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1. 发明授权

US06855706B2 Phenylalanine derivatives 失效
标题翻译：苯丙氨酸衍生物
公开(公告)号：US06855706B2
公开(公告)日：2005-02-15
申请号：US10150067
申请日：2002-05-20
申请人： Yasuhiro Tanaka , Toshihiko Yoshimura , Hiroyuki Izawa , Chieko Ejima , Mitsuhiko Kojima , Yuko Satake , Eiji Nakanishi , Nobuyasu Suzuki , Shingo Makino , Manabu Suzuki , Masahiro Murata
发明人： Yasuhiro Tanaka , Toshihiko Yoshimura , Hiroyuki Izawa , Chieko Ejima , Mitsuhiko Kojima , Yuko Satake , Eiji Nakanishi , Nobuyasu Suzuki , Shingo Makino , Manabu Suzuki , Masahiro Murata
IPC分类号： A61P1/04 , A61P3/10 , A61P9/00 , A61P9/10 , A61P11/06 , A61P17/06 , A61P19/02 , A61P29/00 , A61P35/00 , A61P35/04 , A61P37/06 , A61P37/08 , A61P43/00 , C07C235/74 , C07C275/42 , C07C311/08 , C07C311/10 , C07C311/13 , C07C311/16 , C07C311/21 , C07C311/29 , C07C311/44 , C07C317/44 , C07C323/25 , C07C323/60 , C07C323/62 , C07C335/22 , C07D207/12 , C07D207/14 , C07D207/16 , C07D239/38 , C07D239/42 , C07D295/185 , C07C233/47 , A61K31/198 , A61K31/40 , C07C233/63 , C07C233/81
CPC分类号： C07D239/42 , C07C235/74 , C07C275/42 , C07C311/08 , C07C311/10 , C07C311/13 , C07C311/16 , C07C311/21 , C07C311/29 , C07C311/44 , C07C317/44 , C07C323/25 , C07C323/60 , C07C323/62 , C07C335/22 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2601/16 , C07C2601/18 , C07C2602/08 , C07C2602/42 , C07D207/12 , C07D207/14 , C07D207/16 , C07D239/38 , C07D295/185
摘要： Specified phenylalanine derivatives and analogues thereof have an antagonistic activity to α 4 integrin. They are used as therapeutic agents for various diseases concerning α 4 integrin.
摘要翻译：指定的苯丙氨酸衍生物及其类似物对α4整联蛋白具有拮抗作用。它们被用作关于α4整联蛋白的各种疾病的治疗剂。

2. 发明申请

US20050070485A1 Phenylalanine derivatives 失效
标题翻译：苯丙氨酸衍生物
公开(公告)号：US20050070485A1
公开(公告)日：2005-03-31
申请号：US10986829
申请日：2004-11-15
申请人： Yasuhiro Tanaka , Toshihiko Yoshimura , Hiroyuki Izawa , Chieko Ejima , Mitsuhiko Kojima , Yuko Satake , Eiji Nakanishi , Nobuyasu Suzuki , Shingo Makino , Manabu Suzuki , Masahiro Murata
发明人： Yasuhiro Tanaka , Toshihiko Yoshimura , Hiroyuki Izawa , Chieko Ejima , Mitsuhiko Kojima , Yuko Satake , Eiji Nakanishi , Nobuyasu Suzuki , Shingo Makino , Manabu Suzuki , Masahiro Murata
IPC分类号： A61P1/04 , A61P3/10 , A61P9/00 , A61P9/10 , A61P11/06 , A61P17/06 , A61P19/02 , A61P29/00 , A61P35/00 , A61P35/04 , A61P37/06 , A61P37/08 , A61P43/00 , C07C235/74 , C07C275/42 , C07C311/08 , C07C311/10 , C07C311/13 , C07C311/16 , C07C311/21 , C07C311/29 , C07C311/44 , C07C317/44 , C07C323/25 , C07C323/60 , C07C323/62 , C07C335/22 , C07D207/12 , C07D207/14 , C07D207/16 , C07D239/38 , C07D239/42 , C07D295/185 , A61K38/04
CPC分类号： C07D239/42 , C07C235/74 , C07C275/42 , C07C311/08 , C07C311/10 , C07C311/13 , C07C311/16 , C07C311/21 , C07C311/29 , C07C311/44 , C07C317/44 , C07C323/25 , C07C323/60 , C07C323/62 , C07C335/22 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2601/16 , C07C2601/18 , C07C2602/08 , C07C2602/42 , C07D207/12 , C07D207/14 , C07D207/16 , C07D239/38 , C07D295/185
摘要： Specified phenylalanine derivatives and analogues thereof have an antagonistic activity to α4 integrin. They are used as therapeutic agents for various diseases concerning α4 integrin.
摘要翻译：指定的苯丙氨酸衍生物及其类似物对α4整联蛋白具有拮抗作用。它们被用作关于α4整联蛋白的各种疾病的治疗剂。

3. 发明授权

US07160874B2 Phenylalanine derivatives 失效
标题翻译：苯丙氨酸衍生物
公开(公告)号：US07160874B2
公开(公告)日：2007-01-09
申请号：US10986829
申请日：2004-11-15
申请人： Yasuhiro Tanaka , Toshihiko Yoshimura , Hiroyuki Izawa , Chieko Ejima , Mitsuhiko Kojima , Yuko Satake , Eiji Nakanishi , Nobuyasu Suzuki , Shingo Makino , Manabu Suzuki , Masahiro Murata
发明人： Yasuhiro Tanaka , Toshihiko Yoshimura , Hiroyuki Izawa , Chieko Ejima , Mitsuhiko Kojima , Yuko Satake , Eiji Nakanishi , Nobuyasu Suzuki , Shingo Makino , Manabu Suzuki , Masahiro Murata
IPC分类号： C07C233/47 , C07C233/63 , C07C233/81 , A61K31/198 , C07D279/12
CPC分类号： C07D239/42 , C07C235/74 , C07C275/42 , C07C311/08 , C07C311/10 , C07C311/13 , C07C311/16 , C07C311/21 , C07C311/29 , C07C311/44 , C07C317/44 , C07C323/25 , C07C323/60 , C07C323/62 , C07C335/22 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2601/16 , C07C2601/18 , C07C2602/08 , C07C2602/42 , C07D207/12 , C07D207/14 , C07D207/16 , C07D239/38 , C07D295/185
摘要： Specified phenylalanine derivatives and analogues thereof have an antagonistic activity to α4 integrin. They are used as therapeutic agents for various diseases concerning α4 integrin.
摘要翻译：指定的苯丙氨酸衍生物及其类似物对α4整联蛋白具有拮抗作用。它们被用作关于α4整联蛋白的各种疾病的治疗剂。

4. 发明授权

US06610710B2 Phenylalanine derivatives 失效
标题翻译：苯丙氨酸衍生物
公开(公告)号：US06610710B2
公开(公告)日：2003-08-26
申请号：US10183729
申请日：2002-06-28
申请人： Yasuhiro Tanaka , Toshihiko Yoshimura , Chieko Ejima , Mitsuhiko Kojima , Eiji Nakanishi , Hiroyuki Izawa , Yuko Satake , Nobuyasu Suzuki , Manabu Suzuki , Masahiro Murata
发明人： Yasuhiro Tanaka , Toshihiko Yoshimura , Chieko Ejima , Mitsuhiko Kojima , Eiji Nakanishi , Hiroyuki Izawa , Yuko Satake , Nobuyasu Suzuki , Manabu Suzuki , Masahiro Murata
IPC分类号： A01N4340
CPC分类号： C07D295/185 , C07C233/63 , C07C243/36 , C07C311/21 , C07C311/46 , C07C323/40 , C07C2601/14 , C07D205/04 , C07D207/12 , C07D207/14 , C07D211/46 , C07D211/58 , C07D211/62 , C07D217/06 , C07D233/52 , C07D239/38 , C07D285/06 , C07D295/32
摘要： Phenylalanine derivatives of the following formula and analogues thereof have an antagonistic activity to &agr;4&bgr;7 integrin and a selectivity toward &agr;4&bgr;1 integrin. They are used as therapeutic agents for various diseases to which &agr;4&bgr;7 integrin relates.
摘要翻译：下式的苯丙氨酸衍生物及其类似物对α4β7整联蛋白具有拮抗作用和对α4β1整联蛋白的选择性。它们被用作α4β7整联蛋白涉及的各种疾病的治疗剂。

5. 发明授权

US07902179B2 Heterocyclic compounds 有权
标题翻译：杂环化合物
公开(公告)号：US07902179B2
公开(公告)日：2011-03-08
申请号：US10475097
申请日：2002-04-26
申请人： Yasuhiro Tanaka , Kohichi Fujita , Yoshitomo Chujoh , Syunsuke Fukuda , Yuka Ikenoue , Tomoyuki Tagami , Akira Chiba , Ariko Kodaira , Hideki Matsumoto , Tadakiyo Nakagawa , Tatsuhiro Yamada , Manabu Suzuki , Masahiro Murata
发明人： Yasuhiro Tanaka , Kohichi Fujita , Yoshitomo Chujoh , Syunsuke Fukuda , Yuka Ikenoue , Tomoyuki Tagami , Akira Chiba , Ariko Kodaira , Hideki Matsumoto , Tadakiyo Nakagawa , Tatsuhiro Yamada , Manabu Suzuki , Masahiro Murata
IPC分类号： A61K31/44
CPC分类号： C07D471/04 , A61K31/437 , Y02A50/411
摘要： A pharmaceutical composition containing a heterocyclic compound of the formula (I) wherein each symbol is as defined in the specification, an isomer thereof, a solvate thereof or a pharmaceutically acceptable salt thereof as an active ingredient has a superior TNF-α production suppressing action. Accordingly, it is useful for the prophylaxis or treatment of various diseases caused by abnormal production of TNF-α.
摘要翻译：含有式（I）的杂环化合物的药物组合物，其中每个符号如说明书中所定义，其异构体，其溶剂化物或其药学上可接受的盐作为活性成分具有优异的TNF-α产生抑制作用。因此，可以预防或治疗由TNF-α异常产生引起的各种疾病。

6. 发明申请

US20050250796A1 Heterocyclic compounds 失效
标题翻译：杂环化合物
公开(公告)号：US20050250796A1
公开(公告)日：2005-11-10
申请号：US11116310
申请日：2005-04-28
申请人： Tatsuhiro Yamada , Tadakiyo Nakagawa , Yasuhiro Tanaka , Kohichi Fujita , Tomoyuki Tagami , Yuka Ikenoue , Shunsuke Fukuda , Yoshitomo Chujo , Manabu Suzuki , Masahiro Murata
发明人： Tatsuhiro Yamada , Tadakiyo Nakagawa , Yasuhiro Tanaka , Kohichi Fujita , Tomoyuki Tagami , Yuka Ikenoue , Shunsuke Fukuda , Yoshitomo Chujo , Manabu Suzuki , Masahiro Murata
IPC分类号： A61K31/519 , A61P1/00 , A61P1/04 , A61P29/00 , A61P31/04 , A61P37/02 , A61P37/06 , A61P43/00 , C07D471/04 , C07D471/02 , A61K31/4745
CPC分类号： C07D471/04 , A61K31/519
摘要： The inventive subject matter relates to compounds, pharmaceutical compositions, and kits containing a heterocyclic compound represented by the formula (I) wherein R is an alkyl group optionally having substituent(s) etc., X is an amino group optionally having substituent(s), Y1 and Y2 are nitrogen atoms etc., an isomer or solvate thereof or a pharmaceutically acceptable salt thereof as an active ingredient.
摘要翻译：本发明涉及包含式（I）表示的杂环化合物的化合物，药物组合物和试剂盒，其中R是任选具有取代基的烷基等。X是任选具有取代基的氨基， Y 1和Y 2是氮原子等，其异构体或溶剂合物或其药学上可接受的盐作为活性成分。

7. 发明授权

US07279484B2 Heterocyclic compounds 失效
标题翻译：杂环化合物
公开(公告)号：US07279484B2
公开(公告)日：2007-10-09
申请号：US11116310
申请日：2005-04-28
申请人： Tatsuhiro Yamada , Tadakiyo Nakagawa , Yasuhiro Tanaka , Kohichi Fujita , Tomoyuki Tagami , Yuka Ikenoue , Shunsuke Fukuda , Yoshitomo Chujo , Manabu Suzuki , Masahiro Murata
发明人： Tatsuhiro Yamada , Tadakiyo Nakagawa , Yasuhiro Tanaka , Kohichi Fujita , Tomoyuki Tagami , Yuka Ikenoue , Shunsuke Fukuda , Yoshitomo Chujo , Manabu Suzuki , Masahiro Murata
IPC分类号： A61K31/519 , C07D471/04 , C07D471/14 , A61P1/04 , A61P19/02
CPC分类号： C07D471/04 , A61K31/519
摘要： The inventive subject matter relates to compounds, pharmaceutical compositions, and kits containing a heterocyclic compound represented by the formula (I) wherein R is an alkyl group optionally having substituent(s) etc., X is an amino group optionally having substituent(s), Y1 and Y2 are nitrogen atoms etc., an isomer or solvate thereof or a pharmaceutically acceptable salt thereof as an active ingredient.
摘要翻译：本发明涉及包含式（I）表示的杂环化合物的化合物，药物组合物和试剂盒，其中R是任选具有取代基的烷基等。X是任选具有取代基的氨基， Y 1和Y 2是氮原子等，其异构体或溶剂合物或其药学上可接受的盐作为活性成分。

8. 发明授权

US08766900B2 Display apparatus 有权
公开(公告)号：US08766900B2
公开(公告)日：2014-07-01
申请号：US13804946
申请日：2013-03-14
申请人： Yasuhiro Tanaka , Hironobu Isami , Haruhisa Iida , Hidenori Kikuchi , Yukihide Ode
发明人： Yasuhiro Tanaka , Hironobu Isami , Haruhisa Iida , Hidenori Kikuchi , Yukihide Ode
IPC分类号： G09G3/36 , G09G5/00
CPC分类号： G09G5/001 , G09G3/20 , G09G3/3677 , G09G3/3688 , G09G2310/027 , G09G2310/0286 , G09G2310/0289 , G09G2310/061 , G09G2310/08
摘要： There is a need for decreasing a variation in times for writing to TFT elements for pixels in a direction along the extension of a gate line in a liquid crystal display apparatus. A display apparatus includes a display panel having multiple gate lines and drain lines arranged in a matrix and a data driver for outputting a display data signal to each drain line. The data driver includes: an internal control signal generation circuit generating an internal control signal for setting a timing to output a data signal to a drain line of each block on a block basis by dividing the plurality of drain lines into multiple blocks; and a register circuit for recording a setting for division of the block, a setting for delay direction and width of a timing to output the data signal, and a setting for rising and falling of an internal control signal.

9. 发明授权

US08585223B2 Light-shielding coating and optical element 有权
公开(公告)号：US08585223B2
公开(公告)日：2013-11-19
申请号：US12986002
申请日：2011-01-06
申请人： Yasuhiro Tanaka
发明人： Yasuhiro Tanaka
IPC分类号： G02B27/00 , G02B5/02
摘要： The light-shielding coating contains (a) a resin, (b) a coloring material, (c) inorganic fine particles, and (d) a surfactant and/or an oil. The concentration of Component (d), the surfactant and/or the oil, is higher in the uppermost layer of the coating than in the lower layer. The content ratio of Component (d) is in the range of 10 to 40 weight % relative to the total weight of the light-shielding coating. The optical element features this light-shielding coating.

10. 发明授权

US08529075B2 Antireflection structure, optical unit, and optical device 有权
标题翻译：防反射结构，光学单元和光学器件
公开(公告)号：US08529075B2
公开(公告)日：2013-09-10
申请号：US12676083
申请日：2008-09-03
申请人： Kazuhiro Yamada , Takamasa Tamura , Yasuhiro Tanaka
发明人： Kazuhiro Yamada , Takamasa Tamura , Yasuhiro Tanaka
IPC分类号： G02B5/22 , G02B7/02
CPC分类号： G02B1/118 , G02B5/003 , G02B5/045 , G02B7/02
摘要： An antireflection structure having a high antireflection effect is provided.An antireflection structure (50) reduces reflection of light having a wavelength equal to or larger than a predetermined wavelength, and absorbs the light whose reflection is reduced. The antireflection structure (50) includes a base structure portion (7) which is configured to have a plurality of structural units (70) arranged on a reference plane, and each having a tilted surface (71) so that an angle between the first side surface (71) and a reference plane (51) is a predetermined angle, and a plurality of fine concave/convex portions (8, 8, . . . ) which are formed on a surface of the base structure portion (7), and arranged within a cycle equal to or smaller than the predetermined wavelength.
摘要翻译：提供了具有高抗反射效果的抗反射结构。抗反射结构（50）减少了具有等于或大于预定波长的波长的光的反射，并且吸收反射减小的光。防反射结构（50）包括基部结构部（7），该基部构造部（7）被配置为具有布置在基准平面上的多个结构单元（70），并且各自具有倾斜表面（71），使得第一侧表面（71）和参考平面（51）是预定角度，并且形成在基部结构部分（7）的表面上的多个精细凹凸部（8,8 ...）和布置在等于或小于预定波长的周期内。

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