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1. 发明申请

US20050155113A1 Vectors and methods for immunization against Norwalk virus using transgenic plants 有权
标题翻译：使用转基因植物免疫Norwalk病毒的载体和方法
公开(公告)号：US20050155113A1
公开(公告)日：2005-07-14
申请号：US10895791
申请日：2004-07-21
申请人： William Hamilton , Koen Hellendoorn , Timothy Jones , Dwayne Kirk , Hugh Mason , Xiuren Zhang , Charles Arntzen
发明人： William Hamilton , Koen Hellendoorn , Timothy Jones , Dwayne Kirk , Hugh Mason , Xiuren Zhang , Charles Arntzen
IPC分类号： A01H1/00 , A61K20060101 , A61K39/12 , C12N7/00 , C12N15/82 , C12Q1/70
CPC分类号： C12N15/8258 , A61K2039/5258 , A61K2039/542 , C07K14/005 , C12N2770/16022
摘要： The present invention relates to a synthetic plant-optimized nucleic acid molecule having a Norwalk virus capsid protein coding nucleotide sequence, and nucleic acid constructs, host cells, expression systems, and plants having the plant-optimized Norwalk virus nucleic acid molecule. The present invention also relates to a method of producing Norwalk virus capsid protein virus-like particles in a transgenic plant or transgenic plant seed transformed with a plant-optimized nucleic acid molecule encoding Norwalk virus capsid protein. The plant or a component thereof can be administered to a subject under conditions effective to immunize the subject against disease resulting from infection by a Norovirus, including Norwalk virus. An oral vaccine for immunization of a subject against Norwalk virus infection is also disclosed.
摘要翻译：本发明涉及具有Norwalk病毒衣壳蛋白编码核苷酸序列的合成植物优化核酸分子，以及具有植物优化诺瓦克病毒核酸分子的核酸构建体，宿主细胞，表达系统和植物。本发明还涉及在用植物优化的编码诺瓦克病毒衣壳蛋白的核酸分子转化的转基因植物或转基因植物种子中产生诺瓦克病毒衣壳蛋白病毒样颗粒的方法。植物或其组分可以在有效免疫受试者的病症下施用于受诺如病毒（包括诺瓦克病毒）感染引起的疾病的病症。还公开了用于免疫Norwalk病毒感染的受试者的口服疫苗。

2. 发明授权

US07184918B2 Automated system and method for conducting usability testing 有权
标题翻译：用于进行可用性测试的自动化系统和方法
公开(公告)号：US07184918B2
公开(公告)日：2007-02-27
申请号：US11095259
申请日：2005-03-31
申请人： William Hamilton , Donald Allen Dalton , Dean Craven
发明人： William Hamilton , Donald Allen Dalton , Dean Craven
IPC分类号： G06F19/00
CPC分类号： G09B7/02 , G06F9/451 , G06F11/3419 , G06F11/3438 , G06F11/3466 , G06F11/3476 , G06F2201/86
摘要： An automated system and method for conducting a usability test. The system conducts the usability test and records events that occur on the computer screen in sync with both the video and audio of the user and creates a complete chronicle of events that occur behind the scenes in the applications and the operating system. The system, depending upon the settings specified in the configuration, also captures other input streams and then saves the complete recording of the usability test, along with all the desired events and captures, in a file format. The system allows a remote viewer to observe, in real time, the recording of the usability test and to set markers at critical moments during the recording which are to be recorded. The system also allows the manager or administrator to configure the preferences, import and analyze the usability test and recording files, and prepare presentation videos of the usability test based upon the analyzed criteria.
摘要翻译：用于进行可用性测试的自动化系统和方法。系统进行可用性测试并记录计算机屏幕上发生的与用户的视频和音频同步的事件，并创建在应用程序和操作系统中的幕后事件的完整纪事。根据配置中指定的设置，系统还会捕获其他输入流，然后以文件格式保存可用性测试的完整记录以及所有所需的事件和捕获。该系统允许远程观察者实时观察可用性测试的记录，并在录制期间的关键时刻设置标记。该系统还允许管理员或管理员配置首选项，导入和分析可用性测试和记录文件，并根据分析的标准准备可用性测试的演示视频。

3. 发明申请

US20050274255A1 Adjustable ring positioner 审中-公开
标题翻译：可调式定位器
公开(公告)号：US20050274255A1
公开(公告)日：2005-12-15
申请号：US10866791
申请日：2004-06-15
申请人： William Hamilton
发明人： William Hamilton
IPC分类号： B25B27/12 , F15B15/26 , F16J9/00
CPC分类号： B25B27/12 , F16J9/00
摘要： A ring positioning device has positioning elements radially adjustable on a support to fit different diameter cylinder bores. The positioning elements slide in channels in the support and are clamped to the support by knobs that have threaded shafts that slide in slots through the support and are threaded into the positioning elements to clamp them to the support. The positioning elements have protrusions or shoulders that engage the cylinder block deck and lower abutment surfaces that position piston rings in the cylinder bore. A second embodiment uses pivoted arms to adjust for different cylinder bore size with threaded rods on the arms to adjust for different depth ring placement.
摘要翻译：环形定位装置具有可在支撑件上径向调节以适应不同直径的气缸孔的定位元件。定位元件在支撑件中的通道中滑动，并通过具有螺纹轴的旋钮夹紧到支撑件上，该螺纹轴通过支撑件滑入槽中，并且被拧入定位元件中以将其夹紧到支撑件上。定位元件具有接合气缸体座面的凸起或肩部，以及将活塞环定位在气缸孔中的下邻接表面。第二实施例使用枢转臂来调节不同的气缸孔尺寸，其中在杆上的螺杆被调节以适应不同的深度环安置。

4. 发明授权

US5545820A Insect control using lectins having specific mannose-binding ability 失效
标题翻译：使用具有特异性甘露糖结合能力的凝集素进行昆虫控制
公开(公告)号：US5545820A
公开(公告)日：1996-08-13
申请号：US425315
申请日：1995-04-17
申请人： Angharad Gatehouse , Vaughan Hilder , Els Van Damme , Willy Peumans , Christine Newell , William Hamilton
发明人： Angharad Gatehouse , Vaughan Hilder , Els Van Damme , Willy Peumans , Christine Newell , William Hamilton
IPC分类号： A01H5/00 , A01H1/00 , A01N65/40 , C07K14/00 , C07K14/415 , C07K14/42 , C12N5/10 , C12N15/09 , C12N15/82 , C12P21/02 , A01C1/06 , A01N25/26 , C07H21/04 , C12N15/29
CPC分类号： C12N15/8286 , A01H1/00 , A01N65/40 , C07K14/42
摘要： The invention relates to the use of lectins having specific mannose-binding ability and/or derived from Amaryllidaceae or Alliaceae for the control of insect pests. Transgenic plants containing and capable of expressing foreign genes coding for such lectins are also disclosed.
摘要翻译：本发明涉及具有特异性甘露糖结合能力和/或衍生自芳樟科或i科的凝集素用于防治害虫的用途。还公开了含有能够表达编码这种凝集素的外源基因的转基因植物。

5. 发明授权

US4665593A Clamp for elongate members 失效
标题翻译：夹紧细长件
公开(公告)号：US4665593A
公开(公告)日：1987-05-19
申请号：US777822
申请日：1985-09-19
申请人： Colin M. Davies , William Hamilton
发明人： Colin M. Davies , William Hamilton
IPC分类号： F16B2/06 , E21D11/22 , F16B7/04 , A44B21/00
CPC分类号： E21D11/22 , Y10T24/44017 , Y10T24/44034
摘要： A clamp for joining together overlapping sections of elongate members in, for example, telescopic steel arches used in the mining industry comprises a frontal plate and a U-bolt, the arms of the U-bolt being inclined to a line drawn normal to a load bearing surface of the frontal plate at a preferred angle of between 5.degree. and 40.degree..
摘要翻译：用于连接在例如采矿业中使用的伸缩钢拱的细长构件的重叠部分的夹具包括前板和U形螺栓，U形螺栓的臂倾斜到垂直于负载拉出的线前板的轴承表面以5°至40°之间的优选角度。

6. 发明申请

US20070043506A1 System for and method of determining a host vehicle lane change 有权
标题翻译：确定主车道变化的系统和方法
公开(公告)号：US20070043506A1
公开(公告)日：2007-02-22
申请号：US11436497
申请日：2006-05-18
申请人： Upali Mudalige , William Hamilton
发明人： Upali Mudalige , William Hamilton
IPC分类号： G01C21/00 , G08G1/16
CPC分类号： B60T7/22 , G01C21/00 , G08G1/163
摘要： A tracking system adapted for use with communicatively coupled traveling host and remote vehicles, includes a locator device configured to determine sets of current position, and trail coordinates for each of the vehicles. The preferred system further includes sensors operable to determine a condition value for each vehicle at each of said set of coordinates, and a controller configured to determine a congruent path between the vehicles, and a congruent path divergence by the host vehicle, and cause the transmission of an alert of the divergence from the host vehicle to the remote vehicle using vehicle-to-vehicle communication.
摘要翻译：适于与通信耦合的行进主机和远程车辆一起使用的跟踪系统包括配置成确定当前位置的集合的定位装置以及每个车辆的跟踪坐标。优选系统还包括可操作以在所述坐标系中的每一个确定每个车辆的状况值的传感器，以及被配置为确定车辆之间的一致路径的控制器和由本车辆发生的一致的路径发散，使用车对车通信来警告从主车辆到远程车辆的分歧。

7. 发明申请

US20070001830A1 Vehicle speed monitoring system 有权
标题翻译：车速监控系统
公开(公告)号：US20070001830A1
公开(公告)日：2007-01-04
申请号：US11171509
申请日：2005-06-30
申请人： Oguz Dagci , Donald Grimm , Varsha Sadekar , Daniel Bartz , Sarmad Hermiz , William Hamilton
发明人： Oguz Dagci , Donald Grimm , Varsha Sadekar , Daniel Bartz , Sarmad Hermiz , William Hamilton
IPC分类号： B60Q1/00
CPC分类号： G01P1/103 , B60K31/185 , B60W2550/22
摘要： A method for monitoring vehicle speed is provided. The method includes receiving a current speed of a vehicle and a current speed limit associated with a current location of the vehicle. A current speed range is calculated by comparing the current speed of the vehicle to the current speed limit. Operator alert preferences including a caution range and a warning range are accessed. An alert responsive to the current speed range and to the operator alert preferences is communicated to the operator of the vehicle. The alert includes one or more caution attributes when the current speed range of the vehicle is within the caution range. The alert includes one or more warning attributes when the current speed range of the vehicle is within the warning range. The alert includes one or more at speed attributes when the current speed range of the vehicle is not within the caution range or the warning range.
摘要翻译：提供了一种监视车速的方法。该方法包括接收车辆的当前速度和与车辆的当前位置相关联的当前速度限制。通过将车辆的当前速度与当前速度限制进行比较来计算当前速度范围。可以访问包括警告范围和警告范围的操作员警报首选项。响应于当前速度范围和操作员警报偏好的警报被传达给车辆的操作者。当车辆的当前速度范围在警告范围内时，警报包括一个或多个警告属性。当车辆的当前速度范围在警告范围内时，警报包括一个或多个警告属性。当车辆的当前速度范围不在警告范围或警告范围内时，警报包括一个或多个速度属性。

8. 发明申请

US20050254775A1 Automated system and method for conducting usability testing 有权
标题翻译：用于进行可用性测试的自动化系统和方法
公开(公告)号：US20050254775A1
公开(公告)日：2005-11-17
申请号：US11095259
申请日：2005-03-31
申请人： William Hamilton , Donald Dalton , Dean Craven
发明人： William Hamilton , Donald Dalton , Dean Craven
IPC分类号： G06F9/44 , G06F11/34 , G09B7/02 , H04N5/76
CPC分类号： G09B7/02 , G06F9/451 , G06F11/3419 , G06F11/3438 , G06F11/3466 , G06F11/3476 , G06F2201/86
摘要： An automated system and method for conducting a usability test. The system conducts the usability test and records events that occur on the computer screen in sync with both the video and audio of the user and creates a complete chronicle of events that occur behind the scenes in the applications and the operating system. The system, depending upon the settings specified in the configuration, also captures other input streams and then saves the complete recording of the usability test, along with all the desired events and captures, in a file format. The system allows a remote viewer to observe, in real time, the recording of the usability test and to set markers at critical moments during the recording which are to be recorded. The system also allows the manager or administrator to configure the preferences, import and analyze the usability test and recording files, and prepare presentation videos of the usability test based upon the analyzed criteria.
摘要翻译：用于进行可用性测试的自动化系统和方法。系统进行可用性测试并记录计算机屏幕上发生的与用户的视频和音频同步的事件，并创建在应用程序和操作系统中的幕后事件的完整纪事。根据配置中指定的设置，系统还会捕获其他输入流，然后以文件格式保存可用性测试的完整记录以及所有所需的事件和捕获。该系统允许远程观察者实时观察可用性测试的记录，并在录制期间的关键时刻设置标记。该系统还允许管理员或管理员配置首选项，导入和分析可用性测试和记录文件，并根据分析的标准准备可用性测试的演示视频。

9. 外观设计

USD925804S1 Modular illumination unit 有权
公开(公告)号：USD925804S1
公开(公告)日：2021-07-20
申请号：US29684396
申请日：2019-03-20
申请人： William Hamilton
设计人： William Hamilton

10. 外观设计

USD897160S1 Cooler plug 有权
公开(公告)号：USD897160S1
公开(公告)日：2020-09-29
申请号：US29684068
申请日：2019-03-18
申请人： William Hamilton
设计人： William Hamilton
摘要： FIG. 1 is a top, front, left side perspective view of a cooler plug showing my new design.
FIG. 2 is a bottom, rear, right side perspective view thereof; and,
FIG. 3 is a top perspective view thereof.

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