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1. 发明授权

US09155844B2 Injection device 有权
标题翻译：注射装置
公开(公告)号：US09155844B2
公开(公告)日：2015-10-13
申请号：US14000113
申请日：2012-02-16
申请人： Simon Francis Brereton , Thomas Kemp , Rosie Burnell , Matthew Ekman
发明人： Simon Francis Brereton , Thomas Kemp , Rosie Burnell , Matthew Ekman
IPC分类号： A61M5/315 , A61M5/20 , A61M5/50 , A61M5/32 , A61M5/46
CPC分类号： A61M5/3157 , A61M5/2033 , A61M5/31501 , A61M5/31536 , A61M5/3202 , A61M5/3204 , A61M5/3257 , A61M5/326 , A61M5/46 , A61M5/5086 , A61M2005/206 , A61M2005/208 , A61M2005/3247 , A61M2205/581 , A61M2205/582
摘要： An injection device for administering a dose of a liquid medicament is disclosed. The device includes a syringe containing the dose and a hollow injection needle. The device includes a stopper translatably disposed within the syringe and a plunger connectable to the stopper and translatable in at least a proximal direction to displace the stopper. The device further includes a releasable noise component capable of, upon release, generating an audible and/or tactile feedback. Proximal displacement of the stopper causes the dose to be expelled through the injection needle. The noise component is released when the plunger reaches a position relative to the syringe in which the stopper is located in proximity of a proximal end of the syringe. The released noise component impacts on at least one component of the injection device to generate the audible and/or tactile feedback indicating the end of the injection.
摘要翻译：公开了一种用于施用剂量的液体药物的注射装置。该装置包括含有剂量的注射器和中空注射针。该装置包括可移动地设置在注射器内的止动件和可连接到止动件的柱塞，并可在至少近端方向上平移以移位塞子。该装置还包括能够在释放时产生可听和/或触觉反馈的可释放噪声分量。塞子的近端位移导致剂量通过注射针排出。当柱塞到达注射器的位置时，噪音分量被释放，止动器位于注射器的近端附近。释放的噪声分量影响注射装置的至少一个部件以产生表示注射结束的声音和/或触觉反馈。

2. 发明申请

US20130317430A1 AUTO-INJECTOR 有权
标题翻译：自动注射器
公开(公告)号：US20130317430A1
公开(公告)日：2013-11-28
申请号：US13983809
申请日：2012-02-16
申请人： Simon Francis Brereton , Thomas Kemp , Rosie Burnell , Matthew Ekman
发明人： Simon Francis Brereton , Thomas Kemp , Rosie Burnell , Matthew Ekman
IPC分类号： A61M5/46
CPC分类号： A61M5/46 , A61M5/20 , A61M5/2033 , A61M5/3157 , A61M5/326 , A61M2005/206 , A61M2205/581 , A61M2205/582
摘要： An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.
摘要翻译：存在用于施用剂量的液体药物（M）的自动注射器，其具有可套叠在管状壳体中的管状底座，载体子组件，其包括相对于壳体内的底盘可滑动地布置的管状载体，其中载体适于包含一个带有中空注射针的注射器。喷射器还具有驱动弹簧和用于将驱动弹簧的负载传递到注射器的止动件的柱塞，其中注射器可锁定以用于与载体的关节轴向平移。控制弹簧布置在载体周围，用于在近端方向（P）上平移载体，用于将针穿过底架插入注射部位。

3. 发明授权

US09789255B2 Auto-injector 有权
公开(公告)号：US09789255B2
公开(公告)日：2017-10-17
申请号：US13983810
申请日：2012-02-16
申请人： Simon Francis Brereton , Thomas Kemp , Rosie Burnell , Matthew Ekman
发明人： Simon Francis Brereton , Thomas Kemp , Rosie Burnell , Matthew Ekman
IPC分类号： A61M5/20 , A61M5/24 , A61M5/315
CPC分类号： A61M5/2033 , A61M5/20 , A61M5/2429 , A61M5/3157 , A61M2005/2013 , A61M2005/2073 , A61M2005/208 , A61M2205/581 , A61M2205/583
摘要： An auto-injector for administering a dose of a liquid medicament (M) is presented having an elongate case arranged to be held by a user, a tubular chassis telescoped in the case and biased against the case so as to protrude from the case. The injector also includes a syringe with a hollow injection needle, a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe. A trigger button is distally arranged in or on the case, wherein the trigger button is initially coupled to the case in a manner to protrude distally from the case and interlocked to the chassis in a manner preventing the trigger button from disengaging the case.

4. 发明授权

US09636459B2 Auto-injector 有权
公开(公告)号：US09636459B2
公开(公告)日：2017-05-02
申请号：US13983811
申请日：2012-02-16
申请人： Simon Francis Brereton , Thomas Kemp , Rosie Burnell , Matthew Ekman
发明人： Simon Francis Brereton , Thomas Kemp , Rosie Burnell , Matthew Ekman
IPC分类号： A61M5/20 , A61M5/24 , A61M5/315
CPC分类号： A61M5/3157 , A61M5/20 , A61M5/2033 , A61M5/2429 , A61M2005/2013 , A61M2005/206 , A61M2005/2073 , A61M2005/208 , A61M2205/581 , A61M2205/582 , A61M2205/583
摘要： An auto-injector for administering a dose of a liquid medicament (M) is presented having a tubular chassis telescopable in an elongate chassis, a carrier subassembly comprising a tubular carrier slidably arranged partially inside the chassis and inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle, a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. The auto-injector also has a control spring arranged around the carrier, a needle insertion control mechanism for coupling a proximal end of the control spring to either the carrier for advancing it for needle insertion or to the chassis, wherein the needle insertion control mechanism comprises a first collar biased by the control spring in a proximal direction (P), wherein at least one fifth clip is arranged on one of the chassis or the first collar initially abutting a block on the other of the chassis or the first collar.

5. 发明授权

US09623181B2 Auto-injector 有权
公开(公告)号：US09623181B2
公开(公告)日：2017-04-18
申请号：US13985021
申请日：2012-02-16
申请人： Simon Francis Brereton , Thomas Kemp , Rosie Burnell , Matthew Ekman
发明人： Simon Francis Brereton , Thomas Kemp , Rosie Burnell , Matthew Ekman
IPC分类号： A61M5/20 , A61M5/315 , A61M5/32 , A61M5/46 , A61M5/50
CPC分类号： A61M5/31501 , A61M5/2033 , A61M5/3157 , A61M5/3202 , A61M5/3204 , A61M5/3245 , A61M5/3257 , A61M5/326 , A61M5/46 , A61M5/5086 , A61M2005/206 , A61M2005/208 , A61M2005/3247 , A61M2205/581 , A61M2205/582
摘要： The invention relates to an auto-injector for administering a dose of a liquid medicament, comprising: an elongate tubular case, a carrier subassembly comprising a tubular carrier slidably arranged inside the case, the carrier adapted to contain a syringe with a hollow injection needle, a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier, wherein the drive spring acts between the carrier and the plunger, wherein the plunger in an initial state is locked to the carrier by a ramped engagement to the carrier and by being prevented from rotating out of this ramped engagement depending on a relative longitudinal position of the carrier in the case, wherein the plunger is arranged to be released for rotating out of the ramped engagement upon the needle reaching at least nearly a predefined injection depth on translation of the carrier in the proximal direction for advancing the needle beyond a proximal end of the auto-injector.

6. 发明申请

US20130324925A1 Auto-Injector 有权
标题翻译：自动进样器
公开(公告)号：US20130324925A1
公开(公告)日：2013-12-05
申请号：US13985021
申请日：2012-02-16
申请人： Simon Francis Brereton , Thomas Kemp , Rosie Burnell , Matthew Ekman
发明人： Simon Francis Brereton , Thomas Kemp , Rosie Burnell , Matthew Ekman
IPC分类号： A61M5/20
CPC分类号： A61M5/31501 , A61M5/2033 , A61M5/3157 , A61M5/3202 , A61M5/3204 , A61M5/3245 , A61M5/3257 , A61M5/326 , A61M5/46 , A61M5/5086 , A61M2005/206 , A61M2005/208 , A61M2005/3247 , A61M2205/581 , A61M2205/582
摘要： The invention relates to an auto-injector for administering a dose of a liquid medicament, comprising: an elongate tubular case, a carrier subassembly comprising a tubular carrier slidably arranged inside the case, the carrier adapted to contain a syringe with a hollow injection needle, a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier, wherein the drive spring acts between the carrier and the plunger, wherein the plunger in an initial state is locked to the carrier by a ramped engagement to the carrier and by being prevented from rotating out of this ramped engagement depending on a relative longitudinal position of the carrier in the case, wherein the plunger is arranged to be released for rotating out of the ramped engagement upon the needle reaching at least nearly a predefined injection depth on translation of the carrier in the proximal direction for advancing the needle beyond a proximal end of the auto-injector.
摘要翻译：本发明涉及一种用于给药液体药物的自动注射器，包括：细长的管状壳体，载体子组件，其包括可滑动地布置在壳体内的管状载体，载体适于容纳具有中空注射针的注射器，驱动弹簧和用于将驱动弹簧的负载传递到注射器的止动器的柱塞，其中注射器可锁定用于与载体的关节轴向平移，其中驱动弹簧作用在载体和柱塞之间，其中柱塞在初始状态通过与载体的倾斜接合而被锁定到载体上，并且根据载体在壳体中的相对纵向位置被阻止从该倾斜接合中旋转，其中柱塞被布置成被释放以旋转出针上的倾斜接合在载体在近端方向平移时达到至少几乎预定的注射深度使针超过自动注射器的近端。

7. 发明申请

US20130317428A1 AUTO-INJECTOR 有权
标题翻译：自动注射器
公开(公告)号：US20130317428A1
公开(公告)日：2013-11-28
申请号：US13983811
申请日：2012-02-16
申请人： Simon Francis Brereton , Thomas Kemp , Rosie Burnell , Matthew Ekman
发明人： Simon Francis Brereton , Thomas Kemp , Rosie Burnell , Matthew Ekman
IPC分类号： A61M5/20
CPC分类号： A61M5/3157 , A61M5/20 , A61M5/2033 , A61M5/2429 , A61M2005/2013 , A61M2005/206 , A61M2005/2073 , A61M2005/208 , A61M2205/581 , A61M2205/582 , A61M2205/583
摘要： An auto-injector for administering a dose of a liquid medicament (M) is presented having a tubular chassis telescopable in an elongate chassis, a carrier subassembly comprising a tubular carrier slidably arranged partially inside the chassis and inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle, a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. The auto-injector also has a control spring arranged around the carrier, a needle insertion control mechanism for coupling a proximal end of the control spring to either the carrier for advancing it for needle insertion or to the chassis, wherein the needle insertion control mechanism comprises a first collar biased by the control spring in a proximal direction (P), wherein at least one fifth clip is arranged on one of the chassis or the first collar initially abutting a block on the other of the chassis or the first collar.
摘要翻译：提供了一种用于施用剂量的液体药物（M）的自动注射器，其具有可伸缩在细长底盘中的管状底座，载体子组件，其包括可滑动地布置在底盘内部和壳体内部的管状载体，其中载体适应包含具有中空注射针的注射器，驱动弹簧和用于将驱动弹簧的负载传递到注射器的塞子的柱塞，其中注射器可锁定以与载体的关节轴向平移。所述自动注射器还具有围绕所述载体布置的控制弹簧，用于将所述控制弹簧的近端耦合到所述载体以将其前进用于针插入或到所述底架的针插入控制机构，其中所述针插入控制机构包括由所述控制弹簧沿近端方向（P）偏置的第一轴环，其中至少一个第五夹子布置在所述底盘或所述第一轴环中的一个上，最初邻接所述底盘或所述第一轴环的另一个上的块。

8. 发明申请

US20130296796A1 Auto-Injector 有权
标题翻译：自动进样器
公开(公告)号：US20130296796A1
公开(公告)日：2013-11-07
申请号：US13996145
申请日：2011-12-21
申请人： Yannick Hourmand , Simon Francis Brereton , Thomas Mark Kemp , Rosie Burnell , Matthew Ekman
发明人： Yannick Hourmand , Simon Francis Brereton , Thomas Mark Kemp , Rosie Burnell , Matthew Ekman
IPC分类号： A61M5/32 , A61M5/20
CPC分类号： A61M5/326 , A61M5/2033 , A61M5/24 , A61M5/46 , A61M2005/206 , A61M2005/208 , A61M2205/581 , A61M2205/582
摘要： The invention refers to an auto-injector for delivering a liquid medicament, comprising: an elongate housing arranged to contain a syringe with a hollow injection needle and a stopper, wherein the syringe is slidably arranged with respect to the housing, spring means capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position for insertion into the injection site, operating the syringe to inject the dose of medicament, and advancing a needle shroud over the needle for providing needle safety, activating means arranged to lock and release the spring means, wherein the spring means is a single drive spring in the shape of a compression spring grounded distally in the housing and proximally bearing against a thrust collar arranged to transmit load from the spring means via a plunger to the syringe and/or the stopper for needle insertion and injection, wherein the plunger is engageable to the thrust collar for joint axial translation, wherein the plunger is disengageable from the thrust collar on relative rotation so as to allow the thrust collar to be advanced further by the drive spring in order to engage the needle shroud for advancing it over the needle.
摘要翻译：本发明涉及一种用于输送液体药物的自动注射器，包括：细长壳体，布置成容纳具有中空注射针头和塞子的注射器，其中所述注射器相对于所述壳体可滑动地布置，激活时：将针从外壳内的覆盖位置推入到用于插入注射部位的前进位置，操作注射器以注射剂量的药物，并将针罩延伸到针上以提供针安全性，激活装置布置以锁定和释放弹簧装置，其中弹簧装置是在壳体中向远侧接地的压缩弹簧的形状的单个驱动弹簧，并且向近侧支承着布置成将负载从弹簧装置经由柱塞传递到注射器的止推环和/或用于针插入和注射的止动器，其中柱塞可接合到止推环用于关节轴向平移其中所述柱塞在相对旋转时可与所述止推环脱开，从而允许所述推力环通过所述驱动弹簧进一步前进，以便与所述针罩接合以将其推进到所述针上。

9. 发明申请

US20130204199A1 AUTO-INJECTOR 有权
标题翻译：自动注射器
公开(公告)号：US20130204199A1
公开(公告)日：2013-08-08
申请号：US13877495
申请日：2011-10-06
申请人： Yannick Hourmand , Simon Francis Brereton , Thomas Kemp , Rosie Burnell , Matthew Ekman
发明人： Yannick Hourmand , Simon Francis Brereton , Thomas Kemp , Rosie Burnell , Matthew Ekman
IPC分类号： A61M5/20
CPC分类号： A61M5/2033 , A61M5/3158 , A61M5/3202 , A61M5/3204 , A61M5/326 , A61M2005/2013 , A61M2005/206 , A61M2005/208 , A61M2205/581 , A61M2205/582
摘要： The invention refers to an auto-injector for administering a medicament (M), comprising of a chassis, a syringe with a hollow needle and a stopper; a drive spring capable of, upon activation: advancing the needle (3), injecting the medicament (M), and retracting the syringe with the needle after delivering the medicament (M); and; activating means arranged to lock and release the drive spring, wherein the drive spring is a compression spring arranged to be grounded at a distal end in the chassis for advancing the needle and for injecting the dose of medicament (M) via a plunger and wherein the drive spring is arranged to have its ground in the chassis switched to its proximal end for retracting the syringe. A refraction sleeve is axially movable arranged around the syringe, wherein the retraction sleeve is fixable in a maximum proximal position for providing ground at the distal end of the drive spring, wherein the retraction sleeve is arranged to take the syringe with it when released and translated in distal direction (D), wherein the compression spring is wrapped over the retraction sleeve with its distal end bearing against a thrust face on the retraction sleeve and with its proximal end bearing against a thrust collar arranged to be coupled to the plunger for joint axial translation for advancing the needle and for injecting the dose of medicament (M) and to decouple from the plunger for retraction.
摘要翻译：本发明涉及一种用于给药药物（M）的自动注射器，所述药物（M）包括底盘，具有中空针头的注射器和塞子; 驱动弹簧，其能够在激活后：递送所述针（3），注射所述药物（M），并且在递送所述药物（M）之后用所述针回缩所述注射器; 和; 激活装置，其布置成锁定和释放所述驱动弹簧，其中所述驱动弹簧是压缩弹簧，所述压缩弹簧布置成在所述底盘中的远端处接地，用于推进针头并且用于经由柱塞喷射剂量的药物（M），并且其中驱动弹簧布置成使其底盘中的地面切换到其近端以缩回注射器。折射套筒可围绕注射器轴向移动，其中缩回套筒可固定在最大近端位置，用于在驱动弹簧的远端处提供地面，其中缩回套筒布置成在释放和翻转时将注射器带入注射器在远端方向（D）上，其中压缩弹簧被卷绕在缩回套筒上，其远端轴承抵靠在缩回套筒上的止推面上，并且其近端轴承抵靠布置成联接到柱塞的止推环，用于接合轴向用于推进针头和用于注射剂量的药物（M）的平移并且与柱塞脱离以用于收缩。

10. 发明授权

US09925344B2 Auto-injector 有权
公开(公告)号：US09925344B2
公开(公告)日：2018-03-27
申请号：US13983809
申请日：2012-02-16
申请人： Simon Francis Brereton , Thomas Kemp , Rosie Burnell , Matthew Ekman
发明人： Simon Francis Brereton , Thomas Kemp , Rosie Burnell , Matthew Ekman
IPC分类号： A61M5/20 , A61M5/46 , A61M5/32 , A61M5/315
CPC分类号： A61M5/46 , A61M5/20 , A61M5/2033 , A61M5/3157 , A61M5/326 , A61M2005/206 , A61M2205/581 , A61M2205/582
摘要： An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.

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