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1. 发明申请

US20080097276A1 IMPLANTABLE CEREBRAL SPINAL FLUID DRAINAGE SYSTEM 有权
标题翻译：可植入的脊椎脊髓液排泄系统
公开(公告)号：US20080097276A1
公开(公告)日：2008-04-24
申请号：US11736887
申请日：2007-04-18
申请人： William Bertrand , Derek Harper , Lori Cone Speckman , Andrew Kiehl , Ron Scheer
发明人： William Bertrand , Derek Harper , Lori Cone Speckman , Andrew Kiehl , Ron Scheer
IPC分类号： A61M5/00
CPC分类号： A61M27/006 , A61M1/0031 , A61M2202/0464 , A61M2205/3515 , A61M2205/3523 , A61M2205/52 , A61M2230/04 , A61M2230/08 , A61M2230/62 , A61M2230/63
摘要： Drainage system including a ventricular catheter, a drainage catheter, and a positive displacement pump that can function to actively drain CSF from the ventricles of the brain of a patient. Methods of using a drainage system in accordance with the invention are also disclosed, as well as kits.
摘要翻译：排水系统包括心室导管，排液导管和积极排泄泵，其可用于从患者脑部积极排出脑脊液。还公开了使用根据本发明的排水系统的方法以及试剂盒。

2. 发明授权

US09393136B2 Variable zone high metal to vessel ratio stent and method 有权
标题翻译：可变区高金属与血管比支架及方法
公开(公告)号：US09393136B2
公开(公告)日：2016-07-19
申请号：US13430907
申请日：2012-03-27
申请人： Keith Perkins , Samuel Robaina , Jeffery Argentine , Walter Bruszewski , Andrew Kiehl
发明人： Keith Perkins , Samuel Robaina , Jeffery Argentine , Walter Bruszewski , Andrew Kiehl
IPC分类号： A61F2/06 , A61F2/04 , A61F2/915 , A61F2/07 , A61F2/90 , A61F2/91 , A61F2/848
CPC分类号： A61F2/915 , A61F2/07 , A61F2/90 , A61F2/91 , A61F2002/061 , A61F2002/065 , A61F2002/8486 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2230/0013 , A61F2250/0018 , A61F2250/0029
摘要： A variable zone high metal to vessel ratio stent includes a proximal high metal to vessel ratio zone, a central low metal to vessel ratio zone, and a distal high metal to vessel ratio zone. The proximal high metal to vessel ratio zone is deployed with fixation and sealing to healthy tissue of a main vessel superior to branch vessels and an aneurysm. The central low metal to vessel ratio zone is deployed directly on ostai of the branch vessels. However, as the central low metal to vessel ratio zone is highly permeable, blood flows from the main vessel through the central low metal to vessel ratio zone and into branch vessels.
摘要翻译：可变区高金属与血管比例支架包括近端高金属与血管比例区域，中心低金属与血管比例区域和远端高金属与血管比例区域。近端高金属与血管比例区域以固定和密封方式部署在主血管的优于分支血管和动脉瘤的健康组织上。中心的低金属与血管比例区域直接部署在分支血管的Ostai上。然而，由于中心的低金属与血管比例区域是高度可渗透的，血液从主血管通过中心的低金属到血管比例区域流入分支血管。

3. 发明授权

US09005270B2 High metal to vessel ratio stent and method 有权
标题翻译：高金属与血管比支架和方法
公开(公告)号：US09005270B2
公开(公告)日：2015-04-14
申请号：US13430942
申请日：2012-03-27
申请人： Keith Perkins , Samuel Robaina , Jeffery Argentine , Walter Bruszewski , Andrew Kiehl
发明人： Keith Perkins , Samuel Robaina , Jeffery Argentine , Walter Bruszewski , Andrew Kiehl
IPC分类号： A61F2/82 , A61F2/915
CPC分类号： A61F2/915 , A61F2002/91525
摘要： A method includes covering ostai of branch vessels emanating from a main vessel and an aneurysm with a high metal to vessel ratio stent. A metal to vessel ratio of the high metal to vessel ratio stent is sufficiently high to encourage tissue ingrowth around the high metal to vessel ratio stent yet is sufficiently low to ensure perfusion of the branch vessels through the high metal to vessel ratio stent. The ingrowth of tissue provides secure fixation and sealing of the high metal to vessel ratio stent to the main vessel and remodels and essentially eliminates the aneurysm. Further, as the entire high metal to vessel ratio stent is permeably, the high metal to vessel ratio stent is deployed without having to rotationally position the high metal to vessel ratio stent.
摘要翻译：一种方法包括覆盖从主血管发出的分支血管和具有高金属与血管比例支架的动脉瘤。高金属与血管比支架的金属与血管比例足够高以促使组织向内生长高金属与血管比例支架，但足够低以确保分支血管通过高金属与血管比例的支架灌注。组织的向内生长提供了高金属与血管比例支架到主血管的牢固固定和密封，并且改造并且基本上消除了动脉瘤。此外，随着整个高金属与血管比例的支架是可渗透的，高金属与血管比例的支架被展开，而不必旋转地定位高金属与血管比例的支架。

4. 发明申请

US20130261728A1 HIGH METAL TO VESSEL RATIO STENT AND METHOD 有权
标题翻译：高金属到船舶比例的方法和方法
公开(公告)号：US20130261728A1
公开(公告)日：2013-10-03
申请号：US13430942
申请日：2012-03-27
申请人： Keith PERKINS , Samuel Robaina , Jeffery Argentine , Walter Bruszewski , Andrew Kiehl
发明人： Keith PERKINS , Samuel Robaina , Jeffery Argentine , Walter Bruszewski , Andrew Kiehl
IPC分类号： A61F2/84 , A61F2/82
CPC分类号： A61F2/915 , A61F2002/91525
摘要： A method includes covering ostai of branch vessels emanating from a main vessel and an aneurysm with a high metal to vessel ratio stent. A metal to vessel ratio of the high metal to vessel ratio stent is sufficiently high to encourage tissue ingrowth around the high metal to vessel ratio stent yet is sufficiently low to ensure perfusion of the branch vessels through the high metal to vessel ratio stent. The ingrowth of tissue provides secure fixation and sealing of the high metal to vessel ratio stent to the main vessel and remodels and essentially eliminates the aneurysm. Further, as the entire high metal to vessel ratio stent is permeably, the high metal to vessel ratio stent is deployed without having to rotationally position the high metal to vessel ratio stent.
摘要翻译：一种方法包括覆盖从主血管发出的分支血管和具有高金属与血管比例支架的动脉瘤。高金属与血管比支架的金属与血管比例足够高以促使组织向内生长高金属与血管比例支架，但足够低以确保分支血管通过高金属与血管比例的支架灌注。组织的向内生长提供了高金属与血管比例支架到主血管的牢固固定和密封，并且改造并且基本上消除了动脉瘤。此外，随着整个高金属与血管比例的支架是可渗透的，高金属与血管比例的支架被展开，而不必旋转地定位高金属与血管比例的支架。

5. 发明申请

US20130261732A1 INTEGRATED MESH HIGH METAL TO VESSEL RATIO STENT AND METHOD 有权
标题翻译：一体化高金属到船舶比例的方法和方法
公开(公告)号：US20130261732A1
公开(公告)日：2013-10-03
申请号：US13431732
申请日：2012-03-27
申请人： Kieth Perkins , Samuel Robaina , Jeffery Argentine , Walter Bruszewski , Andrew Kiehl
发明人： Kieth Perkins , Samuel Robaina , Jeffery Argentine , Walter Bruszewski , Andrew Kiehl
IPC分类号： A61F2/82 , C23F1/02 , B23K26/00
CPC分类号： A61F2/07 , A61F2/915 , A61F2002/061 , A61F2240/001
摘要： A method includes covering ostai of branch vessels emanating from a main vessel and an aneurysm with an integrated mesh high metal to vessel ratio stent. The integrated mesh high metal to vessel ratio stent includes serpentine rings integrated with an integrated mesh having holes formed therein. A metal to vessel ratio of the integrated mesh high metal to vessel ratio stent is sufficiently high to encourage tissue ingrowth around the integrated mesh high metal to vessel ratio stent yet is sufficiently low to ensure perfusion of the branch vessels through the integrated mesh high metal to vessel ratio stent.
摘要翻译：一种方法包括覆盖从主血管发出的分支血管和具有整合的网状高金属比血管支架的动脉瘤。集成网格高金属与容器比例支架包括与其中形成有孔的整体网格集成的蛇形环。一体化网状高金属与血管比例支架的金属与血管比例足够高，以促进组合网格高金属与血管比支架之间的组织向内生长，但足够低以确保分支血管通过整体网格高金属的灌注至血管比例支架。

6. 发明授权

US08911490B2 Integrated mesh high metal to vessel ratio stent and method 有权
标题翻译：综合网格高金属与血管比支架及方法
公开(公告)号：US08911490B2
公开(公告)日：2014-12-16
申请号：US13431732
申请日：2012-03-27
申请人： Keith Perkins , Samuel Robaina , Jeffery Argentine , Walter Bruszewski , Andrew Kiehl
发明人： Keith Perkins , Samuel Robaina , Jeffery Argentine , Walter Bruszewski , Andrew Kiehl
IPC分类号： A61F2/82
CPC分类号： A61F2/07 , A61F2/915 , A61F2002/061 , A61F2240/001
摘要： A method includes covering ostai of branch vessels emanating from a main vessel and an aneurysm with an integrated mesh high metal to vessel ratio stent. The integrated mesh high metal to vessel ratio stent includes serpentine rings integrated with an integrated mesh having holes formed therein. A metal to vessel ratio of the integrated mesh high metal to vessel ratio stent is sufficiently high to encourage tissue ingrowth around the integrated mesh high metal to vessel ratio stent yet is sufficiently low to ensure perfusion of the branch vessels through the integrated mesh high metal to vessel ratio stent.
摘要翻译：一种方法包括覆盖从主血管发出的分支血管和具有整合的网状高金属比血管支架的动脉瘤。集成网格高金属与容器比例支架包括与其中形成有孔的整体网格集成的蛇形环。一体化网状高金属与血管比例支架的金属与血管比例足够高，以促进组合网格高金属与血管比支架之间的组织向内生长，但足够低以确保分支血管通过整体网格高金属的灌注至血管比例支架。

7. 发明申请

US20130261727A1 VARIABLE ZONE HIGH METAL TO VESSEL RATIO STENT AND METHOD 有权
标题翻译：可变区高金属到船舶比例的方法和方法
公开(公告)号：US20130261727A1
公开(公告)日：2013-10-03
申请号：US13430907
申请日：2012-03-27
申请人： Keith PERKINS , Samuel Robaina , Jeffery Argentine , Walter Bruszewski , Andrew Kiehl
发明人： Keith PERKINS , Samuel Robaina , Jeffery Argentine , Walter Bruszewski , Andrew Kiehl
IPC分类号： A61F2/06 , A61F2/84
CPC分类号： A61F2/915 , A61F2/07 , A61F2/90 , A61F2/91 , A61F2002/061 , A61F2002/065 , A61F2002/8486 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2230/0013 , A61F2250/0018 , A61F2250/0029
摘要： A variable zone high metal to vessel ratio stent includes a proximal high metal to vessel ratio zone, a central low metal to vessel ratio zone, and a distal high metal to vessel ratio zone. The proximal high metal to vessel ratio zone is deployed with fixation and sealing to healthy tissue of a main vessel superior to branch vessels and an aneurysm. The central low metal to vessel ratio zone is deployed directly on ostai of the branch vessels. However, as the central low metal to vessel ratio zone is highly permeable, blood flows from the main vessel through the central low metal to vessel ratio zone and into branch vessels.
摘要翻译：可变区高金属与血管比例支架包括近端高金属与血管比例区域，中心低金属与血管比例区域和远端高金属与血管比例区域。近端高金属与血管比例区域部署有固定和密封到主血管的健康组织，优于分支血管和动脉瘤。中心的低金属与血管比例区域直接部署在分支血管的Ostai上。然而，由于中心的低金属与血管比例区域是高度可渗透的，血液从主血管通过中心的低金属到血管比例区域流入分支血管。

8. 发明申请

US20120271399A1 High Metal to Vessel Ratio Landing Zone Stent-Graft and Method 审中-公开
标题翻译：高金属到船舶比登陆区支架移植和方法
公开(公告)号：US20120271399A1
公开(公告)日：2012-10-25
申请号：US13089803
申请日：2011-04-19
申请人： Keith Perkins , Samuel Robaina , Jeffery Argentine , Walter Bruszewski , Andrew Kiehl
发明人： Keith Perkins , Samuel Robaina , Jeffery Argentine , Walter Bruszewski , Andrew Kiehl
IPC分类号： A61F2/84 , A61F2/82
CPC分类号： A61F2/07 , A61F2/89 , A61F2/962 , A61F2002/061 , A61F2002/075 , A61F2230/0067
摘要： A method includes covering an ostium of a branch vessel emanating from a main vessel with a proximal landing zone of a high metal to vessel ratio landing zone stent-graft, wherein a metal to vessel ratio of the proximal landing zone when deployed is sufficiently high to encourage tissue ingrowth around the proximal landing zone yet is sufficiently low to ensure perfusion of the branch vessel through the proximal landing zone. The method further includes covering an aneurysm of the main vessel with an exclusion zone of the high metal to vessel ratio landing zone stent-graft, the exclusion zone being formed of graft material. By forming the exclusion zone of graft material, excellent exclusion of the aneurysm is achieved.
摘要翻译：一种方法包括覆盖从主血管发出的分支血管的口，其具有高金属与血管比例着陆区支架移植物的近端着陆区，其中近端着陆区的部署时的金属与血管比例足够高以至鼓励组织沿近端着陆区向内生长但足够低以确保分支血管通过近端着陆区的灌注。该方法还包括用高金属与血管比例着陆区域支架移植物的排除区覆盖主血管的动脉瘤，所述排除区由移植材料形成。通过形成移植材料的排除区，实现了动脉瘤的优异排除。

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