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2. 发明申请

US20060057220A1 Fine spherical particles with satisfactory molecular orientation, spherical microcapsules comprising the same and processes for producing these 审中-公开
标题翻译：具有令人满意的分子取向性的球形微粒，包含其的球形微胶囊及其制备方法
公开(公告)号：US20060057220A1
公开(公告)日：2006-03-16
申请号：US10530198
申请日：2003-10-02
申请人： Yoko Matsuzawa , Mutsuyoshi Matsumoto , Masaki Kogiso , Toshimi Shimizu
发明人： Yoko Matsuzawa , Mutsuyoshi Matsumoto , Masaki Kogiso , Toshimi Shimizu
IPC分类号： A61K38/10 , A61K38/08 , A61K9/50 , A61K9/16
CPC分类号： A61K8/11 , A61K8/64 , A61K47/6925 , A61K2800/412 , A61Q19/00 , B01J13/02
摘要： The present invention relates to a fine spherical particle having uniform molecular orientation having uniform molecular orientation, which is useful in fine chemical fields or electronic and information fields, such as a functional material and a medical material, using membrane formation of a bicephalic compound; a spherical microcapsule encapsulating a hydrophilic core substance; and a process for producing the same. The fine spherical particle can be produced by immersing a substrate having hydrophilicity in an aqueous solution of a salt of the compound represented by the following formula (1) to precipitate the fine particle under an acidic atmosphere. wherein R represents a hydrogen atom or an alkyl group having 1 to 5 carbon atoms; n is an integer of 8 to 20; and m is an integer of 1 to 3. The spherical microcapsule encapsulating a fine particle of a hydrophilic core substance is produced by immersing a substrate having hydrophilicity in an aqueous solution in which a metal salt of the compound represented by formula (1) and the hydrophilic core substance are dissolved; and allowing the aqueous solution to stand under an acidic atmosphere to precipitate the fine particle. The resulting fine spherical particle and the spherical microcapsule has a particle diameter of 0.01 to 100 μm.
摘要翻译：本发明涉及具有均匀分子取向的均匀分子取向的细球形颗粒，其可用于精细化学领域或电子信息领域，例如功能材料和医疗材料，其使用双头齿化合物的膜形成; 包封亲水核心物质的球形微胶囊; 及其制造方法。可以通过将具有亲水性的基材浸渍在由下式（1）表示的化合物的盐的水溶液中，在酸性气氛下使细颗粒沉淀而制造。其中R表示氢原子或具有1至5个碳原子的烷基; n为8〜20的整数， m为1〜3的整数。通过将具有亲水性的基材浸渍在式（1）表示的化合物的金属盐和式（1）表示的化合物的水溶液中，将亲水性核物质的微粒包封的球形微胶囊亲水核心物质溶解; 并使该水溶液在酸性气氛下放置，使细颗粒沉淀。得到的细球形粒子和球形微胶囊的粒径为0.01〜100μm。

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