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1. 发明授权

US07130375B1 High resolution direct-projection type x-ray microtomography system using synchrotron or laboratory-based x-ray source 有权
标题翻译：使用同步加速器或基于实验室的X射线源的高分辨率直投式X射线显微镜系统
公开(公告)号：US07130375B1
公开(公告)日：2006-10-31
申请号：US11035749
申请日：2005-01-14
申请人： Wenbing Yun , David Dean Scott , David R. Trapp , Frederick William Duewer , Yuxin Wang
发明人： Wenbing Yun , David Dean Scott , David R. Trapp , Frederick William Duewer , Yuxin Wang
IPC分类号： G01N23/20
CPC分类号： G01N23/04 , A61B6/508 , G01N2223/505 , G01N2223/6113
摘要： A projection-based x-ray imaging system combines projection magnification and optical magnification in order to ease constraints on source spot size, while improving imaging system footprint and efficiency. The system enables tomographic imaging of the sample especially in a proximity mode where the same is held in close proximity to the scintillator. In this case, a sample holder is provided that can rotate the sample. Further, a z-axis motion stage is also provided that is used to control distance between the sample and the scintillator.
摘要翻译：基于投影的X射线成像系统结合了投影放大倍数和光学放大倍率，以便减轻源光斑尺寸的限制，同时提高成像系统的覆盖面和效率。该系统使得样品的层析成像特别是在接近模式下，其中相邻的模式保持在闪烁体附近。在这种情况下，提供可以旋转样品的样品架。此外，还提供了用于控制样品和闪烁体之间的距离的z轴运动级。

2. 发明授权

US07400704B1 High resolution direct-projection type x-ray microtomography system using synchrotron or laboratory-based x-ray source 有权
标题翻译：使用同步加速器或基于实验室的X射线源的高分辨率直投式X射线显微镜系统
公开(公告)号：US07400704B1
公开(公告)日：2008-07-15
申请号：US11537806
申请日：2006-10-02
申请人： Wenbing Yun , David Dean Scott , David R. Trapp , Frederick William Duewer , Yuxin Wang
发明人： Wenbing Yun , David Dean Scott , David R. Trapp , Frederick William Duewer , Yuxin Wang
IPC分类号： G01N23/20 , A61B6/08 , H05G1/00
CPC分类号： G01N23/04 , A61B6/508 , G01N2223/505 , G01N2223/6113
摘要： A projection-based x-ray imaging system combines projection magnification and optical magnification in order to ease constraints on source spot size, while improving imaging system footprint and efficiency. The system enables tomographic imaging of the sample especially in a proximity mode where the same is held in close proximity to the scintillator. In this case, a sample holder is provided that can rotate the sample. Further, a z-axis motion stage is also provided that is used to control distance between the sample and the scintillator.
摘要翻译：基于投影的X射线成像系统结合了投影放大倍数和光学放大倍率，以便减轻源光斑尺寸的限制，同时提高成像系统的覆盖面和效率。该系统使得样品的层析成像特别是在接近模式下，其中相邻的模式保持在闪烁体附近。在这种情况下，提供可以旋转样品的样品架。此外，还提供了用于控制样品和闪烁体之间的距离的z轴运动级。

3. 发明授权

US07394890B1 Optimized x-ray energy for high resolution imaging of integrated circuits structures 有权
标题翻译：优化的x射线能量用于集成电路结构的高分辨率成像
公开(公告)号：US07394890B1
公开(公告)日：2008-07-01
申请号：US10983415
申请日：2004-11-08
申请人： Yuxin Wang , Wenbing Yun , Frederick William Duewer
发明人： Yuxin Wang , Wenbing Yun , Frederick William Duewer
IPC分类号： G21K1/06
CPC分类号： G21K7/00 , G21K1/06 , G21K2201/067 , G21K2207/005
摘要： An x-ray imaging system uses particular emission lines that are optimized for imaging specific metallic structures in a semiconductor integrated circuit structures and optimized for the use with specific optical elements and scintillator materials. Such a system is distinguished from currently-existing x-ray imaging systems that primarily use the integral of all emission lines and the broad Bremstralung radiation. The disclosed system provides favorable imaging characteristics such as ability to enhance the contrast of certain materials in a sample, to use different contrast mechanisms in a single imaging system, and to increase the throughput of the system.
摘要翻译： X射线成像系统使用针对半导体集成电路结构中的特定金属结构进行成像而优化的特定发射线，并针对特定的光学元件和闪烁体材料进行优化。这种系统与目前存在的主要使用所有发射线和广泛的布氏体辐射的整体的X射线成像系统不同。所公开的系统提供有利的成像特征，例如增强样品中某些材料的对比度的能力，以在单个成像系统中使用不同的对比度机制，并且增加系统的吞吐量。

4. 发明授权

US07170969B1 X-ray microscope capillary condenser system 有权
标题翻译： X光显微镜毛细管冷凝器系统
公开(公告)号：US07170969B1
公开(公告)日：2007-01-30
申请号：US10704381
申请日：2003-11-07
申请人： Wenbing Yun , Frederick William Duewer , Yuxin Wang
发明人： Wenbing Yun , Frederick William Duewer , Yuxin Wang
IPC分类号： G21K7/00
CPC分类号： G21K7/00 , G21K1/06 , G21K2201/064
摘要： A radiation condenser system for an X-ray microscope allows for the efficient collection and relay of radiation from a source to the sample. It generates a converging hollow cone of radiation that can be used in the imaging of a sample or target using a zone plate lens. This system comprises a capillary tube for receiving and focusing radiation onto a sample. A center stop is provided for blocking radiation being transmitted along an axis of the capillary tube.
摘要翻译：用于X射线显微镜的辐射聚光器系统允许从源到样品的辐射的有效收集和中继。它产生会聚的中空辐射圆锥，可用于使用区域透镜对样品或靶的成像。该系统包括用于接收和聚焦辐射到样品上的毛细管。提供中心止动件用于阻止沿着毛细管的轴传递的辐射。

5. 发明授权

US07297959B2 Lens bonded X-ray scintillator system and manufacturing method therefor 有权
标题翻译：透镜结合X射线闪烁体系及其制造方法
公开(公告)号：US07297959B2
公开(公告)日：2007-11-20
申请号：US11278839
申请日：2006-04-06
申请人： Wenbing Yun , Yuxin Wang , David R. Trapp
发明人： Wenbing Yun , Yuxin Wang , David R. Trapp
IPC分类号： G01T1/20
CPC分类号： G01T1/2002 , G01T1/20
摘要： A scintillated CCD detector system for imaging x rays uses x-rays having a photon energy in the range of 1 to 20 keV. The detector differs from existing systems in that it provides extremely high resolution of better than a micrometer, and high detection quantum efficiency of up to 95%. The design of this detector also allows it to function as an energy filter to remove high-energy x-rays. This detector is useful in a wide range of applications including x-ray imaging, spectroscopy, and diffraction. The scintillator optical system has scintillator material with a lens system for collecting the light that is generated in the scintillator material. A substrate is used for spacing the scintillator material from the lens system.
摘要翻译：用于对x射线进行成像的闪烁CCD检测器系统使用具有在1至20keV范围内的光子能量的X射线。检测器与现有系统不同之处在于它提供比千分尺更高的分辨率，高达95％的高检测量子效率。该检测器的设计也可以用作能量过滤器，以去除高能X射线。该检测器可用于广泛的应用，包括X射线成像，光谱和衍射。闪烁体光学系统具有闪烁体材料，其具有用于收集闪烁体材料中产生的光的透镜系统。衬底用于将闪烁体材料与透镜系统间隔开。

6. 发明授权

US07800072B2 Low pass X-ray scintillator system 有权
标题翻译：低通X射线闪烁体系统
公开(公告)号：US07800072B2
公开(公告)日：2010-09-21
申请号：US11278836
申请日：2006-04-06
申请人： Wenbing Yun , Yuxin Wang , David R. Trapp
发明人： Wenbing Yun , Yuxin Wang , David R. Trapp
IPC分类号： G01T1/20
CPC分类号： G01T1/2002 , G01T1/20
摘要： A scintillated CCD detector system for imaging x rays uses x-rays having a photon energy in the range of 1 to 20 keV. The detector differs from existing systems in that it provides extremely high resolution of better than a micrometer, and high detection quantum efficiency of up to 95%. The design of this detector also allows it to function as an energy filter to remove high-energy x-rays. This detector is useful in a wide range of applications including x-ray imaging, spectroscopy, and diffraction. The scintillator optical system has scintillator material with a lens system for collecting the light that is generated in the scintillator material. A substrate is used for spacing the scintillator material from the lens system.
摘要翻译：用于对X射线成像的闪烁CCD检测器系统使用具有在1至20keV范围内的光子能量的X射线。检测器与现有系统不同之处在于它提供比千分尺更高的分辨率，高达95％的高检测量子效率。该检测器的设计也可以用作能量过滤器，以去除高能X射线。该检测器可用于广泛的应用，包括X射线成像，光谱和衍射。闪烁体光学系统具有闪烁体材料，其具有用于收集闪烁体材料中产生的光的透镜系统。衬底用于将闪烁体材料与透镜系统间隔开。

7. 发明授权

US07057187B1 Scintillator optical system and method of manufacture 有权
标题翻译：闪烁光学系统及其制造方法
公开(公告)号：US07057187B1
公开(公告)日：2006-06-06
申请号：US10704382
申请日：2003-11-07
申请人： Wenbing Yun , Yuxin Wang , David R. Trapp
发明人： Wenbing Yun , Yuxin Wang , David R. Trapp
IPC分类号： G01J1/58
CPC分类号： G01T1/2002 , G01T1/20
摘要： A scintillated CCD detector system for imaging x rays uses x-rays having a photon energy in the range of 1 to 20 keV. The detector differs from existing systems in that it provides extremely high resolution of better than a micrometer, and high detection quantum efficiency of up to 95%. The design of this detector also allows it to function as an energy filter to remove high-energy x-rays. This detector is useful in a wide range of applications including x-ray imaging, spectroscopy, and diffraction. The scintillator optical system has scintillator material with a lens system for collecting the light that is generated in the scintillator material. A substrate is used for spacing the scintillator material from the lens system.
摘要翻译：用于对X射线成像的闪烁CCD检测器系统使用具有在1至20keV范围内的光子能量的X射线。检测器与现有系统不同之处在于它提供比千分尺更高的分辨率，高达95％的高检测量子效率。该检测器的设计也可以用作能量过滤器，以去除高能X射线。该检测器可用于广泛的应用，包括X射线成像，光谱和衍射。闪烁体光学系统具有闪烁体材料，其具有用于收集闪烁体材料中产生的光的透镜系统。衬底用于将闪烁体材料与透镜系统间隔开。

8. 发明授权

US07215736B1 X-ray micro-tomography system optimized for high resolution, throughput, image quality 有权
标题翻译：针对高分辨率，吞吐量，图像质量优化的X射线微层析成像系统
公开(公告)号：US07215736B1
公开(公告)日：2007-05-08
申请号：US11072635
申请日：2005-03-04
申请人： Yuxin Wang , Wenbing Yun , David Dean Scott
发明人： Yuxin Wang , Wenbing Yun , David Dean Scott
IPC分类号： G01N23/00
CPC分类号： G01N23/046 , A61B6/508 , G01N2223/419
摘要： A projection x-ray imaging system that possibly utilizes a laboratory-based micro-focused x-ray source is disclosed. Techniques for optimizing the system for high quality, three dimensional image formation with tomographic imaging with the potential for high resolution and high throughput are described. It also concerns ways to optimize the system design to obtain improved image quality.
摘要翻译：公开了可能利用基于实验室的微焦点x射线源的投影X射线成像系统。描述了用于利用具有高分辨率和高吞吐量的潜力的断层成像优化用于高质量三维图像形成的系统的技术。它还涉及到优化系统设计以获得改进的图像质量的方法。

9. 发明申请

US20080205734A1 X-Ray Micro-Tomography System Optimized for High Resolution, Throughput, Image Quality 有权
标题翻译： X射线微层析成像系统针对高分辨率，吞吐量，图像质量进行了优化
公开(公告)号：US20080205734A1
公开(公告)日：2008-08-28
申请号：US12029790
申请日：2008-02-12
申请人： Yuxin Wang , Wenbing Yun , David Dean Scott
发明人： Yuxin Wang , Wenbing Yun , David Dean Scott
IPC分类号： G06K9/00 , G01N23/00
CPC分类号： G01N23/046 , A61B6/508 , G01N2223/419
摘要： A projection x-ray imaging system that possibly utilizes a laboratory-based micro-focused x-ray source is disclosed. Techniques for optimizing the system for high quality, three dimensional image formation with tomographic imaging with the potential for high resolution and high throughput are described. It also concerns ways to optimize the system design to obtain improved image quality.
摘要翻译：公开了可能利用基于实验室的微焦点x射线源的投影X射线成像系统。描述了用于利用具有高分辨率和高吞吐量的潜力的断层成像优化用于高质量三维图像形成的系统的技术。它还涉及到优化系统设计以获得改进的图像质量的方法。

10. 发明授权

US07286640B2 Dual-band detector system for x-ray imaging of biological samples 有权
标题翻译：用于生物样品X射线成像的双波段检测器系统
公开(公告)号：US07286640B2
公开(公告)日：2007-10-23
申请号：US10990198
申请日：2004-11-16
申请人： Wenbing Yun , Yuxin Wang , David Dean Scott
发明人： Wenbing Yun , Yuxin Wang , David Dean Scott
IPC分类号： H05G1/64 , G01T1/20
CPC分类号： G01T1/202 , G01T1/2018 , G21K2207/005
摘要： A digital dual-band detector functions as an imaging platform capable of extracting hard and soft tissue images, for example. The detector has a first detector system comprising a first scintillator for converting x-rays from a sample to an first optical signal, and a first detector for detecting the first optical signal in combination with a second detector system comprising a second scintillator for converting x-rays from the sample and passing through the first scintillator to a second optical signal, and a second detector for detecting the second optical signal. The detector can facilitate the implementation and deployment of recent developments and can permit low cost practical deployment in clinical applications as well as biomedical research applications where significant improvement in spatial resolution and image contrast is required.
摘要翻译：例如，数字双频带检测器用作能够提取硬和软组织图像的成像平台。检测器具有第一检测器系统，该第一检测器系统包括用于将来自样品的x射线转换成第一光信号的第一闪烁器，以及用于与第二检测器系统一起检测第一光信号的第一检测器，该第二检测器系统包括用于将x- 来自样品的光并通过第一闪烁体到第二光信号;以及第二检测器，用于检测第二光信号。检测器可以促进近期发展的实施和部署，并且可以允许临床应用中的低成本实际部署以及需要显着改善空间分辨率和图像对比度的生物医学研究应用。

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