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1. 发明授权

US09283327B2 Auto-injector 有权
标题翻译：自动进样器
公开(公告)号：US09283327B2
公开(公告)日：2016-03-15
申请号：US13993531
申请日：2011-12-21
申请人： Yannick Hourmand , Timothy Donald Barrow-Williams , Matthew Ekman
发明人： Yannick Hourmand , Timothy Donald Barrow-Williams , Matthew Ekman
IPC分类号： A61M5/32 , A61M5/20
CPC分类号： A61M5/3245 , A61M5/2033 , A61M5/326 , A61M2005/206 , A61M2005/208
摘要： According to the invention, an auto-injector for administering a dose of a liquid medicament (M) comprises of a substantially cylindrical housing arranged to contain a pre-filled syringe; a syringe retainer slidably arranged with respect to the housing that mounts a pre-filled syringe with an injection needle, a plunger and a stopper for sealing a syringe barrel of the pre-filled syringe; a coupling shroud slidably arranged within the housing and releasably coupled to the plunger; and a single drive means. Upon release, the single drive means is capable of driving the coupling shroud in the proximal direction (P). The proximal translatory movement of the coupling shroud with respect to the housing, translates the syringe retainer in the proximal direction (P) to expose the injection needle of the pre-filled syringe, depresses the plunger connected to the stopper into the syringe barrel to expel the dose of medicament (M) and advances a needle shroud to a safe position (PS) to surround the injection needle after the medicament (M) has been at least partially delivered. The coupling shroud is decoupled from the plunger at a pre-determined second position (II) defined by an aperture formed into the housing.
摘要翻译：根据本发明，用于给药液体药物（M）的自动注射器包括布置成容纳预填充注射器的基本上圆柱形的壳体; 相对于所述壳体可滑动地布置的注射器保持器，其用注射针，柱塞和用于密封所述预先填充的注射器的注射器筒的止动器安装预填充的注射器; 联接罩，其可滑动地布置在所述壳体内并且可释放地联接到所述柱塞; 和单个驱动装置。在释放时，单个驱动装置能够沿近端方向（P）驱动联接罩。耦合护罩相对于壳体的近侧平移运动使注射器保持器沿近端方向（P）平移以暴露预填充注射器的注射针，将连接到塞子的柱塞压入注射器筒以排出药剂（M）的剂量并且在药物（M）已经被至少部分递送之后，将针罩延伸到安全位置（PS）以包围注射针。耦合罩在由形成在壳体中的孔限定的预定的第二位置（II）处与柱塞分离。

2. 发明授权

US08911410B2 Auto-injector 有权
标题翻译：自动进样器
公开(公告)号：US08911410B2
公开(公告)日：2014-12-16
申请号：US13579450
申请日：2011-02-16
申请人： Matthew Ekman , Timothy Donald Barrow-Williams , Yannick Hourmand
发明人： Matthew Ekman , Timothy Donald Barrow-Williams , Yannick Hourmand
IPC分类号： A61M5/32 , A61M37/00 , A61M5/20
CPC分类号： A61M5/3221 , A61M5/2033 , A61M5/3204 , A61M5/326 , A61M2005/206 , A61M2005/2073
摘要： The invention relates to an auto-injector (1) with a delay mechanism (36) for slowing down motion of a retraction sleeve (10) in axial direction of the auto-injector (1), the delay mechanism (36) comprising a circumferential outer wall (37) with a back collar (38) attached to a housing (2) of the auto-injector (1) and a circumferential inner wall (39) with a front collar (40) attached to the retraction sleeve (10) wherein a cavity is defined between the outer wall (37) and inner wall (39), the cavity sealed by the back collar (38) against the inner wall (39) and by the front collar (40) against the outer wall (37), the cavity filled with a viscous fluid, wherein at least one orifice is arranged in the delay mechanism (36) for allowing the viscous fluid to be pushed out as the volume of the cavity decreases due to axial motion of the component with respect to the housing. The retraction sleeve (10) is axially movably arranged in the housing (2) and serves for retracting the syringe (3) with the needle (4) into the covered position after delivering the medicament (M).
摘要翻译：本发明涉及一种具有延迟机构（36）的自动注射器（1），用于在自动注射器（1）的轴向方向上减慢收缩套筒（10）的运动，延迟机构（36）包括周向外壁（37），其具有附接到自动注射器（1）的壳体（2）的后环（38）和具有附接到缩回套筒（10）的前轴环（40）的周向内壁（39）其中在所述外壁（37）和所述内壁（39）之间限定空腔，所述空腔被所述后环（38）密封抵靠所述内壁（39），并且所述前轴环（40）抵靠所述外壁（37）），所述空腔填充有粘性流体，其中在所述延迟机构（36）中布置有至少一个孔口，用于当所述部件的轴向运动相对于所述腔体的轴向运动减小时，允许粘性流体被推出住房。缩回套筒（10）可轴向移动地布置在壳体（2）中，用于在输送药物（M）之后将注射器（3）用针（4）缩回到覆盖位置。

3. 发明授权

US09474866B2 Auto-injector 有权
标题翻译：自动进样器
公开(公告)号：US09474866B2
公开(公告)日：2016-10-25
申请号：US13996145
申请日：2011-12-21
申请人： Yannick Hourmand , Simon Francis Brereton , Thomas Mark Kemp , Rosie Burnell , Matthew Ekman
发明人： Yannick Hourmand , Simon Francis Brereton , Thomas Mark Kemp , Rosie Burnell , Matthew Ekman
IPC分类号： A61M5/32 , A61M5/20 , A61M5/24 , A61M5/46
CPC分类号： A61M5/326 , A61M5/2033 , A61M5/24 , A61M5/46 , A61M2005/206 , A61M2005/208 , A61M2205/581 , A61M2205/582
摘要： The invention refers to an auto-injector for delivering a liquid medicament, comprising: an elongate housing arranged to contain a syringe with a hollow injection needle and a stopper, wherein the syringe is slidably arranged with respect to the housing, spring means capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position for insertion into the injection site, operating the syringe to inject the dose of medicament, and advancing a needle shroud over the needle for providing needle safety, activating means arranged to lock and release the spring means, wherein the spring means is a single drive spring in the shape of a compression spring grounded distally in the housing and proximally bearing against a thrust collar arranged to transmit load from the spring means via a plunger to the syringe and/or the stopper for needle insertion and injection, wherein the plunger is engageable to the thrust collar for joint axial translation, wherein the plunger is disengageable from the thrust collar on relative rotation so as to allow the thrust collar to be advanced further by the drive spring in order to engage the needle shroud for advancing it over the needle.

4. 发明授权

US09352089B2 Auto-injector 有权
标题翻译：自动进样器
公开(公告)号：US09352089B2
公开(公告)日：2016-05-31
申请号：US13807140
申请日：2011-06-27
申请人： Yannick Hourmand , Timothy Donald Barrow-Williams , Matthew Ekman
发明人： Yannick Hourmand , Timothy Donald Barrow-Williams , Matthew Ekman
IPC分类号： A61M5/20 , A61M5/315 , A61M5/32 , A61M5/46
CPC分类号： A61M5/2033 , A61M5/31511 , A61M5/326 , A61M5/46 , A61M2005/206 , A61M2005/208
摘要： An auto-injector comprising a housing arranged to contain a syringe. The syringe is slidably arranged with respect to the housing, a spring capable of pushing a needle from a covered position into an advanced position, operating the syringe to supply a dose of medicament, and retracting the syringe into a covered position and an activator. The spring is arranged to be grounded in the housing for advancing the needle and for injecting the dose of medicament. The drive spring grounded in the housing switched to its proximal end for retracting the syringe. An interlock sleeve telescoped within the housing. The activator comprises a trigger, wherein the trigger button is locked, thereby preventing actuation when the interlock sleeve is in its proximal position in an as delivered state and wherein translation of the interlock sleeve unlocks the trigger button so as to allow actuation.
摘要翻译：一种自动注射器，包括布置成容纳注射器的壳体。注射器相对于壳体可滑动地布置，弹簧能够将针从覆盖位置推入前进位置，操作注射器以供应一定剂量的药物，并将注射器缩回到覆盖位置和活化剂。弹簧布置成在壳体中接地以推进针头并注射剂量的药物。接地在壳体中的驱动弹簧切换到其近端以缩回注射器。在壳体内伸缩的互锁套筒。激活器包括触发器，其中触发器按钮被锁定，从而当互锁套筒处于处于其传送状态的近端位置时防止致动，并且其中互锁套筒的平移解除触发按钮以允许致动。

5. 发明申请

US20130317446A1 Auto-Injector 有权
标题翻译：自动进样器
公开(公告)号：US20130317446A1
公开(公告)日：2013-11-28
申请号：US13807140
申请日：2011-06-27
申请人： Yannick Hourmand , Timothy Donald Barrow-Williams , Matthew Ekman
发明人： Yannick Hourmand , Timothy Donald Barrow-Williams , Matthew Ekman
IPC分类号： A61M5/20
CPC分类号： A61M5/2033 , A61M5/31511 , A61M5/326 , A61M5/46 , A61M2005/206 , A61M2005/208
摘要： The invention relates to an auto-injector for administering a dose of a liquid medicament, comprising: an elongate housing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, wherein the syringe is slidably arranged with respect to the housing, spring means capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end, operating the syringe to supply the dose of medicament, and retracting the syringe with the needle into the covered position after delivering the medicament, activating means. The spring means is a single drive spring arranged to be grounded at a distal end in the housing for advancing the needle and for injecting the dose of medicament via a plunger. The drive spring has its ground in the housing switched to its proximal end for retracting the syringe. An interlock sleeve is telescoped in the proximal end of the housing. The activating means comprises a trigger button arranged at the distal end of the auto-injector, wherein the trigger button is locked, thereby preventing actuation when the interlock sleeve is in its proximal position in an as delivered state and wherein translation of the interlock sleeve unlocks the trigger button so as to allow actuation.
摘要翻译：本发明涉及一种用于给药液体药物的自动注射器，其包括：细长壳体，布置成容纳具有中空针头的注射器和用于密封注射器和移位药剂的塞子，其中注射器可滑动地布置有相对于壳体，弹簧装置能够在启动时：将针从壳体内的覆盖位置推入通过孔口的前进位置并经过近端，操作注射器以供应剂量的药物，并且缩回注射器在输送药物，激活装置之后，针头进入覆盖位置。弹簧装置是单个驱动弹簧，其布置成在壳体中的远端处接地，用于推进针头并且用于经由柱塞喷射剂量的药剂。驱动弹簧在壳体中的地面切换到其近端以缩回注射器。联锁套筒可伸缩在壳体的近端。激活装置包括布置在自动注射器的远端处的触发按钮，其中触发按钮被锁定，从而当互锁套筒处于其接近位置处于交付状态时防止致动，并且互锁套筒的平移解锁触发按钮以允许致动。

6. 发明申请

US20130123710A1 Auto-Injector with a Torsion Spring 有权
标题翻译：带扭转弹簧的自动进样器
公开(公告)号：US20130123710A1
公开(公告)日：2013-05-16
申请号：US13579455
申请日：2011-02-16
申请人： Matthew Ekman , Timothy Donald Barrow-Williams , Yannick Hourmand
发明人： Matthew Ekman , Timothy Donald Barrow-Williams , Yannick Hourmand
IPC分类号： A61M5/32
CPC分类号： A61M5/3257 , A61M5/2033 , A61M5/3157 , A61M5/31583 , A61M5/326 , A61M2005/206 , A61M2005/208 , A61M2205/581
摘要： The invention relates to an auto-injector for administering a dose of a liquid medicament (M), comprising: an elongate housing arranged to contain a syringe with a hollow needle and a bung for sealing the syringe and displacing the medicament (M), the elongate housing having a distal end (D) and a proximal end (P) with an orifice intended to be applied against an injection site, wherein the syringe is slidably arranged with respect to the housing, spring means capable of, upon activation, pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end (P) as well as operating the syringe to supply the dose of medicament (M), activating means arranged to lock the spring means in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring means for injection. The spring means is a torsion spring grounded at one end in the housing and at the other end in a first gear member rotatable about a longitudinal axis but axially fixed wherein the first gear member, upon rotation, is arranged for translatively moving a second gear member, the second gear member prevented from rotating and coupled to the bung in order to push it towards the proximal end (P), wherein the first gear member is engaged with the activating means prior to manual operation in a manner to prevent rotation and disengaged from the activating means upon manual operation.
摘要翻译：本发明涉及一种用于给药液体药物（M）的自动注射器，其包括：细长壳体，布置成容纳具有中空针头的注射器和用于密封注射器并移位药剂（M）的栓塞，具有远端（D）和近端（P）的细长壳体，其具有旨在施加在注射部位上的孔口，其中所述注射器相对于所述壳体可滑动地布置，弹簧装置能够在启动时推动针从壳体内的覆盖位置移动到通过孔口并通过近端（P）的前进位置，并且操作注射器以供应剂量的药物（M），启动装置被布置成将弹簧装置锁定在加压在手动操作之前的状态，并且能够在手动操作时释放用于注射的弹簧装置。弹簧装置是扭转弹簧，其一端接合在壳体中，另一端处于第一齿轮构件中，该第一齿轮构件围绕纵向轴线可旋转但是轴向固定，其中第一齿轮构件在旋转时被布置成平移地移动第二齿轮构件，第二齿轮构件被阻止旋转并联接到栓，以将其推向近端（P），其中第一齿轮构件在手动操作之前与致动装置接合以防止旋转和脱离手动操作时的激活装置。

7. 发明申请

US20130123697A1 Auto-Injector With A Torsion Spring 有权
标题翻译：自动进样器带扭转弹簧
公开(公告)号：US20130123697A1
公开(公告)日：2013-05-16
申请号：US13579928
申请日：2011-02-16
申请人： Matthew Ekman , Timothy Donald Barrow-Williams , Yannick Hourmand
发明人： Matthew Ekman , Timothy Donald Barrow-Williams , Yannick Hourmand
IPC分类号： A61M5/32 , A61M5/20
CPC分类号： A61M5/3232 , A61M5/2033 , A61M5/31583 , A61M5/3202 , A61M5/326 , A61M2005/206 , A61M2005/2073 , A61M2005/3152 , A61M2005/325
摘要： The invention relates to an auto-injector for administering a dose of a liquid medicament (M), comprising: an elongate outer casing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament (M), the outer casing having a distal end (D) and a proximal end (P) with an orifice intended to be applied against an injection site, wherein the syringe is slidably arranged with respect to the outer casing, spring means capable of, upon activation: pushing the needle past the proximal end (P), operating the syringe to supply the dose of medicament (M), and retracting the syringe with the needle activating means arranged to lock the spring means in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring means for injection, wherein the spring means is a torsion spring grounded at one end in the outer casing and at the other end in a first gear member rotatable about a longitudinal axis, wherein the first gear member, upon rotation, is arranged for translatively moving a second gear member toward the proximal end (P), the second gear member prevented from rotating and coupled to the stopper in order to push it towards the proximal end (P), wherein the first gear member is engaged with the activating means prior to manual operation in a manner to prevent rotation and disengaged from the activating means upon manual operation.
摘要翻译：本发明涉及一种用于施用剂量的液体药物（M）的自动注射器，包括：细长外壳，布置成容纳具有中空针的注射器和用于密封注射器和移位药剂（M）的止动件，所述外壳具有远端（D）和近端（P），所述近端具有旨在施加在注射部位上的孔，其中所述注射器相对于所述外壳可滑动地布置，所述弹簧装置能够在启动时：将针推过近端（P），操作注射器以供给剂量的药剂（M），并且用针启动装置缩回注射器，该针启动装置被布置成在手动操作之前将弹簧装置锁定在加压状态，并且能够在手动操作时释放用于注射的弹簧装置，其中弹簧装置是在外壳的一端接地的扭力弹簧，另一端处于可围绕纵向轴线旋转的第一齿轮构件，w 这里，第一齿轮构件在旋转时被布置用于朝向近端（P）平移地移动第二齿轮构件，防止第二齿轮构件旋转并联接到止动件，以将其推向近端（P）其中，在手动操作之前，第一齿轮构件与激活装置接合，以防止在手动操作时旋转和从激活装置脱离的方式。

8. 发明授权

US09724472B2 Auto-injector 有权
公开(公告)号：US09724472B2
公开(公告)日：2017-08-08
申请号：US13993528
申请日：2011-12-21
申请人： Yannick Hourmand , Timothy Donald Barrow-Williams , Matthew Ekman
发明人： Yannick Hourmand , Timothy Donald Barrow-Williams , Matthew Ekman
IPC分类号： A61M5/00 , A61M5/20 , A61M5/50 , A61M5/32
CPC分类号： A61M5/2033 , A61M5/326 , A61M5/50 , A61M2005/206 , A61M2005/208
摘要： According to the invention, an auto-injector for administering a dose of a liquid medicament (M) comprises of a substantially cylindrical housing arranged to contain a pre-filled syringe filled with the medicament (M), a needle shroud slibably arranged with respect to the housing and adapted to rest on the skin of a patient receiving an injection, a releasable drive means arranged within the housing that is capable of, upon release, translating the needle shroud in a proximal direction (P) towards a safe position (PS) and a rotating collar rotatably arranged within the housing. The needle shroud in the safe position (PS) surrounds the injection needle after the injection has been carried out. The rotating collar engages the needle shroud in a manner that forces the rotating collar to rotate within the housing when the needle shroud is translated in the proximal direction (P).

9. 发明授权

US09572937B2 Autoinjector having piston rod with non-circular axial bore slidably arranged on housing shaft to prevent relative rotation 有权
标题翻译：自动注射器具有活动杆，其具有非圆形轴向孔，可滑动地布置在壳体轴上以防止相对旋转
公开(公告)号：US09572937B2
公开(公告)日：2017-02-21
申请号：US13579339
申请日：2011-02-16
申请人： Matthew Ekman , Timothy Donald Barrow-Williams , Yannick Hourmand
发明人： Matthew Ekman , Timothy Donald Barrow-Williams , Yannick Hourmand
IPC分类号： A61M5/20 , A61M5/32 , A61M5/46
CPC分类号： A61M5/20 , A61M5/326 , A61M5/46 , A61M2005/206 , A61M2005/208 , A61M2005/3247 , A61M2205/581
摘要： The invention relates to a clutch mechanism for the transmission of a rotary movement from a gear arrangement comprising a first gear member and a second gear member. The first gear member is rotatable about a longitudinal axis but axially fixed wherein the first gear member, upon rotation, is arranged for translatively moving a second gear member which is prevented from rotating. The clutch mechanism comprises a circumferential shoulder arranged at the second gear member and at least one or a number of resilient clutch fingers with respective inclined inner surfaces arranged at the first gear member, the shoulder arranged for increasingly pressing against the inclined surfaces thereby flexing the clutch fingers outward when the shoulder reaches the clutch fingers in the course of its translation. The clutch mechanism further comprises tube arranged around the clutch fingers, the tube having a number of internal longitudinal splines for engaging the flexed-out clutch fingers.
摘要翻译：本发明涉及一种用于从包括第一齿轮构件和第二齿轮构件的齿轮装置传递旋转运动的离合器机构。第一齿轮构件可围绕纵向轴线旋转但是轴向固定，其中第一齿轮构件在旋转时被布置成平移地移动阻止旋转的第二齿轮构件。离合器机构包括布置在第二齿轮构件处的周向肩部和至少一个或多个弹性离合器指状物，其具有布置在第一齿轮构件处的相应的倾斜内表面，肩部设置成越来越多地压靠倾斜表面，从而使离合器当肩膀在其翻译过程中到达离合器手指时，手指向外。离合器机构还包括围绕离合器指状物布置的管，管具有用于接合弯曲离合器指的多个内部纵向花键。

10. 发明授权

US09248245B2 Auto-injector 有权
标题翻译：自动进样器
公开(公告)号：US09248245B2
公开(公告)日：2016-02-02
申请号：US13579435
申请日：2011-02-16
申请人： Matthew Ekman , Timothy Donald Barrow-Williams , Yannick Hourmand
发明人： Matthew Ekman , Timothy Donald Barrow-Williams , Yannick Hourmand
IPC分类号： A61M5/32 , A61M5/20
CPC分类号： A61M5/2033 , A61M5/3204 , A61M5/3232 , A61M5/326 , A61M2005/206 , A61M2005/2073
摘要： An auto-injector for administering a dose of a liquid medicament comprising an elongate housing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, the housing having a distal end and a proximal end with an orifice intended to be applied against an injection site. The syringe is slidably arranged with respect to the housing. A spring capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end (P), operating the syringe to supply the dose of medicament (M), and retracing the syringe with the needle into the covered position. After delivering the medicament, an activator arranged to lock the spring in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring for injection.
摘要翻译：一种用于给药剂量的自动注射器，所述自动注射器包括细长壳体，所述细长壳体布置成容纳具有中空针头的注射器和用于密封所述注射器并使所述药剂移位的止动件，所述壳体具有远端和近端，旨在应用于注射部位。注射器相对于壳体可滑动地布置。一种弹簧，其能够在激活时将所述针从所述壳体内的覆盖位置推入所述孔的前进位置并经过所述近端（P），操作所述注射器以供应所述剂量的药物（M），并且使所述针注射器与针头进入覆盖位置。在输送药物之后，激活器被设置成在手动操作之前将弹簧锁定在加压状态，并且能够在手动操作时释放用于注射的弹簧。

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