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1. 发明申请

US20160145244A1 CERTAIN PROTEIN KINASE INHIBITORS 审中-公开
标题翻译：某些蛋白激酶抑制剂
公开(公告)号：US20160145244A1
公开(公告)日：2016-05-26
申请号：US14945426
申请日：2015-11-19
申请人： Weibo Wang , Meiyu Geng , Jian Ding , Xingdong Zhao , Jing Ai , Huajie Zhang , Xia Peng
发明人： Weibo Wang , Meiyu Geng , Jian Ding , Xingdong Zhao , Jing Ai , Huajie Zhang , Xia Peng
IPC分类号： C07D405/14
CPC分类号： C07D405/14
摘要： Provided are certain ALK inhibitors, pharmaceutical compositions thereof, and methods of use therefor.
摘要翻译：提供某些ALK抑制剂，其药物组合物及其用途。

2. 发明申请

US20130324542A1 [1,2,4]TRIAZOLO[4,3-B][1,2,4]TRIAZINE COMPOUNDS, PREPARATION METHOD AND USE THEREOF 审中-公开
标题翻译： [1,2,4]三唑[4,3-B] [1,2,4]三嗪化合物，其制备方法及其用途
公开(公告)号：US20130324542A1
公开(公告)日：2013-12-05
申请号：US13992048
申请日：2011-12-08
申请人： Wenhu Duan , Meiyu Geng , Fang Chen , Jing Ai , Yi Chen , Zhengsheng Zhan , Yongcong Lv , Ying Wang , Jian Ding
发明人： Wenhu Duan , Meiyu Geng , Fang Chen , Jing Ai , Yi Chen , Zhengsheng Zhan , Yongcong Lv , Ying Wang , Jian Ding
IPC分类号： C07D487/04
CPC分类号： C07D487/04
摘要： The present invention relates to a structurally novel [1,2,4]triazolo[4,3-b][1,2,4]triazine compounds represented by formula (I) or formula (II), pharmaceutically acceptable salts thereof, prodrugs thereof, hydrates or solvates thereof, and also relates to a preparation method of the compounds, a pharmaceutical composition including a therapeutically effective amount of the compounds, as well as the use thereof as protein tyrosine kinase inhibitors, particularly as c-Met inhibitors, in the preparation of medicaments for the prevention and/or treatment of diseases associated with c-Met abnormality.
摘要翻译：本发明涉及由式（I）或式（II）表示的结构上新的[1,2,4]三唑并[4,3-b] [1,2,4]三嗪化合物，其药学上可接受的盐，前体药物其还涉及本发明化合物的制备方法，包含治疗有效量的化合物的药物组合物，以及其作为蛋白酪氨酸激酶抑制剂，特别是作为c-Met抑制剂的用途，制备用于预防和/或治疗与c-Met异常有关的疾病的药物。

3. 发明申请

US20140296216A1 PYRIMIDO[4,5-D]PYRIMIDINYL COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF 审中-公开
标题翻译：吡咯二酮[4,5-D]吡啶化合物，药物组合物及其用途
公开(公告)号：US20140296216A1
公开(公告)日：2014-10-02
申请号：US14125304
申请日：2011-12-21
申请人： Ke Ding , Shaohua Chang , Shilin Xu , Lianwen Zhang , Zhengchao Tu , Jian Ding , Meiyu Geng , Yi Chen
发明人： Ke Ding , Shaohua Chang , Shilin Xu , Lianwen Zhang , Zhengchao Tu , Jian Ding , Meiyu Geng , Yi Chen
IPC分类号： C07D487/04
CPC分类号： C07D487/04 , A61K31/519 , A61K31/5377 , A61K31/541 , A61K31/551
摘要： A compound of formula (I) or (II) and use of the compound in the preparation of drugs for treating cancer are disclosed. The study shows that the compounds can inhibit the growth of many kinds of tumor cells, can be used for targeting epidermal growth factor receptor (EGFR), and particularly can inhibit tumor cells with single or multiple mutations of EGFR (T790M). Therefore, the compound can be used as EGFR inhibitor to treat cancer and has a relatively large application value.
摘要翻译：公开了式（I）或（II）的化合物和该化合物在制备用于治疗癌症的药物中的用途。该研究表明，该化合物可抑制多种肿瘤细胞的生长，可用于靶向表皮生长因子受体（EGFR），特别是可以单独或多次EGFR（T790M）突变抑制肿瘤细胞。因此，该化合物可用作EGFR抑制剂治疗癌症，具有较大的应用价值。

4. 外观设计

USD740433S1 Hand-held massaging device 有权
标题翻译：手持按摩器
公开(公告)号：USD740433S1
公开(公告)日：2015-10-06
申请号：US29461275
申请日：2013-07-20
申请人： Megan Zhu , Jian Ding
设计人： Megan Zhu , Jian Ding
CPC分类号： A61H15/0085

5. 发明授权

US08978134B2 Security configuration verification device and method and network system employing the same 有权
标题翻译：安全配置验证装置及采用该方法和网络系统的方法
公开(公告)号：US08978134B2
公开(公告)日：2015-03-10
申请号：US13882579
申请日：2011-11-18
申请人： Baichuan Nie , Jianpeng Sun , Jian Ding , Dong Xu , Zhen Zhou
发明人： Baichuan Nie , Jianpeng Sun , Jian Ding , Dong Xu , Zhen Zhou
IPC分类号： G06F11/10 , H04L29/06
CPC分类号： H04L63/1408 , H04L63/1433
摘要： The invention discloses a security configuration verification device for performing a security configuration verification on a network device, which comprises: one or more preconfigured scanning policies; a scanning policy generator, which selects a scanning policy from the one or more preconfigured scanning policies to generate a new scanning policy corresponding to the network device; and a scanner, which performs the security scanning on the network device with the generated new scanning policy and thereby performs the security configuration verification. The invention also discloses a corresponding security configuration verification method and a network system employing the verification device.
摘要翻译：本发明公开了一种用于在网络设备上执行安全配置验证的安全配置验证设备，包括：一个或多个预配置的扫描策略; 扫描策略生成器，其从所述一个或多个预配置的扫描策略中选择扫描策略，以生成与所述网络设备相对应的新的扫描策略; 以及扫描器，其利用所生成的新扫描策略在网络设备上执行安全扫描，从而执行安全配置验证。本发明还公开了一种对应的安全配置验证方法和采用验证设备的网络系统。

6. 发明授权

US07521000B2 Process for etching photomasks 有权
标题翻译：蚀刻光掩模的工艺
公开(公告)号：US07521000B2
公开(公告)日：2009-04-21
申请号：US10925887
申请日：2004-08-25
申请人： Madhavi R. Chandrachood , Nicole Sandlin , Yung-Hee Yvette Lee , Jian Ding
发明人： Madhavi R. Chandrachood , Nicole Sandlin , Yung-Hee Yvette Lee , Jian Ding
IPC分类号： C03C15/00
CPC分类号： C03C17/06 , C03C2217/26 , C03C2218/33 , C03C2218/34 , C23F4/00 , G03F1/54 , G03F1/80 , H01J37/321 , H01J2237/3341
摘要： Method and apparatus for etching a metal layer disposed on a substrate, such as a photolithographic reticle, are provided. In one aspect, a method is provided for processing a substrate including positioning a substrate having a metal layer disposed on an optically transparent material in a processing chamber, introducing a processing gas processing gas comprising an oxygen containing gas, a chlorine containing gas, and a chlorine-free halogen containing gas, and optionally, an inert gas, into the processing chamber, generating a plasma of the processing gas in the processing chamber, and etching exposed portions of the metal layer disposed on the substrate.
摘要翻译：提供了用于蚀刻设置在诸如光刻掩模之类的基板上的金属层的方法和设备。一方面，提供了一种处理基板的方法，包括：将具有设置在处理室中的光学透明材料上的金属层的基板定位，引入包含含氧气体，含氯气体和将含氯气体的无卤素气体和任选的惰性气体加入到处理室中，在处理室中产生处理气体的等离子体，并蚀刻设置在基板上的金属层的暴露部分。

7. 发明申请

US20060257946A1 Serum biomarkers in ischaemic heart disease 审中-公开
标题翻译：缺血性心脏病血清生物标志物
公开(公告)号：US20060257946A1
公开(公告)日：2006-11-16
申请号：US10559687
申请日：2004-06-04
申请人： Jian Ding , Lee Lomas
发明人： Jian Ding , Lee Lomas
IPC分类号： G01N33/542 , G01N33/53
CPC分类号： G01N33/6887 , G01N33/6893 , G01N2333/4724 , G01N2333/75 , G01N2800/324
摘要： Certain biomarkers and biomarker combinations are useful in a qualifying ischaemic heart disease status in a patient. A diagnostic methodology employing these biomarkers and combinations can distinguish between ischaemic heart disease and normal, as well as between cases of severe myocardial infarction versus mild myocardial infarction.
摘要翻译：某些生物标志物和生物标志物组合在患者的合格缺血性心脏病状态中是有用的。使用这些生物标志物和组合的诊断方法可以区分缺血性心脏病和正常，以及严重心肌梗死与轻度心肌梗死的病例。

8. 发明申请

US20050207569A1 Methods and apparatus for preparing data for encrypted transmission 审中-公开
标题翻译：用于准备加密传输数据的方法和装置
公开(公告)号：US20050207569A1
公开(公告)日：2005-09-22
申请号：US11016479
申请日：2004-12-16
申请人： Ji Zhang , Hain-Ching Liu , Jian Ding
发明人： Ji Zhang , Hain-Ching Liu , Jian Ding
IPC分类号： H04L29/06 , H04N7/167 , H04N7/24 , H04L9/00
CPC分类号： H04L29/06 , H04L29/06027 , H04L63/0428 , H04L65/4084 , H04L65/607 , H04L65/80 , H04N21/23476 , H04N21/6373
摘要： Methods and apparatus for preparing data for encrypted transmission. According to the current invention, a data bitstream may be processed to create side information. After extracting, generating and/or acquiring the side data, some or all of the data bitstream may be encrypted and then combined to create a combined data bitstream, ready for transmission. Subsequently, the combined data bitstream may be transmitted over a network. By processing a data bitstream to extract metadata about the bitstream before encrypting the data, some processing such as splicing, bit rate switching and/or statistical multiplexing done after encryption may be executed without requiring costly de-encryption/re-encryption steps based, in part, on inspecting the contents of the side data. The bitstream may represent video, audio, image or other data types. In some examples according to the current invention, a combined data bitstream may comprise multiple bitstreams, each at a different bit rate.
摘要翻译：用于准备加密传输数据的方法和装置。根据本发明，可以处理数据比特流以创建边信息。在提取，生成和/或获取边数据之后，可以对数据比特流中的一些或全部进行加密，然后组合以产生准备传输的组合数据比特流。随后，组合的数据比特流可以通过网络传输。通过处理数据比特流以在加密数据之前提取关于比特流的元数据，可以在不需要昂贵的去加密/重新加密步骤的情况下执行加密之后完成的诸如拼接，比特率切换和/或统计多路复用的一些处理，部分，检查边数据的内容。比特流可以表示视频，音频，图像或其他数据类型。在根据本发明的一些示例中，组合数据比特流可以包括多个比特流，每个比特流以不同的比特率。

9. 发明授权

US06887895B2 Pseudolaric acid-B derivatives, their preparation and pharmaceutical compositions 失效
标题翻译：假酸B衍生物，其制备方法和药物组合物
公开(公告)号：US06887895B2
公开(公告)日：2005-05-03
申请号：US10486880
申请日：2002-08-14
申请人： Jianmin Yue , Shengping Yang , Jian Ding , Dong Xiao , Shengtao Yuan
发明人： Jianmin Yue , Shengping Yang , Jian Ding , Dong Xiao , Shengtao Yuan
IPC分类号： C07D493/08 , A61K31/365 , A61K31/366 , A61P9/00 , A61P17/00 , A61P31/10 , A61P35/00 , A61P35/04 , C07B61/00 , C07D311/94 , C07D311/78
CPC分类号： A61K31/365 , C07D311/94
摘要： The invention relates to pseudolaric acid-B derivatives of general formula (I), wherein (a) R1 is cyano, heterocyclyl, COXR′ or CON(R″)2, wherein X is O or NH, R′ is H, cycloalkyl, alkyl, heterocyclic alkyl or arylalkyl, each R″ is independently alkyl, cycloalkyl or heterocyclicalkyl; (b) R2 is H, alkylacyl, arylalkylacyl, arylacyl or heterocyclylacyl; (c) R3 is COXY, amino or halogen, wherein X is O or NH, Y is H, NH2, hydroxy, alkyl, cycloalkyl, heterocyclicalkyl, hetroatom-substituted alkyl, tertiary amino-substituted ammonioalkyl, aryl, arylalkyl or polyhydroxyalkyl. The invention also relates to processes for preparing such derivatives and antitumor or antifungal pharmaceutical compositions containing the same.
摘要翻译：本发明涉及通式（I）的假极酸-B衍生物，其中（a）R 1是氰基，杂环基，COXR'或CON（R“）2 其中X是O或NH，R'是H，环烷基，烷基，杂环烷基或芳烷基，每个R“独立地是烷基，环烷基或杂环烷基; （b）R 2是H，烷基酰基，芳基烷基酰基，芳基酰基或杂环基酰基; （c）R 3是COXY，氨基或卤素，其中X是O或NH，Y是H，NH 2，羟基，烷基，环烷基，杂环烷基，杂原子 - 取代的烷基，叔氨基取代的氨基烷基，芳基，芳烷基或聚羟烷基。本发明还涉及制备此类衍生物的方法和含有该衍生物的抗肿瘤或抗真菌药物组合物。

10. 发明授权

US06818140B2 Low ceiling temperature process for a plasma reactor with heated source of a polymer-hardening precursor material 失效
标题翻译：具有聚合物硬化前体材料的加热源的等离子体反应器的低天花板温度过程
公开(公告)号：US06818140B2
公开(公告)日：2004-11-16
申请号：US10002397
申请日：2001-10-31
申请人： Jian Ding
发明人： Jian Ding
IPC分类号： H01L2100
CPC分类号： H01J37/32871 , C23C16/517 , H01F2029/143 , H01J37/32082 , H01J37/321 , H01J37/32146 , H01J37/32165 , H01J37/32458 , H01J37/32467 , H01J37/32522 , H01J37/32688 , H01J37/32706 , H01J2237/3343 , H01J2237/3345 , H01J2237/3346 , H01J2237/3382 , H01L21/31116 , H01L21/6831
摘要： A high plasma density etch process for etching an oxygen-containing layer overlying a non-oxygen containing layer on a workpiece in a plasma reactor chamber, by providing a chamber ceiling overlying the workpiece and containing a semiconductor material, supplying into the chamber a process gas containing etchant precursor species, polymer precursor species and hydrogen, applying plasma source power into the chamber, and cooling the ceiling to a temperature range at or below about 150 degrees C. The etchant and polymer precursor species contain fluorine, and the chamber ceiling semiconductor material includes a fluorine scavenger precursor material. Preferably, the process gas includes at least one of CHF3 and CH2F2. Preferably, the process gas further includes a species including an inert gas, such as HeH2 or Ar. If the chamber is of the type including a heated fluorine scavenger precursor material, this material is heated to well above the polymer condensation temperature, while the ceiling is cooled. In some cases, the plasma source power applicator is an inductive antenna overlying the semiconductor ceiling, and the ceiling has a cooling/heating apparatus contacting the ceiling through semiconductor rings. The inductive antenna in this case constitutes inductive elements between adjacent ones of the semiconductor rings.
摘要翻译：一种高等离子体密度蚀刻工艺，用于在等离子体反应器室中蚀刻覆盖工件上的非含氧层的含氧层，通过提供覆盖在工件上并容纳半导体材料的室顶部，向腔室供应工艺气体包含蚀刻剂前体物质，聚合物前体物质和氢气，将等离子体源功率施加到室中，并将天花板冷却到约150℃或以下的温度范围。蚀刻剂和聚合物前体物质含有氟，并且室顶部半导体材料包括氟清除剂前体材料。优选地，工艺气体包括CHF 3和CH 2 F 2中的至少一种。优选地，处理气体还包括包含惰性气体的物质，例如HeH 2或Ar。如果室是包括加热的氟清除剂前体材料的类型，则将该材料加热到高于聚合物冷凝温度，同时天花板被冷却。在一些情况下，等离子体源功率施加器是覆盖在半导体天花板上的感应天线，天花板具有通过半导体环接触天花板的冷却/加热设备。在这种情况下，感应天线在相邻的半导体环之间构成感应元件。

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