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1. 发明授权

US09498519B2 Amyloid-beta clearance 有权
标题翻译：淀粉样蛋白-β清除
公开(公告)号：US09498519B2
公开(公告)日：2016-11-22
申请号：US13701332
申请日：2010-07-23
申请人： Woo Jin Park , Hye-eun Han
发明人： Woo Jin Park , Hye-eun Han
IPC分类号： A61K38/48 , A61K48/00 , C12N9/50 , A61K38/46 , A61K38/43
CPC分类号： A61K38/4873 , A61K48/005 , C12N9/506 , C12N2740/15043 , C12N2770/34022 , C12N2770/34033 , C12N2770/34071 , C12Y304/22044
摘要： The present invention relates to a pharmaceutical composition for preventing or treating an amyloid β-caused disease, which comprises as an active ingredient a NIa (nuclear inclusion a) protease or a gene carrier containing a nucleotide sequence encoding the NIa protease. The pharmaceutical composition of this invention is very effective to treat a variety of diseases or disorders, inter alia, Alzheimer's disease.
摘要翻译：本发明涉及一种用于预防或治疗淀粉样蛋白β引起的疾病的药物组合物，其包含作为活性成分的NIa（核包涵体a）蛋白酶或含有编码NIa蛋白酶的核苷酸序列的基因载体。本发明的药物组合物非常有效地治疗各种疾病或病症，尤其是阿尔茨海默氏病。

2. 发明申请

US20130108613A1 AMYLOID-BETA CLEARANCE 有权
公开(公告)号：US20130108613A1
公开(公告)日：2013-05-02
申请号：US13701332
申请日：2010-07-23
申请人： Woo Jin Park , Hye-eun Han
发明人： Woo Jin Park , Hye-eun Han
IPC分类号： A61K38/48 , A61K48/00
CPC分类号： A61K38/4873 , A61K48/005 , C12N9/506 , C12N2740/15043 , C12N2770/34022 , C12N2770/34033 , C12N2770/34071 , C12Y304/22044
摘要： The present invention relates to a pharmaceutical composition for preventing or treating an amyloid β-caused disease, which comprises as an active ingredient a NIa (nuclear inclusion a) protease or a gene carrier containing a nucleotide sequence encoding the NIa protease. The pharmaceutical composition of this invention is very effective to treat a variety of diseases or disorders, inter alia, Alzheimer's disease.
摘要翻译：本发明涉及用于预防或治疗淀粉样蛋白β-引起的疾病的药物组合物，其包含作为活性成分的NIa（核包涵体a）蛋白酶或含有编码NIa蛋白酶的核苷酸序列的基因载体。本发明的药物组合物非常有效地治疗各种疾病或病症，尤其是阿尔茨海默氏病。

3. 发明授权

US08083647B2 Treadmill system and operating method of the same 有权
标题翻译：跑步机系统及操作方法相同
公开(公告)号：US08083647B2
公开(公告)日：2011-12-27
申请号：US12778105
申请日：2010-05-11
申请人： Woo Jin Park
发明人： Woo Jin Park
IPC分类号： A63B71/00
CPC分类号： A63B71/0622 , A63B22/02 , A63B24/0062 , A63B2071/0636 , A63B2071/0638 , A63B2071/0644 , A63B2071/0647 , A63B2220/05 , A63B2220/807 , A63F2300/1093 , A63F2300/6027 , A63F2300/69 , Y10S482/901
摘要： Provided is a treadmill-related technology. That is, the treadmill device and the operating method of the same is configured to detect a user who is taking exercise in real time, take pictures of the detected user's looks, and insert user image data as the results of data analysis, which are obtained from the taken pictures, into a virtual 3D object moving image which indicates the selected exercise course background, so as to project a 3D user image in which the user's behavior patterns are engaged with a virtual 3D object moving image. Therefore, since the treadmill device is used to allow a user to see his own looks taking exercise in real time, it is possible to prevent the user from feeling boring during exercise, and it is easy to continuously check the user's own physical status or conditions. Also, since a user may actively employ exercise course backgrounds which are freely changed during exercise by the user's choices, the best information on the physical rhythm and exercise conditions may be offered to the user, thereby improving the user's satisfaction and buying power, which leads to an expected increase in the sales.
摘要翻译：提供了一种与跑步机相关的技术。也就是说，跑步机装置及其操作方法被配置为检测正在进行锻炼的用户，拍摄检测到的用户的外观，并插入用户图像数据作为数据分析的结果，这是获得的从所拍摄的图像转换为指示所选择的运动过程背景的虚拟3D对象运动图像，以投射用户的行为模式与虚拟3D对象运动图像相关联的3D用户图像。因此，由于使用跑步机装置实时观看自己的外观，所以可以防止使用者在运动中感到无聊，容易连续检查用户自身的身体状况或状况。此外，由于用户可以主动地使用在运动期间由用户的选择自由改变的运动课程背景，可以向用户提供关于身体节奏和运动条件的最佳信息，从而提高用户的满意度和购买力，这导致预计销售额增加。

4. 发明授权

US08212163B2 Withdrawable device of vacuum circuit breaker 有权
标题翻译：真空断路器抽出式装置
公开(公告)号：US08212163B2
公开(公告)日：2012-07-03
申请号：US12780113
申请日：2010-05-14
申请人： Woo Jin Park , Hyun Jae Kim
发明人： Woo Jin Park , Hyun Jae Kim
IPC分类号： H01H9/20
CPC分类号： H02B11/127
摘要： A withdrawable device of a vacuum circuit breaker for transferring a vacuum circuit breaker received in a cradle, includes: a carriage on which the vacuum circuit breaker is loaded; a first transfer unit fixed to the carriage; a second transfer unit installed at one side of the cradle such that it can be driven, and transferring a transfer force to the first transfer unit; and a transfer limiting unit for selectively limiting driving of the second transfer unit.
摘要翻译：用于传送接收在支架中的真空断路器的真空断路器的抽出装置包括：承载真空断路器的托架; 固定到托架上的第一传送单元; 第二转印单元，其安装在所述支架的一侧，使得其能够被驱动，并且将转印力传递到所述第一转印单元; 以及用于选择性地限制第二传送单元的驱动的传送限制单元。

5. 发明授权

US5976277A High speed tool steel, and manufacturing method therefor 失效
标题翻译：高速工具钢及其制造方法
公开(公告)号：US5976277A
公开(公告)日：1999-11-02
申请号：US853110
申请日：1997-05-08
申请人： Woo Jin Park , Eon Sik Lee , Sang Ho Ahn
发明人： Woo Jin Park , Eon Sik Lee , Sang Ho Ahn
IPC分类号： B22F3/115 , C21D6/00 , C21D8/00 , C22C33/02 , C22C38/22 , C22C38/24 , C22C38/30 , C22C38/36 , B21J1/00 , C21D5/00
CPC分类号： C22C38/36 , B22F3/115 , C21D8/005 , C22C33/0285 , C22C38/22 , C22C38/24 , C22C38/30 , C21D2211/003 , C21D6/007
摘要： A high speed tool steel and a manufacturing method therefor are disclosed, in which carbides are formed in the matrix in a uniform manner, thereby obtaining a high toughness and a high abrasion resistance. The high speed tool steel according to the present invention includes a basic composition of W.sub.a Mo.sub.b Cr.sub.c Co.sub.d V.sub.x C.sub.y Fe.sub.z where the subscripts meet in weight %: 5.0%.ltoreq.a.ltoreq.7.0%, 4.0%.ltoreq.b.ltoreq.6.0%, 3.0%.ltoreq.c.ltoreq.5.0%, 6.5%.ltoreq.d.ltoreq.9.5%, 2.2%.ltoreq.x.ltoreq.8.3%, 1.1%.ltoreq.y.ltoreq.2.18%, and 66.52%.ltoreq.z.ltoreq.73.7%. The final structure has carbides uniformly distributed within a martensite matrix, which are mainly MC and M.sub.6 C carbides. The method includes the steps of melting the above-defined alloy composition, gas spraying the melted alloy to form a bulk material, heat treating the bulk material to decompose the M.sub.2 C carbides to stabilize M.sub.6 C carbides and hot working the heat treated bulk material to a desired shape.
摘要翻译：公开了一种高速工具钢及其制造方法，其中以均匀的方式在基体中形成碳化物，从而获得高韧性和高耐磨性。根据本发明的高速工具钢包括WaMobCrcCodVxCyFez的基本组成，其中下标满足重量百分比：5.0％

6. 发明授权

US5517478A Disc player for performing disc loading and ejecting in response to opening and closing of lid 失效
标题翻译：用于响应于盖的打开和关闭执行盘装载和弹出的盘播放器
公开(公告)号：US5517478A
公开(公告)日：1996-05-14
申请号：US281017
申请日：1994-07-27
申请人： Woo Jin Park
发明人： Woo Jin Park
IPC分类号： G11B17/03 , G11B17/04 , G11B17/043 , G11B33/02
CPC分类号： G11B17/0407 , G11B33/027
摘要： A disc player performs disc loading and ejecting while closing and opening the player lid. The disc player includes a housing having a first guide groove longitudinally formed on an inner side thereof, a deck including a turntable, a moving plate mounted over deck to horizontally move in frontward and rearward directions, a disc tray engaged with the moving plate and for loading and ejecting a disc onto and out of the turntable while vertically moving down and up in response to rearward and frontward movements of the moving plate, a lid engaged with the housing to pivotally close and open, and movement mechanism for controlling the frontward and rearward movements of the moving plate when the lid closes and opens. A simple structure and miniaturization of a disc player can be accomplished since disc loading and ejecting is performed without using a motor and gears.
摘要翻译：光盘播放机在关闭并打开播放器盖时执行光盘加载和弹出。光盘播放器包括具有纵向形成在其内侧的第一引导槽的壳体，包括转盘的甲板，安装在甲板上的移动板，以在前后方向上水平移动;与移动板接合的盘托架，响应于移动板的向后和向前的运动而垂直向上和向下移动盘，将盘弹出和离开转盘，与壳体接合以枢转闭合和打开的盖以及用于控制前后的移动机构当盖关闭并打开时移动板的移动。可以实现盘播放机的简单结构和小型化，因为在不使用电动机和齿轮的情况下执行盘装载和弹出。

7. 发明申请

US20110245179A1 Composition for Prevention or Treatment of Heart Failure 审中-公开
标题翻译：预防或治疗心力衰竭的组合物
公开(公告)号：US20110245179A1
公开(公告)日：2011-10-06
申请号：US13119328
申请日：2009-09-17
申请人： Woo Jin Park , Jae Gyun Oh
发明人： Woo Jin Park , Jae Gyun Oh
IPC分类号： A61K38/10 , A61K31/381 , A61K31/4965 , A61K31/497 , A61P9/10
CPC分类号： A61K31/00 , A23L33/10 , A23V2002/00 , A61K31/381 , A61K31/496 , A23V2200/326
摘要： Provided are a composition for preventing or treating heart failure and a method for screening an agent for treating heart failure. The present disclosure demonstrates for the first time that administration of PKCζ inhibitor provides inotropic effect by increasing myocardial contractility. Thus, the present disclosure will contribute greatly to the prevention or treatment of heart failure. Also, since the present disclosure is based on the change in calcium sensitivity in cardiac myocytes unlike the existing inotropic agents, it can enhance the myocardial contractility without increasing oxygen demand or the risk of arrhythmia.
摘要翻译：提供了用于预防或治疗心力衰竭的组合物和筛选用于治疗心力衰竭的药剂的方法。本公开第一次证实PKCζ抑制剂的施用通过增加心肌收缩力来提供变力作用。因此，本公开将有助于预防或治疗心力衰竭。此外，由于本公开内容是基于心肌细胞中钙敏感性的变化而不同于现有的肌力药物，所以它可以增加心肌收缩力而不增加氧需求或心律失常的风险。

8. 发明授权

US06200394B1 High speed tool steel 有权
标题翻译：高速工具钢
公开(公告)号：US06200394B1
公开(公告)日：2001-03-13
申请号：US09385267
申请日：1999-08-30
申请人： Woo Jin Park , Eon Sik Lee , Sang Ho Ahn
发明人： Woo Jin Park , Eon Sik Lee , Sang Ho Ahn
IPC分类号： C22C3830
CPC分类号： C22C38/36 , B22F3/115 , C21D6/007 , C21D8/005 , C21D2211/003 , C22C33/0285 , C22C38/22 , C22C38/24 , C22C38/30
摘要： A high speed tool steel and a manufacturing method therefor are disclosed, in which carbides are formed in the matrix in a uniform manner, thereby obtaining a high toughness and a high abrasion resistance. The high speed tool steel according to the present invention includes a basic composition of WaMobCrcCodVxCyFez where the subscripts meet in weight %: 5.0%≦a≦7.0%, 4.0%≦b≦6.0%, 3.0%≦c≦5.0%, 6.5%≦d≦9.5%, 2.2% ≦x≦8.3%, 1.1%≦y≦2.18%, and 66.52%≦z≦73.7%. The final structure has carbides uniformly distributed within a martensite matrix, which are mainly MC and M6C carbides. The method includes the steps of melting the above-defined alloy composition, gas spraying the melted alloy to form a bulk material, heat treating the bulk material to decompose the M2C carbides to stabilize M6C carbides and hot working the heat treated bulk material to a desired shape.
摘要翻译：公开了一种高速工具钢及其制造方法，其中以均匀的方式在基体中形成碳化物，从而获得高韧性和高耐磨性。根据本发明的高速工具钢包括WaMobCrcCodVxCyFez的基本组成，其中下标以重量％满足：5.0％<= a <= 7.0％，4.0％<= b <= 6.0％，3.0％<= = 5.0％，6.5％<= d <= 9.5％，2.2％<= x <= 8.3％，1.1％<= y <= 2.18％和66.52％<= z <= 73.7％。最终结构具有均匀分布在马氏体基体内的碳化物，主要是MC和M6C碳化物。该方法包括以下步骤：熔化上述合金组成，气体喷射熔化的合金以形成散装材料，热处理散装材料以分解M2C碳化物以稳定M6C碳化物并将热处理的散装材料热加工成所需的形状。

9. 发明授权

US09855315B2 Pharmaceutical composition comprising CCN5 for reducing cardiac fibrosis in a subject in need thereof 有权
公开(公告)号：US09855315B2
公开(公告)日：2018-01-02
申请号：US13636500
申请日：2011-03-10
申请人： Woo Jin Park , Pyoung Oh Yoon , Dong Kwon Yang
发明人： Woo Jin Park , Pyoung Oh Yoon , Dong Kwon Yang
IPC分类号： A61K48/00 , A61K38/18 , C07K14/475 , G01N33/68 , A61K31/7088 , A61K38/17 , A01K67/027
CPC分类号： A61K38/18 , A01K67/0275 , A61K31/7088 , A61K38/179 , C07K14/475 , C12N2799/022 , G01N33/6893 , G01N2800/325
摘要： The present invention relates to a pharmaceutical composition for preventing or treating a heart failure and a method for screening a therapeutic agent for preventing or treating a heart failure. The pharmaceutical composition of the present disclosure comprises the CCN5 or CCN2ΔCT protein, or a genetic carrier comprising a nucleotide sequence encoding the CCN5 or the CCN2ΔCT protein, exhibiting dramatic prevention or treatment efficacies on a heart failure even without surgical treatments accompanied with transplanting a donor heart.

10. 发明申请

US20130345130A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING HEART FAILURE AND METHOD FOR SCREENING AGENT FOR PREVENTING OR TREATING HEART FAILURE 有权
标题翻译：用于预防或治疗心脏衰竭的药物组合物和筛选用于预防或治疗心脏衰竭的药剂的方法
公开(公告)号：US20130345130A1
公开(公告)日：2013-12-26
申请号：US13636500
申请日：2011-03-10
申请人： Woo Jin Park , Pyoung Oh Yoon , Dong Kwon Yang
发明人： Woo Jin Park , Pyoung Oh Yoon , Dong Kwon Yang
IPC分类号： A61K38/18 , A61K31/7088 , A61K38/17
CPC分类号： A61K38/18 , A01K67/0275 , A61K31/7088 , A61K38/179 , C07K14/475 , C12N2799/022 , G01N33/6893 , G01N2800/325
摘要： The present invention relates to a pharmaceutical composition for preventing or treating a heart failure and a method for screening a therapeutic agent for preventing or treating a heart failure. The pharmaceutical composition of the present disclosure comprises the CCN5 or CCN2ΔCT protein, or a genetic carrier comprising a nucleotide sequence encoding the CCN5 or the CCN2ΔCT protein, exhibiting dramatic prevention or treatment efficacies on a heart failure even without surgical treatments accompanied with transplanting a donor heart.
摘要翻译：本发明涉及用于预防或治疗心力衰竭的药物组合物和筛选用于预防或治疗心力衰竭的治疗剂的方法。本公开的药物组合物包含CCN5或CCN2DeltaCT蛋白，或包含编码CCN5或CCN2DeltaCT蛋白的核苷酸序列的遗传载体，即使没有伴随移植供体心脏的外科手术，对心力衰竭也表现出显着的预防或治疗功效。

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