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1. 发明授权

US08129517B1 Labeled solid supports for organic synthesis 有权
标题翻译：用于有机合成的标记固体支持物
公开(公告)号：US08129517B1
公开(公告)日：2012-03-06
申请号：US11751126
申请日：2007-05-21
申请人： Yakov A. Letuchy , William E. Martin , David W. Muller , Shawn Allen , Shawn P. Walsh
发明人： Yakov A. Letuchy , William E. Martin , David W. Muller , Shawn Allen , Shawn P. Walsh
IPC分类号： C07H21/00 , C08B15/06 , A61K38/00 , C07K16/00
CPC分类号： C08L23/02 , C08L2205/02
摘要： The disclosed invention pertains to improved oligonucleotide manufacturing methods, including novel support compositions that are optionally labeled, their methods of preparation and use. The compositions and methods are particularly well suited for high throughput oligonucleotide manufacturing in that the automated support recognition facilitates loading of the wells with the proper supports. In addition, the labeled supports can be used to confirm that each well of a multi-well plate, such as a 96 or 384 well plate, was properly loaded.
摘要翻译：所公开的发明涉及改进的寡核苷酸制备方法，包括任选地标记的新型载体组合物，其制备和使用方法。组合物和方法特别适用于高通量寡核苷酸制造，因为自动化支持识别有利于用合适的载体加载孔。此外，标记的载体可用于确认多孔板（例如96孔或384孔板）的每个孔都被适当地加载。

2. 发明授权

US6040379A Starch copolymer products and process 有权
标题翻译：淀粉共聚物产品及工艺
公开(公告)号：US6040379A
公开(公告)日：2000-03-21
申请号：US133625
申请日：1998-08-13
申请人： Gary Luebke , Kenneth Curtis Benton , Yakov A. Letuchy
发明人： Gary Luebke , Kenneth Curtis Benton , Yakov A. Letuchy
IPC分类号： C08B31/00 , C08F251/00 , C08L3/04
CPC分类号： C08B31/00 , C08F251/00
摘要： The invention provides methods for the preparation of a starch copolymer product which is the reaction product of starch and one or more synthetic monomers capable of undergoing free radical polymerization wherein the reaction product is in the form of an emulsion or dispersion having weight-average particle sizes less than 180 nm as measured by Capillary Hydrodynamic Fractionation. The method includes the steps of: (a) dissolving or colloidally dispersing starch in an aqueous solvent to form a starch solution or dispersion; (b) heating the starch solution or dispersion to a specified temperature range; (c) adding to the starch solution or dispersion a first portion of the synthetic monomer and a free radical initiator for initiation of polymerization of the starch member and the synthetic monomer; and (d) after free radical polymerization of the synthetic monomers has been initiated in the presence of the starch, adding additional portions of synthetic monomers capable of undergoing free radical polymerization to the starch solution or dispersion. The invention also provides improved methods for the preparation of starch copolymer products utilizing wet adhesion monomers and improved industrial and architectural coatings containing the resulting starch copolymer products.
摘要翻译：本发明提供了制备淀粉共聚物产物的方法，淀粉共聚物产物是能够进行自由基聚合的淀粉和一种或多种合成单体的反应产物，其中反应产物是具有重均粒径的乳液或分散体的形式通过毛细管流体动力学分级测量小于180nm。该方法包括以下步骤：（a）将淀粉溶解或胶体分散在水性溶剂中以形成淀粉溶液或分散体; （b）将淀粉溶液或分散体加热至规定的温度范围; （c）向淀粉溶液或分散体中加入合成单体的第一部分和用于引发淀粉组分和合成单体聚合的自由基引发剂; 和（d）在淀粉存在下开始合成单体的自由基聚合之后，向淀粉溶液或分散体中加入另外部分能够进行自由基聚合的合成单体。本发明还提供了使用湿粘合单体和改进的含有所得淀粉共聚物产物的工业和建筑涂料来制备淀粉共聚物产物的改进方法。

3. 发明授权

US06593414B2 Pressure sensitive adhesives 失效
公开(公告)号：US06593414B2
公开(公告)日：2003-07-15
申请号：US09909222
申请日：2001-07-19
申请人： Kenneth C. Benton , Yakov A. Letuchy , Edward G. Ludwig, Jr. , James M. Quarles
发明人： Kenneth C. Benton , Yakov A. Letuchy , Edward G. Ludwig, Jr. , James M. Quarles
IPC分类号： C08L300
CPC分类号： C09J109/06 , C08L2666/02 , C08L2666/26 , C09J103/04
摘要： Pressure sensitive adhesive compositions comprising (a) a synthetic polymer latex; and (b) an aqueous dispersion of thinned, derivatized starch are disclosed.

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