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1. 发明授权

US06695813B1 Embolic protection devices 有权
标题翻译：栓塞保护装置
公开(公告)号：US06695813B1
公开(公告)日：2004-02-24
申请号：US09476159
申请日：1999-12-30
申请人： William J. Boyle , David H. Burkett , Andy E. Denison , Benjamin C. Huter , Scott J. Huter , Arkady Kokish , Kent C. B. Stalker , Chicheng Wang , John D. Whitfield
发明人： William J. Boyle , David H. Burkett , Andy E. Denison , Benjamin C. Huter , Scott J. Huter , Arkady Kokish , Kent C. B. Stalker , Chicheng Wang , John D. Whitfield
IPC分类号： A61M2900
CPC分类号： A61F2/013 , A61F2002/011 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/005 , A61F2230/0067 , A61F2230/008
摘要： An embolic protection device includes a filtering assembly having a self-expanding strut assembly and a filter element. The filtering assembly can be attached to a guidewire and deployed within the patient's vasculature into an area of treatment. A restraining sheath maintains the filtering assembly in its collapsed position until it is ready to be deployed by the physician. Interventional devices can be delivered over the guidewire and any embolic debris created and released into the blood stream will enter the filtering assembly. The filtering assembly can be rotatably mounted on the guide wire and may include a dampening element which helps to prevent some shock force that may be transmitted along the guide to the deployed filtering assembly.
摘要翻译：栓塞保护装置包括具有自扩张支柱组件和过滤元件的过滤组件。过滤组件可以附接到导丝并且部署在患者的脉管系统内进入治疗区域。限制护套将过滤组件保持在其折叠位置，直到其准备好被医生部署为止。介入装置可以通过导线传送，并且产生并释放到血流中的任何栓塞碎片将进入过滤组件。过滤组件可以可旋转地安装在导丝上，并且可以包括阻尼元件，该阻尼元件有助于防止可能沿着引导件传递到部署的过滤组件的一些冲击力。

2. 发明授权

US08845583B2 Embolic protection devices 有权
标题翻译：栓塞保护装置
公开(公告)号：US08845583B2
公开(公告)日：2014-09-30
申请号：US11651667
申请日：2007-01-10
申请人： William J. Boyle , David H. Burkett , Andy E. Denison , Benjamin C. Huter , Scott J. Huter , Arkady Kokish , Kent C. B. Stalker , Chicheng Wang , John D. Whitfield
发明人： William J. Boyle , David H. Burkett , Andy E. Denison , Benjamin C. Huter , Scott J. Huter , Arkady Kokish , Kent C. B. Stalker , Chicheng Wang , John D. Whitfield
IPC分类号： A61M29/00 , A61F2/01
CPC分类号： A61F2/013 , A61F2002/011 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/005 , A61F2230/0067 , A61F2230/008
摘要： An embolic protection device for use in a blood vessel when an interventional procedure is being performed in a stenosed or occluded region to capture any embolic material which may be created and released into the bloodstream during the procedure. The device includes a filtering assembly having a self-expanding strut assembly and a filter element attached thereto. In one embodiment, the filtering assembly is attached to the distal end of a guidewire and is deployed within the patient's vasculature as the guidewire is manipulated into the area of treatment. A restraining sheath placed over the filtering assembly in a coaxial arrangement maintains the filtering assembly in its collapsed position until it is ready to be deployed by the physician. Thereafter, the sheath can be retracted to expose the filtering assembly which will then self-expand within the patient's vasculature. Interventional devices can be delivered over the guidewire and any embolic debris created during the interventional procedure and released into the blood stream will enter the filtering assembly and be captured therein. Other embodiments include filtering assemblies attached to an outer tubular member and inner shaft member which apply axial force to the distal ends of the assembly to either expand or contract the struts as needed.
摘要翻译：一种用于血管中的栓塞保护装置，当在狭窄或闭塞区域进行介入手术以捕获可能在手术期间产生和释放到血流中的任何栓塞物质。该装置包括具有自扩张支柱组件和附接到其上的过滤元件的过滤组件。在一个实施例中，过滤组件附接到导丝的远端，并且当导线被操纵进入治疗区域时，其部署在患者的脉管系统内。以同轴布置放置在过滤组件上方的限制护套将过滤组件保持在其收缩位置，直到其准备好由医师部署。此后，护套可缩回以露出过滤组件，然后过滤组件将在患者的脉管系统内自我扩张。介入装置可以在导丝上传送，并且在介入手术期间产生的并释放到血流中的任何栓塞碎片将进入过滤组件并被捕获在其中。其他实施例包括附接到外部管状构件和内部轴构件的过滤构件，其向组件的远端施加轴向力，以根据需要来扩展或收缩支柱。

3. 发明授权

US06761732B2 Catheter apparatus for treating occluded vessels and filtering embolic debris and method of use 有权
标题翻译：用于治疗闭塞血管和过滤栓塞性碎屑的导管装置及其使用方法
公开(公告)号：US06761732B2
公开(公告)日：2004-07-13
申请号：US10259920
申请日：2002-09-27
申请人： David H. Burkett , Arkady Kokish , Chicheng Wang
发明人： David H. Burkett , Arkady Kokish , Chicheng Wang
IPC分类号： A61F206
CPC分类号： A61F2/958 , A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/005 , A61F2230/008
摘要： A catheter apparatus includes a lesion dilating member disposable at a lesion position in a vessel (e.g. a patient's artery) which is dilatable to open the vessel at the lesion position. An emboli-capturing assembly having a perfusion member and filter is displaced downstream from the lesion dilating member to capture embolic debris released in the fluid flow. The perfusion member may illustratively have peaks and channels formed between adjacent peaks which cooperate with the filter to create trapping pockets that capture embolic debris. The filter may be made from any flexible and porous material with dimensions to pass the fluid and block the emboli. The perfusion member is thereafter deflated to provide for emboli retention in the perfusion member.
摘要翻译：导管装置包括在容器（例如患者的动脉）中的损伤位置处一次性的病变扩张构件，其可扩张以在病变位置打开血管。具有灌注构件和过滤器的栓塞捕获组件从病变扩张构件的下游位移，以捕获在流体流中释放的栓塞碎片。灌注构件可以示例性地具有在相邻峰之间形成的峰和通道，其与过滤器配合以产生捕获栓塞碎片的捕集袋。过滤器可以由具有尺寸的任何柔性和多孔材料制成以通过流体并阻塞栓塞。然后灌注构件放气以提供灌注构件中的栓塞保留。

4. 发明授权

US06511503B1 Catheter apparatus for treating occluded vessels and filtering embolic debris and method of use 有权
公开(公告)号：US06511503B1
公开(公告)日：2003-01-28
申请号：US09475106
申请日：1999-12-30
申请人： David H. Burkett , Arakady Kokish , Chicheng Wang
发明人： David H. Burkett , Arakady Kokish , Chicheng Wang
IPC分类号： A61F206
CPC分类号： A61F2/958 , A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/005 , A61F2230/008
摘要： A catheter apparatus includes a lesion dilating member disposable at a lesion position in a vessel (e.g. a patient's artery) which is dilatable to open the vessel at the lesion position. An emboli-capturing assembly having a perfusion member and filter is displaced downstream from the lesion dilating member to capture embolic debris released in the fluid flow. The perfusion member may illustratively have peaks and channels formed between adjacent peaks which cooperate with the filter to create trapping pockets that capture embolic debris. The filter may be made from any flexible and porous material with dimensions to pass the fluid and block the emboli. The perfusion member is thereafter deflated to provide for emboli retention in the perfusion member.

5. 发明申请

US20120065622A1 COLOR CODED GUIDE WIRE AND METHODS OF MAKING SAME 有权
标题翻译：彩色编码指南及其制作方法
公开(公告)号：US20120065622A1
公开(公告)日：2012-03-15
申请号：US12880465
申请日：2010-09-13
申请人： Wayne E. Cornish , Travis R. Yribarren , Carl P. Frick , Jessica M. Saenz , Emmanuel C. Biagtan , Pablito Buan , David H. Burkett , John J. Nelson, III , Robert J. Peralta , Michelle E. Alexander , Arthur R. Tyre , John A. Simpson
发明人： Wayne E. Cornish , Travis R. Yribarren , Carl P. Frick , Jessica M. Saenz , Emmanuel C. Biagtan , Pablito Buan , David H. Burkett , John J. Nelson, III , Robert J. Peralta , Michelle E. Alexander , Arthur R. Tyre , John A. Simpson
IPC分类号： A61M25/09 , B05D3/14 , B05D3/10
CPC分类号： A61M25/09 , A61M2025/0008 , A61M2025/09108 , A61M2025/09133 , Y10T29/49815 , Y10T29/49826 , Y10T29/49885 , Y10T156/10
摘要： A color coding is applied to medical guide wires by coloring portions of the guide wire to distinguish similar guide wires and guide wire portions from a particular manufacturer. The metallic elongate core can be colored using various methods such as electrochemical processes, sputtering, electroplating, and laser inducing microstructures to alter the surface characteristics of the elongate metallic core. Alternatively, the outer layer of the guide wire can be color coded by using non-standard colors or by introducing a colored band on the guide wire.
摘要翻译：通过着色引导线的部分来将医疗引导线上的颜色编码应用于将特定制造商的类似导丝和导丝部分区分开。金属细长芯可以使用诸如电化学工艺，溅射，电镀和激光诱导微结构的各种方法着色，以改变细长金属芯的表面特性。或者，引导线的外层可以通过使用非标准颜色进行颜色编码，或者通过在导丝上引入彩色带。

6. 发明申请

US20080146967A1 Polymer coated guidewire 有权
标题翻译：聚合物涂层导丝
公开(公告)号：US20080146967A1
公开(公告)日：2008-06-19
申请号：US10631275
申请日：2003-07-31
申请人： Mark T. Richardson , David M. Anderson , Emmanuel C. Biagtan , Lawrence E. Brennan , David H. Burkett , Wayne E. Cornish , Robert C. Esselstein , James Jacobs , Marc M. Jalisi , Daryush P. Mirzaee , Olin J. Palmer , John Schreiner , Kent C. Stalker
发明人： Mark T. Richardson , David M. Anderson , Emmanuel C. Biagtan , Lawrence E. Brennan , David H. Burkett , Wayne E. Cornish , Robert C. Esselstein , James Jacobs , Marc M. Jalisi , Daryush P. Mirzaee , Olin J. Palmer , John Schreiner , Kent C. Stalker
IPC分类号： A61M25/00
CPC分类号： A61L31/10 , A61L31/18 , A61M25/0045 , A61M25/0054 , A61M25/09 , A61M2025/09083 , A61M2025/09133 , A61M2025/09166
摘要： A guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal portion of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that is configured to produce a linear change in stiffness of the core over a longitudinal portion of the device. An embodiment has a plurality of radiopaque elements that may be intermittent, continuous or in the form of a helical ribbon for scaled measurement of intracorporeal structure under fluoroscopic imaging. Another embodiment has at least one layer of polymer over the distal end of the device.
摘要翻译：具有芯构件等的导丝或其一部分具有多个具有锥形角度的相邻锥形段的构造，以在该装置的纵向部分上产生线性的刚度变化。该装置还可以具有连续变化的锥角的芯部，以产生曲线轮廓，其被配置成在装置的纵向部分上产生芯的刚度的线性变化。一个实施例具有多个不透射线的元件，其可以是间断的，连续的或呈螺旋状的形式，用于在透视成像下对体内结构进行缩放测量。另一个实施方案在装置的远端上具有至少一层聚合物。

7. 发明授权

US06673025B1 Polymer coated guidewire 有权
标题翻译：聚合物涂层导丝
公开(公告)号：US06673025B1
公开(公告)日：2004-01-06
申请号：US09441698
申请日：1999-11-16
申请人： Mark T. Richardson , David M. Anderson , Emmanuel C. Biagtan , Lawrence E. Brennan , David H. Burkett , Wayne E. Cornish , Robert C. Esselstein , James Jacobs , Marc M. Jalisi , Daryush P. Mirzaee , Olin J. Palmer , John Schreiner , Kent C. Stalker
发明人： Mark T. Richardson , David M. Anderson , Emmanuel C. Biagtan , Lawrence E. Brennan , David H. Burkett , Wayne E. Cornish , Robert C. Esselstein , James Jacobs , Marc M. Jalisi , Daryush P. Mirzaee , Olin J. Palmer , John Schreiner , Kent C. Stalker
IPC分类号： A61B500
CPC分类号： A61M25/09 , A61M2025/09175
摘要： A guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal portion of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that is configured to produce a linear change in stiffness of the core over a longitudinal portion of the device. An embodiment has a plurality of radiopaque elements that may be intermittent, continuous or in the form of a helical ribbon for scaled measurement of intracorporeal structure under flouroscopic imaging. Another embodiment has at least one layer of polymer over the distal end of the device.
摘要翻译：具有芯构件等的导丝或其一部分具有多个具有锥形角度的相邻锥形段的构造，以在该装置的纵向部分上产生线性的刚度变化。该装置还可以具有连续变化的锥角的芯部，以产生曲线轮廓，其被配置成在装置的纵向部分上产生芯的刚度的线性变化。一个实施例具有多个不透射线的元件，其可以是间歇的，连续的或以螺旋带的形式，用于在荧光成像下对体内结构进行缩放测量。另一个实施方案在装置的远端上具有至少一层聚合物。

8. 发明授权

US06645159B1 Wire joint and method 有权
标题翻译：线接头和方法
公开(公告)号：US06645159B1
公开(公告)日：2003-11-11
申请号：US09452342
申请日：1999-11-30
申请人： David H. Burkett
发明人： David H. Burkett
IPC分类号： A61B500
CPC分类号： A61M25/09 , A61M2025/09083 , A61M2025/09108 , Y10T29/49208
摘要： A process for joining two discrete wire components without the need of a third component, wherein material from the end of one wire component is removed to form a female end and the end of the other wire is formed into a male end. The male may be secured within the female end by conventional means. The female end may be formed by electrical discharge machining or laser drilling.
摘要翻译：一种用于连接两个离散线材部件而不需要第三部件的方法，其中从一个丝线部件的端部去除材料以形成阴端，并且另一条线的端部形成为阳端。男性可以通过常规方式固定在女性终端内。阴端可以通过放电加工或激光钻孔形成。

9. 发明授权

US08613712B1 Textured polymer coated guide wire and method of manufacture 有权
标题翻译：纹理聚合物涂层导丝及其制造方法
公开(公告)号：US08613712B1
公开(公告)日：2013-12-24
申请号：US10664004
申请日：2003-09-16
申请人： David H. Burkett , Kevin Britton , Ryan Grandfield , Peter J. D'Aquanni , David Wrolstad , Edwin P. Mahieu , Wayne E. Cornish , Mark T. Richardson
发明人： David H. Burkett , Kevin Britton , Ryan Grandfield , Peter J. D'Aquanni , David Wrolstad , Edwin P. Mahieu , Wayne E. Cornish , Mark T. Richardson
IPC分类号： A61B5/00
CPC分类号： A61M25/09 , A61B17/12145 , A61F2/95 , A61F2/958 , A61M25/0043 , A61M2025/006 , A61M2025/0062 , A61M2025/09108 , A61M2025/09133 , B29C47/0014 , B29C47/003 , B29C47/026
摘要： A guide wire for advancing a medical device such as a catheter through a patient's body lumen which has an elongated core with proximal and distal core section, a flexible tubular member such as a coil on the distal end. The wire core includes surface textures that are translated into the overlying coating. Alternatively, the coating has its own surface texture. The surface textures include randomly or non-randomly spaced bumps, divots, ridges, helical grooves, longitudinal grooves, undulations, etc.
摘要翻译：一种用于使诸如导管的医疗装置通过患者体腔前进的导丝，所述导管具有具有近端和远侧芯部的细长芯，在远端上具有诸如线圈的柔性管状构件。线芯包括被翻译成上覆涂层的表面纹理。或者，涂层具有其自己的表面纹理。表面纹理包括随机或非随机间隔的凸块，凸纹，凸脊，螺旋槽，纵向凹槽，起伏等。

10. 发明授权

US07892251B1 Component for delivering and locking a medical device to a guide wire 有权
标题翻译：用于将医疗装置输送和锁定到导丝的部件
公开(公告)号：US07892251B1
公开(公告)日：2011-02-22
申请号：US10706295
申请日：2003-11-12
申请人： Brad Kellerman , David H. Burkett , Robert Hayzelden
发明人： Brad Kellerman , David H. Burkett , Robert Hayzelden
IPC分类号： A61M29/00
CPC分类号： A61M25/09 , A61M2025/09125
摘要： A locking component delivers and locks an attached medical device along a pre-deployed guide wire. The locking component can lock onto a flexible body member disposed on the guide wire, such as the distal helical tip coil of a conventional guide or a specially-designed guide wire. The locking component includes a tapered opening which temporarily compresses a portion of the helical coil and a locking recess in communication with the tapered opening for receiving the compressed coil. Compressed coils which enter the locking recess will spring back to their original shape (diameter) within the locking recess, locking the component to the coil.
摘要翻译：锁定部件沿着预先展开的导丝输送和锁定附接的医疗装置。锁定部件可以锁定在设置在导丝上的柔性主体部件上，例如常规导向件的远端螺旋尖端线圈或特别设计的导丝。锁定部件包括锥形开口，其临时压缩螺旋线圈的一部分和与用于接收压缩线圈的锥形开口连通的锁定凹槽。进入锁定凹槽的压缩线圈将弹回到锁定凹槽内的原始形状（直径），将部件锁定到线圈上。

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