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1. 发明授权

US5742972A Toothbrush 失效
公开(公告)号：US5742972A
公开(公告)日：1998-04-28
申请号：US803704
申请日：1997-02-21
申请人： William A. Bredall , Miklos M. Breuer , Ximena A. Gavino , Christopher Loew , Jeffrey Scott Meessmann , Douglas J. McDowell , Alberto B. Sabato , Jean L. Spencer , James D. Vidra , Stanley Wreford
发明人： William A. Bredall , Miklos M. Breuer , Ximena A. Gavino , Christopher Loew , Jeffrey Scott Meessmann , Douglas J. McDowell , Alberto B. Sabato , Jean L. Spencer , James D. Vidra , Stanley Wreford
IPC分类号： A46B9/04
CPC分类号： A46B9/026 , Y10S15/05
摘要： The present invention relates to a toothbrush which exhibits superior interproximal and gingival margin cleaning. The toothbrush includes an elongated handle member connected to a toothbrush head member. The head is divided into two regions. A "toe" region is defined as the part of the head which is furthest from the handle and a "heel" region is the portion of the head which is closest to the handle. A multiplicity of bristles extend from the heel region of the head; the distal ends of these bristles form a longitudinally aligned concave shape when viewed on end. Likewise, a multiplicity of bristles extend from the toe region of the head, wherein said bristles extending from the toe portion of the head are at least as tall as the general height of said bristles extending from the heel portion when viewed from the side and wherein the side profile view of the distal ends of the bristles extending from the toe portion form a generally linear surface which forms an angle relative to the general plane of the bristles extending from the heel portion of from 0.degree. to about 45.degree. declining from the edge of the toe portion distal to the heel portion to the edge of the toe portion which is proximal to the heel portion.

2. 发明授权

US06108851A Toothbrush 有权
标题翻译：牙刷
公开(公告)号：US06108851A
公开(公告)日：2000-08-29
申请号：US410703
申请日：1999-10-01
申请人： William A. Bredall , Miklos M. Breuer , Ximena A. Gavino , Christopher Loew , Jeffrey Scott Meessmann , Douglas J. McDowell , Alberto B. Sabato , Jean L. Spencer , James D. Vidra , Stanley Wreford
发明人： William A. Bredall , Miklos M. Breuer , Ximena A. Gavino , Christopher Loew , Jeffrey Scott Meessmann , Douglas J. McDowell , Alberto B. Sabato , Jean L. Spencer , James D. Vidra , Stanley Wreford
IPC分类号： A46B9/04
CPC分类号： A46B9/026 , A46B9/045 , Y10S15/05
摘要： The present invention relates to a toothbrush which exhibits superior interproximal and gingival margin cleaning. The toothbrush includes an elongated handle member connected to a toothbrush head member. The head is divided into two regions. A "toe" region is defined as the part of the head which is furthest from the handle and a "heel" region is the portion of the head which is closest to the handle. A multiplicity of bristles extend from the heel region of the head; the distal ends of these bristles form a longitudinally aligned concave shape when viewed on end. Likewise, a multiplicity of bristles extend from the toe region of the head, wherein said bristles extending from the toe portion of the head are at least as tall as the general height of said bristles extending from the heel portion when viewed from the side and wherein the side profile view of the distal ends of the bristles extending from the toe portion form a generally linear surface which forms an angle relative to the general plane of the bristles extending from the heel portion of from 0.degree. to about 45.degree. declining from the edge of the toe portion distal to the heel portion to the edge of the toe portion which is proximal to the heel portion.
摘要翻译：本发明涉及牙刷，其显示出优异的邻间和牙龈边缘清洁。牙刷包括连接到牙刷头部件的细长手柄部件。头部分为两个区域。 “脚趾”区域被定义为距手柄最远的头部的一部分，并且“跟部”区域是头部最接近手柄的部分。多个刷毛从头部的跟部区域延伸; 当从末端看时，这些刷毛的远端形成纵向对准的凹形。类似地，多个刷毛从头部的趾部区域延伸，其中从头部的趾部延伸的所述刷毛至少与从侧面观察时从后跟部分延伸的所述刷毛的总高度一样高，并且其中从趾部延伸的刷毛的远端的侧剖视图形成大致线性的表面，其相对于从0°至约45°的跟部延伸的刷毛的总平面形成一角度，从0°至约45°的边缘的脚趾部分远离脚跟部分到脚趾部分的靠近跟部部分的边缘。

3. 发明授权

US6006394A Toothbrush 失效
公开(公告)号：US6006394A
公开(公告)日：1999-12-28
申请号：US879228
申请日：1997-06-19
申请人： William A. Bredall , Miklos M. Breuer , Ximena A. Gavino , Christopher Loew , Jeffrey Scott Meessmann , Douglas J. McDowell , Alberto B. Sabato , Jean L. Spencer , James D. Vidra , Stanley Wreford
发明人： William A. Bredall , Miklos M. Breuer , Ximena A. Gavino , Christopher Loew , Jeffrey Scott Meessmann , Douglas J. McDowell , Alberto B. Sabato , Jean L. Spencer , James D. Vidra , Stanley Wreford
IPC分类号： A46B9/04
CPC分类号： A46B9/026 , A46B9/045 , Y10S15/05
摘要： The present invention relates to a toothbrush which exhibits superior interproximal and gingival margin cleaning. The toothbrush includes an elongated handle member connected to a toothbrush head member. The head is divided into two regions. A "toe" region is defined as the part of the head which is furthest from the handle and a "heel" region is the portion of the head which is closest to the handle. A multiplicity of bristles extend from the heel region of the head; the distal ends of these bristles form a longitudinally aligned concave shape when viewed on end. Likewise, a multiplicity of bristles extend from the toe region of the head, wherein said bristles extending from the toe portion of the head are at least as tall as the general height of said bristles extending from the heel portion when viewed from the side and wherein the side profile view of the distal ends of the bristles extending from the toe portion form a generally linear surface which forms an angle relative to the general plane of the bristles extending from the heel portion of from 0.degree. to about 45.degree. declining from the edge of the toe portion distal to the heel portion to the edge of the toe portion which is proximal to the heel portion.

4. 发明授权

US5396678A Toothbrush with rectangular bristles 失效
标题翻译：具有矩形刷毛的牙刷
公开(公告)号：US5396678A
公开(公告)日：1995-03-14
申请号：US970331
申请日：1992-11-02
申请人： William A. Bredall , Miklos M. Breuer , Ximena A. Gavino , Christopher Loew , Jeffrey S. Meessmann , Douglas J. McDowell , Alberto B. Sabato , Jean L. Spencer , James D. Vidra , Stanley Wreford
发明人： William A. Bredall , Miklos M. Breuer , Ximena A. Gavino , Christopher Loew , Jeffrey S. Meessmann , Douglas J. McDowell , Alberto B. Sabato , Jean L. Spencer , James D. Vidra , Stanley Wreford
IPC分类号： A46B3/22 , A46B5/00 , A46B9/04 , A46D1/00
CPC分类号： A46D1/0238 , A46B9/04 , A46D1/00 , A46B2200/1066
摘要： The present invention relates to a toothbrush which exhibits improved tooth and gum cleaning. The toothbrush includes an elongated handle member connected to a toothbrush head member. A multiplicity of bristles extend from the head member; these bristles being comprised of at least two general directional orientations of bristles having a generally rectangular cross-section.
摘要翻译：本发明涉及一种牙刷，其具有改进的牙齿和牙龈清洁。牙刷包括连接到牙刷头部件的细长手柄部件。多个刷毛从头部构件延伸; 这些刷毛由具有大致矩形横截面的刷毛的至少两个总方向取向组成。

5. 发明授权

US4140758A Oral compositions containing dextranase 失效
公开(公告)号：US4140758A
公开(公告)日：1979-02-20
申请号：US714555
申请日：1976-08-16
申请人： James D. Vidra , Julius H. Nachtigal
发明人： James D. Vidra , Julius H. Nachtigal
IPC分类号： A61K8/19 , A61K8/66 , A61Q11/00 , A61K7/28 , A61K37/48 , A61K37/54
CPC分类号： A61Q11/00 , A61K8/19 , A61K8/66 , A61K2800/52
摘要： Oral compositions containing dextranase and a stabilizer/activator selected from the group consisting of manganeous ions, calcium ions, magnesium ions, and mixtures thereof.

6. 发明授权

US4360512A Nonabrasive gel formulations of sulfonated poly(arylene ether sulfone) polymer dental plaque barriers 失效
标题翻译：磺化聚（亚芳基醚砜）聚合物牙菌斑的非磨损凝胶制剂
公开(公告)号：US4360512A
公开(公告)日：1982-11-23
申请号：US172350
申请日：1980-07-25
申请人： James D. Vidra
发明人： James D. Vidra
IPC分类号： A61K8/86 , A61Q11/00 , C08G65/48 , C08G75/23 , C08L71/00 , C08L81/06 , A61K7/16 , A61K7/22 , A61K31/185 , A61K31/315
CPC分类号： A61K8/90 , A61K8/042 , A61K8/86 , A61Q11/00 , C08G65/48 , C08G75/23 , C08L71/00 , C08L81/06
摘要： Compositions for preventing the attachment of dental plaque to the surfaces of the teeth comprise certain sulfonated poly(arylene ether sulfone) polymers and the pharmaceutically acceptable salts thereof in a pharmaceutically acceptable nonabrasive gel vehicle comprising a selected polyoxypropylene/polyoxyethylene block copolymer as the principal gelling agent.
摘要翻译：用于防止牙斑附着到牙齿表面的组合物包含某些磺化聚（亚芳基醚砜）聚合物及其药学上可接受的盐在药学上可接受的非磨蚀性凝胶载体中，其包含选择的聚氧丙烯/聚氧乙烯嵌段共聚物作为主要胶凝剂。

7. 发明授权

US4601899A Hydrous toothpaste containing TiF.sub.4 and chelating agent 失效
标题翻译：含有TiF4和螯合剂的含水牙膏
公开(公告)号：US4601899A
公开(公告)日：1986-07-22
申请号：US716552
申请日：1985-03-27
申请人： Roger E. Stier , William H. Dunn , James D. Vidra
发明人： Roger E. Stier , William H. Dunn , James D. Vidra
IPC分类号： A61K8/21 , A61K8/365 , A61Q11/00 , A61K7/18 , A61K33/16
CPC分类号： A61Q11/00 , A61K8/21 , A61K8/365 , A61K2800/51
摘要： An extrudable, shape-retaining aqueous toothpaste which comprises an anti-caries effective amount of TiF.sub.4, a dental polishing or abrasive agent, a chelating agent in an amount effective to stabilize the TiF.sub.4, and an aqueous dental vehicle, said aqueous toothpaste having a pH of at least about 3.5.
摘要翻译：一种可挤出形状保持水性牙膏，其包含抗龋齿有效量的TiF4，牙科研磨剂或研磨剂，有效稳定TiF4的螯合剂和水性牙科载体，所述水性牙膏具有pH 至少约3.5。

8. 发明授权

US4205061A Oral antimicrobial compositions 失效
标题翻译：口服抗微生物组合物
公开(公告)号：US4205061A
公开(公告)日：1980-05-27
申请号：US924764
申请日：1978-07-14
申请人： James D. Vidra
发明人： James D. Vidra
IPC分类号： C07D213/20 , A61K8/42 , A61K8/49 , A61K31/44 , A61K31/4425 , A61K31/60 , A61K31/625 , A61P1/02 , A61Q11/00 , A61K7/24
CPC分类号： A61K8/4926 , A61K8/42 , A61Q11/00 , A61K2800/59
摘要： Novel oral antimicrobial compositions comprising a synergistic combination of a specific halogenated salicylanilide and a specific quaternary ammonium compound are disclosed.
摘要翻译：公开了包含特定卤化水杨酰苯胺和特定季铵化合物的协同组合的新型口服抗微生物组合物。

9. 发明授权

US4601898A Aqueous solution containing TiF.sub.4 and chelating agent 失效
标题翻译：含有TiF4和螯合剂的水溶液
公开(公告)号：US4601898A
公开(公告)日：1986-07-22
申请号：US716491
申请日：1985-03-27
申请人： Roger E. Stier , William H. Dunn , James D. Vidra
发明人： Roger E. Stier , William H. Dunn , James D. Vidra
IPC分类号： A61K8/21 , A61K8/365 , A61Q11/00 , A61K7/18 , A61K33/16
CPC分类号： A61Q11/00 , A61K8/21 , A61K8/365 , A61K2800/51
摘要： An anti-caries aqueous solution, which comprises an aqueous solution containing an anti-caries effective amount of TiF.sub.4 and a chelating agent in an amount effective to stablilize the TiF.sub.4, said solution having a pH of at least about 3.5.
摘要翻译：一种抗龋水溶液，其包含含有抗龋齿有效量的TiF 4的水溶液和有效稳定TiF 4的量的螯合剂，所述溶液具有至少约3.5的pH。

10. 发明授权

US4568534A Dentifrices 失效
标题翻译：牙粉
公开(公告)号：US4568534A
公开(公告)日：1986-02-04
申请号：US699168
申请日：1985-02-07
申请人： Roger E. Stier , James D. Vidra , Bernard Misek
发明人： Roger E. Stier , James D. Vidra , Bernard Misek
IPC分类号： A61K8/49 , A61Q11/00 , A61K7/16 , A61K7/18
CPC分类号： A61K8/4973 , A61K8/4926 , A61Q11/00 , A61K2800/45
摘要： A dentifrice containing an anticaries agent and an abrasive is produced to which has been added at least one color indicator which, when the user brushes his or her teeth with the dentifrice, results in a color change in the dentifrice within the user's mouth after a predetermined period of brushing time has elapsed for the purpose of indicating to the user that he or she has brushed his or her teeth a sufficient length of time.
摘要翻译：产生含有防龋剂和研磨剂的洁齿剂，至少添加了一种颜色指示剂，当使用者用洁齿剂刷牙时，会导致使用者口腔内洁牙剂的颜色变化，刷牙时间已经过去了，目的是向用户指示他或她已经刷牙了足够长的时间。

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