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1. 发明申请

WO2008133358A1 SCAFFOLDS INCREASED SPECIFIC GRAVITY FOR CELL CULTURE AND METHOD FOR MANUFACTURING THEREOF 审中-公开
标题翻译： SCAFFOLDS提高细胞培养的特异性重要性及其制造方法
公开(公告)号：WO2008133358A1
公开(公告)日：2008-11-06
申请号：PCT/KR2007/002065
申请日：2007-04-27
申请人： YANG, Hyunjin , LEE, Heeyoung , LEE, Jun Seok
发明人： YANG, Hyunjin , LEE, Heeyoung , LEE, Jun Seok
IPC分类号： C12N5/08 , C12N5/00
CPC分类号： C12N5/0075 , C12N2533/10 , C12N2533/40
摘要： The present invention relates to microtype scaffolds for cell culture, which have their specific gravity increased and a method for manufacturing thereof, and more specifically, relates to microtype scaffolds for cell culture, which have their specific gravity increased, by adding a chemically stable inorganic compound having a high specific gravity in manufacturing biocompatible polymer microtype scaffolds for cell culture and a method for manufacturing thereof. In case where the inventive microtype scaffolds for cell culture is used, it is easy to separate cells cultured on microtype scaffolds, and cell damage can be minimized by reducing separation time, and it is easy to recover cells due to a definite boundary layer.
摘要翻译：本发明涉及具有比重增加的细胞培养用微型支架及其制造方法，更具体地，涉及通过添加化学稳定的无机化合物而使其比重增加的细胞培养用微型支架在生产用于细胞培养的生物相容性聚合物微型支架中具有高比重及其制造方法。在使用本发明的用于细胞培养的微型支架的情况下，容易分离在微型支架上培养的细胞，并且通过减少分离时间可以最小化细胞损伤，并且由于确定的边界层容易回收细胞。

2. 发明申请

WO2008143402A1 LIPID-FREE SCAFFOLDS FOR HUMAN VOLUME REPLACEMENT OR CELL CULTURE AND USE THEREOF 审中-公开
标题翻译：用于人体容量更换或细胞培养的无脂质免疫球蛋白及其用途
公开(公告)号：WO2008143402A1
公开(公告)日：2008-11-27
申请号：PCT/KR2008/001632
申请日：2008-03-24
申请人： LEE, Heeyoung , YANG, Hyunjin , LEE, Jun Seok , CHOI, Ji Suk
发明人： LEE, Heeyoung , YANG, Hyunjin , LEE, Jun Seok , CHOI, Ji Suk
IPC分类号： A61L27/56
CPC分类号： A61L27/3604 , A61L27/3683 , A61L2430/40
摘要： The present invention relates to lipid removed scaffolds(lipid-free scaffolds) for human tissue volume replacement or cell culture. More particularly, the present invention relates to a method for preparing lipid removed scaffolds(lipid-free scaffolds) for human tissue volume replacement or cell culture, the method comprising the steps of: fragmenting fat tissue to isolate lipids by ultrasonic treatment or high pressure nozzle spray; removing the isolated lipids and fat tissue from which lipids were not isolated to sterilize. According to the present invention, lipids are removed from fat tissue only by physical treatment to maintain the volume thereof and microstructures such as cellular membrane as much as possible and thus the inventive scaffolds are useful for human tissue volume replacement.
摘要翻译：本发明涉及用于人组织体积替换或细胞培养的脂质移除的支架（无脂质支架）。更具体地说，本发明涉及一种用于制备用于人体组织体积置换或细胞培养的脂质去除的支架（无脂质支架）的方法，所述方法包括以下步骤：通过超声处理或高压喷嘴使脂肪组织分离以分离脂质喷雾; 去除未分离脂质的分离的脂质和脂肪组织进行灭菌。根据本发明，仅通过物理处理从脂肪组织中除去脂质以尽可能多地保持其体积和微细结构如细胞膜，因此本发明的支架可用于人体组织体积更换。

3. 发明申请

WO2011162511A2 TUBE-TYPE MEDICAL NEEDLE UNIT AND METHOD OF INSERTING PLURALITY OF MEDICAL SUTURES INTO TUBE-TYPE MEDICAL NEEDLE 审中-公开
标题翻译：管型医用针头单元及将医用多功能插入医用针头的方法
公开(公告)号：WO2011162511A2
公开(公告)日：2011-12-29
申请号：PCT/KR2011/004469
申请日：2011-06-20
申请人： LEE, Heeyoung , YANG, Hyunjin
发明人： LEE, Heeyoung , YANG, Hyunjin
IPC分类号： A61B17/06 , A61M25/01 , A61M5/158 , A61B17/34
CPC分类号： A61B17/06066 , A61B17/06 , A61B2017/00792 , A61B2017/0477 , A61B2017/06052 , A61B2017/06176 , Y10T29/49826
摘要： Provided are a tube-type medical needle unit and a method of mounting a plurality of medical sutures in a tube-type needle. The tube-type medical needle unit includes a tube-type needle including an end in the shape of a probe and including a communication hole formed therein to communicate the end with another end and a plurality of sutures inserted into the communication hole of the tube-type needle, the sutures including adhesion protrusions formed on surfaces thereof, in which the plurality of sutures are arranged in parallel and mounted in the tube-type needle.
摘要翻译：提供一种管式医用针单元以及将多根医用缝线安装在管型针中的方法。管型医用针单元包括管型针，其包括探针形状的端部，并且包括形成在其中的连通孔，用于将端部与另一端连通，以及插入管状医疗针的连通孔中的多个缝合线，所述缝合线包括在其表面上形成的粘附突起，其中所述多个缝线平行布置并安装在所述管型针中。

4. 发明申请

WO2012011791A3 FIXING METHOD OF LIVING TISSUE, TUBE-TYPE NEEDLE PACKAGE AND USING METHOD THEREOF 审中-公开
公开(公告)号：WO2012011791A3
公开(公告)日：2012-01-26
申请号：PCT/KR2011/005455
申请日：2011-07-25
申请人： YANG, Hyunjin , LEE, Heeyoung
发明人： YANG, Hyunjin , LEE, Heeyoung
IPC分类号： A61D1/00 , A61D3/00 , A61B17/04
摘要： A fixing method of a living tissue by which a tube-type needle package is inserted into a living skin of an animal to fix first and second fixing tissue parts of the living skin to each other, a tube-type needle package and a using method thereof are disclosed. The fixing method includes: inserting a tube-type needle into the living skin, wherein a suture including adhesive projections has been inserted into the tube-type needle, and the adhesive projections have been formed on a surface of the suture; thrusting the tube-type needle into the living skin so that an end part of the inserted tube-type needle is located up to the first fixing tissue part of the living skin and forcing an end of the suture to adhere to the first fixing tissue part; moving the tube-type needle back and forth so that the suture, the end of which has adhered to the first fixing tissue part, extends in zigzags in a direction approximately horizontal with respect to an insertion direction of the tube-type needle inside the first fixing tissue part so as to adhere to the first fixing tissue part; and moving the needle to the second fixing tissue part so that the suture adheres to the second fixing tissue part.

5. 发明申请

WO2008136549A1 TOOLS FOR FIBER REINFORCED ANTI-COMPRESSIVE ADHERENT SUTURE METHOD 审中-公开
标题翻译：用于纤维增强抗压缩附件方法的工具
公开(公告)号：WO2008136549A1
公开(公告)日：2008-11-13
申请号：PCT/KR2007/002263
申请日：2007-05-08
申请人： YANG, Hyunjin , LEE, Heeyoung
发明人： YANG, Hyunjin , LEE, Heeyoung
IPC分类号： A61B17/06 , A61B17/04
CPC分类号： A61B17/06166 , A61B17/24 , A61B2017/00792 , A61B2017/06176
摘要： Disclosed therein are instruments necessary for a surgical operation performed to keep a length of lengthened tissues, for instance, a raised nose on the face, using an improved thread embedded in a living body. More particularly, the present invention provides instruments for a fiber reinforced ant i -compressive adherent suture method used to lengthen or separate soft tissues in the living body, which includes a tissue-implantable thread inserted into the living body by an injector needle and having wedge- shaped protrusions of different directionalities formed in two sections thereof, an injector for inserting the injector needle into the living body and moving it forwardly and backwardly, an instrument for inserting the tissue-implantable thread into the injector, and an instrument for vertically splitting an end of the thread to make the thread act in the living body.
摘要翻译：其中公开了使用嵌入生物体中的改进的线来进行外科手术所需的器械，以保持延长的组织的长度，例如面部上的凸起的鼻子。更具体地说，本发明提供了一种用于延长或分离生物体中的软组织的纤维增强蚂蚁i压缩粘合缝合方法的装置，其包括通过注射针插入生物体中的组织可植入线，并具有楔形形成在其两个部分中的不同方位的形状的突起，用于将注射器针插入生物体并将其向前和向后移动的注射器，用于将组织可植入线插入到注射器中的仪器，以及用于垂直分割线的末端使线作用于活体。

6. 发明申请

WO2007136227A1 NON-SPHERICAL THREE-DIMENSIONAL MICRO-SCAFFOLD FOR CELL CULTURE AND DELIVERY PREPARED USING RAPID PROTOTYPING SYSTEM 审中-公开
标题翻译：用于细胞培养和交付的非球形三维微型SCAFFOLD使用快速原型系统
公开(公告)号：WO2007136227A1
公开(公告)日：2007-11-29
申请号：PCT/KR2007/002494
申请日：2007-05-23
申请人： YANG, Hyunjin
发明人： YANG, Hyunjin
IPC分类号： C12M3/00
CPC分类号： C12N5/0075 , B33Y70/00 , B33Y80/00 , C12M25/14 , C12M25/16 , C12N2533/30 , C12N2533/40 , C12N2533/54
摘要： The present invention provides a three-dimensional non-spherical micro-scaffold for cell culture and delivery. The micro-scaffold is prepared using a biocompatible polymer selected from the group consisting of PLA, PLLA, PGA, PGLA, PCL, chitosan, polylactides, polyglycolides, epsilon-caprolactone, polyhydroxyvaleric acid, polyhydroxybutyric acid, other polyhydroxy acids, polytrimethylene carbonate, polyamines, vinyl polymers, polyacrylic acids and their derivatives containing ester, polyethylene glycols, polydioxanones, polycarbonates, polyacetals, polyorthoesters, polyamino acids, polyphosphoesters, polyesteramides, polyfumerates, polyanhydrides, polycyanoacrylates, polyoxamers, polyurethanes, polyphosphazenes, aliphatic polyesters, poly(amino acid), copoly(ether-ester), polyakylene oxalate, polyamides, poly(iminocarbonate), polyoxaester, polyamidoesters, amine group-containing polyoxaester, polyacetal, polyalkanoate, gelatin, collagen, elastine, polysaccharide, alginate, chitin, hyaluronic acid, and combinations thereof, as a biocompatible polymer for use in the in vitro culture and in vivo injection of adult stem cells, by a RP (rapid prototyping) system with a spry nozzle. The three-dimensional micro-scaffold have a Moebius strip-shaped, twisted band or twisted tubular structure, which has a one or two or more twists, such that one side of the strip is connected to the other side in an upside-down manner without intermittence, and thus there is no distinction between the inside and outside surfaces. Alternatively, the structure has a Klein bottle- or Klein jar-like twisted bottle or twisted tubular structure, in which the inlet and outlet of the structure meet each other through a surface of the outer wall of the structure, so that the inlet and the outlet are one and the same.
摘要翻译：本发明提供用于细胞培养和递送的三维非球形微支架。使用选自PLA，PLLA，PGA，PGLA，PCL，壳聚糖，聚丙交酯，聚乙交酯，ε-己内酯，聚羟基戊酸，聚羟基丁酸，其它多羟基酸，聚三亚甲基碳酸酯，多胺的生物相容性聚合物制备微支架乙烯基聚合物，聚丙烯酸及其衍生物含有酯，聚乙二醇，聚二恶烷酮，聚碳酸酯，聚缩醛，聚原酸酯，聚氨基酸，聚磷酸酯，聚酯酰胺，聚芳香酸酯，聚酐，聚氰基丙烯酸酯，聚氧乙烯，聚氨酯，聚磷腈，脂族聚酯，聚（氨基酸），共聚（醚 - 酯），草酸亚芳基酯，聚酰胺，聚（亚氨基碳酸酯），聚氧酯，聚酰胺酯，含胺基的聚氧化酯，聚缩醛，聚链烷酸酯，明胶，胶原，弹性蛋白，多糖，藻酸盐，甲壳素，透明质酸及其组合，作为用于体外培养和体内的生物相容性聚合物注射成人干细胞，通过RP（快速成型）系统与spry喷嘴。三维微支架具有Moebius带状，扭曲带或扭曲的管状结构，其具有一个或两个或更多个扭曲，使得带的一侧以倒置的方式连接到另一侧没有间歇，因此内表面和外表面之间没有区别。或者，该结构具有Klein瓶或Klein罐状扭转瓶或扭曲的管状结构，其中结构的入口和出口通过结构的外壁的表面相互相遇，使得入口和出口是一样的。

7. 发明申请

WO2011030978A1 SOLAR CELL 审中-公开
标题翻译：太阳能电池
公开(公告)号：WO2011030978A1
公开(公告)日：2011-03-17
申请号：PCT/KR2010/001034
申请日：2010-02-19
申请人： LG ELECTRONICS INC. , YANG, Hyunjin , CHOI, Junghoon , JI, Kwangsun , LEE, Heonmin
发明人： YANG, Hyunjin , CHOI, Junghoon , JI, Kwangsun , LEE, Heonmin
IPC分类号： H01L31/042
CPC分类号： H01L31/0368 , H01L31/02167 , H01L31/022466 , H01L31/03682 , H01L31/0682 , H01L31/0747 , H01L31/077 , Y02E10/546 , Y02E10/547
摘要： A solar cell is shown. The solar cell includes a semiconductor substrate of a first conductive type; a first amorphous semiconductor layer including a crystalline portion; a first electrode portion on the semiconductor substrate; and a second electrode portion on the semiconductor substrate.
摘要翻译：显示一个太阳能电池。太阳能电池包括第一导电类型的半导体衬底; 包括结晶部分的第一非晶半导体层; 半导体衬底上的第一电极部分; 和半导体衬底上的第二电极部分。

8. 发明申请

WO2008133362A1 PROLIFERATION CULTURE METHODS USING MICRO-SCAFFOLDS FOR REGULATIONS OF CELL-TO-CELL SIGNALS 审中-公开
标题翻译：使用微细胞扩增细胞 - 细胞信号调节的增殖培养方法
公开(公告)号：WO2008133362A1
公开(公告)日：2008-11-06
申请号：PCT/KR2007/002108
申请日：2007-04-28
申请人： YANG, Hyunjin
发明人： YANG, Hyunjin
IPC分类号： C12N5/08 , C12N5/00
CPC分类号： C12N5/0075 , C12N2533/40
摘要： The present invention aims to provide a three-dimensional cell culture method for increasing cell proliferation efficiency by suitably regulating the proliferation-inducing and proliferation-inhibitory signals between cells, which are the greatest variables in proliferation efficiency. For this purpose, the present invention provides a method for culturing cells using micro-scaffolds by the regulation of cell-to-cell signals, the method comprising repeatedly performing any one or both of the following processes a) and b) so as to regulate proliferation-inducing and proliferation- inhibitory signals between the cells: a) a process of gradually adding the micro-scaffolds, in which a small amount of the micro-scaffolds are used in an initial stage in order to maintain a suitable distance between the cells (cell concentration relative to the micro-scaffolds), and the amount of the micro-scaffolds is then increased slowly according to cell proliferation rate! and b) a periodic shaking process, in which shaking is performed in order to separate connected cells from each other by a physical force, after the cells are incubated for more than a given period of time.
摘要翻译：本发明旨在提供一种三维细胞培养方法，其通过适当调节细胞之间的增殖诱导和增殖抑制信号来提高细胞增殖效率，这是增殖效率的最大变量。为此，本发明提供了通过调节细胞间细胞信号来使用微支架培养细胞的方法，所述方法包括重复进行以下过程a）和b）中的任何一个或两个以调节细胞之间的增殖诱导和增殖抑制信号：a）逐渐加入微支架的过程，其中在初始阶段使用少量微支架以便在细胞之间保持适当的距离（相对于微支架的细胞浓度），然后根据细胞增殖率缓慢增加微支架的量！和b）周期性振荡过程，其中在细胞孵育超过给定时间段之后，进行摇动以便通过物理力将相互连接的细胞彼此分离。

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