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    • 1. 发明授权
    • Working distance and alignment sensor for a fundus camera
    • 眼底相机的工作距离和对准传感器
    • US07621636B2
    • 2009-11-24
    • US11621943
    • 2007-01-10
    • Wei SuYan ZhouQing Chun ZhaoYeou-Yen Cheng
    • Wei SuYan ZhouQing Chun ZhaoYeou-Yen Cheng
    • A61B3/14A61B3/10
    • A61B3/12A61B3/102A61B3/152
    • In embodiments of optical arrangements of a working distance sensor in a fundus camera that can improve the determination of a correct working distance as well as the transverse positioning of the camera a number of near infrared light sources are arranged to project a number of near infrared illumination beams into the visible light illumination path of the fundus camera and a live view of the retina under near infrared illumination is captured and displayed on a monitor. These embodiments of optical arrangements and associated methods will enable an operator to directly determine if there is any undesirable flare or other artifact appearing within a designated region on the infrared retina view as a result of a wrong alignment of the fundus camera with respect to the eye in terms of not only the working distance but also the horizontal and vertical positions. Pattern recognition algorithms can be used to further enhance the positioning sensitivity of the working distance sensor. An additional iris alignment sensor can be added to achieve a coarse alignment and also function as a measure to determine if the dilation of the iris size is sufficient for different mode of fundus imaging.
    • 在眼底照相机中的工作距离传感器的光学布置的实施例中,其可以改善确定正确的工作距离以及相机的横向定位,并且布置多个近红外光源以投射多个近红外照明 光束进入眼底照相机的可见光照明路径,并且在近红外照明下的视网膜的实时图像被捕获并显示在监视器上。 光学布置和相关方法的这些实施例将使得操作者能够直接确定由于眼底照相机相对于眼睛错误对准的结果,在红外线视网膜视图上的指定区域内是否存在任何不期望的耀斑或其他伪像 不仅在于工作距离,还包括水平和垂直位置。 模式识别算法可用于进一步提高工作距离传感器的定位灵敏度。 可以添加附加的虹膜对准传感器以实现粗略对准,并且还用作确定虹膜尺寸的扩张是否足够用于不同的眼底成像模式的措施。
    • 2. 发明授权
    • Delivering a short Arc lamp light for eye imaging
    • 为眼睛成像提供短弧灯
    • US07621638B2
    • 2009-11-24
    • US11606597
    • 2006-11-29
    • Wei SuYan ZhouYeou-Yen ChengQing Chun Zhao
    • Wei SuYan ZhouYeou-Yen ChengQing Chun Zhao
    • A61B3/10F21V7/00
    • A61B3/0008A61B3/12
    • A light delivery technique includes optical configurations as well as the associated methods that generate a ring beam from a linear light source. In one embodiment, a remote light source module delivers illumination light to a fundus camera and/or slit lamp. In another embodiment, an arrangement combines the use of a light pipe homogenizer and a ring beam transformer for efficiently collecting light from a substantially axially linear light source, homogenizing the collected light that lacks low angle flux relative to the optical axis, and transforming the light into a ring beam with a substantially improved low angle flux distribution. In still another embodiment, light emitted from a substantially axially linear light source is directly collected by a curved surface mirror and spatially filtered into a ring beam. The ring illumination beam can be co-axially projected on a sample such as the pupil of a human eye and at the same time the light beam also has a large enough relatively uniform angular flux distribution so that a wide area on the retina of the eye can be uniformly illuminated.
    • 光输送技术包括光学配置以及从线性光源产生环形光束的相关方法。 在一个实施例中,远程光源模块将照明光传送到眼底照相机和/或裂隙灯。 在另一个实施例中,一种布置结合了光管均质器和环形光束变换器的使用,用于有效地收集来自基本轴向线性光源的光,使收集到的光相互均匀化,所述光相对于光轴缺少低角度通量,以及将光转换 成为具有基本上改进的低角度通量分布的环形梁。 在另一个实施例中,从基本轴向线性光源发射的光直接由弯曲表面镜收集,并在空间上过滤成环形光束。 环形照明光束可以同轴地投射在诸如人眼的瞳孔的样品上,并且同时光束也具有足够大的相对均匀的角度通量分布,使得眼睛的视网膜上的广泛区域 可以均匀照明。
    • 3. 发明申请
    • WORKING DISTANCE AND ALIGNMENT SENSOR FOR A FUNDUS CAMERA
    • FUNDUS CAMERA的工作距离和对准传感器
    • US20080165322A1
    • 2008-07-10
    • US11621943
    • 2007-01-10
    • Wei SuYan ZhouQing Chun ZhaoYeou-Yen Cheng
    • Wei SuYan ZhouQing Chun ZhaoYeou-Yen Cheng
    • A61B3/12
    • A61B3/12A61B3/102A61B3/152
    • In embodiments of optical arrangements of a working distance sensor in a fundus camera that can improve the determination of a correct working distance as well as the transverse positioning of the camera a number of near infrared light sources are arranged to project a number of near infrared illumination beams into the visible light illumination path of the fundus camera and a live view of the retina under near infrared illumination is captured and displayed on a monitor. These embodiments of optical arrangements and associated methods will enable an operator to directly determine if there is any undesirable flare or other artifact appearing within a designated region on the infrared retina view as a result of a wrong alignment of the fundus camera with respect to the eye in terms of not only the working distance but also the horizontal and vertical positions. Pattern recognition algorithms can be used to further enhance the positioning sensitivity of the working distance sensor. An additional iris alignment sensor can be added to achieve a coarse alignment and also function as a measure to determine if the dilation of the iris size is sufficient for different mode of fundus imaging.
    • 在眼底照相机中的工作距离传感器的光学布置的实施例中,其可以改善确定正确的工作距离以及相机的横向定位,并且布置多个近红外光源以投射多个近红外照明 光束进入眼底照相机的可见光照明路径,并且在近红外照明下的视网膜的实时图像被捕获并显示在监视器上。 光学布置和相关方法的这些实施例将使得操作者能够直接确定由于眼底照相机相对于眼睛错误对准的结果,在红外线视网膜视图上的指定区域内是否存在任何不期望的耀斑或其他伪像 不仅在于工作距离,还包括水平和垂直位置。 模式识别算法可用于进一步提高工作距离传感器的定位灵敏度。 可以添加附加的虹膜对准传感器以实现粗略对准,并且还用作确定虹膜尺寸的扩张是否足够用于不同的眼底成像模式的措施。
    • 4. 发明申请
    • Delivering a short Arc lamp light for eye imaging
    • 为眼睛成像提供短弧灯
    • US20080123052A1
    • 2008-05-29
    • US11606597
    • 2006-11-29
    • Wei SuYan ZhouYeou-Yen ChengQing Chun Zhao
    • Wei SuYan ZhouYeou-Yen ChengQing Chun Zhao
    • A61B3/10
    • A61B3/0008A61B3/12
    • A light delivery technique includes optical configurations as well as the associated methods that generate a ring beam from a linear light source. In one embodiment, a remote light source module delivers illumination light to a fundus camera and/or slit lamp. In another embodiment, an arrangement combines the use of a light pipe homogenizer and a ring beam transformer for efficiently collecting light from a substantially axially linear light source, homogenizing the collected light that lacks low angle flux relative to the optical axis, and transforming the light into a ring beam with a substantially improved low angle flux distribution. In still another embodiment, light emitted from a substantially axially linear light source is directly collected by a curved surface mirror and spatially filtered into a ring beam. The ring illumination beam can be co-axially projected on a sample such as the pupil of a human eye and at the same time the light beam also has a large enough relatively uniform angular flux distribution so that a wide area on the retina of the eye can be uniformly illuminated.
    • 光输送技术包括光学配置以及从线性光源产生环形光束的相关方法。 在一个实施例中,远程光源模块将照明光传送到眼底照相机和/或裂隙灯。 在另一个实施例中,一种布置结合了光管均质器和环形光束变换器的使用,用于有效地收集来自基本轴向线性光源的光,使收集到的光相互均匀化,所述光相对于光轴缺少低角度通量,以及将光转换 成为具有基本上改进的低角度通量分布的环形梁。 在另一个实施例中,从基本轴向线性光源发射的光直接由弯曲表面镜收集,并在空间上过滤成环形光束。 环形照明光束可以同轴地投射在诸如人眼的瞳孔的样品上,并且同时光束也具有足够大的相对均匀的角度通量分布,使得眼睛的视网膜上的广泛区域 可以均匀照明。
    • 5. 发明授权
    • Sequential wavefront sensor
    • 顺序波前传感器
    • US07445335B2
    • 2008-11-04
    • US11335980
    • 2006-01-20
    • Wei SuYan ZhouQing Chun Zhao
    • Wei SuYan ZhouQing Chun Zhao
    • A61B3/10
    • G01J9/00A61B3/1015A61B3/14G01J1/0414G01J1/0437
    • A sequential wavefront sensor comprises a light beam scanning module, a sub-wavefront focusing lens, a detector with more than one photosensitive area and a processor for calculating the sequentially obtained centroids of a number focused light spots from the sub-wavefronts to determine the aberration of the input wavefront. A sequential wavefront sensing method comprises the steps of; sequentially projecting a number of sub-wavefronts onto a sub-wavefront focusing lens and a detector with more than one photosensitive areas, calculating the centroid of the focused light spot from each sub-wavefront, and processing the centroid information to determine the aberration of the wavefront. In particular, a method for auto-focusing and/or auto-astigmatism-correction comprises the steps of sequentially projecting a number of sub-wavefronts around an annular ring of a wavefront to a sub-wavefront focusing lens and a detector, calculating the centroid of focused light spot from each sub-wavefront to figure out the centroid trace and hence the defocus and/or astigmatism, adjusting the focus and/or astigmatism of the optical imaging system before the wavefront sensor so that the measured defocus and/or astigmatism is minimized.
    • 顺序波前传感器包括光束扫描模块,子波前聚焦透镜,具有多于一个感光区域的检测器和用于计算来自子波前的数量聚焦光点的顺序获得的质心的处理器,以确定像差 的输入波前。 顺序波前感测方法包括以下步骤: 顺序地将多个子波前投影到子波前聚焦透镜和具有多于一个感光区域的检测器,计算来自每个子波前的聚焦光点的质心,以及处理质心信息以确定 波前。 特别地,一种用于自动聚焦和/或自动像散校正的方法包括以下步骤:将多个子波前围绕波前的环形环顺序地投影到子波前聚焦透镜和检测器,计算质心 来自每个子波前的聚焦光点,以计算出质心轨迹,从而计算散焦和/或散光,调整光学成像系统在波前传感器之前的焦点和/或散光,使得测量的散焦和/或散光为 最小化。
    • 10. 发明申请
    • Sequential wavefront sensor
    • 顺序波前传感器
    • US20070171366A1
    • 2007-07-26
    • US11335980
    • 2006-01-20
    • Wei SuYan ZhouQing Zhao
    • Wei SuYan ZhouQing Zhao
    • A61B3/10
    • G01J9/00A61B3/1015A61B3/14G01J1/0414G01J1/0437
    • A sequential wavefront sensor comprises a light beam scanning module, a sub-wavefront focusing lens, a detector with more than one photosensitive area and a processor for calculating the sequentially obtained centroids of a number focused light spots from the sub-wavefronts to determine the aberration of the input wavefront. A sequential wavefront sensing method comprises the steps of; sequentially projecting a number of sub-wavefronts onto a sub-wavefront focusing lens and a detector with more than one photosensitive areas, calculating the centroid of the focused light spot from each sub-wavefront, and processing the centroid information to determine the aberration of the wavefront. In particular, a method for auto-focusing and/or auto-astigmatism-correction comprises the steps of sequentially projecting a number of sub-wavefronts around an annular ring of a wavefront to a sub-wavefront focusing lens and a detector, calculating the centroid of focused light spot from each sub-wavefront to figure out the centroid trace and hence the defocus and/or astigmatism, adjusting the focus and/or astigmatism of the optical imaging system before the wavefront sensor so that the measured defocus and/or astigmatism is minimized.
    • 顺序波前传感器包括光束扫描模块,子波前聚焦透镜,具有多于一个感光区域的检测器和用于计算来自子波前的数量聚焦光点的顺序获得的质心的处理器,以确定像差 的输入波前。 顺序波前感测方法包括以下步骤: 顺序地将多个子波前投影到子波前聚焦透镜和具有多于一个感光区域的检测器,计算来自每个子波前的聚焦光点的质心,以及处理质心信息以确定 波前。 特别地,一种用于自动聚焦和/或自动像散校正的方法包括以下步骤:将多个子波前围绕波前的环形环顺序地投影到子波前聚焦透镜和检测器,计算质心 来自每个子波前的聚焦光点,以计算出质心轨迹,从而计算散焦和/或散光,调整光学成像系统在波前传感器之前的焦点和/或散光,使得测量的散焦和/或散光为 最小化。