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1. 发明授权

US4003997A Heart glycosides and process for preparing them 失效
标题翻译：心脏糖苷及其制备方法
公开(公告)号：US4003997A
公开(公告)日：1977-01-18
申请号：US496892
申请日：1974-08-12
申请人： Ulrich Stache , Kurt Radscheit , Werner Fritsch , Werner Haede , Ernst Lindner
发明人： Ulrich Stache , Kurt Radscheit , Werner Fritsch , Werner Haede , Ernst Lindner
IPC分类号： C07J71/00 , C07J19/00 , A61K31/70
CPC分类号： C07J19/00
摘要： Cyclic 2',3'-ethers of 3-hydroxy-14,15.beta.-oxido-14.beta.-bufa-4,20,22-trienolide, 3.beta.-(.alpha.-L-rhamnopyranoside) and process for preparing them. The compounds have a strongly positive inotropic activity and may be used in the therapy of cardiac insufficiency.
摘要翻译： 3-羟基-14,15β-氧代-14β-bufa-4,20,22-三烯内酯，3β-（α-L-鼠李糖吡喃糖苷）的环状2'，3'-醚及其制备方法。该化合物具有强烈的正性肌力活性，可用于治疗心功能不全。

2. 发明授权

US4191765A 1-Aryloxy-2-hydroxy-3-aminopropanes 失效
标题翻译： 1-芳氧基-2-羟基-3-氨基丙烷
公开(公告)号：US4191765A
公开(公告)日：1980-03-04
申请号：US932504
申请日：1978-08-10
申请人： Werner Fritsch , Ulrich Stache , Ernst Lindner
发明人： Werner Fritsch , Ulrich Stache , Ernst Lindner
IPC分类号： C07D211/14 , C07D295/092 , C07D295/112 , A61K31/215 , A61K31/275 , C07C69/76 , C07C121/80
CPC分类号： C07D295/088 , C07D211/14 , C07D295/112
摘要： Compounds of formula I ##STR1## wherein R.sup.1 and R.sup.1' are identical or different and represent hydrogen, an alkyl radical or alkoxy radical having 1-4 carbon atoms, the allyl group, a halogen atom or the nitro group, R.sup.2 represents an acrylic acid radical or an acrylic acid nitrile radical of the formulae ##STR2## wherein R.sup.5 represents hydrogen, an alkyl radical having 1-5 carbon atoms, an aryl radical or aryl-lower alkyl radical either unsubstituted or substituted by lower alkyl or alkoxy, R.sup.6 represents hydrogen or an alkyl radical having 1-8 carbon atoms, R.sup.7 represents hydrogen, a lower alkyl radical or an aryl-lower alkyl radical, R.sup.3 and R.sup.4 represent together with the nitrogen atom a heterocyclic ring with 5-7 members being optionally substituted by C.sub.1 -C.sub.4 alkyl, in which ring one carbon atom may be replaced by one oxygen atom, sulfur atom or one further nitrogen atom, the latter may be substituted, or wherein R.sup.3 represents hydrogen and R.sup.4 represents a phenyl-alkylene or phenyl-alkylidene radical of the formula ##STR3## in which Alk is alkyl having 1 to 3 carbon atoms, and n is a figure from 1-3, and R.sup.8 and R.sup.9 are identical or different and represent hydrogen, an alkoxy radical having 1-3 carbon atoms or the benzoyl radical or R.sup.8 and R.sup.9 represent together the bismethylene dioxy radical, as well as the physiologically compatible acid addition salts and a process for preparing these compounds.
摘要翻译：式I的化合物其中R 1和R 1'相同或不同并且表示氢，具有1-4个碳原子的烷基或烷氧基，烯丙基，卤原子或硝基，R 2表示丙烯酸酸基或丙烯酸腈基，其中R 5表示氢，具有1-5个碳原子的烷基，未取代或被低级烷基或烷氧基取代的芳基或芳基 - 低级烷基，R 6表示氢或具有1-8个碳原子的烷基，R7表示氢，低级烷基或芳基 - 低级烷基，R3和R4与氮原子一起表示与5-7个成员任选被C1取代的杂环 -C 1-4烷基，其中一个碳原子可以被一个氧原子，硫原子或一个另外的氮原子代替，后者可以被取代，或其中R3代表氢，R4代表苯基亚烷基或苯基亚烷基其中Alk是具有1至3个碳原子的烷基，n是1-3的数字，R8和R9相同或不同并表示氢，具有1-3个碳原子的烷氧基的式“IMAGE”的基团原子或苯甲酰基或R8和R9一起表示双亚乙基二氧自由基，以及生理上相容的酸加成盐和制备这些化合物的方法。

3. 发明授权

US3950323A Digoxigenine-3-[2',3'-didesoxy-glycosides] and a process for their manufacture 失效
标题翻译： DIGOXIGENINE-3-（2'，3'-DIDESOXY-GLYCOSIDES）+0及其制造方法
公开(公告)号：US3950323A
公开(公告)日：1976-04-13
申请号：US416656
申请日：1973-11-16
申请人： Ulrich Stache , Werner Fritsch , Werner Haede , Ernst Lindner
发明人： Ulrich Stache , Werner Fritsch , Werner Haede , Ernst Lindner
IPC分类号： C07J19/00 , A61K31/585
CPC分类号： C07J19/00 , Y10S514/869
摘要： Digoxigenine-3-[2', 3'-didesoxy-glycosides] of the formula ##SPC1##In which R.sup.1 is the digoxigenine radical and R.sup.2 is hydrogen, methyl or --CH.sub.2 OH, which are prepared by a reaction of a digoxigenine-12-monoacylate with an acylated 1,2-glycal, a catalytic hydrogenation of the 12-acylates obtained and a subsequent hydrolysis. The products have a cardiotonic, diuretic and especially venotonic activity.

4. 发明授权

US5568724A Turbofan engine with means to smooth intake air 失效
标题翻译： Turbofan发动机有平滑进气的手段
公开(公告)号：US5568724A
公开(公告)日：1996-10-29
申请号：US211798
申请日：1994-06-27
申请人： Ernst Lindner , Guido W. Trittler , Klaus Britz
发明人： Ernst Lindner , Guido W. Trittler , Klaus Britz
IPC分类号： F02C7/04 , F02K1/28 , F02K1/66 , F02K7/10 , F02K1/64
CPC分类号： F02K1/66 , F02K1/28 , Y10S415/914
摘要： A turbojet fan engine is disclosed having a fan or prop fan which blows air into a secondary channel and an external shroud for the turbine and the secondary channel, in which the front end of the shroud is formed with an inlet lip and the rear end of the shroud is formed in a nozzle-like, pointed manner and at least one end of the shroud is changed, with respect to its effective profile geometry, by means of air under pressure which is taken from the engine and blown out at the appropriate end of the shroud.
摘要翻译： PCT No.PCT / EP92 / 02274 371日期1994年6月27日第 102（e）日期1994年6月27日PCT提交1992年10月1日PCT公布。出版物WO93 / 08397 日期：1993年04月29日公开了一种涡轮喷气发动机发动机，其具有将空气吹入第二通道的风扇或风扇风扇，以及用于涡轮和第二通道的外部罩，其中，护罩的前端形成有入口唇并且护罩的后端形成为喷嘴状的尖锐方式，并且护罩的至少一端相对于其有效的轮廓几何形状通过在发动机中被吹取的压力下的空气而被改变在护罩的适当端部出来。

5. 发明授权

US5464325A Turbo-compressor impeller for coolant 失效
标题翻译：用于冷却液的涡轮压缩机叶轮
公开(公告)号：US5464325A
公开(公告)日：1995-11-07
申请号：US266940
申请日：1994-06-27
申请人： Peter Albring , Rainer Apley , Klaus Doge , Gunter Heinrich , Ernst Lindner , Norbert Muller , Reinhard Pauer , Eberhard Pilling , Rainer Rudischer
发明人： Peter Albring , Rainer Apley , Klaus Doge , Gunter Heinrich , Ernst Lindner , Norbert Muller , Reinhard Pauer , Eberhard Pilling , Rainer Rudischer
IPC分类号： F04D29/02 , F04D29/28 , F01D5/32
CPC分类号： F04D29/284 , F04D29/023 , F05D2300/43 , F05D2300/603
摘要： A refrigerant or coolant compressor of the radial type with an impeller hng a plurality of vane elements can be used for compressing water vapor as a refrigerant or coolant under vacuum conditions. The impeller of the compressor is constructed to produce a high volume flow rate at the required compression ratio, in view of the low density of water vapor as the preferred flow medium. The impeller has sufficient strength to operate at the required high circumferential velocities. The impeller includes vane elements, disk elements, vane support elements and a hub. The vane elements are individually connected to the hub by the support elements. The support elements may be either ring-shaped elements connecting a rear surface of the disk elements to the hub, or may be pin-shaped insert members connecting the root of each vane element to the hub. The components of the impeller are made of a polymer composite material reinforced preferably with carbon fibers.
摘要翻译：具有多个叶片元件的具有叶轮的径向型制冷剂或冷却剂压缩机可用于在真空条件下作为制冷剂或冷却剂压缩水蒸气。鉴于作为优选的流动介质的水蒸气的低密度，压缩机的叶轮被构造成以所需的压缩比产生高体积流量。叶轮具有足够的强度以所需的高周向速度运行。叶轮包括叶片元件，圆盘元件，叶片支撑元件和轮毂。叶片元件通过支撑元件独立地连接到轮毂。支撑元件可以是将盘元件的后表面连接到轮毂的环形元件，或者可以是将每个叶片元件的根部连接到轮毂的销形插入件。叶轮的部件由优选用碳纤维增强的聚合物复合材料制成。

6. 发明授权

US4013791A Peptides having an antihypertensive effect 失效
标题翻译：具有抗真菌作用的肽
公开(公告)号：US4013791A
公开(公告)日：1977-03-22
申请号：US637114
申请日：1975-12-03
申请人： Hans Wissmann , Rolf Geiger , Ernst Lindner , Bernward Scholkens
发明人： Hans Wissmann , Rolf Geiger , Ernst Lindner , Bernward Scholkens
IPC分类号： C07K14/81 , A61K38/00 , C07K1/113 , C07K7/06 , C07K7/14 , A61K37/00 , C07C103/52
CPC分类号： C07K7/14 , A61K38/00 , Y02P20/55 , Y10S530/80
摘要： Novel peptide derivatives and a method of preparing the same are described. These compounds are useful in the diagnosis and treatment of hypertension.

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