装置研究细胞信号传导的方法。通过使用微流体，本公开使得能够在明确的环境条件下研究细胞信号。这种能力可以用于区分长效配体的长效配体，用于确定受体复苏的功能恢复和受体信号的功能恢复的动力学，以及区分细胞类型对层流引起的应力的敏感性。通过与常规静态无标记细胞测定法的组合，可以详细研究药物化合物的全谱，从而创建其作用于活细胞的药理学的完整表示。

6. 外观设计

USD970380S1 Watchband 有权
公开(公告)号：USD970380S1
公开(公告)日：2022-11-22
申请号：US29787783
申请日：2021-06-08
申请人： Qi Wu
设计人： Qi Wu

7. 发明授权

US08718161B2 Method for transmitting pilot signal in multi-carrier wireless transmission system 有权
标题翻译：在多载波无线传输系统中发送导频信号的方法
公开(公告)号：US08718161B2
公开(公告)日：2014-05-06
申请号：US13497786
申请日：2010-09-16
申请人： Hai Wang , Kaushik Josiam , Qi Wu , Zhouyue Pi
发明人： Hai Wang , Kaushik Josiam , Qi Wu , Zhouyue Pi
IPC分类号： H04K1/10
CPC分类号： H04L5/0048 , H04L5/0023
摘要： The present invention provides a method for transmitting pilots in a multi-carrier wireless transmission system. A wireless time-frequency transmission block is composed of N consecutive OFDM symbols in time domain and M consecutive physical sub-carriers in frequency domain, N and M are integers those are greater than or equal to 1. The method includes: partitioning the wireless time-frequency transmission block into several areas, and determining the position of pilots, of which the total number is a preset number, according to the time-frequency domain balancing principle of pilots of various antennas in various areas; inserting pilots at the pilot positions of each antenna corresponding to the antenna for transmission. In accordance with the present invention, the simultaneous transmission of multiple antennas is supported in a wireless time-frequency transmission block of a multi-carrier wireless transmission system.
摘要翻译：本发明提供一种在多载波无线传输系统中发送导频的方法。无线时频传输块由时域中的N个连续OFDM符号和频域中的M个连续物理子载波组成，N和M是大于或等于1的整数。该方法包括：将无线时间根据各个领域的各种天线的导频的时频平衡原理，确定导频的位置，其总数为预设编号; 在与天线相对应的每个天线的导频位置处插入导频以进行传输。根据本发明，在多载波无线传输系统的无线时频传输块中支持多个天线的同时传输。

8. 发明授权

US08611585B2 Clear path detection using patch approach 有权
标题翻译：使用补丁方法清除路径检测
公开(公告)号：US08611585B2
公开(公告)日：2013-12-17
申请号：US12581766
申请日：2009-10-19
申请人： Wende Zhang , Qi Wu , Tsuhan Chen
发明人： Wende Zhang , Qi Wu , Tsuhan Chen
IPC分类号： G06K9/00 , G01C21/00
CPC分类号： G06K9/4609 , B60W2420/42 , G06K9/00798 , G06K9/00805
摘要： A method for detecting a clear path of travel for a vehicle utilizing an image generated by a camera device located upon the vehicle includes monitoring the image, and generating a plurality of patches onto the image, wherein the patches are collectively arranged to substantially include the clear path of travel. Feature extraction is utilized to analyze the patches and includes convolving each of the patches with a feature detection filter generating a feature-based filter response, extracting features based upon the feature-based filter response, and determining each of the patches to represent the clear path of travel or to not represent the clear path of travel based upon the extracted features. The clear path of travel is determined based upon the plurality of patches, and is utilized to navigate the vehicle.
摘要翻译：用于利用位于车辆上的照相机装置生成的图像来检测车辆的清晰行驶路径的方法包括监视图像，并在图像上生成多个贴片，其中所述贴片被集体布置成基本上包括清晰的旅行路线使用特征提取来分析补丁，并且包括使用生成基于特征的过滤器响应的特征检测过滤器对每个补丁进行卷积，基于基于特征的过滤器响应来提取特征，以及确定每个补丁以表示清除路径的旅行或不代表基于提取的特征的明确的旅行路径。基于多个补片确定行驶的清晰路径，并且用于导航车辆。

9. 发明授权

US08411932B2 Example-based two-dimensional to three-dimensional image conversion method, computer readable medium therefor, and system 有权
标题翻译：基于示例的二维至三维图像转换方法，其计算机可读介质和系统
公开(公告)号：US08411932B2
公开(公告)日：2013-04-02
申请号：US12351187
申请日：2009-01-09
申请人： Kai-Che Liu , Fu-Chiang Jan , Wen-Chao Chen , Cheng-Feng Wu , Tsu-Han Chen , Qi Wu
发明人： Kai-Che Liu , Fu-Chiang Jan , Wen-Chao Chen , Cheng-Feng Wu , Tsu-Han Chen , Qi Wu
IPC分类号： G06K9/00 , G06K9/32 , G06K9/34 , G06T15/40
CPC分类号： H04N13/261 , H04N13/128 , H04N2213/003
摘要： An example-based 2D to 3D image conversion method, a computer readable medium therefore, and a system are provided. The embodiments are based on an image database with depth information or with which depth information can be generated. With respect to a 2D image to be converted into 3D content, a matched background image is found from the database. In addition, graph-based segmentation and comparison techniques are employed to detect the foreground of the 2D image so that the relative depth map can be generated from the foreground and background information. Therefore, the 3D content can be provided with the 2D image plus the depth information. Thus, users can rapidly obtain the 3D content from the 2D image automatically and the rendering of the 3D content can be achieved.
摘要翻译：提供了一种基于示例的2D至3D图像转换方法，因此提供了计算机可读介质和系统。实施例基于具有深度信息的图像数据库或可以生成哪个深度信息。对于要转换为3D内容的2D图像，从数据库中找到匹配的背景图像。此外，采用基于图的分割和比较技术来检测2D图像的前景，从而可以从前景和背景信息生成相对深度图。因此，3D内容可以提供2D图像加上深度信息。因此，用户可以自动从2D图像快速获得3D内容，并可以实现3D内容的渲染。

10. 发明授权

US08400551B2 High resolution label free imaging 有权
标题翻译：高分辨率无标签成像
公开(公告)号：US08400551B2
公开(公告)日：2013-03-19
申请号：US13021945
申请日：2011-02-07
申请人： Qi Wu
发明人： Qi Wu
IPC分类号： G02B13/16 , H04N5/225
CPC分类号： G01N21/7743 , G01N21/553
摘要： An apparatus having an optical reader system and method for label-independent detection having improved spatial resolution of the reader, as defined herein. The system includes an optical configuration for interrogating a sensor on a microplate at an incident angle (θ1) of greater than 45°, and recording the image received from the contacted sensor with the image recorder, the image recorder being oriented with respect to the reflected beam at a reflected angle (θ2) of greater than about 5°, as further defined herein.
摘要翻译：具有如本文所定义的具有改进的读取器的空间分辨率的用于标签独立检测的光学读取器系统和方法的装置。该系统包括用于以大于45°的入射角度（＆amp; 1）在微孔板上询问传感器的光学配置，并且将从接触传感器接收的图像记录到图像记录器，图像记录器相对于反射光束的反射角（θ）大于约5°，如本文进一步定义。

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