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1. 发明申请

US20100267817A1 LYOPHILIZED PHARMACEUTICAL COMPOSITION WITH IMPROVED RECONSTITUTION TIME CONTAINING TAXANE DERIVATIVES AND METHOD OF MANUFACTURING THE SAME 审中-公开
标题翻译：具有改进的包含TAXANE衍生物的重新构建时间的LYOPHILIZED药物组合物及其制备方法
公开(公告)号：US20100267817A1
公开(公告)日：2010-10-21
申请号：US12744151
申请日：2008-11-21
申请人： Woo Jae Jang , Joon-Gyo Oh , Young Youn Hwang , Won Jae Choi , Key An Um
发明人： Woo Jae Jang , Joon-Gyo Oh , Young Youn Hwang , Won Jae Choi , Key An Um
IPC分类号： A61K31/337 , A61P43/00
CPC分类号： A61K9/19 , A61K47/26 , A61K47/32
摘要： The present invention relates to a lyophilized composition with an improved reconstitution time comprising a taxoid and a method thereof. More specifically, the present invention relates to a lyophilized composition with an improved reconstitution time prepared by mixing and dissolving a taxoid; cyclodextrin (CD); a hydrophilic polymer selected from the group consisting of hydroxypropylmethyl CeIIuIoSe (HPMC), polyethylene glycol (PEG), and polyvinylpyrrolidone (PVP); and a bulking agent of saccharides in water for injection; and lyophilizing the mixture, and a method thereof.
摘要翻译：本发明涉及具有改进的重构时间的冻干组合物，其包含紫杉烷及其方法。更具体地，本发明涉及通过混合和溶解紫杉烷制备的具有改进的重构时间的冻干组合物; 环糊精（CD）; 选自羟丙基甲基CeIIuIoSe（HPMC），聚乙二醇（PEG）和聚乙烯吡咯烷酮（PVP）的亲水性聚合物; 和糖类在注射用水中的填充剂; 并将混合物冻干，及其方法。

2. 发明授权

US09155715B2 Transdermal composition comprising tolterodine 有权
标题翻译：包含托特罗定的透皮组合物
公开(公告)号：US09155715B2
公开(公告)日：2015-10-13
申请号：US13381328
申请日：2010-05-27
申请人： Yong Youn Hwang , Won Jae Choi , Yeo-Jin Park , Joon-gyo Oh
发明人： Yong Youn Hwang , Won Jae Choi , Yeo-Jin Park , Joon-gyo Oh
IPC分类号： C07C211/00 , A61L15/16 , A61K31/137 , A61K9/06 , A61K9/70 , A61K47/12 , A61K47/18 , A61K47/20 , A61K47/38
CPC分类号： A61K31/137 , A61K9/06 , A61K9/7061 , A61K47/12 , A61K47/183 , A61K47/20 , A61K47/38
摘要： A transdermal composition comprising tolterodine having improved storage stability is disclosed. The transdermal composition comprising tolterodine contains an antioxidant to stabilize tolterodine and can be stored for a long period of time.
摘要翻译：公开了包含具有改善的储存稳定性的托特罗定的透皮组合物。包含托特罗定的透皮组合物含有抗氧化剂以稳定托特罗定并且可以长期储存。

3. 发明申请

US20120123162A1 TRANSDERMAL COMPOSITION COMPRISING TOLTERODINE 有权
标题翻译：包含托乐定的超耐热组合物
公开(公告)号：US20120123162A1
公开(公告)日：2012-05-17
申请号：US13381328
申请日：2010-05-27
申请人： Yong Youn Hwang , Won Jae Choi , Yeo Jin Park , Joon-gyo Oh
发明人： Yong Youn Hwang , Won Jae Choi , Yeo Jin Park , Joon-gyo Oh
IPC分类号： C07C211/26
CPC分类号： A61K31/137 , A61K9/06 , A61K9/7061 , A61K47/12 , A61K47/183 , A61K47/20 , A61K47/38
摘要： A transdermal composition comprising tolterodine having improved storage stability is disclosed. The transdermal composition comprising tolterodine contains an antioxidant to stabilize tolterodine and can be stored for a long period of time.
摘要翻译：公开了包含具有改善的储存稳定性的托特罗定的透皮组合物。包含托特罗定的透皮组合物含有抗氧化剂以稳定托特罗定并且可以长期储存。

4. 发明授权

US07481071B2 Cooling/heating apparatus using cogeneration system 有权
标题翻译：使用热电联产系统的冷却/加热装置
公开(公告)号：US07481071B2
公开(公告)日：2009-01-27
申请号：US11298518
申请日：2005-12-12
申请人： Chang Min Choi , Seung Tak Kang , Won Jae Choi , Hyung Soo Lim , Yoon Jei Hwang
发明人： Chang Min Choi , Seung Tak Kang , Won Jae Choi , Hyung Soo Lim , Yoon Jei Hwang
IPC分类号： F25B27/02
CPC分类号： F25B13/00 , F25B27/02 , F25B2313/008 , F25B2700/21152 , Y02A30/274 , Y02E20/14
摘要： A cooling/heating apparatus using a cogeneration system is disclosed. The cooling/heating apparatus includes a discharge-side refrigerant heating unit which supplies heat of exhaust gas generated from an engine to a discharge-side refrigerant line connected to a compressor included in a cooling/heating unit, a suction-side refrigerant heating unit which supplies heat of cooling water used to cool the engine and the heat of the exhaust gas to a suction-side refrigerant line connected to the compressor, a discharge-side refrigerant temperature sensor which senses a temperature of a refrigerant passing through the discharge-side refrigerant line, and a bypass unit which bypasses the exhaust gas heat supplied to the discharge-side refrigerant line via the discharge-side refrigerant heating unit when the refrigerant temperature sensed by the discharge-side refrigerant temperature sensor is not lower than a predetermined temperature, to cut off the supply of the exhaust gas heat or to adjust an amount of the supplied exhaust gas heat. The exhaust gas heat and cooling water heat are appropriately distributed to both the suction and discharge sides of the compressor, so that it is possible to achieve an enhancement in heating performance and an enhancement in system efficiency.
摘要翻译：公开了一种使用热电联产系统的冷却/加热装置。冷却/加热装置包括：排出侧制冷剂加热单元，其将从发动机产生的排气的热量提供给与包括在冷却/加热单元中的压缩机连接的排出侧制冷剂管线;吸入侧制冷剂加热单元，将用于将发动机冷却的冷却水和排气的热量供给到与压缩机连接的吸入侧制冷剂管路的排出侧制冷剂温度传感器，其检测通过排出侧制冷剂的制冷剂的温度并且当由排出侧制冷剂温度传感器感测到的制冷剂温度不低于预定温度时，绕过通过排出侧制冷剂加热单元供应到排出侧制冷剂管线的废气热量的旁路单元，切断废气供给的热量，或者调节供给废气的热量。排气热和冷却水的热量适当地分配到压缩机的吸入侧和排出侧，从而可以实现加热性能的提高和系统效率的提高。

5. 发明授权

US07145258B2 Electricity generating and air conditioning system 失效
标题翻译：发电和空调系统
公开(公告)号：US07145258B2
公开(公告)日：2006-12-05
申请号：US11037071
申请日：2005-01-19
申请人： Seung Tak Kang , Chang Min Choi , Won Jae Choi , Hyung Soo Lim , Yoon Jei Hwang
发明人： Seung Tak Kang , Chang Min Choi , Won Jae Choi , Hyung Soo Lim , Yoon Jei Hwang
IPC分类号： F25B27/00
CPC分类号： F25B27/02 , F02G5/02 , Y02A30/274 , Y02B30/52 , Y02P80/152 , Y02T10/166
摘要： An electricity generating and air conditioning system including an engine, a generator connected to an output shaft of the engine to generate electricity, an air conditioner, which uses the electricity generated from the generator and includes a compressor, an indoor heat exchanger, an outdoor heat exchanger, and an expansion device, and an exhaust gas waste heat recovering device to recover heat of exhaust gas discharged from the engine and to transfer the recovered heat to a refrigerant passing through a discharge line of the compressor. The electricity generating and air conditioning system has an advantage in that an enhancement in heating performance is achieved.
摘要翻译：一种发电和空调系统，包括发动机，连接到发动机的输出轴以发电的发电机，使用发电机产生的电力的空调器，包括压缩机，室内热交换器，室外热量交换器和膨胀装置，以及废气废热回收装置，用于回收从发动机排出的排气的热量，并将回收的热量传递到通过压缩机的排出管路的制冷剂。发电和空调系统具有实现加热性能提高的优点。

6. 发明申请

US20080088147A1 Luggage floor box of a vehicle 审中-公开
标题翻译：车辆行李箱
公开(公告)号：US20080088147A1
公开(公告)日：2008-04-17
申请号：US11606200
申请日：2006-11-28
申请人： Won Jae Choi
发明人： Won Jae Choi
IPC分类号： B60N2/02
CPC分类号： B60R5/04
摘要： The present invention relates to a luggage floor box. A luggage floor box of a vehicle including: a receiving part which is formed by being downwardly indented at a rear side of a floor panel so as to provide a receiving space; and at least one partition disposed within the receiving part in a lengthwise direction thereof so as to divide the receiving space into a plurality of receiving spaces. The receiving part is configured to house a center seat of the last row which is mounted on the floor panel.
摘要翻译：本发明涉及行李箱地板箱。一种车辆的行李箱底盘，包括：接收部，其通过向下凹入在地板面板的后侧形成，以提供接收空间; 以及至少一个分隔件，其设置在所述容纳部件的长度方向上，以将所述容纳空间分割成多个容纳空间。接收部分构造成容纳安装在地板上的最后一排的中心座。

7. 发明授权

US07243504B2 Cogeneration system 失效
标题翻译：热电联产系统
公开(公告)号：US07243504B2
公开(公告)日：2007-07-17
申请号：US11046756
申请日：2005-02-01
申请人： Seung Tak Kang , Chang Min Choi , Won Jae Choi , Hyung Soo Lim , Yoon Jei Hwang
发明人： Seung Tak Kang , Chang Min Choi , Won Jae Choi , Hyung Soo Lim , Yoon Jei Hwang
IPC分类号： F25B27/02
CPC分类号： F25B27/02 , F25B13/00 , F25B30/06 , F25B2313/02523 , F25B2400/075 , F25B2500/02 , F25B2700/2106 , Y02A30/274 , Y02E20/14 , Y02P80/15
摘要： A cogeneration system including an engine, which drives a generator to generate electricity, a cooling/heating unit using a heat pump type refrigerant cycle, in which a refrigerant is circulated through at least one compressor, a four-way valve, a first outdoor heat exchanger, a first expansion device, and an indoor heat exchanger, in this order, during a cooling operation of the cogeneration system, and a waste heat consuming heating unit using a refrigerant cycle, in which the refrigerant is circulated through the compressor, the four-way valve, the indoor heat exchanger, a second expansion device, and a second outdoor heat exchanger to be heated by waste heat of the engine, in this order, during a heating operation of the cogeneration system. In accordance with the cogeneration system, it is possible to maximize utilization of engine waste heat during the heating operation and to achieve an enhancement in heating performance.
摘要翻译：一种热电联产系统，包括驱动发电机发电的发动机，使用热泵式制冷剂循环的冷却/加热单元，其中制冷剂通过至少一个压缩机循环，四通阀，第一室外热交换器，第一膨胀装置和室内热交换器，在制热系统的冷却运行期间，以及使用制冷剂循环的制冷剂循环的废热消耗加热单元，其中制冷剂循环通过压缩机，四所述室内热交换器，第二膨胀装置以及第二室外热交换器，在所述热电联供系统的加热运转中，按照所述发动机的余热进行加热。根据热电联产系统，可以最大限度地利用发热体在制热运转时的余热，实现加热性能的提高。

8. 发明授权

US09464642B2 Soft robotic actuators 有权
标题翻译：软机器人执行器
公开(公告)号：US09464642B2
公开(公告)日：2016-10-11
申请号：US13885967
申请日：2011-11-21
申请人： Filip Ilievski , Xin Chen , Aaron D. Mazzeo , George M. Whitesides , Robert F. Shepherd , Ramses V. Martinez , Won Jae Choi , Sen W. Kwok , Stephen Morin , Adam Stokes , Zhihong Nie
发明人： Filip Ilievski , Xin Chen , Aaron D. Mazzeo , George M. Whitesides , Robert F. Shepherd , Ramses V. Martinez , Won Jae Choi , Sen W. Kwok , Stephen Morin , Adam Stokes , Zhihong Nie
IPC分类号： F15B7/06 , B25J9/10 , B25J9/14 , F15B15/10 , B25J11/00
CPC分类号： F15B15/10 , B25J9/1075 , B25J9/142 , B25J11/00 , F15B7/06
摘要： A soft robotic device includes a flexible body having a width, a length and a thickness, wherein the thickness is at least 1 mm, the flexible body having at least one channel disposed within the flexible body, the channel defined by upper, lower and side walls, wherein at least one wall is strain limiting; and a pressurizing inlet in fluid communication with the at least one channel, the at least one channel positioned and arranged such that the wall opposite the strain limiting wall preferentially expands when the soft robotic device is pressurized through the inlet.
摘要翻译：软机器人装置包括具有宽度，长度和厚度的柔性体，其中所述厚度为至少1mm，所述柔性体具有设置在所述柔性体内的至少一个通道，所述通道由上，下和侧限定壁，其中至少一个壁是应变限制; 以及与所述至少一个通道流体连通的加压入口，所述至少一个通道定位和布置成使得当所述软自动装置通过所述入口被加压时，与所述应变限制壁相对的壁优先地膨胀。

9. 发明授权

US08367726B2 Acid salt of tolterodine having effective stability for transdermal drug delivery system 有权
标题翻译：托特罗定酸盐对透皮药物递送系统具有有效的稳定性
公开(公告)号：US08367726B2
公开(公告)日：2013-02-05
申请号：US12918753
申请日：2009-02-20
申请人： Yong Youn Hwang , Nam Ho Kim , Won Jae Choi , Yong Han Kim
发明人： Yong Youn Hwang , Nam Ho Kim , Won Jae Choi , Yong Han Kim
IPC分类号： A01N37/30 , A61K31/205
CPC分类号： C07C215/54 , C07C55/14 , C07C65/05 , C07C233/83 , C07C309/29 , C07C309/31 , C07C309/35 , C07D207/28
摘要： The present invention relates to an acid salt of tolterodine with superior stabililty and useful as a transdermal drug delivery system. More specifically, the present invention relates to a novel acid salt of tolterodine with superior stabililty to the conventional acid salts of tolterodine, which is useful as a pharmaceutical composition for the treatment of overactive bladder and can be formulated into a transdermal drug delivery system.
摘要翻译：本发明涉及具有优异稳定性的托特罗定的酸性盐，并且可用作透皮药物递送系统。更具体地说，本发明涉及一种与常规的托特罗定酸性盐具有优异稳定性的托特罗定的新型酸盐，其可用作治疗膀胱过度活动症的药物组合物，并可配制成透皮药物递送系统。

10. 发明申请

US20100331552A1 ACID SALT OF TOLTERODINE HAVING EFFECTIVE STABILITY FOR TRANSDERMAL DRUG DELIVERY SYSTEM 有权
标题翻译：含有有效稳定性的转铁药输送系统
公开(公告)号：US20100331552A1
公开(公告)日：2010-12-30
申请号：US12918753
申请日：2009-02-20
申请人： Yong Youn Hwang , Nam Ho Kim , Won Jae Choi , Yong Han Kim
发明人： Yong Youn Hwang , Nam Ho Kim , Won Jae Choi , Yong Han Kim
IPC分类号： C07D207/28 , C07C229/14 , C07C55/14 , C07C65/05 , C07C309/29 , C07C63/08 , C07C59/06 , C07C61/35
CPC分类号： C07C215/54 , C07C55/14 , C07C65/05 , C07C233/83 , C07C309/29 , C07C309/31 , C07C309/35 , C07D207/28
摘要： The present invention relates to an acid salt of tolterodine with superior stabililty and useful as a transdermal drug delivery system. More specifically, the present invention relates to a novel acid salt of tolterodine with superior stabililty to the conventional acid salts of tolterodine, which is useful as a pharmaceutical composition for the treatment of overactive bladder and can be formulated into a transdermal drug delivery system.
摘要翻译：本发明涉及具有优异稳定性的托特罗定的酸性盐，并且可用作透皮药物递送系统。更具体地说，本发明涉及一种与常规的托特罗定酸性盐具有优异稳定性的托特罗定的新型酸盐，其可用作治疗膀胱过度活动症的药物组合物，并可配制成透皮药物递送系统。

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