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1. 发明申请

US20100114113A1 Occlusion Remover and Method 审中-公开
标题翻译：闭塞除药及方法
公开(公告)号：US20100114113A1
公开(公告)日：2010-05-06
申请号：US12647214
申请日：2009-12-24
申请人： William R. Dubrul , Richard Eustis Fulton, III
发明人： William R. Dubrul , Richard Eustis Fulton, III
IPC分类号： A61B17/22
CPC分类号： A61M25/104 , A61B6/502 , A61B10/02 , A61B10/0266 , A61B17/11 , A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12122 , A61B17/12172 , A61B17/22004 , A61B17/221 , A61B17/32056 , A61B17/3421 , A61B18/14 , A61B90/39 , A61B90/40 , A61B2017/00287 , A61B2017/00955 , A61B2017/1107 , A61B2017/1135 , A61B2017/1205 , A61B2017/22034 , A61B2017/22067 , A61B2017/22079 , A61B2017/2212 , A61B2017/2215 , A61B2018/1407 , A61B2090/3904 , A61B2090/3908 , A61B2090/3962 , A61M25/0119
摘要： An occlusion may be removed from a graft or other body passageway using occlusion removing apparatus, comprising a catheter having a lumen through which an elongated occlusion engaging element can pass and a blocking mechanism at the open distal end thereof. The catheter is inserted into the body passageway with the blocking mechanism radially compressed during insertion. The blocking mechanism is radially expanded to near to the wall of the body passageway after insertion. After radially expanding the blocking mechanism, the occlusion engaging element is advanced into the occlusion. The expanded state of the blocking mechanism is used for blocking proximal passage of occlusion material around the outside of the catheter. Occlusion material may be moved proximally through the open end and into the lumen. The distal end of the occlusion engaging element may have an engagement mechanism, such as a balloon.
摘要翻译：可以使用阻塞去除装置从移植物或其他身体通道移除闭塞，该装置包括具有内腔的导管，细长的咬合接合元件可以通过该内腔和在其开放的远端处的阻塞机构。导管插入身体通道中，阻塞机构在插入过程中径向压缩。插入后，阻挡机构径向膨胀到靠近身体通道的壁。在径向膨胀阻塞机构之后，阻塞接合元件前进到闭塞中。阻塞机构的膨胀状态用于阻挡围绕导管外侧的闭塞物质的近端通道。闭塞材料可以向近侧移动通过开口端并进入内腔。咬合接合元件的远端可以具有诸如气囊的接合机构。

2. 发明授权

US06325816B1 Target tissue localization method 有权
标题翻译：目标组织定位方法
公开(公告)号：US06325816B1
公开(公告)日：2001-12-04
申请号：US09677952
申请日：2000-10-02
申请人： Richard Eustis Fulton, III , William R. Dubrul
发明人： Richard Eustis Fulton, III , William R. Dubrul
IPC分类号： A61M2900
CPC分类号： A61M25/04 , A61B90/39 , A61B2090/3908
摘要： A target tissue localization device (28) has outer and inner members (30, 32) which are longitudinally movable relative to one another. An anchor (42) is secured to the outer and inner members and is movable from a radially-contracted configuration to a radially-expanded configuration. The anchor may be a tubular mesh anchor. The anchor may have a sufficiently large cross-sectional area when in the radially-expanded configuration to substantially eliminate inadvertent dislodgment of the anchor once radially-expanded. In use, the location of the target tissue (56) is determined and the distal end of the localization device is passed through the patient's skin (58) and to the target tissue to create a tissue track (60) between the patient's skin and the target tissue. The target tissue includes near and far sides (62, 64). The anchor element, located at the target tissue is expanded to an expanded configuration. The method the anchor element may be located on the far side of the target tissue. The localization device may be selected with an anchor which is palpable for relocation of the target tissue.
摘要翻译：目标组织定位装置（28）具有能够相对于彼此纵向移动的外部构件（30）和内部构件（32）。锚固件（42）固定到外部构件和内部构件，并且可以从径向缩小构造移动到径向扩张构型。锚可以是管状网锚。当处于径向展开的构型中时，锚具可以具有足够大的横截面面积，以基本上消除锚固件一旦径向膨胀的无意中的移动。在使用中，确定目标组织（56）的位置，并且定位装置的远端通过患者的皮肤（58）和目标组织，以在患者的皮肤和患者的皮肤之间产生组织轨迹（60）目标组织。目标组织包括近侧和远侧（62,64）。位于目标组织的锚定元件被扩展到扩展构型。锚定元件可以位于目标组织的远侧上的方法。定位装置可以用可触及目标组织重新定位的锚点来选择。

3. 发明申请

US20100030256A1 Medical Devices and Methods 审中-公开
标题翻译：医疗器械与方法
公开(公告)号：US20100030256A1
公开(公告)日：2010-02-04
申请号：US12477371
申请日：2009-06-03
申请人： William R. Dubrul , Richard Eustis Fulton, III
发明人： William R. Dubrul , Richard Eustis Fulton, III
IPC分类号： A61B17/221 , A61M29/00
CPC分类号： A61M25/104 , A61B6/502 , A61B10/02 , A61B10/0266 , A61B17/11 , A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12122 , A61B17/12172 , A61B17/22004 , A61B17/221 , A61B17/32056 , A61B17/3421 , A61B18/14 , A61B90/39 , A61B90/40 , A61B2017/00287 , A61B2017/00955 , A61B2017/1107 , A61B2017/1135 , A61B2017/1205 , A61B2017/22034 , A61B2017/22067 , A61B2017/22079 , A61B2017/2212 , A61B2017/2215 , A61B2018/1407 , A61B2090/3904 , A61B2090/3908 , A61B2090/3962 , A61M25/0119
摘要： Medical devices include a catheter, a catheter/dilator assembly, an occluder, a rapid exchange dilator assembly, a funnel catheter, an anastomotic medical device, and associated methods.
摘要翻译：医疗装置包括导管，导管/扩张器组件，闭塞器，快速交换扩张器组件，漏斗导管，吻合医疗装置和相关方法。

4. 发明授权

US07479152B2 Target tissue localization device 失效
标题翻译：靶组织定位装置
公开(公告)号：US07479152B2
公开(公告)日：2009-01-20
申请号：US10885910
申请日：2004-07-06
申请人： Richard Eustis Fulton, III , William R. Dubrul
发明人： Richard Eustis Fulton, III , William R. Dubrul
IPC分类号： A61M29/00
CPC分类号： A61M25/04 , A61B90/39 , A61B2090/3908
摘要： A target tissue localization device includes a tubular mesh anchor element that is secured to a placement device. In use, the localization device is passed through the patient's skin to the target tissue, creating a tissue track. The tubular mesh anchor element is located at the target tissue and expanded from a contracted to an expanded configuration. Methods for localizing a lymph node are also described. After determining the position of the lymph node, a localization device, which includes an anchor element, is localized near or within the lymph node. The anchor element is then expanded.
摘要翻译：目标组织定位装置包括固定到放置装置的管状网状锚定元件。在使用中，定位装置通过患者的皮肤传递到目标组织，形成组织轨道。管状网状锚定元件位于目标组织处并且从收缩状态扩展到扩张构型。还描述了用于定位淋巴结的方法。在确定淋巴结的位置之后，包括锚定元件的定位装置位于淋巴结附近或内部。然后锚定元素被扩展。

5. 发明授权

US06758855B2 Target tissue localization device 有权
标题翻译：靶组织定位装置
公开(公告)号：US06758855B2
公开(公告)日：2004-07-06
申请号：US10134802
申请日：2002-04-29
申请人： Richard Eustis Fulton, III , William R. Dubrul
发明人： Richard Eustis Fulton, III , William R. Dubrul
IPC分类号： A61M2900
CPC分类号： A61M25/04 , A61B90/39 , A61B2090/3908
摘要： A target tissue localization device (28) has outer and inner members (30, 32) which are longitudinally movable relative to one another. An anchor (42) is secured to the outer and inner members and is movable from a radially-contracted configuration to a radially-expanded configuration. The anchor may be a tubular mesh anchor. The anchor may have a sufficiently large cross-sectional area when in the radially-expanded configuration to substantially eliminate inadvertent dislodgment of the anchor once radially-expanded. In use, the location of the target tissue (56) is determined and the distal end of the localization device is passed through the patient's skin (58) and to the target tissue to create a tissue track (60) between the patient's skin and the target tissue. The target tissue includes near and far sides (62, 64). The anchor element, located at the target tissue is expanded to an expanded configuration. The method the anchor element may be located on the far side of the target tissue. The localization device may be selected with an anchor which is palpable for relocation of the target tissue.
摘要翻译：目标组织定位装置（28）具有能够相对于彼此纵向移动的外部构件（30）和内部构件（32）。锚固件（42）固定到外部构件和内部构件，并且可以从径向缩小构造移动到径向扩张构型。锚可以是管状网锚。当处于径向展开的构型中时，锚具可以具有足够大的横截面面积，以基本上消除锚固件一旦径向膨胀的无意中的移动。在使用中，确定目标组织（56）的位置，并且定位装置的远端通过患者的皮肤（58）和目标组织，以在患者的皮肤和患者的皮肤之间产生组织轨迹（60）目标组织。目标组织包括近侧和远侧（62,64）。位于目标组织的锚定元件被扩展到扩展构型。锚定元件可以位于目标组织的远侧上的方法。定位装置可以用可触及目标组织重新定位的锚点来选择。

6. 发明申请

US20100036481A1 Cardiovascular Devices and Methods 审中-公开
标题翻译：心血管设备和方法
公开(公告)号：US20100036481A1
公开(公告)日：2010-02-11
申请号：US12479375
申请日：2009-06-05
申请人： William R. Dubrul , Richard Eustis Fulton, III
发明人： William R. Dubrul , Richard Eustis Fulton, III
IPC分类号： A61F2/06 , B05D3/10
CPC分类号： A61L29/16 , A61F2/90 , A61F2/958 , A61F2002/072 , A61F2250/0067 , A61L2300/416 , A61M25/10 , A61M29/02 , A61M2025/0057 , A61M2025/105 , A61M2025/1052 , A61M2025/1081 , A61N1/306 , A61N1/327
摘要： A material in a flowable state is applied to the interstitial pores of a radially-expandable endovascular tubular braid structure to modify the tubular braid structure for use in the treatment of cardiovascular disease. The material is cured to form a membrane at least within the coated interstitial pores. A cardiovascular device, for use in a vascular lumen within a body for treatment of cardiovascular disease, includes a braided body with electroporation means for helping prevent restenosis in a cardiovascular lumen. A method for treating cardiovascular disease includes placing a radially expandable and collapsible medical device within a cardiovascular passageway, positioning it at a target site, and placing it in a radially expanded state. Restenosis at the target site is inhibited by a chosen one of electroporation and iontophoresis. The medical device is collapsed and is then removed from the passageway.
摘要翻译：将可流动状态的材料施加到径向可扩张的血管内管状编织结构的间隙孔中，以改变用于治疗心血管疾病的管状编织结构。该材料被固化以至少在涂覆的间隙孔内形成膜。用于体内用于治疗心血管疾病的血管腔的心血管装置包括具有电穿孔装置的编织体，用于帮助预防心血管内腔中的再狭窄。用于治疗心血管疾病的方法包括将径向可膨胀和可折叠的医疗装置放置在心血管通路内，将其定位在靶位置，并将其放置在径向扩张状态。通过选择的电穿孔和离子电渗疗法抑制靶位点的再狭窄。医疗器械被塌缩，然后从通道中取出。

7. 发明授权

US06179860B2 Target tissue localization device and method 有权
标题翻译：靶组织定位装置及方法
公开(公告)号：US06179860B2
公开(公告)日：2001-01-30
申请号：US09376678
申请日：1999-08-18
申请人： Richard Eustis Fulton, III , William R. Dubrul
发明人： Richard Eustis Fulton, III , William R. Dubrul
IPC分类号： A61M2900
CPC分类号： A61M25/04 , A61B90/39 , A61B2090/3908
摘要： A target tissue localization device (28) has outer and inner members (30, 32) which are longitudinally movable relative to one another. An anchor (42) is secured to the outer and inner members and is movable from a radially-contracted configuration to a radially-expanded configuration. The anchor may be a tubular mesh anchor. The anchor may have a sufficiently large cross-sectional area when in the radially-expanded configuration to substantially eliminate inadvertent dislodgment of the anchor once radially-expanded. In use, the location of the target tissue (56) is determined and the distal end of the localization device is passed through the patient's skin (58) and to the target tissue to create a tissue track (60) between the patient's skin and the target tissue. The target tissue includes near and far sides (62, 64). The anchor element, located at the target tissue is expanded to an expanded configuration. The method the anchor element may be located on the far side of the target tissue. The localization device may be selected with an anchor which is palpable for relocation of the target tissue.
摘要翻译：目标组织定位装置（28）具有能够相对于彼此纵向移动的外部构件（30）和内部构件（32）。锚固件（42）固定到外部构件和内部构件，并且可以从径向缩小构造移动到径向扩张构型。锚可以是管状网锚。当处于径向展开的构型中时，锚具可以具有足够大的横截面面积，以基本上消除锚固件一旦径向膨胀的无意中的移动。在使用中，确定目标组织（56）的位置，并且定位装置的远端通过患者的皮肤（58）和目标组织，以在患者的皮肤和患者的皮肤之间产生组织轨迹（60）目标组织。目标组织包括近侧和远侧（62,64）。位于目标组织的锚定元件被扩展到扩展构型。锚定元件可以位于目标组织的远侧上的方法。定位装置可以用可触及目标组织重新定位的锚点来选择。

8. 发明授权

US06409742B1 Target tissue localization device and method 失效
标题翻译：靶组织定位装置及方法
公开(公告)号：US06409742B1
公开(公告)日：2002-06-25
申请号：US09678508
申请日：2000-10-02
申请人： Richard Eustis Fulton, III , William R. Dubrul
发明人： Richard Eustis Fulton, III , William R. Dubrul
IPC分类号： A61M2900
CPC分类号： A61M25/04 , A61B90/39 , A61B2090/3908
摘要： A target tissue localization device (28) has outer and inner members (30, 32) which are longitudinally movable relative to one another. An anchor (42) is secured to the outer and inner members and is movable from a radially-contracted configuration to a radially-expanded configuration. The anchor may be a tubular mesh anchor. The anchor may have a sufficiently large cross-sectional area when in the radially-expanded configuration to substantially eliminate inadvertent dislodgment of the anchor once radially-expanded. In use, the location of the target tissue (56) is determined and the distal end of the localization device is passed through the patient's skin (58) and to the target tissue to create a tissue track (60) between the patient's skin and the target tissue. The target tissue includes near and far sides (62, 64). The anchor element, located at the target tissue is expanded to an expanded configuration. The method the anchor element may be located on the far side of the target tissue. The localization device may be selected with an anchor which is palpable for relocation of the target tissue.
摘要翻译：目标组织定位装置（28）具有能够相对于彼此纵向移动的外部构件（30）和内部构件（32）。锚固件（42）固定到外部构件和内部构件，并且可以从径向缩小构型移动到径向扩张构型。锚可以是管状网锚。当处于径向展开的构型中时，锚具可以具有足够大的横截面面积，以基本上消除锚固件一旦径向膨胀的无意中的移动。在使用中，确定目标组织（56）的位置，并且定位装置的远端通过患者的皮肤（58）和目标组织，以在患者的皮肤和患者的皮肤之间产生组织轨迹（60）目标组织。目标组织包括近侧和远侧（62,64）。位于目标组织的锚定元件被扩展到扩展构型。锚定元件可以位于目标组织的远侧上的方法。定位装置可以用可触及目标组织重新定位的锚点来选择。

9. 发明授权

US07232432B2 Particle-removing medical device and method 有权
标题翻译：除粒医疗器械及方法
公开(公告)号：US07232432B2
公开(公告)日：2007-06-19
申请号：US11035581
申请日：2005-01-14
申请人： Richard E. Fulton, III , William R. Dubrul
发明人： Richard E. Fulton, III , William R. Dubrul
IPC分类号： A61M31/00 , A61M29/00 , A61M37/00
CPC分类号： A61M25/104 , A61F2/90 , A61F2/958 , A61F2250/0067 , A61L29/16 , A61L2300/416 , A61M25/10 , A61M25/1011 , A61M2025/0057 , A61M2025/1052 , A61M2025/1081 , A61N1/306 , A61N1/327
摘要： A particle-removing medical device includes an outer, hollow tube having a tube distal end and a porous braided structure having a distal part and a proximal part. Structure, housed within the tube and having a distal end positioned distally of the tube distal end, is used to move the braided structure from a contracted condition to an expanded condition by moving the distal ends of the tube and the structure towards one another. The braided structure is constructed to inhibit particles from moving completely through the braided structure when in the expanded condition.
摘要翻译：颗粒除去医疗装置包括具有管远端的外部中空管和具有远端部分和近端部分的多孔编织结构。结构，容纳在管内并且具有远离管远端的远端，用于通过将管的远端和结构朝向彼此移动而将编织结构从收缩状态移动到扩张状态。编织结构被构造成在膨胀状态下抑制颗粒完全移动通过编织结构。

10. 发明授权

US07150712B2 Target tissue localization assembly and method 有权
标题翻译：靶组织定位装配及方法
公开(公告)号：US07150712B2
公开(公告)日：2006-12-19
申请号：US10212467
申请日：2002-08-05
申请人： Eric L. Buehlmann , Robert J. Laird , William R. Dubrul
发明人： Eric L. Buehlmann , Robert J. Laird , William R. Dubrul
IPC分类号： A61B1/00
CPC分类号： A61B18/1492 , A61B17/221 , A61B18/148 , A61B90/02 , A61B90/39 , A61B2017/00867 , A61B2017/1205 , A61B2017/22061 , A61B2017/2212 , A61B2017/2215 , A61B2018/00214 , A61B2018/00601 , A61B2018/1475 , A61B2090/3908
摘要： A target tissue localization assembly includes a radially expandable tissue anchor connected to the distal ends of an anchor assembly and an elongated anchor actuator element. A lock, engageable between the actuator element and the placement element, may be used to prevent collapse of the anchor from its radially expanded state. A sheath may be slidably mounted over the anchor assembly. The sheath and the anchor assembly may be configured to permit the sheath to move in a proximal direction, relative to the anchor assembly, past a chosen location while preventing the sheath from moving past the chosen location in a distal direction.
摘要翻译：目标组织定位组件包括连接到锚固组件的远端的可径向扩张的组织锚固件和细长的锚定致动器元件。可以使用可在致动器元件和放置元件之间接合的锁，以防止锚从其径向膨胀状态的塌陷。护套可以可滑动地安装在锚固组件上。护套和锚固组件可以被配置为允许护套相对于锚固组件在近端方向上移动经过所选择的位置，同时防止护套沿远侧方向移动经过所选择的位置。

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