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1. 发明申请

US20120190621A1 CORNEAL ENDOTHELIAL CELL PROLIFERATION PROMOTER 有权
标题翻译：角膜内皮细胞增殖促进剂
公开(公告)号：US20120190621A1
公开(公告)日：2012-07-26
申请号：US13386844
申请日：2009-07-24
申请人： Yasuhiko Tabata , Shigeru Kinoshita , Noriko Koizumi , Yuji Sakamoto , Naoki Okumura , Hiroaki Takahashi
发明人： Yasuhiko Tabata , Shigeru Kinoshita , Noriko Koizumi , Yuji Sakamoto , Naoki Okumura , Hiroaki Takahashi
IPC分类号： A61K38/18 , A61P27/02
CPC分类号： A61K38/1825 , A61K9/0048 , A61K9/06 , A61K47/42
摘要： The present invention aims to provide a corneal endothelium cell proliferation accelerator and a therapeutic agent for a disease relating to corneal endothelium damage, which are administered into the anterior chamber. bFGF is released in a sustained manner by forming bFGF sustained-release gelatin hydrogel particles wherein bFGF is carried on gelatin hydrogel. Therefore, the proliferation of corneal endothelium cells can be accelerated persistently by administration of a preparation containing the bFGF sustained-release gelatin hydrogel particles into the anterior chamber, and diseases relating to corneal endothelium damage can be treated.
摘要翻译：本发明的目的在于提供角膜内皮细胞增殖促进剂和与角膜内皮损伤相关的疾病的治疗剂，其被施用于前房。通过形成bFGF缓释明胶水凝胶颗粒，其中bFGF携带在明胶水凝胶上，以持续的方式释放bFGF。因此，可以通过将含有bFGF缓释明胶水凝胶颗粒的制剂给予前房来持续加速角膜内皮细胞的增殖，并且可以治疗与角膜内皮损伤有关的疾病。

2. 发明授权

US08895508B2 Methods for corneal endothelial proliferation using bFGF sustained-release gelatin hydrogel particles 有权
标题翻译：使用bFGF缓释明胶水凝胶颗粒进行角膜内皮增殖的方法
公开(公告)号：US08895508B2
公开(公告)日：2014-11-25
申请号：US13386844
申请日：2009-07-24
申请人： Yasuhiko Tabata , Shigeru Kinoshita , Noriko Koizumi , Yuji Sakamoto , Naoki Okumura , Hiroaki Takahashi
发明人： Yasuhiko Tabata , Shigeru Kinoshita , Noriko Koizumi , Yuji Sakamoto , Naoki Okumura , Hiroaki Takahashi
IPC分类号： A61K38/18 , A61K9/00 , A61K9/06 , A61K47/42
CPC分类号： A61K38/1825 , A61K9/0048 , A61K9/06 , A61K47/42
摘要： The present invention aims to provide a corneal endothelium cell proliferation accelerator and a therapeutic agent for a disease relating to corneal endothelium damage, which are administered into the anterior chamber. bFGF is released in a sustained manner by forming bFGF sustained-release gelatin hydrogel particles wherein bFGF is carried on gelatin hydrogel. Therefore, the proliferation of corneal endothelium cells can be accelerated persistently by administration of a preparation containing the bFGF sustained-release gelatin hydrogel particles into the anterior chamber, and diseases relating to corneal endothelium damage can be treated.
摘要翻译：本发明的目的在于提供角膜内皮细胞增殖促进剂和与角膜内皮损伤相关的疾病的治疗剂，其被施用于前房。通过形成bFGF缓释明胶水凝胶颗粒，其中bFGF携带在明胶水凝胶上，以持续的方式释放bFGF。因此，可以通过将含有bFGF缓释明胶水凝胶颗粒的制剂给予前房来持续加速角膜内皮细胞的增殖，并且可以治疗与角膜内皮损伤有关的疾病。

3. 发明授权

US07482900B2 Micro relay 失效
标题翻译：微型继电器
公开(公告)号：US07482900B2
公开(公告)日：2009-01-27
申请号：US10556349
申请日：2005-01-25
申请人： Takeshi Hashimoto , Noriteru Furumoto , Naoki Okumura , Hideki Enomoto , Takeshi Sadamori , Shinichi Kishimoto , Tsutomu Shimomura , Kouji Sakai , Masami Hori
发明人： Takeshi Hashimoto , Noriteru Furumoto , Naoki Okumura , Hideki Enomoto , Takeshi Sadamori , Shinichi Kishimoto , Tsutomu Shimomura , Kouji Sakai , Masami Hori
IPC分类号： H01H67/02
CPC分类号： H01H50/005 , H01H2050/007
摘要： The micro relay of the present invention comprises a base substrate 3, an armature block 5, and a cover 7. The base substrate 3 has a storage recess 41 for accommodating an electromagnetic device 1. The storage recess is composed of a hole 41a penetrating the base substrate 3 and a thin storage recess lid fixed on the one surface of the base substrate to close the hole. The electromagnetic device 1 is isolated from a contact mechanism by the storage recess lid 41b to increase the reliability of the contacts. The electromagnetic device 1 includes a yoke 10, a coil 11 wound around the yoke to generate a flux in response to an exciting current, and a permanent magnet 12 secured to the yoke to generate a flux flowing through an armature 51 and the yoke 10. Because the permanent magnet 12 is secured to the yoke 10, this micro relay can reduce the thickness.
摘要翻译：本发明的微型继电器包括基底基板3，电枢块5和盖7.基底基板3具有用于容纳电磁装置1的储存凹部41.储存凹部由贯穿基底基板3和固定在基底基板的一个表面上的薄的储存凹部盖以封闭孔。电磁装置1通过存储凹部盖41b与接触机构隔离，以提高触点的可靠性。电磁装置1包括磁轭10，卷绕在磁轭上以产生响应于励磁电流的磁通的线圈11和固定到磁轭的永磁体12，以产生流过电枢51和磁轭10的磁通。因为永磁体12被固定到磁轭10上，所以这个微型继电器可以减小厚度。

4. 发明申请

US20060250201A1 Micro relay 失效
标题翻译：微型继电器
公开(公告)号：US20060250201A1
公开(公告)日：2006-11-09
申请号：US10556349
申请日：2005-01-25
申请人： Takeshi Hashimoto , Noriteru Furumoto , Naoki Okumura , Hideki Enomoto , Takeshi Sadamori , Shinichi Kishimoto , Tsutomu Shimomura , Kouji Sakai , Masami Hori
发明人： Takeshi Hashimoto , Noriteru Furumoto , Naoki Okumura , Hideki Enomoto , Takeshi Sadamori , Shinichi Kishimoto , Tsutomu Shimomura , Kouji Sakai , Masami Hori
IPC分类号： H01H51/22
CPC分类号： H01H50/005 , H01H2050/007
摘要： The micro relay of the present invention comprises a base substrate 3, an armature block 5, and a cover 7. The base substrate 3 has a storage recess 41 for accommodating an electromagnetic device 1. The storage recess is composed of a hole 41a penetrating the base substrate 3 and a thin storage recess lid fixed on the one surface of the base substrate to close the hole. The electromagnetic device 1 is isolated from a contact mechanism by the storage recess lid 41b to increase the reliability of the contacts. The electromagnetic device 1 includes a yoke 10, a coil 11 wound around the yoke to generate a flux in response to an exciting current, and a permanent magnet 12 secured to the yoke to generate a flux flowing through an armature 51 and the yoke 10. Because the permanent magnet 12 is secured to the yoke 10, this micro relay can reduce the thickness.
摘要翻译：本发明的微型继电器包括基底基板3，电枢块5和盖7.基底基底3具有用于容纳电磁装置1的储存凹部41.储存凹部由孔41穿透基底基板3和固定在基底基板的一个表面上的薄的储存凹部盖以封闭孔。电磁装置1通过存储凹部盖41b与接触机构隔离，以提高触点的可靠性。电磁装置1包括磁轭10，卷绕在磁轭上以产生响应于励磁电流的磁通的线圈11和固定到磁轭的永磁体12，以产生流过电枢51和磁轭10的磁通。因为永磁体12被固定到磁轭10上，所以这个微型继电器可以减小厚度。

5. 发明授权

US07102473B2 Micro-relay 失效
标题翻译：微型继电器
公开(公告)号：US07102473B2
公开(公告)日：2006-09-05
申请号：US10492642
申请日：2003-07-31
申请人： Kouji Sakai , Hideki Enomoto , Naoki Okumura , Tsutomu Shimomura , Masami Hori
发明人： Kouji Sakai , Hideki Enomoto , Naoki Okumura , Tsutomu Shimomura , Masami Hori
IPC分类号： H01H62/07
CPC分类号： H01H50/005 , H01H50/023 , H01H50/026 , H01H2050/007
摘要： This micro relay comprises a body 1, a cover 4, an armature block 3. The body 1, which is made of silicon or glass, has an electromagnetic mechanism 2. The cover 4 is also made of silicon or glass. The armature block 3 is made of silicon. The armature block 3 is composed of an armature base 30 and a frame 31. The frame 31 surrounds an entire circumference of the armature base 30 and supports the armature base 30 pivotally. The armature base 30 is cooperative with a magnetic material 32 on a surface of the armature base 30 to define an armature 300. A fixed contacts 14A, 14B, 15A, 15B and movable contacts 33A, 33B are selectively closed and opened by a pivot motion of the armature 300. And, the frame 31 is directly bonded over its entire circumference to a periphery 19 of the body 1 and to a periphery 41 of the cover 4 to define a sealed space surrounded by the frame 31 and closed between the body 1 and the cover 4 for accommodating the armature 300 and the fixed contacts and the movable contacts.
摘要翻译：该微型继电器包括主体1，盖4，电枢块3。由硅或玻璃制成的主体1具有电磁机构2。盖4也由硅或玻璃制成。电枢块3由硅制成。电枢块3由电枢基座30和框架31构成。框架31围绕电枢基座30的整个圆周并且枢转地支撑电枢基座30。电枢基座30与电枢基座30的表面上的磁性材料32配合，以限定电枢300。固定触头14A，14B，15A，15B和可动触点33A，33B通过电枢300的枢转运动选择性地闭合和打开。并且，框架31在其整个圆周上直接接合到主体1的周边19和盖4的周边41，以限定由框架31包围并在主体1和盖4之间封闭的密封空间，用于容纳电枢300和固定触点和可动触头。

6. 发明授权

US4119442A Process for manufacturing a steel product 失效
标题翻译：钢材制造工艺
公开(公告)号：US4119442A
公开(公告)日：1978-10-10
申请号：US746307
申请日：1976-12-01
申请人： Michihiko Nagumo , Tohru Inoue , Naoki Okumura
发明人： Michihiko Nagumo , Tohru Inoue , Naoki Okumura
IPC分类号： B21B1/02 , C21D7/13
CPC分类号： C21D7/13 , B21B1/026
摘要： A process for making a steel product so that the ratio of the initial thickness (D) of the cast slab to the final thickness (d) of the rolled product is between 2 to 6. The product has excellent mechanical properties.
摘要翻译：制造钢制品的方法，使得铸坯的初始厚度（D）与轧制产品的最终厚度（d）之比在2至6之间。该产品具有优异的机械性能。

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