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1. 发明申请

US20060277015A1 Simulation system for functions of biological organs and recording medium in which program therefor is recorded 审中-公开
标题翻译：用于生物器官和记录介质功能的仿真系统，其中记录有程序
公开(公告)号：US20060277015A1
公开(公告)日：2006-12-07
申请号：US11430557
申请日：2006-05-09
申请人： Yasuhiro Kouchi , Takeo Saitou , Masayoshi Seike , Hiromu Nakajima
发明人： Yasuhiro Kouchi , Takeo Saitou , Masayoshi Seike , Hiromu Nakajima
IPC分类号： G06G7/48 , G06G7/58
CPC分类号： G16H50/50
摘要： A simulation system for simulating functions of biological organs, comprising a biological model in which the functions of the biological organs are expressed by mathematical models. The biological model comprises a hepatic metabolism model block having specified input and output relating to hepatic function for simulating the hepatic function. The system further comprises arithmetic means for calculating an output value by using measurable status variables of a liver based on input value to the hepatic metabolism model block.
摘要翻译：一种用于模拟生物器官功能的模拟系统，包括一个生物模型，其中生物器官的功能由数学模型表达。该生物学模型包括肝脏代谢模型块，具有与用于模拟肝功能的肝功能相关的输入和输出。该系统还包括用于基于肝代谢模型块的输入值通过使用肝脏的可测量状态变量来计算输出值的算术装置。

2. 发明申请

US20060265136A1 Treatment effect prediction system, a treatment effect prediction method, and a computer program product thereof 有权
标题翻译：治疗效果预测系统，治疗效果预测方法及其计算机程序产品
公开(公告)号：US20060265136A1
公开(公告)日：2006-11-23
申请号：US11431594
申请日：2006-05-11
申请人： Yasuhiro Kouchi , Takeo Saitou , Masayoshi Seike
发明人： Yasuhiro Kouchi , Takeo Saitou , Masayoshi Seike
IPC分类号： G06F19/00 , G06Q50/00
CPC分类号： G06F19/20 , G06F19/00 , G06F19/34 , G06F19/3481 , G06Q50/24 , G16H50/50 , G16H50/70
摘要： A treatment effect prediction system, comprising: a processor; and a memory, under control of the processor, including instructions enabling the processor to carry out operations comprising: determining a patient pathological condition information, which represents a feature of pathological condition of a patient, based on diagnostic data of the patient; accessing a database of stored pathological condition information and corresponding treatment effects occurring when predetermined treatment is provided; and retrieving, from the database, a specific treatment effect corresponding to the one of the stored pathological condition information that is similar to the patient pathological condition information, is disclosed. A treatment effect prediction method and a computer program product thereof are also disclosed.
摘要翻译：一种治疗效果预测系统，包括：处理器; 以及在所述处理器的控制下的存储器，包括使得所述处理器能够执行操作的指令，所述指令基于所述患者的诊断数据来确定患者病理状况信息，其表示患者病理状态的特征; 访问存储的病理状况信息的数据库和提供预定治疗时发生的相应治疗效果; 并且从数据库中检索与存储的病理状况信息相对应的与患者病理状况信息相似的特定治疗效果。还公开了一种治疗效果预测方法及其计算机程序产品。

3. 发明申请

US20070287144A1 Biological response prediction system, method for predicting biological response and computer program product 审中-公开
标题翻译：生物反应预测系统，预测生物反应方法和计算机程序产品
公开(公告)号：US20070287144A1
公开(公告)日：2007-12-13
申请号：US11805825
申请日：2007-05-24
申请人： Yasuhiro Kouchi , Takeo Saitou , Masayoshi Seike
发明人： Yasuhiro Kouchi , Takeo Saitou , Masayoshi Seike
IPC分类号： G06G7/48 , G06G7/58 , C12Q1/00
CPC分类号： A61B5/14532 , G16H50/50
摘要： A biological response prediction system for predicting the biological response receives the input of the actual measurement data of a subject, and generates virtual biological organ virtually constructed in a computer system using the input actual measurement data, the virtual biological organ corresponding to a function of a biological organ of the subject. The system further acquires the virtual biological response indicated by the virtual biological organ when input is provided to the generated virtual biological organ, and outputs the acquired virtual biological response.
摘要翻译：用于预测生物反应的生物反应预测系统接收对象的实际测量数据的输入，并使用输入的实际测量数据生成虚拟构建在计算机系统中的虚拟生物器官，虚拟生物器官对应于主体的生物器官。该系统进一步获取虚拟生物器官在向所产生的虚拟生物器官提供输入时所指示的虚拟生物学响应，并输出获得的虚拟生物学反应。

4. 发明申请

US20070179771A1 Medical simulation system, computer system and computer program product 审中-公开
标题翻译：医疗仿真系统，计算机系统和计算机程序产品
公开(公告)号：US20070179771A1
公开(公告)日：2007-08-02
申请号：US11698393
申请日：2007-01-26
申请人： Yasuhiro Kouchi , Takeo Saitou , Masayoshi Seike , Takayuki Takahata
发明人： Yasuhiro Kouchi , Takeo Saitou , Masayoshi Seike , Takayuki Takahata
IPC分类号： G06G7/48 , G06G7/58
CPC分类号： G09B23/00
摘要： A medical simulation system has a replacing section for replacing at least a part of a plurality of biological function state values represented by the biological model and a simulating section for generating post-replacement simulated biological response on the basis of the biological model which reflects the replaced value.
摘要翻译：一种医疗模拟系统具有替换部分，用于代替由生物模型表示的多个生物功能状态值的至少一部分，以及用于根据反映替换的生物模型产生替代后模拟生物反应的模拟部分值。

5. 发明申请

US20070118347A1 Medical simulation system and computer program product 审中-公开
标题翻译：医疗仿真系统和计算机程序产品
公开(公告)号：US20070118347A1
公开(公告)日：2007-05-24
申请号：US11602685
申请日：2006-11-21
申请人： Yasuhiro Kouchi , Takeo Saitou , Masayoshi Seike , Takayuki Takahata
发明人： Yasuhiro Kouchi , Takeo Saitou , Masayoshi Seike , Takayuki Takahata
IPC分类号： G06G7/48 , G06G7/58
CPC分类号： G09B23/28
摘要： A medical simulation system includes a biological response inputting section that receives input of biological response information indicating an actual biological response of biological body, a biological model generating section that generates a biological model for reproduction of simulated response simulating the actual biological response, a pathologic condition characteristics acquiring section that acquires pathologic condition characteristics information indicating characteristics of pathologic condition of the biological body based on the generated biological model, and an outputting section that outputs the biological response information and the pathologic condition characteristics information.
摘要翻译：医疗模拟系统包括：生物反应输入部，其接收表示生物体的实际生物反应的生物反应信息的输入;生物模型生成部，其生成模拟实际生物反应的模拟响应的生物体模型;病理状态特征获取部，其基于生成的生物体模型获取表示生物体的病理状态的特征的病理状况特征信息，以及输出部，其输出生物反应信息和病理状况特征信息。

6. 发明授权

US08793144B2 Treatment effect prediction system, a treatment effect prediction method, and a computer program product thereof 有权
标题翻译：治疗效果预测系统，治疗效果预测方法及其计算机程序产品
公开(公告)号：US08793144B2
公开(公告)日：2014-07-29
申请号：US11431594
申请日：2006-05-11
申请人： Yasuhiro Kouchi , Takeo Saitou , Masayoshi Seike
发明人： Yasuhiro Kouchi , Takeo Saitou , Masayoshi Seike
IPC分类号： G06Q50/00 , G06F19/20 , G06F19/00 , G06Q50/24
CPC分类号： G06F19/20 , G06F19/00 , G06F19/34 , G06F19/3481 , G06Q50/24 , G16H50/50 , G16H50/70
摘要： A treatment effect prediction system, comprising: a processor; and a memory, under control of the processor, including instructions enabling the processor to carry out operations comprising: determining a patient pathological condition information, which represents a feature of pathological condition of a patient, based on diagnostic data of the patient; accessing a database of stored pathological condition information and corresponding treatment effects occurring when predetermined treatment is provided; and retrieving, from the database, a specific treatment effect corresponding to the one of the stored pathological condition information that is similar to the patient pathological condition information, is disclosed. A treatment effect prediction method and a computer program product thereof are also disclosed.
摘要翻译：一种治疗效果预测系统，包括：处理器; 以及在所述处理器的控制下的存储器，包括使得所述处理器能够执行操作的指令，所述指令基于所述患者的诊断数据来确定患者病理状况信息，其表示患者病理状态的特征; 访问存储的病理状况信息的数据库和提供预定治疗时发生的相应治疗效果; 并且从数据库中检索与存储的病理状况信息相对应的与患者病理状况信息相似的特定治疗效果。还公开了一种治疗效果预测方法及其计算机程序产品。

7. 发明授权

US08073629B2 Simulation system of function of biological organ 失效
标题翻译：生物器官功能模拟系统
公开(公告)号：US08073629B2
公开(公告)日：2011-12-06
申请号：US11805743
申请日：2007-05-24
申请人： Yasuhiro Kouchi , Takeo Saitou , Masayoshi Seike
发明人： Yasuhiro Kouchi , Takeo Saitou , Masayoshi Seike
IPC分类号： G06F19/00
CPC分类号： G16H50/50 , G06F19/00
摘要： A simulation system for simulating a function of a biological organ using a biological model in which the function of the biological organ are represented by a mathematical model with a computer is provided. The present system receives input of time-series actual measurement data representing the biological response of a subject, estimates the biological response of the subject at a time point at which the measurement is not performed by using the input time-series actual measurement data, and generates time-series reference data representing the biological response of the subject. The present system further generates a virtual biological organ virtually constructed in a computer system using the times-series reference data. The virtual biological organ corresponds to the function of a biological organ of the subject.
摘要翻译：提供了一种使用生物器官功能模拟生物器官的功能的模拟系统，其中生物器官的功能由计算机的数学模型表示。本系统接收表示对象生物学响应的时间序列实际测量数据的输入，通过使用输入的时间序列实际测量数据来估计未进行测量的时间点的对象的生物学响应，以及生成表示对象的生物反应的时间序列参考数据。本系统还使用时间序列参考数据生成虚拟构建在计算机系统中的虚拟生物器官。虚拟生物器官对应于受试者的生物器官的功能。

8. 发明申请

US20090177453A1 Medical diagnosis support computer system, computer program, and server computer 审中-公开
标题翻译：医疗诊断支持计算机系统，计算机程序和服务器计算机
公开(公告)号：US20090177453A1
公开(公告)日：2009-07-09
申请号：US12152593
申请日：2008-05-15
申请人： Yasuhiro Kouchi , Takeo Saitou , Masayoshi Seike
发明人： Yasuhiro Kouchi , Takeo Saitou , Masayoshi Seike
IPC分类号： G06G7/48 , G06F3/048
CPC分类号： G16H50/50
摘要： A medical diagnosis support computer system for supporting diagnosis of a patient by a doctor, the system comprising: a display device; and a controller in communication with the display device, the controller comprising a processor configured to build a biological model representing biological functions of the patient on a computer, generate pathological condition information of the patient based on the biological model, display a doctor screen and a patient screen in a switchable manner on the display device; wherein the doctor screen is configured to simultaneously display a screen region for displaying the pathological condition information of the patient and a screen region for displaying one or more related information related to the patient; and the patient screen is configured to selectively display a display content between the pathological condition information of the patient and one or more related information related to the patient is disclosed.
摘要翻译：一种用于支持医生对患者的诊断的医疗诊断支持计算机系统，所述系统包括：显示装置; 以及与所述显示装置通信的控制器，所述控制器包括处理器，所述处理器被配置为在计算机上构建表示所述患者的生物功能的生物学模型，基于所述生物模型生成患者的病理状况信息，显示医生屏幕和患者屏幕以可切换的方式在显示装置上; 其中所述医生画面被配置为同时显示用于显示患者的病理状况信息的屏幕区域和用于显示与患者相关的一个或多个相关信息的屏幕区域; 并且患者屏幕被配置为选择性地显示患者的病理状况信息和与患者相关的一个或多个相关信息之间的显示内容。

9. 发明申请

US20080288228A1 BIOLOGICAL SIMULATION SYSTEM AND COMPUTER PROGRAM PRODUCT 审中-公开
标题翻译：生物仿真系统和计算机程序产品
公开(公告)号：US20080288228A1
公开(公告)日：2008-11-20
申请号：US12043752
申请日：2008-03-06
申请人： Yasuhiro Kouchi , Takeo Saitou , Masayoshi Seike
发明人： Yasuhiro Kouchi , Takeo Saitou , Masayoshi Seike
IPC分类号： G06F9/455 , G06F7/06 , G06F17/30
CPC分类号： G09B23/30 , G16H50/50
摘要： With an object to seek parameters of a biological model corresponding to individual patents, the present invention provides a biological simulation system comprises an internal parameter set generating section which generates internal parameter sets constituting a biological model, a biological model computing section computing output of a biological model which emulates a biological response of a biological organ based on the generated internal parameter set, and a template database having a plurality of combinations of a reference output value of the biological model and an internal parameter set corresponding to the reference output value, wherein the internal parameter set generating section comprises a database referring means which selects a reference output approximate to an actual biological response from said template database and which selects an internal parameter set corresponding to the selected reference output value.
摘要翻译：本发明提供一种生物模拟系统，其特征在于，具备生成构成生物体模型的内部参数组的内部参数组生成部，生物体模型计算部，模型，其基于所生成的内部参数集模拟生物器官的生物反应;以及模板数据库，其具有生物模型的参考输出值和对应于所述参考输出值的内部参数集合的多个组合，其中，内部参数集生成部分包括数据库参考装置，其从所述模板数据库中选择近似于实际生物反应的参考输出，并且选择与所选择的参考输出值对应的内部参数集。

10. 发明申请

US20070288216A1 Simulation system of function of biological organ 失效
标题翻译：生物器官功能模拟系统
公开(公告)号：US20070288216A1
公开(公告)日：2007-12-13
申请号：US11805743
申请日：2007-05-24
申请人： Yasuhiro Kouchi , Takeo Saitou , Masayoshi Seike
发明人： Yasuhiro Kouchi , Takeo Saitou , Masayoshi Seike
IPC分类号： G06G7/60
CPC分类号： G16H50/50 , G06F19/00
摘要： A simulation system for simulating a function of a biological organ using a biological model in which the function of the biological organ are represented by a mathematical model with a computer is provided. The present system receives input of time-series actual measurement data representing the biological response of a subject, estimates the biological response of the subject at a time point at which the measurement is not performed by using the input time-series actual measurement data, and generates time-series reference data representing the biological response of the subject. The present system further generates a virtual biological organ virtually constructed in a computer system using the times-series reference data. The virtual biological organ corresponds to the function of a biological organ of the subject.
摘要翻译：提供了一种使用生物器官功能模拟生物器官的功能的模拟系统，其中生物器官的功能由计算机的数学模型表示。本系统接收表示对象生物学响应的时间序列实际测量数据的输入，通过使用输入的时间序列实际测量数据来估计未进行测量的时间点的对象的生物学响应，以及生成表示对象的生物反应的时间序列参考数据。本系统还使用时间序列参考数据生成虚拟构建在计算机系统中的虚拟生物器官。虚拟生物器官对应于受试者的生物器官的功能。

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